Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50163942 ((Z)-7-[(1R,4S,5R)-5-Hydroxy-2-((R)-3-hydroxy-3-met...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a |
Florida Institute of Technology Curated by ChEMBL | Assay Description Effective concentration DP2 mediated expression of the adhesion molecule CD11b in eosinophils | Bioorg Med Chem Lett 15: 1873-6 (2005) Article DOI: 10.1016/j.bmcl.2005.02.011 BindingDB Entry DOI: 10.7270/Q2WQ0396 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50163942 ((Z)-7-[(1R,4S,5R)-5-Hydroxy-2-((R)-3-hydroxy-3-met...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a |
Florida Institute of Technology Curated by ChEMBL | Assay Description Effective concentration for DP2 mediated chemotaxis in eosinophils | Bioorg Med Chem Lett 15: 1873-6 (2005) Article DOI: 10.1016/j.bmcl.2005.02.011 BindingDB Entry DOI: 10.7270/Q2WQ0396 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM231198 (US9556139, 106 Enantiomer 2 106) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.65 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50163942 ((Z)-7-[(1R,4S,5R)-5-Hydroxy-2-((R)-3-hydroxy-3-met...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a |
Florida Institute of Technology Curated by ChEMBL | Assay Description Effective concentration for DP2 mediated stimulation of actin polymerization in eosinophils | Bioorg Med Chem Lett 15: 1873-6 (2005) Article DOI: 10.1016/j.bmcl.2005.02.011 BindingDB Entry DOI: 10.7270/Q2WQ0396 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM231191 (Sodium 6-chloro-7-(4-(4-chloro-2-methoxyphenethylc...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 5.10 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM231168 (6-Cyano-7-(4-(naphthalen-2-ylcarbamoyl)phenoxy)chr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6.70 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50163943 ((Z)-7-[(1R,2R,5S)-5-Hydroxy-2-((E)-(S)-3-hydroxy-o...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 7 | n/a | n/a | n/a | n/a |
Florida Institute of Technology Curated by ChEMBL | Assay Description Effective concentration DP2 mediated expression of the adhesion molecule CD11b in eosinophils | Bioorg Med Chem Lett 15: 1873-6 (2005) Article DOI: 10.1016/j.bmcl.2005.02.011 BindingDB Entry DOI: 10.7270/Q2WQ0396 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM231194 (Sodium 6-chloro-7-(4-(2-methoxy-4-(trifluoromethyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 7.70 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM230043 (US9556139, 11 Enantiomer 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 9.30 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50163943 ((Z)-7-[(1R,2R,5S)-5-Hydroxy-2-((E)-(S)-3-hydroxy-o...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
Florida Institute of Technology Curated by ChEMBL | Assay Description Effective concentration for DP2 mediated chemotaxis in eosinophils | Bioorg Med Chem Lett 15: 1873-6 (2005) Article DOI: 10.1016/j.bmcl.2005.02.011 BindingDB Entry DOI: 10.7270/Q2WQ0396 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM230066 (Sodium 6-chloro-7-(4-(4-chloro-2-cyclopropylphenet...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 10.5 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM228438 (Ethyl 6-chloro-7-hydroxychroman-4-carboxylate | US...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 10.7 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50312283 ((+/-)-cis-N-(1-benzoyl-2-methyl-1,2,3,4-tetrahydro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Antagonist activity at human CRTH2 receptor expressed in CEM cell assessed as inhibition of PGD2-induced cell migration after 3 hrs by transwell migr... | Bioorg Med Chem Lett 19: 6840-4 (2009) Article DOI: 10.1016/j.bmcl.2009.10.094 BindingDB Entry DOI: 10.7270/Q2N58MHF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM230543 (7-(4-((4-(Trifluoromethyl)phenethyl)carbamoyl)phen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 11 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM234930 (6-Chloro-7-(4-(4-chloro-2-hydroxyphenethylcarbamoy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 11.1 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM231155 (6-Cyano-7-(4-(4-(trifluoromethyl)phenylcarbamoyl)p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 11.9 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM230069 (Sodium 6-chloro-7-(4-(2,4-dichloro-6-methoxyphenet...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 12 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50458655 (CHEMBL4207377) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a |
Merck Research Laboratory Curated by ChEMBL | Assay Description Agonist activity at human CRTh2 expressed in HEK cells assessed as forskolin-induced intracellular cAMP accumulation by ELISA based chemiluminescence... | ACS Med Chem Lett 9: 679-684 (2018) Article DOI: 10.1021/acsmedchemlett.8b00145 BindingDB Entry DOI: 10.7270/Q2F47RRN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM230608 (7-(4-((2-(4-Chlorophenyl)cyclopropyl)carbamoyl)phe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 12.1 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM230643 (6-Cyano-7-(4-(2-(naphthalen-1-yl)ethylcarbamoyl)ph...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 12.1 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM230079 (7-(4-((2-Phenylcyclopropyl)carbamoyl)phenoxy)-6-cy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 12.1 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50163943 ((Z)-7-[(1R,2R,5S)-5-Hydroxy-2-((E)-(S)-3-hydroxy-o...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
