Compile Data Set for Download or QSAR

Found 6 hits of ec50 data for polymerid = 50005943   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine kinase 2-beta (Mus musculus)	BDBM50301356 (CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES CNc1ccn(-c2ccccc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cn1 Show InChI InChI=1S/C29H25N5O5/c1-30-21-12-14-34(18-7-5-4-6-8-18)29(36)27(21)28(35)33-26-10-9-19(17-32-26)39-23-11-13-31-22-16-25(38-3)24(37-2)15-20(22)23/h4-17,30H,1-3H3,(H,32,33,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in osteocalcin level				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Mus musculus)	BDBM50301356 (CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES CNc1ccn(-c2ccccc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cn1 Show InChI InChI=1S/C29H25N5O5/c1-30-21-12-14-34(18-7-5-4-6-8-18)29(36)27(21)28(35)33-26-10-9-19(17-32-26)39-23-11-13-31-22-16-25(38-3)24(37-2)15-20(22)23/h4-17,30H,1-3H3,(H,32,33,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in alkaline phosphatase level				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Mus musculus)	BDBM50301364 (CHEMBL570380 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)c4cc(cn(-c5ccccc5)c4=O)-c4cccs4)nc3)c2cc1OC Show InChI InChI=1S/C32H24N4O5S/c1-39-27-16-23-25(17-28(27)40-2)33-13-12-26(23)41-22-10-11-30(34-18-22)35-31(37)24-15-20(29-9-6-14-42-29)19-36(32(24)38)21-7-4-3-5-8-21/h3-19H,1-2H3,(H,34,35,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in alkaline phosphatase level				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Mus musculus)	BDBM50301364 (CHEMBL570380 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)c4cc(cn(-c5ccccc5)c4=O)-c4cccs4)nc3)c2cc1OC Show InChI InChI=1S/C32H24N4O5S/c1-39-27-16-23-25(17-28(27)40-2)33-13-12-26(23)41-22-10-11-30(34-18-22)35-31(37)24-15-20(29-9-6-14-42-29)19-36(32(24)38)21-7-4-3-5-8-21/h3-19H,1-2H3,(H,34,35,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in calcium level				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Mus musculus)	BDBM50301364 (CHEMBL570380 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)c4cc(cn(-c5ccccc5)c4=O)-c4cccs4)nc3)c2cc1OC Show InChI InChI=1S/C32H24N4O5S/c1-39-27-16-23-25(17-28(27)40-2)33-13-12-26(23)41-22-10-11-30(34-18-22)35-31(37)24-15-20(29-9-6-14-42-29)19-36(32(24)38)21-7-4-3-5-8-21/h3-19H,1-2H3,(H,34,35,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in osteocalcin level				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Mus musculus)	BDBM50301356 (CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES CNc1ccn(-c2ccccc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cn1 Show InChI InChI=1S/C29H25N5O5/c1-30-21-12-14-34(18-7-5-4-6-8-18)29(36)27(21)28(35)33-26-10-9-19(17-32-26)39-23-11-13-31-22-16-25(38-3)24(37-2)15-20(22)23/h4-17,30H,1-3H3,(H,32,33,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in calcium level				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair