Compile Data Set for Download or QSAR

Found 73 hits of ec50 data for polymerid = 50006042   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50594560 (CHEMBL5180843) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1ccc(OC(=O)CC23CC4CC(CC(C4)C2)C3)c(OC)c1)C(C)C)C(=O)OCC |r,THB:37:35:32:38.29.30,37:29:32:36.34.35,34:33:30:36.35.37,34:35:32.33.38:30| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.5	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00121 BindingDB Entry DOI: 10.7270/Q25B06HT
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50582642 (CHEMBL5070781) Show SMILES CCCCCCCCCCCC(=O)Oc1ccc(\C=C\C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@H](CCC(=O)OCC)C(=O)OCC)cc1OC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as increase in NFkappaB transactivation-mediated SEAP activity measured after 18 hrs by spe...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00644 BindingDB Entry DOI: 10.7270/Q2W66QN7
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50594558 (CHEMBL5187281) Show SMILES CC(C)[C@H](NC(=O)CNC(=O)\C=C\c1cccc(c1)-c1ccccc1)C(=O)N[C@H](CCC(=O)OC1CCCC1)C(=O)OC1CCCC1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00121 BindingDB Entry DOI: 10.7270/Q25B06HT
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50582634 (CHEMBL5077049) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H]1C[C@H]1c1ccc(F)c(F)c1)C(C)C)C(=O)OCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as increase in NFkappaB transactivation-mediated SEAP activity measured after 18 hrs by spe...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00644 BindingDB Entry DOI: 10.7270/Q2W66QN7
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50582640 (CHEMBL5079672) Show SMILES COc1cc(\C=C\C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@H](CCC(=O)OC2CCCC2)C(=O)OC2CCCC2)ccc1O |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as increase in NFkappaB transactivation-mediated SEAP activity measured after 18 hrs by spe...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00644 BindingDB Entry DOI: 10.7270/Q2W66QN7
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50594561 (CHEMBL5203244) Show SMILES COc1cc(\C=C\C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@H](CCC(=O)OC2CCCC2)C(=O)OC2CCCC2)ccc1OC(=O)CC12CC3CC(CC(C3)C1)C2 |r,THB:55:53:50:56.47.48,55:47:50:54.52.53,52:51:48:54.53.55,52:53:50.51.56:48| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	44	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00121 BindingDB Entry DOI: 10.7270/Q25B06HT
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50582640 (CHEMBL5079672) Show SMILES COc1cc(\C=C\C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@H](CCC(=O)OC2CCCC2)C(=O)OC2CCCC2)ccc1O |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00121 BindingDB Entry DOI: 10.7270/Q25B06HT
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50164885 (CHEBI:59414 | muramyldipeptide) Show SMILES C[C@H](NC(=O)[C@@H](C)O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](O)[C@@H]1NC(C)=O)C(=O)N[C@H](CCC(O)=O)C(N)=O |r| Show InChI InChI=1S/C19H32N4O11/c1-7(17(30)23-10(16(20)29)4-5-12(26)27)21-18(31)8(2)33-15-13(22-9(3)25)19(32)34-11(6-24)14(15)28/h7-8,10-11,13-15,19,24,28,32H,4-6H2,1-3H3,(H2,20,29)(H,21,31)(H,22,25)(H,23,30)(H,26,27)/t7-,8+,10+,11+,13+,14+,15+,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	46	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Agonist activity at NOD2 receptor (unknown origin) expressed in HEK-Blue cells assessed as NF-kappaB transcriptional activity after 18 hrs by secrete...				Eur J Med Chem 116: 1-12 (2016) Article DOI: 10.1016/j.ejmech.2016.03.030 BindingDB Entry DOI: 10.7270/Q2ZK5JJV
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50245040 (CHEMBL4090558) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1ccc(O)c(OC)c1)C(C)C)C(=O)OCC |r| Show InChI InChI=1S/C26H37N3O9/c1-6-37-23(33)13-10-18(26(35)38-7-2)28-25(34)24(16(3)4)29-22(32)15-27-21(31)12-9-17-8-11-19(30)20(14-17)36-5/h8-9,11-12,14,16,18,24,30H,6-7,10,13,15H2,1-5H3,(H,27,31)(H,28,34)(H,29,32)/b12-9+/t18-,24+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	46	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Agonist activity at human NOD2 expressed in HEK-Blue cells assessed as induction of NF-kB transcriptional activity after 18 hrs by SEAP reporter gene...				J Med Chem 61: 2707-2724 (2018) Article DOI: 10.1021/acs.jmedchem.7b01052 BindingDB Entry DOI: 10.7270/Q26M397P
