Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50012295 (CHEMBL217378 | ISHKDMQLGR | Ile-Ser-His-Lys-Asp-Me...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Abilitiy to induce shape change (polarization) in human polymorphonuclear leukocytes (PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50587360 (CHEMBL5082686) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 min... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01174 BindingDB Entry DOI: 10.7270/Q2WS8Z5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50587361 (CHEMBL5092578) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 min... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01174 BindingDB Entry DOI: 10.7270/Q2WS8Z5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50587348 (CHEMBL5093227) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 min... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01174 BindingDB Entry DOI: 10.7270/Q2WS8Z5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50587342 (CHEMBL5075364) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 5.80 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 min... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01174 BindingDB Entry DOI: 10.7270/Q2WS8Z5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50587359 (CHEMBL5087237) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 6.60 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 min... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01174 BindingDB Entry DOI: 10.7270/Q2WS8Z5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50587351 (CHEMBL5080234) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 min... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01174 BindingDB Entry DOI: 10.7270/Q2WS8Z5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50012295 (CHEMBL217378 | ISHKDMQLGR | Ile-Ser-His-Lys-Asp-Me...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Release of beta-glucuronidase from human polymorphonuclear leukocytes(PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50587346 (CHEMBL5085196) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 19 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 min... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01174 BindingDB Entry DOI: 10.7270/Q2WS8Z5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50587350 (CHEMBL5076900) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 24 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 min... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01174 BindingDB Entry DOI: 10.7270/Q2WS8Z5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50587362 (CHEMBL5092461) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 34 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 min... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01174 BindingDB Entry DOI: 10.7270/Q2WS8Z5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50587343 (CHEMBL5080181) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 39 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 min... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01174 BindingDB Entry DOI: 10.7270/Q2WS8Z5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50587347 (CHEMBL5081621) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 44 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 min... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01174 BindingDB Entry DOI: 10.7270/Q2WS8Z5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50587341 (CHEMBL5071478) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 58 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 min... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01174 BindingDB Entry DOI: 10.7270/Q2WS8Z5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50587358 (CHEMBL5085743) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 73 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 min... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01174 BindingDB Entry DOI: 10.7270/Q2WS8Z5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50587353 (CHEMBL5075511) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 92 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 min... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01174 BindingDB Entry DOI: 10.7270/Q2WS8Z5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50413240 (CHEMBL471412) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 123 | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Antagonist activity at human recombinant C5a receptor expressed in HEK cells assessed as inhibition of C5a-induced [35S]GTPgammaS binding | Bioorg Med Chem Lett 19: 1143-7 (2009) Article DOI: 10.1016/j.bmcl.2008.12.104 BindingDB Entry DOI: 10.7270/Q2Q241G1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50587349 (CHEMBL5078171) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 126 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 min... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01174 BindingDB Entry DOI: 10.7270/Q2WS8Z5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50033567 (CHEMBL408796 | Tyr-Ser-Phe-Lys-Gly-Leu-Leu-Leu-Gly...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Abilitiy to induce shape change (polarization) in human polymorphonuclear leukocytes (PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50587357 (CHEMBL5080381) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 360 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 min... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01174 BindingDB Entry DOI: 10.7270/Q2WS8Z5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50587353 (CHEMBL5075511) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 590 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at C5aR1 in human MDM cells assessed as induction of intracellular calcium mobilization pretreated with antagonist PMX53 for 30 mins... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01174 BindingDB Entry DOI: 10.7270/Q2WS8Z5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50587345 (CHEMBL5092449) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 708 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 min... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01174 BindingDB Entry DOI: 10.7270/Q2WS8Z5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50587352 (CHEMBL5079833) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 895 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 min... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01174 BindingDB Entry DOI: 10.7270/Q2WS8Z5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50008381 (CHEMBL441393 | H-Ile-Ser-Phe-Lys-AspMet-GIn-Leu-Gl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 900 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Abilitiy to induce shape change (polarization) in human polymorphonuclear leukocytes (PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50033570 (CHEMBL265884 | Tyr-Ser-Phe-Lys-Asp-Met-Gln-Leu-D-A...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Abilitiy to induce shape change (polarization) in human polymorphonuclear leukocytes (PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50587354 (CHEMBL5083558) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.43E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 min... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01174 BindingDB Entry DOI: 10.7270/Q2WS8Z5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50033577 (CHEMBL269480 | Tyr-Ser-Phe-Lys-Gly-Met-Pro-Leu-Gly...