Compile Data Set for Download or QSAR

Found 338 hits of ec50 data for polymerid = 7258   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327667 (CHEMBL1084637 | Dibenzo[b,f][1,4]oxazepine-4-carbo...) Show SMILES COC(=O)c1cccc2C=Nc3ccccc3Oc12 |c:9| Show InChI InChI=1S/C15H11NO3/c1-18-15(17)11-6-4-5-10-9-16-12-7-2-3-8-13(12)19-14(10)11/h2-9H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	0.0603	n/a	n/a	n/a	n/a
Ferrara University Curated by ChEMBL					Assay Description Activation of human TRPA1 channel				J Med Chem 53: 5085-107 (2010) Article DOI: 10.1021/jm100062h BindingDB Entry DOI: 10.7270/Q2416Z02
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327675 (CHEMBL1084640 | Dibenzo[b,f][1,4]oxazepine-4-carbo...) Show SMILES NC(=O)c1cccc2C=Nc3ccccc3Oc12 |c:8| Show InChI InChI=1S/C14H10N2O2/c15-14(17)10-5-3-4-9-8-16-11-6-1-2-7-12(11)18-13(9)10/h1-8H,(H2,15,17)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0759	n/a	n/a	n/a	n/a
Ferrara University Curated by ChEMBL					Assay Description Activation of human TRPA1 channel				J Med Chem 53: 5085-107 (2010) Article DOI: 10.1021/jm100062h BindingDB Entry DOI: 10.7270/Q2416Z02
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327675 (CHEMBL1084640 | Dibenzo[b,f][1,4]oxazepine-4-carbo...) Show SMILES NC(=O)c1cccc2C=Nc3ccccc3Oc12 |c:8| Show InChI InChI=1S/C14H10N2O2/c15-14(17)10-5-3-4-9-8-16-11-6-1-2-7-12(11)18-13(9)10/h1-8H,(H2,15,17)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0800	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327658 (11H-Dibenzo[b,e]-azepine-10-carboxylic Acid Methyl...) Show SMILES COC(=O)c1cccc2C=Nc3ccccc3Cc12 |c:9| Show InChI InChI=1S/C16H13NO2/c1-19-16(18)13-7-4-6-12-10-17-15-8-3-2-5-11(15)9-14(12)13/h2-8,10H,9H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
Ferrara University Curated by ChEMBL					Assay Description Activation of human TRPA1 channel				J Med Chem 53: 5085-107 (2010) Article DOI: 10.1021/jm100062h BindingDB Entry DOI: 10.7270/Q2416Z02
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327673 (CHEMBL1256241 | Dibenzo[b,f][1,4]oxazepine-6-carbo...) Show SMILES N#Cc1cccc2N=Cc3ccccc3Oc12 |c:7| Show InChI InChI=1S/C14H8N2O/c15-8-10-5-3-6-12-14(10)17-13-7-2-1-4-11(13)9-16-12/h1-7,9H	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327676 (CHEMBL1084097 | Dibenzo[b,f][1,4]oxazepine-6-carbo...) Show SMILES NC(=O)c1cccc2N=Cc3ccccc3Oc12 |c:8| Show InChI InChI=1S/C14H10N2O2/c15-14(17)10-5-3-6-11-13(10)18-12-7-2-1-4-9(12)8-16-11/h1-8H,(H2,15,17)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.110	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327676 (CHEMBL1084097 | Dibenzo[b,f][1,4]oxazepine-6-carbo...) Show SMILES NC(=O)c1cccc2N=Cc3ccccc3Oc12 |c:8| Show InChI InChI=1S/C14H10N2O2/c15-14(17)10-5-3-6-11-13(10)18-12-7-2-1-4-9(12)8-16-11/h1-8H,(H2,15,17)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.115	n/a	n/a	n/a	n/a
Ferrara University Curated by ChEMBL					Assay Description Activation of human TRPA1 channel				J Med Chem 53: 5085-107 (2010) Article DOI: 10.1021/jm100062h BindingDB Entry DOI: 10.7270/Q2416Z02
