Compile Data Set for Download or QSAR

Found 103 hits of ec50 data for polymerid = 50006345   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205410 (CHEMBL3970245) Show SMILES O=C(Cn1nnc(c1-c1ccccc1)-c1ccncc1)Nc1ccc(cn1)-c1ccccc1 Show InChI InChI=1S/C26H20N6O/c33-24(29-23-12-11-22(17-28-23)19-7-3-1-4-8-19)18-32-26(21-9-5-2-6-10-21)25(30-31-32)20-13-15-27-16-14-20/h1-17H,18H2,(H,28,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0800	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205500 (CHEMBL3933984) Show SMILES Fc1cnccc1-c1nnn(CC(=O)Nc2ccc(cn2)-c2ccccc2)c1-c1ccccc1 Show InChI InChI=1S/C26H19FN6O/c27-22-16-28-14-13-21(22)25-26(19-9-5-2-6-10-19)33(32-31-25)17-24(34)30-23-12-11-20(15-29-23)18-7-3-1-4-8-18/h1-16H,17H2,(H,29,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.130	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205473 (CHEMBL3952126) Show SMILES Cc1cnccc1-c1nnn(CC(=O)Nc2ccc(cn2)-c2ccccc2)c1-c1ccccc1 Show InChI InChI=1S/C27H22N6O/c1-19-16-28-15-14-23(19)26-27(21-10-6-3-7-11-21)33(32-31-26)18-25(34)30-24-13-12-22(17-29-24)20-8-4-2-5-9-20/h2-17H,18H2,1H3,(H,29,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.140	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205493 (CHEMBL3952665) Show SMILES COc1ccc(cc1)-c1c(nnn1CC(=O)Nc1ccc(cn1)-c1ccccc1)-c1ccncc1 Show InChI InChI=1S/C27H22N6O2/c1-35-23-10-7-21(8-11-23)27-26(20-13-15-28-16-14-20)31-32-33(27)18-25(34)30-24-12-9-22(17-29-24)19-5-3-2-4-6-19/h2-17H,18H2,1H3,(H,29,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.180	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205479 (CHEMBL3925918) Show SMILES O=C(Cn1nnc(c1-c1ccccc1)-c1ccncc1)Nc1ccc(nc1)-c1ccccc1 Show InChI InChI=1S/C26H20N6O/c33-24(29-22-11-12-23(28-17-22)19-7-3-1-4-8-19)18-32-26(21-9-5-2-6-10-21)25(30-31-32)20-13-15-27-16-14-20/h1-17H,18H2,(H,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205491 (CHEMBL3899701) Show SMILES Fc1ccc(cc1)-c1c(nnn1CC(=O)Nc1ccc(cn1)-c1ccccc1)-c1ccncc1 Show InChI InChI=1S/C26H19FN6O/c27-22-9-6-20(7-10-22)26-25(19-12-14-28-15-13-19)31-32-33(26)17-24(34)30-23-11-8-21(16-29-23)18-4-2-1-3-5-18/h1-16H,17H2,(H,29,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205482 (CHEMBL3943764) Show SMILES O=C(Cn1nnc(c1-c1ccccc1)-c1ccncc1)Nc1ccc(cn1)-c1cccs1 Show InChI InChI=1S/C24H18N6OS/c31-22(27-21-9-8-19(15-26-21)20-7-4-14-32-20)16-30-24(18-5-2-1-3-6-18)23(28-29-30)17-10-12-25-13-11-17/h1-15H,16H2,(H,26,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.260	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428001 (CHEMBL2322627) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cn1)-c1cccs1 Show InChI InChI=1S/C23H18N4O2S3/c28-20(26-19-9-8-15(13-24-19)18-7-4-11-30-18)14-32-23-25-17-10-12-31-21(17)22(29)27(23)16-5-2-1-3-6-16/h1-9,11,13H,10,12,14H2,(H,24,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205483 (CHEMBL3935037) Show SMILES FC(F)(F)c1ccc(cc1)-c1c(nnn1CC(=O)Nc1ccc(cn1)-c1ccccc1)-c1ccncc1 Show InChI InChI=1S/C27H19F3N6O/c28-27(29,30)22-9-6-20(7-10-22)26-25(19-12-14-31-15-13-19)34-35-36(26)17-24(37)33-23-11-8-21(16-32-23)18-4-2-1-3-5-18/h1-16H,17H2,(H,32,33,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428009 (CHEMBL2323230) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(nc1)-c1ccccc1 Show InChI InChI=1S/C25H20N4O2S2/c30-22(27-18-11-12-20(26-15-18)17-7-3-1-4-8-17)16-33-25-28-21-13-14-32-23(21)24(31)29(25)19-9-5-2-6-10-19/h1-12,15H,13-14,16H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205471 (CHEMBL3927718) Show SMILES Cc1cccc(c1)-c1c(nnn1CC(=O)Nc1ccc(cn1)-c1ccccc1)-c1ccncc1 Show InChI InChI=1S/C27H22N6O/c1-19-6-5-9-22(16-19)27-26(21-12-14-28-15-13-21)31-32-33(27)18-25(34)30-24-11-10-23(17-29-24)20-7-3-2-4-8-20/h2-17H,18H2,1H3,(H,29,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205481 (CHEMBL3952501) Show SMILES O=C(Cn1nnc(c1-c1ccccc1)-c1ccncc1)Nc1ccc(cn1)-c1ccco1 Show InChI InChI=1S/C24H18N6O2/c31-22(27-21-9-8-19(15-26-21)20-7-4-14-32-20)16-30-24(18-5-2-1-3-6-18)23(28-29-30)17-10-12-25-13-11-17/h1-15H,16H2,(H,26,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205474 (CHEMBL3892208) Show SMILES O=C(Cn1nnc(c1-c1ccccc1)-c1ccncc1)Nc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C27H21N5O/c33-25(29-24-13-11-21(12-14-24)20-7-3-1-4-8-20)19-32-27(23-9-5-2-6-10-23)26(30-31-32)22-15-17-28-18-16-22/h1-18H,19H2,(H,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.430	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428011 (CHEMBL2323228) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cc1)-c1cccnc1 Show InChI InChI=1S/C25H20N4O2S2/c30-22(27-19-10-8-17(9-11-19)18-5-4-13-26-15-18)16-33-25-28-21-12-14-32-23(21)24(31)29(25)20-6-2-1-3-7-20/h1-11,13,15H,12,14,16H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.450	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205469 (CHEMBL3897216) Show SMILES O=C(Cn1nnc(c1-c1ccc(cc1)C#N)-c1ccncc1)Nc1ccc(cn1)-c1ccccc1 Show InChI InChI=1S/C27H19N7O/c28-16-19-6-8-22(9-7-19)27-26(21-12-14-29-15-13-21)32-33-34(27)18-25(35)31-24-11-10-23(17-30-24)20-4-2-1-3-5-20/h1-15,17H,18H2,(H,30,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.480	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428008 (CHEMBL2323231) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cn1)-c1ccccc1 Show InChI InChI=1S/C25H20N4O2S2/c30-22(28-21-12-11-18(15-26-21)17-7-3-1-4-8-17)16-33-25-27-20-13-14-32-23(20)24(31)29(25)19-9-5-2-6-10-19/h1-12,15H,13-14,16H2,(H,26,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205558 (CHEMBL3953544) Show SMILES O=C(Cn1nnc(c1-c1ccccc1)-c1ccncc1)Nc1ccc(cn1)-c1ccoc1 Show InChI InChI=1S/C24H18N6O2/c31-22(27-21-7-6-19(14-26-21)20-10-13-32-16-20)15-30-24(18-4-2-1-3-5-18)23(28-29-30)17-8-11-25-12-9-17/h1-14,16H,15H2,(H,26,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205496 (CHEMBL3980962) Show SMILES FC(F)(F)c1cc(ccn1)-c1nnn(CC(=O)Nc2ccc(cn2)-c2ccccc2)c1-c1ccccc1 Show InChI InChI=1S/C27H19F3N6O/c28-27(29,30)22-15-20(13-14-31-22)25-26(19-9-5-2-6-10-19)36(35-34-25)17-24(37)33-23-12-11-21(16-32-23)18-7-3-1-4-8-18/h1-16H,17H2,(H,32,33,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205498 (CHEMBL3981277) Show