Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50205233 ((20S,22R)-22-methyl-1-alpha-25-dihydroxy-vitamin D...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.00200 | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Induction of transactivation of human VDR responsive gene in COS7 cells by rat osteopontin luciferase reporter gene assay | J Med Chem 50: 932-9 (2007) Article DOI: 10.1021/jm060889f BindingDB Entry DOI: 10.7270/Q2Z320FX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Mus musculus) | BDBM50005618 (CHEMBL2021484) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.00210 | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assay | Bioorg Med Chem 16: 6949-64 (2008) Article DOI: 10.1016/j.bmc.2008.05.043 BindingDB Entry DOI: 10.7270/Q2Z60NWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50205234 ((20S,22R)-22-methyl-1-alpha-25-dihydroxy-vitamin D...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.00300 | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Induction of transactivation of human VDR responsive gene in COS7 cells by rat osteopontin luciferase reporter gene assay | J Med Chem 50: 932-9 (2007) Article DOI: 10.1021/jm060889f BindingDB Entry DOI: 10.7270/Q2Z320FX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50200182 ((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | n/a | n/a | 0.0100 | n/a | n/a | n/a | n/a |
National Institute of Health Sciences Curated by ChEMBL | Assay Description Activity at human VDR expressed in human HOS cells transfected with pGL3-hOc, pCDNA-hVDR and phRL-TK assessed as assessed as transcriptional activati... | Bioorg Med Chem Lett 21: 6104-7 (2011) Article DOI: 10.1016/j.bmcl.2011.08.047 BindingDB Entry DOI: 10.7270/Q29C6XTD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50437338 (CHEMBL2407821) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.0100 | n/a | n/a | n/a | n/a |
Teikyo University Curated by ChEMBL | Assay Description Transactivation of VDR-mediated osteocalcin promoter in human HOS/SF cells after 24 hrs by luciferase reporter gene assay | ACS Med Chem Lett 4: 671-4 (2013) Article DOI: 10.1021/ml400098w BindingDB Entry DOI: 10.7270/Q2959JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50200182 ((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | n/a | n/a | 0.0106 | n/a | n/a | n/a | n/a |
National Institute of Health Sciences Curated by ChEMBL | Assay Description Effect on VDR transcriptional activity in human osteosarcoma cells | Bioorg Med Chem Lett 18: 120-3 (2008) Article DOI: 10.1016/j.bmcl.2007.11.007 BindingDB Entry DOI: 10.7270/Q2Q2414J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50200182 ((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | n/a | n/a | 0.0110 | n/a | n/a | n/a | n/a |
National Institute of Health Sciences Curated by ChEMBL | Assay Description Agonist activity at human VDR expressed in HOS cells co-expressing human RXR by Dual-Glo luciferase reporter gene assay | Bioorg Med Chem 26: 6146-6152 (2018) Article DOI: 10.1016/j.bmc.2018.11.008 BindingDB Entry DOI: 10.7270/Q25T3PWH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50565949 (CHEMBL4794075) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.0140 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human VDR expressed in HEK293 cells expressing mouse osteopontin VDRE assessed as induction of receptor transactivation incubated... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01420 BindingDB Entry DOI: 10.7270/Q26D5XQ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Mus musculus) | BDBM50244268 ((20S)-1-alpha-2-alpha-25-Trihydroxy-2beta-methyl-1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0170 | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assay | Bioorg Med Chem 16: 6949-64 (2008) Article DOI: 10.1016/j.bmc.2008.05.043 BindingDB Entry DOI: 10.7270/Q2Z60NWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50292706 ((1R,3R,7E,17beta)-17-{(1R,2E,4R)-4-hydroxy-1-methy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Agonist activity at VDR assessed as receptor transactivation by transient transcription assay | J Med Chem 51: 5320-9 (2008) Article DOI: 10.1021/jm8004477 BindingDB Entry DOI: 10.7270/Q28C9W2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Mus musculus) | BDBM50244165 ((1R,2S,3R,5Z,7E)-17-{(1R)-1-[(2-ethyl-2-hydroxybut...