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50415923 (CHEMBL1084098) Show SMILES COC(=O)c1cccc2N=Cc3ccccc3Oc12 |c:9| Show InChI InChI=1S/C15H11NO3/c1-18-15(17)11-6-4-7-12-14(11)19-13-8-3-2-5-10(13)9-16-12/h2-9H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.117	n/a	n/a	n/a	n/a
Ferrara University Curated by ChEMBL					Assay Description Activation of human TRPA1 channel				J Med Chem 53: 5085-107 (2010) Article DOI: 10.1021/jm100062h BindingDB Entry DOI: 10.7270/Q2416Z02
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327672 (CHEMBL1256240 | Dibenzo[b,f][1,4]oxazepine-4-carbo...) Show SMILES N#Cc1cccc2C=Nc3ccccc3Oc12 |c:7| Show InChI InChI=1S/C14H8N2O/c15-8-10-4-3-5-11-9-16-12-6-1-2-7-13(12)17-14(10)11/h1-7,9H	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.150	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50318511 (CHEMBL1085100 | dibenzo[b,f][1,4]oxazepine) Show SMILES O1c2ccccc2C=Nc2ccccc12 |c:8| Show InChI InChI=1S/C13H9NO/c1-3-7-12-10(5-1)9-14-11-6-2-4-8-13(11)15-12/h1-9H	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50318511 (CHEMBL1085100 | dibenzo[b,f][1,4]oxazepine) Show SMILES O1c2ccccc2C=Nc2ccccc12 |c:8| Show InChI InChI=1S/C13H9NO/c1-3-7-12-10(5-1)9-14-11-6-2-4-8-13(11)15-12/h1-9H	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.302	n/a	n/a	n/a	n/a
Ferrara University Curated by ChEMBL					Assay Description Activation of human TRPA1 channel				J Med Chem 53: 5085-107 (2010) Article DOI: 10.1021/jm100062h BindingDB Entry DOI: 10.7270/Q2416Z02
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327661 (11H-dibenzo[b,e]azepine-2-carboxylic acid methyl e...) Show SMILES COC(=O)c1ccc2N=Cc3ccccc3Cc2c1 |c:8| Show InChI InChI=1S/C16H13NO2/c1-19-16(18)12-6-7-15-14(9-12)8-11-4-2-3-5-13(11)10-17-15/h2-7,9-10H,8H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327661 (11H-dibenzo[b,e]azepine-2-carboxylic acid methyl e...) Show SMILES COC(=O)c1ccc2N=Cc3ccccc3Cc2c1 |c:8| Show InChI InChI=1S/C16H13NO2/c1-19-16(18)12-6-7-15-14(9-12)8-11-4-2-3-5-13(11)10-17-15/h2-7,9-10H,8H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.575	n/a	n/a	n/a	n/a
Ferrara University Curated by ChEMBL					Assay Description Activation of human TRPA1 channel				J Med Chem 53: 5085-107 (2010) Article DOI: 10.1021/jm100062h BindingDB Entry DOI: 10.7270/Q2416Z02
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327660 (11H-Dibenzo[b,e]azepine-1-carboxylic acid methyl e...) Show SMILES COC(=O)c1cccc2N=Cc3ccccc3Cc12 |c:9| Show InChI InChI=1S/C16H13NO2/c1-19-16(18)13-7-4-8-15-14(13)9-11-5-2-3-6-12(11)10-17-15/h2-8,10H,9H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.575	n/a	n/a	n/a	n/a
Ferrara University Curated by ChEMBL					Assay Description Activation of human TRPA1 channel				J Med Chem 53: 5085-107 (2010) Article DOI: 10.1021/jm100062h BindingDB Entry DOI: 10.7270/Q2416Z02