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50594550 (CHEMBL5207301) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1cccc(c1)-c1ccccc1)C(C)C)C(=O)OCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	47	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00121 BindingDB Entry DOI: 10.7270/Q25B06HT
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50582630 (CHEMBL5086803) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1ccc(cc1)[N+]([O-])=O)C(C)C)C(=O)OCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	49	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as increase in NFkappaB transactivation-mediated SEAP activity measured after 18 hrs by spe...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00644 BindingDB Entry DOI: 10.7270/Q2W66QN7
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50245039 (CHEMBL4069541) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)C1CC1c1ccc(F)c(F)c1)C(C)C)C(=O)OCC |r| Show InChI InChI=1S/C26H35F2N3O7/c1-5-37-22(33)10-9-20(26(36)38-6-2)30-25(35)23(14(3)4)31-21(32)13-29-24(34)17-12-16(17)15-7-8-18(27)19(28)11-15/h7-8,11,14,16-17,20,23H,5-6,9-10,12-13H2,1-4H3,(H,29,34)(H,30,35)(H,31,32)/t16?,17?,20-,23+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	49	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as increase in NFkappaB transactivation-mediated SEAP activity measured after 18 hrs by spe...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00644 BindingDB Entry DOI: 10.7270/Q2W66QN7
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50594551 (CHEMBL5193116) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1cccc(Oc2ccccc2)c1)C(C)C)C(=O)OCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	61	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00121 BindingDB Entry DOI: 10.7270/Q25B06HT
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50582641 (CHEMBL5085864) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1ccc(OC(C)=O)c(OC)c1)C(C)C)C(=O)OCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	62	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as increase in NFkappaB transactivation-mediated SEAP activity measured after 18 hrs by spe...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00644 BindingDB Entry DOI: 10.7270/Q2W66QN7
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50582644 (CHEMBL5077437) Show SMILES COc1cc(\C=C\C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@H](CCC(=O)OC2CCCC2)C(=O)OC2CCCC2)ccc1OC(C)=O |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	63	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as increase in NFkappaB transactivation-mediated SEAP activity measured after 18 hrs by spe...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00644 BindingDB Entry DOI: 10.7270/Q2W66QN7
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50582633 (CHEMBL5075343) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@H]1C[C@@H]1c1ccc(F)c(F)c1)C(C)C)C(=O)OCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	66	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as increase in NFkappaB transactivation-mediated SEAP activity measured after 18 hrs by spe...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00644 BindingDB Entry DOI: 10.7270/Q2W66QN7
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50582629 (CHEMBL5090188) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1ccc(cc1)C(C)C)C(C)C)C(=O)OCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	71	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as increase in NFkappaB transactivation-mediated SEAP activity measured after 18 hrs by spe...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00644 BindingDB Entry DOI: 10.7270/Q2W66QN7
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50594548 (CHEMBL5192766) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1cccc(c1)[N+]([O-])=O)C(C)C)C(=O)OCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	82	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00121 BindingDB Entry DOI: 10.7270/Q25B06HT