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0240 | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assay | Bioorg Med Chem 16: 6949-64 (2008) Article DOI: 10.1016/j.bmc.2008.05.043 BindingDB Entry DOI: 10.7270/Q2Z60NWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50200182 ((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | n/a | n/a | 0.0260 | n/a | n/a | n/a | n/a |
Teikyo University Curated by ChEMBL | Assay Description Transactivation of VDR-mediated osteocalcin promoter in human HOS/SF cells after 24 hrs by luciferase reporter gene assay | ACS Med Chem Lett 4: 671-4 (2013) Article DOI: 10.1021/ml400098w BindingDB Entry DOI: 10.7270/Q2959JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Mus musculus) | BDBM50244240 ((20S)-(2E)-1-alpha-25-Dihydroxy-2-[2-(hydroxy)-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0260 | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assay | Bioorg Med Chem 16: 6949-64 (2008) Article DOI: 10.1016/j.bmc.2008.05.043 BindingDB Entry DOI: 10.7270/Q2Z60NWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Mus musculus) | BDBM50244164 ((20S)-1-alpha-25-Dihydroxy-2-alpha-(2-hydroxyethox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0270 | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assay | Bioorg Med Chem 16: 6949-64 (2008) Article DOI: 10.1016/j.bmc.2008.05.043 BindingDB Entry DOI: 10.7270/Q2Z60NWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Mus musculus) | BDBM50244241 ((20R)-(2E)-1-alpha-25-Dihydroxy-2-[2-(hydroxy)-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0290 | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assay | Bioorg Med Chem 16: 6949-64 (2008) Article DOI: 10.1016/j.bmc.2008.05.043 BindingDB Entry DOI: 10.7270/Q2Z60NWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50281390 (CHEMBL4159525) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a |
Universidad de Santiago de Compostela Curated by ChEMBL | Assay Description Transactivation of VDR (unknown origin) expressed in HEK293 cells harboring TK-Spp X 3-LUC reporter plasmid after 24 hrs by luciferase reporter gene ... | J Med Chem 61: 6658-6673 (2018) Article DOI: 10.1021/acs.jmedchem.8b00427 BindingDB Entry DOI: 10.7270/Q2M04801 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Mus musculus) | BDBM50412386 (CHEMBL2021486) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assay | Bioorg Med Chem 16: 6949-64 (2008) Article DOI: 10.1016/j.bmc.2008.05.043 BindingDB Entry DOI: 10.7270/Q2Z60NWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50329706 ((2S)-3-{4-[1-ethyl-1-(4-{[(2R)-2-hydroxy-3,3-dimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0396 | n/a | n/a | n/a | n/a |
National Institute of Health Sciences Curated by ChEMBL | Assay Description Effect on VDR transcriptional activity in human osteosarcoma cells | Bioorg Med Chem Lett 18: 120-3 (2008) Article DOI: 10.1016/j.bmcl.2007.11.007 BindingDB Entry DOI: 10.7270/Q2Q2414J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50329706 ((2S)-3-{4-[1-ethyl-1-(4-{[(2R)-2-hydroxy-3,3-dimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a |
National Institute of Health Sciences Curated by ChEMBL | Assay Description Activity at human VDR expressed in human HOS cells transfected with pGL3-hOc, pCDNA-hVDR and phRL-TK assessed as assessed as transcriptional activati... | Bioorg Med Chem Lett 21: 6104-7 (2011) Article DOI: 10.1016/j.bmcl.2011.08.047 BindingDB Entry DOI: 10.7270/Q29C6XTD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50329706 ((2S)-3-{4-[1-ethyl-1-(4-{[(2R)-2-hydroxy-3,3-dimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a |