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327660 (11H-Dibenzo[b,e]azepine-1-carboxylic acid methyl e...) Show SMILES COC(=O)c1cccc2N=Cc3ccccc3Cc12 |c:9| Show InChI InChI=1S/C16H13NO2/c1-19-16(18)13-7-4-8-15-14(13)9-11-5-2-3-6-12(11)10-17-15/h2-8,10H,9H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327657 (2-chlorobenzylidenemalononitrile | CHEMBL1256101) Show SMILES Clc1ccccc1\[#6]=[#6](\C#N)C#N Show InChI InChI=1S/C10H5ClN2/c11-10-4-2-1-3-9(10)5-8(6-12)7-13/h1-5H	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	0.900	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327671 (11H-Dibenzo[b,e]azepine-10-carbonitrile hydrochlor...) Show SMILES N#Cc1cccc2C=Nc3ccccc3Cc12 |c:7| Show InChI InChI=1S/C15H10N2/c16-9-12-5-3-6-13-10-17-15-7-2-1-4-11(15)8-14(12)13/h1-7,10H,8H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327656 (CHEMBL1256339 | Dibenzo[b,f][1,4]oxazepin-3-o) Show SMILES Oc1ccc2C=Nc3ccccc3Oc2c1 |c:5| Show InChI InChI=1S/C13H9NO2/c15-10-6-5-9-8-14-11-3-1-2-4-12(11)16-13(9)7-10/h1-8,15H	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.10	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327674 (11H-Dibenzo[b,e]azepine-10-carboxylic amide | CHEM...) Show SMILES NC(=O)c1cccc2C=Nc3ccccc3Cc12 |c:8| Show InChI InChI=1S/C15H12N2O/c16-15(18)12-6-3-5-11-9-17-14-7-2-1-4-10(14)8-13(11)12/h1-7,9H,8H2,(H2,16,18)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327659 (11H-dibenzo[b,e]azepine | CHEMBL1085101 | morphant...) Show SMILES C1c2ccccc2C=Nc2ccccc12 |c:8| Show InChI InChI=1S/C14H11N/c1-2-7-13-10-15-14-8-4-3-6-12(14)9-11(13)5-1/h1-8,10H,9H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327659 (11H-dibenzo[b,e]azepine | CHEMBL1085101 | morphant...) Show SMILES C1c2ccccc2C=Nc2ccccc12 |c:8| Show InChI InChI=1S/C14H11N/c1-2-7-13-10-15-14-8-4-3-6-12(14)9-11(13)5-1/h1-8,10H,9H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.02	n/a	n/a	n/a	n/a
Ferrara University Curated by ChEMBL					Assay Description Activation of human TRPA1 channel				J Med Chem 53: 5085-107 (2010) Article DOI: 10.1021/jm100062h BindingDB Entry DOI: 10.7270/Q2416Z02
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327669 (10-Bromo-11H-dibenzo[b,e]azepine hydrochloride | C...) Show SMILES Brc1cccc2C=Nc3ccccc3Cc12 |c:6| Show InChI InChI=1S/C14H10BrN/c15-13-6-3-5-11-9-16-14-7-2-1-4-10(14)8-12(11)13/h1-7,9H,8H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.5	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327658 (11H-Dibenzo[b,e]-azepine-10-carboxylic Acid Methyl...) Show SMILES COC(=O)c1cccc2C=Nc3ccccc3Cc12 |c:9| Show InChI InChI=1S/C16H13NO2/c1-19-16(18)13-7-4-6-12-10-17-15-8-3-2-5-11(15)9-14(12)13/h2-8,10H,9H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.40	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as time point of maximal current amplitude by patch-clamp electrophysiology				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327666 (CHEMBL1085943 | Dibenzo[b,f][1,4]oxazepine-3-carbo...) Show SMILES COC(=O)c1ccc2C=Nc3ccccc3Oc2c1 |c:8| Show InChI InChI=1S/C15H11NO3/c1-18-15(17)10-6-7-11-9-16-12-4-2-3-5-13(12)19-14(11)8-10/h2-9H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327678 (11H-dibenzo[b,e]azepine-10-carboxylic acid butyl e...) Show SMILES CCCCOC(=O)c1cccc2C=Nc3ccccc3Cc12 |c:12| Show InChI InChI=1S/C19H19NO2/c1-2-3-11-22-19(21)16-9-6-8-15-13-20-18-10-5-4-7-14(18)12-17(15)16/h4-10,13H,2-3,11-12H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.20	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327667 (CHEMBL1084637 | Dibenzo[b,f][1,4]oxazepine-4-carbo...) Show SMILES COC(=O)c1cccc2C=Nc3ccccc3Oc12 |c:9| Show InChI