Florida Institute of Technology Curated by ChEMBL | Assay Description Effective concentration for DP2 mediated stimulation of actin polymerization in eosinophils | Bioorg Med Chem Lett 15: 1873-6 (2005) Article DOI: 10.1016/j.bmcl.2005.02.011 BindingDB Entry DOI: 10.7270/Q2WQ0396 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM230042 (6-Chloro-7-(4-(4-chlorophenethylcarbamoyl)phenoxy)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 13.9 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM230644 (6-Cyano-7-(4-(2-(naphthalen-2-yl)ethylcarbamoyl)ph...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 14.2 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM230608 (7-(4-((2-(4-Chlorophenyl)cyclopropyl)carbamoyl)phe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 14.8 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM230078 (Sodium 6,8-dichloro-7-(4-(4-chlorophenethylcarbamo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 15.8 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM230040 (2-(4-Chloro-2-methoxyphenyl)ethanamine | US9556139...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 16 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM234939 (US9556139, 238 Enantiomer 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 16.2 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM232977 (Sodium 6-chloro-7-(4-(2,4-dimethoxyphenethylcarbam...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 16.4 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM228392 (6-Cyano-7-(4-(4-chlorophenylcarbamoyl)phenoxy)chro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 16.6 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM234933 (US9556139, 235 Enantiomer 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 17 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM230068 (Sodium 6-chloro-7-(4-(4-cyclopropyl-2-methoxyphene...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 17.3 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM230645 (7-(4-(4-tert-Butylphenethylcarbamoyl)phenoxy)-6-cy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 18.9 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM21599 (2-{5-chloro-1'-[(3-methyl-5-phenyl-1,2-oxazol-4-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 3.80 | n/a | n/a | n/a | 19 | n/a | n/a | n/a | n/a |
Merck Serono | Assay Description A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc... | J Med Chem 51: 2227-2243 (2008) Article DOI: 10.1021/jm701383e BindingDB Entry DOI: 10.7270/Q22R3PZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM230039 (US9556139, 7) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 19 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM21594 (2-{5-chloro-1'-[(5-methyl-3-phenyl-1,2-oxazol-4-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 7.60 | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a |
Merck Serono | Assay Description A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc... | J Med Chem 51: 2227-2243 (2008) Article DOI: 10.1021/jm701383e BindingDB Entry DOI: 10.7270/Q22R3PZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM234931 (US9556139, 234 Enantiomer 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 21.7 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM231253 (7-(4-(4-Chlorophenethylcarbamoyl)-2-methylphenoxy)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 21.9 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM230498 (7-(4-((4-Fluorophenethyl)carbamoyl)phenoxy)-6-cyan...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 22.5 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM21595 (2-{5-chloro-1'-[(3-methyl-5-phenyl-1,2-oxazol-4-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 5.30 | n/a | n/a | n/a | 23 | n/a | n/a | n/a | n/a |
Merck Serono | Assay Description A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc... | J Med Chem 51: 2227-2243 (2008) Article DOI: 10.1021/jm701383e BindingDB Entry DOI: 10.7270/Q22R3PZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM231153 (7-(4-(4-Chlorophenylcarbamoyl)phenoxy)-6-cyanochro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 23.3 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50296977 (2-(5-fluoro-2-methyl-3-(quinolin-2-ylmethyl)-1H-in...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 24 | n/a | n/a | n/a | n/a |
Oxagen Ltd. Curated by ChEMBL | Assay Description Antagonist activity at CRTH2 in human eosinophils assessed as inhibition of PGD2-induced shape change | J Med Chem 55: 2915-31 (2012) Article DOI: 10.1021/jm2013997 BindingDB Entry DOI: 10.7270/Q2Z0398R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM234937 (US9556139, 237 Enantiomer 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 25.6 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM231500 (6-Cyano-7-(4-((R)-2-phenylpropylcarbamoyl)phenoxy)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 25.7 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM234904 (US9556139, 207 | sodium 6-chloro-7-(4-(4-chloro-2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 26.4 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM230080 (7-(4-((3-Methoxyphenethyl)carbamoyl)phenoxy)-6-cya...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 30.7 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM234935 (US9556139, 236 Enantiomer 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 34 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM231147 (6-Cyano-7-(4-(1,2,3,4-tetrahydronaphthalen-2-ylcar...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 36.4 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM234908 (US9556139, 211 | sodium 6-chloro-7-(4-(4-chloro- 2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 37.2 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM230037 (6-Cyano-7-(4-(phenethylcarbamoyl)phenoxy)chroman-4...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 37.4 | n/a | n/a | 7.4 | 25 |
Array BioPharma Inc. US Patent | Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai... | US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q | |||||||||||
More data for this Ligand-Target Pair |
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