National Institute of Health Sciences Curated by ChEMBL | Assay Description Agonist activity at human VDR expressed in HOS cells co-expressing human RXR by Dual-Glo luciferase reporter gene assay | Bioorg Med Chem 26: 6146-6152 (2018) Article DOI: 10.1016/j.bmc.2018.11.008 BindingDB Entry DOI: 10.7270/Q25T3PWH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50437335 (CHEMBL2407824) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.0440 | n/a | n/a | n/a | n/a |
Teikyo University Curated by ChEMBL | Assay Description Transactivation of VDR-mediated osteocalcin promoter in human HOS/SF cells after 24 hrs by luciferase reporter gene assay | ACS Med Chem Lett 4: 671-4 (2013) Article DOI: 10.1021/ml400098w BindingDB Entry DOI: 10.7270/Q2959JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Mus musculus) | BDBM50412386 (CHEMBL2021486) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0580 | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assay | Bioorg Med Chem 16: 6949-64 (2008) Article DOI: 10.1016/j.bmc.2008.05.043 BindingDB Entry DOI: 10.7270/Q2Z60NWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50354990 (CHEMBL1834893) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0600 | n/a | n/a | n/a | n/a |
National Institute of Health Sciences Curated by ChEMBL | Assay Description Activity at human VDR expressed in human HOS cells transfected with pGL3-hOc, pCDNA-hVDR and phRL-TK assessed as assessed as transcriptional activati... | Bioorg Med Chem Lett 21: 6104-7 (2011) Article DOI: 10.1016/j.bmcl.2011.08.047 BindingDB Entry DOI: 10.7270/Q29C6XTD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50200182 ((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | n/a | n/a | 0.0700 | n/a | n/a | n/a | n/a |
Universidad de Santiago de Compostela Curated by ChEMBL | Assay Description Transactivation of VP16-tagged VDR (unknown origin) expressed in HEK293 cells harboring pCMX-GAL4-RXRalpha and MH100(UAS) X 4tk-LUC reporter plasmid ... | J Med Chem 61: 6658-6673 (2018) Article DOI: 10.1021/acs.jmedchem.8b00427 BindingDB Entry DOI: 10.7270/Q2M04801 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50015318 (CHEMBL3263871) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0700 | n/a | n/a | n/a | n/a |
Rikkyo University Curated by ChEMBL | Assay Description Transactivation of human VDR expressed in HEK293 cells cotransfected with mouse VDRE, Tk-Sppx3-LUC reporter plasmid measured after 24 hrs by lucifera... | J Med Chem 57: 4073-87 (2014) Article DOI: 10.1021/jm401989c BindingDB Entry DOI: 10.7270/Q2ZS2Z2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50198707 ((2E)-(20S)-1alpha,25-dihydroxy-2-[2''-(fluoroethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0700 | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Inhibition of human VDR induced-transcriptional transactivation of luciferase reporter gene in COS7 cells after 24 hrs | Bioorg Med Chem 15: 1475-82 (2007) Article DOI: 10.1016/j.bmc.2006.10.069 BindingDB Entry DOI: 10.7270/Q2TT4QK5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Mus musculus) | BDBM50244240 ((20S)-(2E)-1-alpha-25-Dihydroxy-2-[2-(hydroxy)-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0850 | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assay | Bioorg Med Chem 16: 6949-64 (2008) Article DOI: 10.1016/j.bmc.2008.05.043 BindingDB Entry DOI: 10.7270/Q2Z60NWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Mus musculus) | BDBM50412385 (CHEMBL2021488) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0900 | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assay | Bioorg Med Chem 16: 6949-64 (2008) Article DOI: 10.1016/j.bmc.2008.05.043 BindingDB Entry DOI: 10.7270/Q2Z60NWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Mus musculus) | BDBM50412385 (CHEMBL2021488) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0900 | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assay | Bioorg Med Chem 16: 6949-64 (2008) Article DOI: 10.1016/j.bmc.2008.05.043 BindingDB Entry DOI: 10.7270/Q2Z60NWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50200182 ((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human VDR | Citation and Details Article DOI: 10.1021/acs.jmedchem.6b01126 BindingDB Entry DOI: 10.7270/Q2DF6VVN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Mus musculus) | BDBM50244165 ((1R,2S,3R,5Z,7E)-17-{(1R)-1-[(2-ethyl-2-hydroxybut...