InChI=1S/C15H11NO3/c1-18-15(17)11-6-4-5-10-9-16-12-7-2-3-8-13(12)19-14(10)11/h2-9H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	7.40	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as time point of maximal current amplitude by patch-clamp electrophysiology				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327680 (11H-Dibenzo[b,e]azepine-10-carboxylic acid(3-metho...) Show SMILES COCCCNC(=O)c1cccc2C=Nc3ccccc3Cc12 |c:13| Show InChI InChI=1S/C19H20N2O2/c1-23-11-5-10-20-19(22)16-8-4-7-15-13-21-18-9-3-2-6-14(18)12-17(15)16/h2-4,6-9,13H,5,10-12H2,1H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.70	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327678 (11H-dibenzo[b,e]azepine-10-carboxylic acid butyl e...) Show SMILES CCCCOC(=O)c1cccc2C=Nc3ccccc3Cc12 |c:12| Show InChI InChI=1S/C19H19NO2/c1-2-3-11-22-19(21)16-9-6-8-15-13-20-18-10-5-4-7-14(18)12-17(15)16/h4-10,13H,2-3,11-12H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.51	n/a	n/a	n/a	n/a
Ferrara University Curated by ChEMBL					Assay Description Activation of human TRPA1 channel				J Med Chem 53: 5085-107 (2010) Article DOI: 10.1021/jm100062h BindingDB Entry DOI: 10.7270/Q2416Z02
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327654 (CHEMBL1256377 | dibenzo[b,f][1,4]thiazepine) Show SMILES S1c2ccccc2C=Nc2ccccc12 |c:8| Show InChI InChI=1S/C13H9NS/c1-3-7-12-10(5-1)9-14-11-6-2-4-8-13(11)15-12/h1-9H	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327658 (11H-Dibenzo[b,e]-azepine-10-carboxylic Acid Methyl...) Show SMILES COC(=O)c1cccc2C=Nc3ccccc3Cc12 |c:9| Show InChI InChI=1S/C16H13NO2/c1-19-16(18)13-7-4-6-12-10-17-15-8-3-2-5-11(15)9-14(12)13/h2-8,10H,9H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	9.80	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells at 75 mV holding potential by patch-clamp electrophysiology				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50318515 (CHEMBL1085832 | bromo benzyl cyanide) Show SMILES BrC(C#N)c1ccccc1 Show InChI InChI=1S/C8H6BrN/c9-8(6-10)7-4-2-1-3-5-7/h1-5,8H	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50362768 (CHEMBL1939828) Show SMILES COc1cccc(c1)[C@H]1NC(=S)N=C2C1C(=O)c1ccccc21 |r,c:13| Show InChI InChI=1S/C18H14N2O2S/c1-22-11-6-4-5-10(9-11)15-14-16(20-18(23)19-15)12-7-2-3-8-13(12)17(14)21/h2-9,14-15H,1H3,(H,19,23)/t14?,15-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Janssen Research& Development, Janssen Pharmaceutica N.V. Curated by ChEMBL					Assay Description Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as inhibition of N-methyl-maleimide-induced current by patch clamp assay				Bioorg Med Chem Lett 22: 797-800 (2012) Article DOI: 10.1016/j.bmcl.2011.12.068 BindingDB Entry DOI: 10.7270/Q2736RC4
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50318515 (CHEMBL1085832 | bromo benzyl cyanide) Show SMILES BrC(C#N)c1ccccc1 Show InChI InChI=1S/C8H6BrN/c9-8(6-10)7-4-2-1-3-5-7/h1-5,8H	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Ferrara University Curated by ChEMBL					Assay Description Activation of human TRPA1 channel				J Med Chem 53: 5085-107 (2010) Article DOI: 10.1021/jm100062h BindingDB Entry DOI: 10.7270/Q2416Z02