SMILES O=C(Cn1nnc(c1-c1ccccc1)-c1ccncc1)Nc1ccc(cn1)-c1ccsc1 Show InChI InChI=1S/C24H18N6OS/c31-22(27-21-7-6-19(14-26-21)20-10-13-32-16-20)15-30-24(18-4-2-1-3-5-18)23(28-29-30)17-8-11-25-12-9-17/h1-14,16H,15H2,(H,26,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.650	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205497 (CHEMBL3907204) Show SMILES CCOC(=O)c1ccc(cc1)-c1c(nnn1CC(=O)Nc1ccc(cn1)-c1ccccc1)-c1ccncc1 Show InChI InChI=1S/C29H24N6O3/c1-2-38-29(37)23-10-8-22(9-11-23)28-27(21-14-16-30-17-15-21)33-34-35(28)19-26(36)32-25-13-12-24(18-31-25)20-6-4-3-5-7-20/h3-18H,2,19H2,1H3,(H,31,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.700	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428015 (CHEMBL2322632) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C26H21N3O2S2/c30-23(27-20-13-11-19(12-14-20)18-7-3-1-4-8-18)17-33-26-28-22-15-16-32-24(22)25(31)29(26)21-9-5-2-6-10-21/h1-14H,15-17H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.75	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428006 (CHEMBL2323233) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cn1)-c1cccnc1 Show InChI InChI=1S/C24H19N5O2S2/c30-21(28-20-9-8-17(14-26-20)16-5-4-11-25-13-16)15-33-24-27-19-10-12-32-22(19)23(31)29(24)18-6-2-1-3-7-18/h1-9,11,13-14H,10,12,15H2,(H,26,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428000 (CHEMBL2322628) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ncc(cn1)-c1ccoc1 Show InChI InChI=1S/C22H17N5O3S2/c28-18(26-21-23-10-15(11-24-21)14-6-8-30-12-14)13-32-22-25-17-7-9-31-19(17)20(29)27(22)16-4-2-1-3-5-16/h1-6,8,10-12H,7,9,13H2,(H,23,24,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428004 (CHEMBL2322624) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cn1)-c1ccoc1 Show InChI InChI=1S/C23H18N4O3S2/c28-20(26-19-7-6-15(12-24-19)16-8-10-30-13-16)14-32-23-25-18-9-11-31-21(18)22(29)27(23)17-4-2-1-3-5-17/h1-8,10,12-13H,9,11,14H2,(H,24,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205489 (CHEMBL3943114) Show SMILES O=C(Cn1nnc(c1-c1ccccc1)-c1ccncc1)Nc1ccc(cc1)-c1ccccn1 Show InChI InChI=1S/C26H20N6O/c33-24(29-22-11-9-19(10-12-22)23-8-4-5-15-28-23)18-32-26(21-6-2-1-3-7-21)25(30-31-32)20-13-16-27-17-14-20/h1-17H,18H2,(H,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205495 (CHEMBL3905849) Show SMILES O=C(Cn1nnc(c1-c1ccccc1)-c1ccncc1)Nc1ccc(cn1)-c1cncnc1 Show InChI InChI=1S/C24H18N8O/c33-22(29-21-7-6-19(14-28-21)20-12-26-16-27-13-20)15-32-24(18-4-2-1-3-5-18)23(30-31-32)17-8-10-25-11-9-17/h1-14,16H,15H2,(H,28,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428002 (CHEMBL2322626) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cn1)-c1ccsc1 Show InChI InChI=1S/C23H18N4O2S3/c28-20(26-19-7-6-15(12-24-19)16-8-10-30-13-16)14-32-23-25-18-9-11-31-21(18)22(29)27(23)17-4-2-1-3-5-17/h1-8,10,12-13H,9,11,14H2,(H,24,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205562 (CHEMBL3893457) Show SMILES CC(C(=O)Nc1ccc(cn1)-c1ccccc1)n1nnc(c1-c1ccccc1)-c1ccncc1 Show InChI