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.115 | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assay | Bioorg Med Chem 16: 6949-64 (2008) Article DOI: 10.1016/j.bmc.2008.05.043 BindingDB Entry DOI: 10.7270/Q2Z60NWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Mus musculus) | BDBM50244269 ((20R)-1-alpha-2-alpha-25-Trihydroxy-2-beta-methyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.120 | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assay | Bioorg Med Chem 16: 6949-64 (2008) Article DOI: 10.1016/j.bmc.2008.05.043 BindingDB Entry DOI: 10.7270/Q2Z60NWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50200182 ((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | n/a | n/a | 0.120 | n/a | n/a | n/a | n/a |
Rikkyo University Curated by ChEMBL | Assay Description Agonist activity at VDR in human HEK293 cells assessed as transcriptional activity after 16 to 24 hrs by luciferase reporter gene assay | J Med Chem 58: 9510-21 (2015) Article DOI: 10.1021/acs.jmedchem.5b00792 BindingDB Entry DOI: 10.7270/Q22V2HZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50281390 (CHEMBL4159525) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.140 | n/a | n/a | n/a | n/a |
Universidad de Santiago de Compostela Curated by ChEMBL | Assay Description Transactivation of VP16-tagged VDR (unknown origin) expressed in HEK293 cells harboring pCMX-GAL4-RXRalpha and MH100(UAS) X 4tk-LUC reporter plasmid ... | J Med Chem 61: 6658-6673 (2018) Article DOI: 10.1021/acs.jmedchem.8b00427 BindingDB Entry DOI: 10.7270/Q2M04801 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50437336 (CHEMBL2407823) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.150 | n/a | n/a | n/a | n/a |
Teikyo University Curated by ChEMBL | Assay Description Transactivation of VDR-mediated osteocalcin promoter in human HOS/SF cells after 24 hrs by luciferase reporter gene assay | ACS Med Chem Lett 4: 671-4 (2013) Article DOI: 10.1021/ml400098w BindingDB Entry DOI: 10.7270/Q2959JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50565950 (CHEMBL4776651) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.150 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human VDR expressed in HEK293 cells expressing mouse osteopontin VDRE assessed as induction of receptor transactivation incubated... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01420 BindingDB Entry DOI: 10.7270/Q26D5XQ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50143770 ((1R,3S)-5-[2-[(3aS,7aR)-1-((R)-5-Hydroxy-1,5-dimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.180 | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Effective concentration required for inhibition of Vitamin D3 receptor | J Med Chem 47: 1956-61 (2004) Article DOI: 10.1021/jm0310582 BindingDB Entry DOI: 10.7270/Q2Q81CHJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Mus musculus) | BDBM50244241 ((20R)-(2E)-1-alpha-25-Dihydroxy-2-[2-(hydroxy)-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assay | Bioorg Med Chem 16: 6949-64 (2008) Article DOI: 10.1016/j.bmc.2008.05.043 BindingDB Entry DOI: 10.7270/Q2Z60NWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50205235 ((20S,22R)-22-methyl-1-alpha-25-dihydroxy-vitamin D...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Induction of transactivation of human VDR responsive gene in COS7 cells by rat osteopontin luciferase reporter gene assay | J Med Chem 50: 932-9 (2007) Article DOI: 10.1021/jm060889f BindingDB Entry DOI: 10.7270/Q2Z320FX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50030475 (7-Dehydrocholesterol | CHEBI:28940 | Cholecalcifer...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars | DrugBank Article PubMed | n/a | n/a | n/a | n/a | 0.210 | n/a | n/a | n/a | n/a |
Phenex Pharmaceuticals AG Curated by ChEMBL | Assay Description Agonist activity at human VDR expressed in HEK293 cells by luciferase reporter gene assay | Bioorg Med Chem Lett 24: 5265-7 (2014) Article DOI: 10.1016/j.bmcl.2014.09.053 BindingDB Entry DOI: 10.7270/Q2S46TKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50437334 (CHEMBL2407825) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.210 | n/a | n/a | n/a | n/a |
