Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysosomal alpha-glucosidase (Mus musculus (Mouse)) | BDBM190539 (US9181184, 26) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 6.60E+3 | n/a | n/a | 4.0 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho... | US Patent US9181184 (2015) BindingDB Entry DOI: 10.7270/Q2T43RWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Mus musculus (Mouse)) | BDBM18364 ((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-nonylpiperidi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | n/a | n/a | 7.00E+3 | n/a | n/a | 4.0 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho... | US Patent US9181184 (2015) BindingDB Entry DOI: 10.7270/Q2T43RWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Mus musculus (Mouse)) | BDBM18355 ((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | n/a | n/a | 1.18E+4 | n/a | n/a | 4.0 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho... | US Patent US9181184 (2015) BindingDB Entry DOI: 10.7270/Q2T43RWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Mus musculus (Mouse)) | BDBM190540 (US9181184, 27) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 1.73E+4 | n/a | n/a | 4.0 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho... | US Patent US9181184 (2015) BindingDB Entry DOI: 10.7270/Q2T43RWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Mus musculus (Mouse)) | BDBM190528 (US9181184, 11) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 4.77E+4 | n/a | n/a | 4.0 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho... | US Patent US9181184 (2015) BindingDB Entry DOI: 10.7270/Q2T43RWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Mus musculus (Mouse)) | BDBM190538 (US9181184, 25) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6.65E+4 | n/a | n/a | 4.0 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho... | US Patent US9181184 (2015) BindingDB Entry DOI: 10.7270/Q2T43RWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Mus musculus (Mouse)) | BDBM190530 (US9181184, 16) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6.97E+4 | n/a | n/a | 4.0 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho... | US Patent US9181184 (2015) BindingDB Entry DOI: 10.7270/Q2T43RWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Mus musculus (Mouse)) | BDBM18353 ((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | n/a | n/a | 7.45E+4 | n/a | n/a | 4.0 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho... | US Patent US9181184 (2015) BindingDB Entry DOI: 10.7270/Q2T43RWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Mus musculus (Mouse)) | BDBM190537 (US9181184, 24) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 7.71E+4 | n/a | n/a | 4.0 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho... | US Patent US9181184 (2015) BindingDB Entry DOI: 10.7270/Q2T43RWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Mus musculus (Mouse)) | BDBM18351 ((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | n/a | n/a | 9.88E+4 | n/a | n/a | 4.0 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho... | US Patent US9181184 (2015) BindingDB Entry DOI: 10.7270/Q2T43RWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Mus musculus (Mouse)) | BDBM190531 (US9181184, 17 | US9181184, 18) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 1.04E+5 | n/a | n/a | 4.0 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho... | US Patent US9181184 (2015) BindingDB Entry DOI: 10.7270/Q2T43RWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Mus musculus (Mouse)) | BDBM190536 (US9181184, 23) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 1.21E+5 | n/a | n/a | 4.0 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho... | US Patent US9181184 (2015) BindingDB Entry DOI: 10.7270/Q2T43RWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Mus musculus (Mouse)) | BDBM190535 (US9181184, 21) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 2.10E+5 | n/a | n/a | 4.0 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho... | US Patent US9181184 (2015) BindingDB Entry DOI: 10.7270/Q2T43RWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Mus musculus (Mouse)) | BDBM50259956 (2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol | CHE...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | n/a | n/a | 2.81E+5 | n/a | n/a | 4.0 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho... | US Patent US9181184 (2015) BindingDB Entry DOI: 10.7270/Q2T43RWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Mus musculus (Mouse)) | BDBM190533 (US9181184, 19) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 3.72E+5 | n/a | n/a | 4.0 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho... | US Patent US9181184 (2015) BindingDB Entry DOI: 10.7270/Q2T43RWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Mus musculus (Mouse)) | BDBM190534 (US9181184, 20) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 4.68E+5 | n/a | n/a | 4.0 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho... | US Patent US9181184 (2015) BindingDB Entry DOI: 10.7270/Q2T43RWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Mus musculus (Mouse)) | BDBM190529 (US9181184, 15) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 5.84E+5 | n/a | n/a | 4.0 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho... | US Patent US9181184 (2015) BindingDB Entry DOI: 10.7270/Q2T43RWB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Mus musculus (Mouse)) | BDBM190531 (US9181184, 17 | US9181184, 18) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 6.53E+5 | n/a | n/a | 4.0 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho... | US Patent US9181184 (2015) BindingDB Entry DOI: 10.7270/Q2T43RWB | |||||||||||
More data for this Ligand-Target Pair |