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50245040 (CHEMBL4090558) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1ccc(O)c(OC)c1)C(C)C)C(=O)OCC |r| Show InChI InChI=1S/C26H37N3O9/c1-6-37-23(33)13-10-18(26(35)38-7-2)28-25(34)24(16(3)4)29-22(32)15-27-21(31)12-9-17-8-11-19(30)20(14-17)36-5/h8-9,11-12,14,16,18,24,30H,6-7,10,13,15H2,1-5H3,(H,27,31)(H,28,34)(H,29,32)/b12-9+/t18-,24+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	89	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as increase in NFkappaB transactivation-mediated SEAP activity measured after 18 hrs by spe...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00644 BindingDB Entry DOI: 10.7270/Q2W66QN7
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50164885 (CHEBI:59414 | muramyldipeptide) Show SMILES C[C@H](NC(=O)[C@@H](C)O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](O)[C@@H]1NC(C)=O)C(=O)N[C@H](CCC(O)=O)C(N)=O |r| Show InChI InChI=1S/C19H32N4O11/c1-7(17(30)23-10(16(20)29)4-5-12(26)27)21-18(31)8(2)33-15-13(22-9(3)25)19(32)34-11(6-24)14(15)28/h7-8,10-11,13-15,19,24,28,32H,4-6H2,1-3H3,(H2,20,29)(H,21,31)(H,22,25)(H,23,30)(H,26,27)/t7-,8+,10+,11+,13+,14+,15+,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	92	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Agonist activity at human NOD2 expressed in HEK-Blue cells assessed as induction of NF-kB transcriptional activity after 18 hrs by SEAP reporter gene...				J Med Chem 61: 2707-2724 (2018) Article DOI: 10.1021/acs.jmedchem.7b01052 BindingDB Entry DOI: 10.7270/Q26M397P
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50245040 (CHEMBL4090558) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1ccc(O)c(OC)c1)C(C)C)C(=O)OCC |r| Show InChI InChI=1S/C26H37N3O9/c1-6-37-23(33)13-10-18(26(35)38-7-2)28-25(34)24(16(3)4)29-22(32)15-27-21(31)12-9-17-8-11-19(30)20(14-17)36-5/h8-9,11-12,14,16,18,24,30H,6-7,10,13,15H2,1-5H3,(H,27,31)(H,28,34)(H,29,32)/b12-9+/t18-,24+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	99	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00808 BindingDB Entry DOI: 10.7270/Q2QC07HJ
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50588617 (CHEMBL5178827) Show SMILES CCCCOc1nc(N)c2nc(O)n(Cc3ccc(cc3)C(=O)NCCCCCC(=O)Oc3ccc(\C=C\C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@H](CCC(=O)OCC)C(=O)OCC)cc3OC)c2n1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	114	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00808 BindingDB Entry DOI: 10.7270/Q2QC07HJ
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50245097 (CHEMBL4060406) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)\C=C\c1ccc(O)c(OC)c1)C(=O)OCC |r| Show InChI InChI=1S/C30H37N3O9/c1-4-41-28(37)16-13-22(30(39)42-5-2)33-29(38)23(17-20-9-7-6-8-10-20)32-27(36)19-31-26(35)15-12-21-11-14-24(34)25(18-21)40-3/h6-12,14-15,18,22-23,34H,4-5,13,16-17,19H2,1-3H3,(H,31,35)(H,32,36)(H,33,38)/b15-12+/t22-,23+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	121	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Agonist activity at human NOD2 expressed in HEK-Blue cells assessed as induction of NF-kB transcriptional activity after 18 hrs by SEAP reporter gene...				J Med Chem 61: 2707-2724 (2018) Article DOI: 10.1021/acs.jmedchem.7b01052 BindingDB Entry DOI: 10.7270/Q26M397P
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50594559 (CHEMBL5184036) Show SMILES CC(C)[C@H](NC(=O)CNC(=O)\C=C\c1cccc(Oc2ccccc2)c1)C(=O)N[C@H](CCC(=O)OC1CCCC1)C(=O)OC1CCCC1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00121 BindingDB Entry DOI: 10.7270/Q25B06HT
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50594549 (CHEMBL5182728) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1cccc(Br)c1)C(C)C)C(=O)OCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	135	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00121 BindingDB Entry DOI: 10.7270/Q25B06HT