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Abilitiy to induce shape change (polarization) in human polymorphonuclear leukocytes (PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50033563 (CHEMBL429535 | Tyr-Ser-Phe-Lys-Asp-Met-Pro-Leu-D-A...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Abilitiy to induce shape change (polarization) in human polymorphonuclear leukocytes (PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50033573 (CHEMBL268322 | Tyr-Ser-Phe-Lys-Asp-Ala-Pro-Leu-Ala...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Abilitiy to induce shape change (polarization) in human polymorphonuclear leukocytes (PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50033558 (CHEMBL414361 | Tyr-Ser-Phe-Lys-Asp-Met-Pro-Leu-Pro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Abilitiy to induce shape change (polarization) in human polymorphonuclear leukocytes (PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50033561 (CHEMBL438728 | Tyr-Ser-Phe-Lys-Asp-Met-Pro-Leu-Phe...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Abilitiy to induce shape change (polarization) in human polymorphonuclear leukocytes (PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50587355 (CHEMBL5087896) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 4.57E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 min... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01174 BindingDB Entry DOI: 10.7270/Q2WS8Z5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50033559 (CHEMBL435318 | Tyr-Ser-Phe-Lys-Asp-Met-Pro-Leu-Gly...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Abilitiy to induce shape change (polarization) in human polymorphonuclear leukocytes (PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50033560 (CHEMBL412249 | Tyr-Ser-Phe-Lys-Asp-Met-Pro-Ala-D-A...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Abilitiy to induce shape change (polarization) in human polymorphonuclear leukocytes (PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50033566 (CHEMBL427936 | Tyr-Ser-Phe-Lys-Asp-Ala-Pro-Leu-Gly...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 1.58E+4 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Abilitiy to induce shape change (polarization) in human polymorphonuclear leukocytes (PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50587344 (CHEMBL5081287) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.91E+4 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 min... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01174 BindingDB Entry DOI: 10.7270/Q2WS8Z5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50033565 (CHEMBL262653 | Tyr-Ser-Phe-Lys-Asp-Cys-Pro-Leu-Gly...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 1.95E+4 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Abilitiy to induce shape change (polarization) in human polymorphonuclear leukocytes (PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50033575 (CHEMBL412680 | Tyr-Ser-Phe-Lys-Asp-Met-Gln-Pro-Gly...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Abilitiy to induce shape change (polarization) in human polymorphonuclear leukocytes (PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50033567 (CHEMBL408796 | Tyr-Ser-Phe-Lys-Gly-Leu-Leu-Leu-Gly...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 2.77E+4 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Release of beta-glucuronidase from human polymorphonuclear leukocytes(PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50033570 (CHEMBL265884 | Tyr-Ser-Phe-Lys-Asp-Met-Gln-Leu-D-A...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Release of beta-glucuronidase from human polymorphonuclear leukocytes(PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50033562 (CHEMBL406011 | Tyr-Ser-Phe-LyS-Asp-Met-Glu-Leu-Gly...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 3.70E+4 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Abilitiy to induce shape change (polarization) in human polymorphonuclear leukocytes (PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50033575 (CHEMBL412680 | Tyr-Ser-Phe-Lys-Asp-Met-Gln-Pro-Gly...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 4.20E+4 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Release of beta-glucuronidase from human polymorphonuclear leukocytes(PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50033558 (CHEMBL414361 | Tyr-Ser-Phe-Lys-Asp-Met-Pro-Leu-Pro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 4.65E+4 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Release of beta-glucuronidase from human polymorphonuclear leukocytes(PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50033568 (CHEMBL386427 | Tyr-Ser-Phe-Lys-Asp-Met-Gln-Leu-Ala...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 4.80E+4 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Abilitiy to induce shape change (polarization) in human polymorphonuclear leukocytes (PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50033577 (CHEMBL269480 | Tyr-Ser-Phe-Lys-Gly-Met-Pro-Leu-Gly...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 4.96E+4 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Release of beta-glucuronidase from human polymorphonuclear leukocytes(PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50033576 (CHEMBL405966 | Tyr-Ser-Phe-Lys-Asp-Met-Pro-Pro-Gly...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Abilitiy to induce shape change (polarization) in human polymorphonuclear leukocytes (PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50033563 (CHEMBL429535 | Tyr-Ser-Phe-Lys-Asp-Met-Pro-Leu-D-A...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 5.77E+4 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Release of beta-glucuronidase from human polymorphonuclear leukocytes(PMN) | J Med Chem 38: 3669-75 (1995) BindingDB Entry DOI: 10.7270/Q23777RC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50305736 (CHEMBL593033 | N,N'-(1,2-phenylene)bis(N-methylben...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >6.00E+4 | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Agonist activity at human C5a receptor expressed in CHO cells co-expressed with Galpha16 assessed as effect on anaphylatoxin C5a-induced intracellula... | Bioorg Med Chem Lett 20: 662-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.058 BindingDB Entry DOI: 10.7270/Q2B8586C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50305735 (CHEMBL595990 | N,N'-(1,2-phenylene)bis(N-methyl-1-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >6.00E+4 | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Agonist activity at human C5a receptor expressed in CHO cells co-expressed with Galpha16 assessed as effect on anaphylatoxin C5a-induced intracellula... | Bioorg Med Chem Lett 20: 662-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.058 BindingDB Entry DOI: 10.7270/Q2B8586C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50305737 (CHEMBL604277 | N,N'-(1,2-phenylene)bis(N-allyl-4-m...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >6.00E+4 | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Agonist activity at human C5a receptor expressed in CHO cells co-expressed with Galpha16 assessed as effect on anaphylatoxin C5a-induced intracellula... | Bioorg Med Chem Lett 20: 662-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.058 BindingDB Entry DOI: 10.7270/Q2B8586C | |||||||||||
More data for this Ligand-Target Pair |
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