Teikyo University Curated by ChEMBL | Assay Description Transactivation of VDR-mediated osteocalcin promoter in human HOS/SF cells after 24 hrs by luciferase reporter gene assay | ACS Med Chem Lett 4: 671-4 (2013) Article DOI: 10.1021/ml400098w BindingDB Entry DOI: 10.7270/Q2959JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50565949 (CHEMBL4794075) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.240 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human VDR expressed in African green monkey COS7 cells expressing mouse osteopontin VDRE assessed as induction of receptor transa... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01420 BindingDB Entry DOI: 10.7270/Q26D5XQ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50437337 (CHEMBL2407822) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.290 | n/a | n/a | n/a | n/a |
Teikyo University Curated by ChEMBL | Assay Description Transactivation of VDR-mediated osteocalcin promoter in human HOS/SF cells after 24 hrs by luciferase reporter gene assay | ACS Med Chem Lett 4: 671-4 (2013) Article DOI: 10.1021/ml400098w BindingDB Entry DOI: 10.7270/Q2959JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50200182 ((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a |
Palacky University in Olomouc Curated by ChEMBL | Assay Description Agonist activity at VDR expressed in human HuH7 cells after 24 hrs by pDR3-luciferase reporter gene assay | J Med Chem 59: 4601-10 (2016) Article DOI: 10.1021/acs.jmedchem.5b01891 BindingDB Entry DOI: 10.7270/Q2D220JZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50409927 (CHEMBL2112315) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.350 | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Effective concentration required for inhibition of Vitamin D3 receptor | J Med Chem 47: 1956-61 (2004) Article DOI: 10.1021/jm0310582 BindingDB Entry DOI: 10.7270/Q2Q81CHJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50409926 (CHEMBL2112314) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Effective concentration required for inhibition of Vitamin D3 receptor | J Med Chem 47: 1956-61 (2004) Article DOI: 10.1021/jm0310582 BindingDB Entry DOI: 10.7270/Q2Q81CHJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50015318 (CHEMBL3263871) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a |
Rikkyo University Curated by ChEMBL | Assay Description Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-N-CoR and 4-tk-LUC assessed as inhibition of N-CoR binding to VDR by mammali... | J Med Chem 57: 4073-87 (2014) Article DOI: 10.1021/jm401989c BindingDB Entry DOI: 10.7270/Q2ZS2Z2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50200182 ((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Agonist activity at human VDR in COS7 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase rep... | Bioorg Med Chem 16: 457-73 (2008) Article DOI: 10.1016/j.bmc.2007.09.017 BindingDB Entry DOI: 10.7270/Q2VD70BN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50015318 (CHEMBL3263871) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a |
Rikkyo University Curated by ChEMBL | Assay Description Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-NCoR2 and 4-tk-LUC assessed as inhibition of NCoR2 binding to VDR by mammali... | J Med Chem 57: 4073-87 (2014) Article DOI: 10.1021/jm401989c BindingDB Entry DOI: 10.7270/Q2ZS2Z2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50198705 ((2E)-(20R)-1alpha,25-dihydroxy-2-[(2''-hydroxyethy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Inhibition of human VDR induced-transcriptional transactivation of luciferase reporter gene in COS7 cells after 24 hrs | Bioorg Med Chem 15: 1475-82 (2007) Article DOI: 10.1016/j.bmc.2006.10.069 BindingDB Entry DOI: 10.7270/Q2TT4QK5 | |||||||||||
More data for this Ligand-Target Pair |
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