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50164885 (CHEBI:59414 | muramyldipeptide) Show SMILES C[C@H](NC(=O)[C@@H](C)O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](O)[C@@H]1NC(C)=O)C(=O)N[C@H](CCC(O)=O)C(N)=O |r| Show InChI InChI=1S/C19H32N4O11/c1-7(17(30)23-10(16(20)29)4-5-12(26)27)21-18(31)8(2)33-15-13(22-9(3)25)19(32)34-11(6-24)14(15)28/h7-8,10-11,13-15,19,24,28,32H,4-6H2,1-3H3,(H2,20,29)(H,21,31)(H,22,25)(H,23,30)(H,26,27)/t7-,8+,10+,11+,13+,14+,15+,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	148	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as increase in NFkappaB transactivation-mediated SEAP activity measured after 18 hrs by spe...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00644 BindingDB Entry DOI: 10.7270/Q2W66QN7
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50245074 (CHEMBL4094910) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)\C=C\c1ccc(F)c(F)c1)C(=O)OCC |r| Show InChI InChI=1S/C29H33F2N3O7/c1-3-40-27(37)15-13-23(29(39)41-4-2)34-28(38)24(17-19-8-6-5-7-9-19)33-26(36)18-32-25(35)14-11-20-10-12-21(30)22(31)16-20/h5-12,14,16,23-24H,3-4,13,15,17-18H2,1-2H3,(H,32,35)(H,33,36)(H,34,38)/b14-11+/t23-,24+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	172	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Agonist activity at human NOD2 expressed in HEK-Blue cells assessed as induction of NF-kB transcriptional activity after 18 hrs by SEAP reporter gene...				J Med Chem 61: 2707-2724 (2018) Article DOI: 10.1021/acs.jmedchem.7b01052 BindingDB Entry DOI: 10.7270/Q26M397P
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50245104 (CHEMBL4068530) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1ccc(F)c(F)c1)C(C)C)C(=O)OCC |r| Show InChI InChI=1S/C25H33F2N3O7/c1-5-36-22(33)12-10-19(25(35)37-6-2)29-24(34)23(15(3)4)30-21(32)14-28-20(31)11-8-16-7-9-17(26)18(27)13-16/h7-9,11,13,15,19,23H,5-6,10,12,14H2,1-4H3,(H,28,31)(H,29,34)(H,30,32)/b11-8+/t19-,23+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	172	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Agonist activity at human NOD2 expressed in HEK-Blue cells assessed as induction of NF-kB transcriptional activity after 18 hrs by SEAP reporter gene...				J Med Chem 61: 2707-2724 (2018) Article DOI: 10.1021/acs.jmedchem.7b01052 BindingDB Entry DOI: 10.7270/Q26M397P
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50245040 (CHEMBL4090558) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1ccc(O)c(OC)c1)C(C)C)C(=O)OCC |r| Show InChI InChI=1S/C26H37N3O9/c1-6-37-23(33)13-10-18(26(35)38-7-2)28-25(34)24(16(3)4)29-22(32)15-27-21(31)12-9-17-8-11-19(30)20(14-17)36-5/h8-9,11-12,14,16,18,24,30H,6-7,10,13,15H2,1-5H3,(H,27,31)(H,28,34)(H,29,32)/b12-9+/t18-,24+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	203	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00121 BindingDB Entry DOI: 10.7270/Q25B06HT
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50245038 (CHEMBL4059862) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1ccccc1)C(C)C)C(=O)OCC |r| Show InChI InChI=1S/C25H35N3O7/c1-5-34-22(31)15-13-19(25(33)35-6-2)27-24(32)23(17(3)4)28-21(30)16-26-20(29)14-12-18-10-8-7-9-11-18/h7-12,14,17,19,23H,5-6,13,15-16H2,1-4H3,(H,26,29)(H,27,32)(H,28,30)/b14-12+/t19-,23+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	223	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Binding affinity at [3H]QNB radiolabeled muscarinic M2 receptor in rat heart.				J Med Chem 61: 2707-2724 (2018) Article DOI: 10.1021/acs.jmedchem.7b01052 BindingDB Entry DOI: 10.7270/Q26M397P
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50582645 (CHEMBL5073412) Show SMILES CCCCCCCCCCCC(=O)Oc1ccc(\C=C\C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@H](CCC(=O)OC2CCCC2)C(=O)OC2CCCC2)cc1OC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	243	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as increase in NFkappaB transactivation-mediated SEAP activity measured after 18 hrs by spe...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00644 BindingDB Entry DOI: 10.7270/Q2W66QN7
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50245039 (CHEMBL4069541) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)C1CC1c1ccc(F)c(F)c1)C(C)C)C(=O)OCC |r| Show InChI InChI=1S/C26H35F2N3O7/c1-5-37-22(33)10-9-20(26(36)38-6-2)30-25(35)23(14(3)4)31-21(32)13-29-24(34)17-12-16(17)15-7-8-18(27)19(28)11-15/h7-8,11,14,16-17,20,23H,5-6,9-10,12-13H2,1-4H3,(H,29,34)(H,30,35)(H,31,32)/t16?,17?,20-,23+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	247	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Agonist activity at human NOD2 expressed in HEK-Blue cells assessed as induction of NF-kB transcriptional activity after 18 hrs by SEAP reporter gene...				J Med Chem 61: 2707-2724 (2018) Article DOI: 10.1021/acs.jmedchem.7b01052 BindingDB Entry DOI: 10.7270/Q26M397P