InChI=1S/C27H22N6O/c1-19(27(34)30-24-13-12-23(18-29-24)20-8-4-2-5-9-20)33-26(22-10-6-3-7-11-22)25(31-32-33)21-14-16-28-17-15-21/h2-19H,1H3,(H,29,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428010 (CHEMBL2323229) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C25H20N4O2S2/c30-22(27-19-8-6-17(7-9-19)18-10-13-26-14-11-18)16-33-25-28-21-12-15-32-23(21)24(31)29(25)20-4-2-1-3-5-20/h1-11,13-14H,12,15-16H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428003 (CHEMBL2322625) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cn1)-c1ccco1 Show InChI InChI=1S/C23H18N4O3S2/c28-20(26-19-9-8-15(13-24-19)18-7-4-11-30-18)14-32-23-25-17-10-12-31-21(17)22(29)27(23)16-5-2-1-3-6-16/h1-9,11,13H,10,12,14H2,(H,24,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.5	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50427999 (CHEMBL2322629) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ncc(cn1)-c1ccco1 Show InChI InChI=1S/C22H17N5O3S2/c28-18(26-21-23-11-14(12-24-21)17-7-4-9-30-17)13-32-22-25-16-8-10-31-19(16)20(29)27(22)15-5-2-1-3-6-15/h1-7,9,11-12H,8,10,13H2,(H,23,24,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.5	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428012 (CHEMBL2322635) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cc1)-c1ccccn1 Show InChI InChI=1S/C25H20N4O2S2/c30-22(27-18-11-9-17(10-12-18)20-8-4-5-14-26-20)16-33-25-28-21-13-15-32-23(21)24(31)29(25)19-6-2-1-3-7-19/h1-12,14H,13,15-16H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205487 (CHEMBL3947115) Show SMILES O=C(Cn1nnc(c1-c1ccccc1)-c1cccnc1)Nc1ccc(cn1)-c1ccccc1 Show InChI InChI=1S/C26H20N6O/c33-24(29-23-14-13-21(17-28-23)19-8-3-1-4-9-19)18-32-26(20-10-5-2-6-11-20)25(30-31-32)22-12-7-15-27-16-22/h1-17H,18H2,(H,28,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428005 (CHEMBL2322623) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cn1)-c1cncnc1 Show InChI InChI=1S/C23H18N6O2S2/c30-20(28-19-7-6-15(12-26-19)16-10-24-14-25-11-16)13-33-23-27-18-8-9-32-21(18)22(31)29(23)17-4-2-1-3-5-17/h1-7,10-12,14H,8-9,13H2,(H,26,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.5	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205470 (CHEMBL3968025) Show SMILES O=C(Cn1nnc(c1-c1cccc2ccccc12)-c1ccncc1)Nc1ccc(cn1)-c1ccccc1 |(26.49,-4.07,;26.51,-5.61,;25.18,-6.4,;23.72,-5.93,;23.24,-4.46,;21.7,-4.46,;21.23,-5.92,;22.47,-6.83,;22.46,-8.36,;21.12,-9.13,;21.12,-10.67,;22.45,-11.44,;23.79,-10.67,;25.11,-11.43,;26.44,-10.67,;26.44,-9.13,;25.11,-8.37,;23.79,-9.13,;19.76,-6.4,;19.44,-7.9,;17.97,-8.38,;16.83,-7.35,;17.16,-5.84,;18.62,-5.37,;27.85,-6.37,;29.17,-5.58,;30.52,-6.33,;31.84,-5.55,;31.82,-4,;30.48,-3.26,;29.15,-4.04,;33.15,-3.22,;34.49,-3.97,;35.81,-3.18,;35.79,-1.65,;34.45,-.89,;33.13,-1.68,)| Show InChI InChI=1S/C30H22N6O/c37-28(33-27-14-13-24(19-32-27)21-7-2-1-3-8-21)20-36-30(29(34-35-36)23-15-17-31-18-16-23)26-12-6-10-22-9-4-5-11-25(22)26/h1-19H,20H2,(H,32,33,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.5	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205503 (CHEMBL3954145) Show SMILES