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50245075 (CHEMBL4088641) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)C1CC1c1ccc(F)c(F)c1)C(=O)OCC |r| Show InChI InChI=1S/C30H35F2N3O7/c1-3-41-27(37)13-12-24(30(40)42-4-2)35-29(39)25(14-18-8-6-5-7-9-18)34-26(36)17-33-28(38)21-16-20(21)19-10-11-22(31)23(32)15-19/h5-11,15,20-21,24-25H,3-4,12-14,16-17H2,1-2H3,(H,33,38)(H,34,36)(H,35,39)/t20?,21?,24-,25+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	276	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Agonist activity at human NOD2 expressed in HEK-Blue cells assessed as induction of NF-kB transcriptional activity after 18 hrs by SEAP reporter gene...				J Med Chem 61: 2707-2724 (2018) Article DOI: 10.1021/acs.jmedchem.7b01052 BindingDB Entry DOI: 10.7270/Q26M397P
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50594555 (CHEMBL5176249) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1cc2cc(Br)ccc2o1)C(C)C)C(=O)OCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00121 BindingDB Entry DOI: 10.7270/Q25B06HT
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50582631 (CHEMBL5079466) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)C1CC1c1ccc(OC)c(OC)c1)C(C)C)C(=O)OCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	322	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as increase in NFkappaB transactivation-mediated SEAP activity measured after 18 hrs by spe...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00644 BindingDB Entry DOI: 10.7270/Q2W66QN7
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50582632 (CHEMBL5079980) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)C1CC1c1ccc(O)c(OC)c1)C(C)C)C(=O)OCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	369	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as increase in NFkappaB transactivation-mediated SEAP activity measured after 18 hrs by spe...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00644 BindingDB Entry DOI: 10.7270/Q2W66QN7
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50245096 (CHEMBL4098290) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)\C=C\c1ccccc1)C(=O)OCC |r| Show InChI InChI=1S/C29H35N3O7/c1-3-38-27(35)18-16-23(29(37)39-4-2)32-28(36)24(19-22-13-9-6-10-14-22)31-26(34)20-30-25(33)17-15-21-11-7-5-8-12-21/h5-15,17,23-24H,3-4,16,18-20H2,1-2H3,(H,30,33)(H,31,34)(H,32,36)/b17-15+/t23-,24+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	388	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Agonist activity at human NOD2 expressed in HEK-Blue cells assessed as induction of NF-kB transcriptional activity after 18 hrs by SEAP reporter gene...				J Med Chem 61: 2707-2724 (2018) Article DOI: 10.1021/acs.jmedchem.7b01052 BindingDB Entry DOI: 10.7270/Q26M397P
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50594541 (CHEMBL5204917) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1ccc(C)cc1)C(C)C)C(=O)OCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	402	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00121 BindingDB Entry DOI: 10.7270/Q25B06HT
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50594543 (CHEMBL5186060) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1ccc(Cl)cc1)C(C)C)C(=O)OCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	412	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00121 BindingDB Entry DOI: 10.7270/Q25B06HT
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50594540 (CHEMBL5180997) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CNC(=O)\C=C\c1ccc(O)c(OC)c1)C(=O)OCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	420	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00121 BindingDB Entry DOI: 10.7270/Q25B06HT
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50245073 (CHEMBL4074427) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H]1C[C@H]1c1ccccc1)C(=O)OCC |r| Show InChI InChI=1S/C30H37N3O7/c1-3-39-27(35)16-15-24(30(38)40-4-2)33-29(37)25(17-20-11-7-5-8-12-20)32-26(34)19-31-28(36)23-18-22(23)21-13-9-6-10-14-21/h5-14,22-25H,3-4,15-19H2,1-2H3,(H,31,36)(H,32,34)(H,33,37)/t22-,23+,24+,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	472	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to dopamine transporter in rat striatal membranes.				J Med Chem 61: 2707-2724 (2018) Article DOI: 10.1021/acs.jmedchem.7b01052 BindingDB Entry DOI: 10.7270/Q26M397P
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50594544 (CHEMBL5176732) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1ccc(Br)cc1)C(C)C)C(=O)OCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	534	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00121 BindingDB Entry DOI: 10.7270/Q25B06HT
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50582628 (CHEMBL5082818) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1ccc(N)cc1)C(C)C)C(=O)OCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	542	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as increase in NFkappaB transactivation-mediated SEAP activity measured after 18 hrs by spe...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00644 BindingDB Entry DOI: 10.7270/Q2W66QN7
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50594556 (CHEMBL5184105) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1cc2cc(ccc2o1)[N+]([O-])=O)C(C)C)C(=O)OCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	760	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00121 BindingDB Entry DOI: 10.7270/Q25B06HT
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50582626 (CHEMBL5084692) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1ccc(OC)c(OC)c1)C(C)C)C(=O)OCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	763	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as increase in NFkappaB transactivation-mediated SEAP activity measured after 18 hrs by spe...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00644 BindingDB Entry DOI: 10.7270/Q2W66QN7
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50245041 (CHEMBL4080248) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1cc2ccc(cc2[nH]1)-c1ccccc1)C(=O)OCC |r| Show InChI InChI=1S/C35H38N4O7/c1-3-45-32(41)18-17-27(35(44)46-4-2)39-34(43)29(19-23-11-7-5-8-12-23)38-31(40)22-36-33(42)30-21-26-16-15-25(20-28(26)37-30)24-13-9-6-10-14-24/h5-16,20-21,27,29,37H,3-4,17-19,22H2,1-2H3,(H,36,42)(H,38,40)(H,39,43)/t27-,29+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	777	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Agonist activity at human NOD2 expressed in HEK-Blue cells assessed as induction of NF-kB transcriptional activity after 18 hrs by SEAP reporter gene...				J Med Chem 61: 2707-2724 (2018) Article DOI: 10.1021/acs.jmedchem.7b01052 BindingDB Entry DOI: 10.7270/Q26M397P
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50594545 (CHEMBL5208149) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1ccc(OC(C)C)cc1)C(C)C)C(=O)OCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	795	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00121 BindingDB Entry DOI: 10.7270/Q25B06HT
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50594537 (CHEMBL5178458) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)CNC(=O)\C=C\c1ccc(O)c(OC)c1)C(=O)OCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00121 BindingDB Entry DOI: 10.7270/Q25B06HT
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50594542 (CHEMBL5202454) Show SMILES CCOC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)\C=C\c1ccc(cc1)C(F)(F)F)C(C)C)C(=O)OCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.19E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00121 BindingDB Entry DOI: 10.7270/Q25B06HT
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50582647 (CHEMBL5087802) Show SMILES CCCCCCCCCCCCCCCCCC(=O)Oc1ccc(\C=C\C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@H](CCC(=O)OCC)C(=O)OCC)cc1OC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as increase in NFkappaB transactivation-mediated SEAP activity measured after 18 hrs by spe...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00644 BindingDB Entry DOI: 10.7270/Q2W66QN7
					More data for this Ligand-Target Pair

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