O=C(Cn1nnc(c1-c1ccccc1)-c1ccncc1)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C26H20N6O/c33-24(29-23-8-6-19(7-9-23)20-10-14-27-15-11-20)18-32-26(22-4-2-1-3-5-22)25(30-31-32)21-12-16-28-17-13-21/h1-17H,18H2,(H,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205501 (CHEMBL3972297) Show SMILES O=C(Cn1nnc(c1-c1ccccc1)-c1ccncc1)Nc1ccc(cc1)N1CCCCC1 Show InChI InChI=1S/C26H26N6O/c33-24(28-22-9-11-23(12-10-22)31-17-5-2-6-18-31)19-32-26(21-7-3-1-4-8-21)25(29-30-32)20-13-15-27-16-14-20/h1,3-4,7-16H,2,5-6,17-19H2,(H,28,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205476 (CHEMBL3982830) Show SMILES O=C(Cn1nnc(c1-c1ccccc1)-c1ccncc1)Nc1ncc(cn1)-c1ccccc1 Show InChI InChI=1S/C25H19N7O/c33-22(29-25-27-15-21(16-28-25)18-7-3-1-4-8-18)17-32-24(20-9-5-2-6-10-20)23(30-31-32)19-11-13-26-14-12-19/h1-16H,17H2,(H,27,28,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205480 (CHEMBL3936691) Show SMILES COc1ccccc1-c1c(nnn1CC(=O)Nc1ccc(cn1)-c1ccccc1)-c1ccncc1 |(9.1,-6.3,;9.1,-7.84,;7.77,-8.62,;7.77,-10.15,;6.43,-10.93,;5.1,-10.15,;5.1,-8.61,;6.44,-7.85,;6.45,-6.32,;5.21,-5.41,;5.68,-3.95,;7.22,-3.95,;7.7,-5.41,;9.16,-5.89,;10.49,-5.1,;10.46,-3.56,;11.83,-5.86,;13.15,-5.07,;14.5,-5.82,;15.82,-5.04,;15.8,-3.49,;14.46,-2.74,;13.13,-3.53,;17.13,-2.7,;18.47,-3.46,;19.79,-2.67,;19.77,-1.13,;18.43,-.38,;17.1,-1.16,;3.74,-5.89,;3.42,-7.39,;1.95,-7.87,;.81,-6.83,;1.14,-5.33,;2.6,-4.85,)| Show InChI InChI=1S/C27H22N6O2/c1-35-23-10-6-5-9-22(23)27-26(20-13-15-28-16-14-20)31-32-33(27)18-25(34)30-24-12-11-21(17-29-24)19-7-3-2-4-8-19/h2-17H,18H2,1H3,(H,29,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205485 (CHEMBL3926685) Show SMILES O=C(Cn1cc(nn1)-c1ccncc1)Nc1ccc(cn1)-c1ccccc1 Show InChI InChI=1S/C20H16N6O/c27-20(14-26-13-18(24-25-26)16-8-10-21-11-9-16)23-19-7-6-17(12-22-19)15-4-2-1-3-5-15/h1-13H,14H2,(H,22,23,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205445 (CHEMBL3959152) Show SMILES CCC(C(=O)Nc1ccc(cn1)-c1ccccc1)n1nnc(c1-c1ccccc1)-c1ccncc1 Show InChI InChI=1S/C28H24N6O/c1-2-24(28(35)31-25-14-13-23(19-30-25)20-9-5-3-6-10-20)34-27(22-11-7-4-8-12-22)26(32-33-34)21-15-17-29-18-16-21/h3-19,24H,2H2,1H3,(H,30,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM37088 (2-[(3,6-dimethyl-4-oxidanylidene-6,7-dihydrothieno...) Show SMILES CC1Cc2nc(SCC(=O)Nc3nc4ccc(C)cc4s3)n(C)c(=O)c2S1 Show InChI InChI=1S/C18H18N4O2S3/c1-9-4-5-11-13(6-9)27-17(19-11)21-14(23)8-25-18-20-12-7-10(2)26-15(12)16(24)22(18)3/h4-6,10H,7-8H2,1-3H3,(H,19,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428007 (CHEMBL2323232) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ncc(cn1)-c1ccccc1 Show InChI InChI=1S/C24H19N5O2S2/c30-20(28-23-25-13-17(14-26-23)16-7-3-1-4-8-16)15-33-24-27-19-11-12-32-21(19)22(31)29(24)18-9-5-2-6-10-18/h1-10,13-14H,11-12,15H2,(H,25,26,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428042 (CHEMBL2324275) Show SMILES COc1ccc(cc1)-n1nc(C(=O)NCC(=O)Nc2nc3ccc(Cl)cc3s2)c2ccccc2c1=O Show InChI InChI=1S/C25H18ClN5O4S/c1-35-16-9-7-15(8-10-16)31-24(34)18-5-3-2-4-17(18)22(30-31)23(33)27-13-21(32)29-25-28-19-11-6-14(26)12-20(19)36-25/h2-12H,13H2,1H3,(H,27,33)(H,28,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205502 (CHEMBL3908085) Show SMILES COc1ccc(cc1)-c1nnn(CC(=O)Nc2ccc(cn2)-c2ccccc2)c1-c1ccccc1 Show InChI InChI=1S/C28H23N5O2/c1-35-24-15-12-21(13-16-24)27-28(22-10-6-3-7-11-22)33(32-31-27)19-26(34)30-25-17-14-23(18-29-25)20-8-4-2-5-9-20/h2-18H,19H2,1H3,(H,29,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428027 (CHEMBL1257090) Show SMILES COc1ccccc1-n1c(SCC(=O)Nc2nc3ccc(C)cc3s2)nc2CCSc2c1=O |(3.46,-37.28,;2.64,-35.97,;3.36,-34.61,;4.9,-34.56,;5.62,-33.19,;4.79,-31.89,;3.26,-31.95,;2.54,-33.31,;1.01,-33.36,;.18,-32.06,;.9,-30.7,;2.44,-30.65,;3.16,-29.28,;4.7,-29.23,;2.34,-27.98,;.8,-28.04,;-.15,-26.82,;-1.59,-27.36,;-2.95,-26.64,;-4.25,-27.46,;-4.19,-29,;-5.49,-29.82,;-2.83,-29.71,;-1.54,-28.9,;-.06,-29.32,;-1.36,-32.12,;-2.08,-33.46,;-3.58,-33.83,;-3.7,-35.38,;-2.26,-35.96,;-1.26,-34.78,;.28,-34.72,;1.09,-36.03,)| Show InChI InChI=1S/C23H20N4O3S3/c1-13-7-8-14-18(11-13)33-22(24-14)26-19(28)12-32-23-25-15-9-10-31-20(15)21(29)27(23)16-5-3-4-6-17(16)30-2/h3-8,11H,9-10,12H2,1-2H3,(H,24,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428043 (CHEMBL2324274) Show SMILES Fc1ccc(cc1)-n1nc(C(=O)NCC(=O)Nc2nc3ccc(Cl)cc3s2)c2ccccc2c1=O Show InChI InChI=1S/C24H15ClFN5O3S/c25-13-5-10-18-19(11-13)35-24(28-18)29-20(32)12-27-22(33)21-16-3-1-2-4-17(16)23(34)31(30-21)15-8-6-14(26)7-9-15/h1-11H,12H2,(H,27,33)(H,28,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428050 (CHEMBL2322622) Show SMILES COc1ccc(cc1)-n1nc(C(=O)NCC(=O)Nc2nc3ccc(C)cc3s2)c2ccccc2c1=O Show InChI InChI=1S/C26H21N5O4S/c1-15-7-12-20-21(13-15)36-26(28-20)29-22(32)14-27-24(33)23-18-5-3-4-6-19(18)25(34)31(30-23)16-8-10-17(35-2)11-9-16/h3-13H,14H2,1-2H3,(H,27,33)(H,28,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428033 (CHEMBL2325505) Show SMILES COc1ccccc1-n1c(SCC(=O)Nc2nc3ccc(cc3s2)C(F)(F)F)nc2CCSc2c1=O |(46.71,-19.26,;45.38,-20.03,;45.39,-21.58,;46.72,-22.34,;46.73,-23.89,;45.4,-24.66,;44.06,-23.89,;44.06,-22.35,;42.73,-21.58,;42.73,-20.03,;44.06,-19.25,;44.05,-17.71,;45.39,-16.94,;45.38,-15.4,;46.72,-17.7,;48.05,-16.93,;49.46,-17.55,;50.48,-16.4,;52.02,-16.4,;52.78,-15.06,;52,-13.73,;50.47,-13.74,;49.71,-15.07,;48.2,-15.39,;52.76,-12.39,;54.3,-12.38,;51.98,-11.06,;53.52,-11.05,;41.39,-19.26,;40.05,-20.04,;38.59,-19.57,;37.69,-20.82,;38.6,-22.06,;40.06,-21.58,;41.39,-22.35,;41.39,-23.89,)| Show InChI InChI=1S/C23H17F3N4O3S3/c1-33-16-5-3-2-4-15(16)30-20(32)19-14(8-9-34-19)28-22(30)35-11-18(31)29-21-27-13-7-6-12(23(24,25)26)10-17(13)36-21/h2-7,10H,8-9,11H2,1H3,(H,27,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50428016 (CHEMBL2323243) Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cc1)N1CCCCC1 Show InChI InChI=1S/C25H26N4O2S2/c30-22(26-18-9-11-19(12-10-18)28-14-5-2-6-15-28)17-33-25-27-21-13-16-32-23(21)24(31)29(25)20-7-3-1-4-8-20/h1,3-4,7-12H,2,5-6,13-17H2,(H,26,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay				J Med Chem 56: 2700-4 (2013) Article DOI: 10.1021/jm400159c BindingDB Entry DOI: 10.7270/Q2TD9ZP5
					More data for this Ligand-Target Pair

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