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327655 (3-methoxydibenzo[b,f][1,4]oxazepine | CHEMBL125631...) Show SMILES COc1ccc2C=Nc3ccccc3Oc2c1 |c:6| Show InChI InChI=1S/C14H11NO2/c1-16-11-7-6-10-9-15-12-4-2-3-5-13(12)17-14(10)8-11/h2-9H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327662 (11H-Dibenzo[b,e]azepine-3-carboxylic acid methyl e...) Show SMILES COC(=O)c1ccc2Cc3ccccc3C=Nc2c1 |c:16| Show InChI InChI=1S/C16H13NO2/c1-19-16(18)13-7-6-12-8-11-4-2-3-5-14(11)10-17-15(12)9-13/h2-7,9-10H,8H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50350947 (CHEMBL1818218) Show SMILES CC(C)CNc1nc(ncc1C(=O)NCc1ccccc1)N1CCN(CC2CCCOC2)CC1 Show InChI InChI=1S/C26H38N6O2/c1-20(2)15-27-24-23(25(33)28-16-21-7-4-3-5-8-21)17-29-26(30-24)32-12-10-31(11-13-32)18-22-9-6-14-34-19-22/h3-5,7-8,17,20,22H,6,9-16,18-19H2,1-2H3,(H,28,33)(H,27,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 channel expressed in HEK293 cells assessed as calcium influx measured at every 1 second for 60 seconds by fluorescenc...				Bioorg Med Chem Lett 21: 4857-9 (2011) Article DOI: 10.1016/j.bmcl.2011.06.035 BindingDB Entry DOI: 10.7270/Q21Z44S2
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327667 (CHEMBL1084637 | Dibenzo[b,f][1,4]oxazepine-4-carbo...) Show SMILES COC(=O)c1cccc2C=Nc3ccccc3Oc12 |c:9| Show InChI InChI=1S/C15H11NO3/c1-18-15(17)11-6-4-5-10-9-16-12-7-2-3-8-13(12)19-14(10)11/h2-9H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells at 75 mV holding potential by patch-clamp electrophysiology				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50350949 (CHEMBL1818214) Show SMILES Fc1cccc(F)c1C(=O)N1CCN(CC1)c1ncc(C(=O)NCc2ccccc2)c(NC2CC2)n1 Show InChI InChI=1S/C26H26F2N6O2/c27-20-7-4-8-21(28)22(20)25(36)33-11-13-34(14-12-33)26-30-16-19(23(32-26)31-18-9-10-18)24(35)29-15-17-5-2-1-3-6-17/h1-8,16,18H,9-15H2,(H,29,35)(H,30,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 channel expressed in HEK293 cells assessed as calcium influx measured at every 1 second for 60 seconds by fluorescenc...				Bioorg Med Chem Lett 21: 4857-9 (2011) Article DOI: 10.1016/j.bmcl.2011.06.035 BindingDB Entry DOI: 10.7270/Q21Z44S2
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM7873 (2-chloro-1-phenylethan-1-one | CHEMBL105712 | Halo...) Show SMILES ClCC(=O)c1ccccc1 Show InChI InChI=1S/C8H7ClO/c9-6-8(10)7-4-2-1-3-5-7/h1-5H,6H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327663 (11H-dibenzo[b,e]azepine-4-carboxylic acid methyl e...) Show SMILES COC(=O)c1cccc2Cc3ccccc3C=Nc12 |c:17| Show InChI InChI=1S/C16H13NO2/c1-19-16(18)14-8-4-7-12-9-11-5-2-3-6-13(11)10-17-15(12)14/h2-8,10H,9H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327664 (11H-Dibenzo[b,e]azepine-7-carboxylic acid methyl e...) Show SMILES COC(=O)c1cccc2Cc3ccccc3N=Cc12 |c:17| Show InChI InChI=1S/C16H13NO2/c1-19-16(18)13-7-4-6-11-9-12-5-2-3-8-15(12)17-10-14(11)13/h2-8,10H,9H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327668 (8-Bromo-11H-dibenzo[b,e]azepine | CHEMBL1255819) Show SMILES Brc1ccc2Cc3ccccc3N=Cc2c1 |c:13| Show InChI InChI=1S/C14H10BrN/c15-13-6-5-10-7-11-3-1-2-4-14(11)16-9-12(10)8-13/h1-6,8-9H,7H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	33	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327658 (11H-Dibenzo[b,e]-azepine-10-carboxylic Acid Methyl...) Show SMILES COC(=O)c1cccc2C=Nc3ccccc3Cc12 |c:9| Show InChI InChI=1S/C16H13NO2/c1-19-16(18)13-7-4-6-12-10-17-15-8-3-2-5-11(15)9-14(12)13/h2-8,10H,9H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	38	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells at -30 mV holding potential by patch-clamp electrophysiology				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327658 (11H-Dibenzo[b,e]-azepine-10-carboxylic Acid Methyl...) Show SMILES COC(=O)c1cccc2C=Nc3ccccc3Cc12 |c:9| Show InChI InChI=1S/C16H13NO2/c1-19-16(18)13-7-4-6-12-10-17-15-8-3-2-5-11(15)9-14(12)13/h2-8,10H,9H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	38	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells at -30 mV holding potential by patch-clamp electrophysiology				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50318514 (CHEMBL1085948 | ethyl bromo acetate) Show SMILES CCOC(=O)CBr Show InChI InChI=1S/C4H7BrO2/c1-2-7-4(6)3-5/h2-3H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
Ferrara University Curated by ChEMBL					Assay Description Activation of human TRPA1 channel				J Med Chem 53: 5085-107 (2010) Article DOI: 10.1021/jm100062h BindingDB Entry DOI: 10.7270/Q2416Z02
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327681 (11H-Dibenzo[b,e]azepine-10-carboxylic acid diethyl...) Show SMILES CCN(CC)C(=O)c1cccc2C=Nc3ccccc3Cc12 |c:12| Show InChI InChI=1S/C19H20N2O/c1-3-21(4-2)19(22)16-10-7-9-15-13-20-18-11-6-5-8-14(18)12-17(15)16/h5-11,13H,3-4,12H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50350950 (CHEMBL1818210) Show SMILES CC(C)CNc1nc(ncc1C(=O)NCc1cccnc1)N1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C26H33N7O/c1-20(2)15-28-24-23(25(34)29-17-22-9-6-10-27-16-22)18-30-26(31-24)33-13-11-32(12-14-33)19-21-7-4-3-5-8-21/h3-10,16,18,20H,11-15,17,19H2,1-2H3,(H,29,34)(H,28,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	49	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 channel expressed in HEK293 cells assessed as calcium influx measured at every 1 second for 60 seconds by fluorescenc...				Bioorg Med Chem Lett 21: 4857-9 (2011) Article DOI: 10.1016/j.bmcl.2011.06.035 BindingDB Entry DOI: 10.7270/Q21Z44S2
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327666 (CHEMBL1085943 | Dibenzo[b,f][1,4]oxazepine-3-carbo...) Show SMILES COC(=O)c1ccc2C=Nc3ccccc3Oc2c1 |c:8| Show InChI InChI=1S/C15H11NO3/c1-18-15(17)10-6-7-11-9-16-12-4-2-3-5-13(12)19-14(11)8-10/h2-9H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	52.5	n/a	n/a	n/a	n/a
Ferrara University Curated by ChEMBL					Assay Description Activation of human TRPA1 channel				J Med Chem 53: 5085-107 (2010) Article DOI: 10.1021/jm100062h BindingDB Entry DOI: 10.7270/Q2416Z02
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50318479 ((1R,4aS,8aS)-5,5,8a-trimethyl-1,4,4a,5,6,7,8,8a-oc...) Show SMILES CC1(C)CCC[C@@]2(C)[C@H]1CC=C(C=O)[C@@H]2C=O |r,t:11| Show InChI InChI=1S/C15H22O2/c1-14(2)7-4-8-15(3)12(10-17)11(9-16)5-6-13(14)15/h5,9-10,12-13H,4,6-8H2,1-3H3/t12-,13-,15+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	59	n/a	n/a	n/a	n/a
Ferrara University Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 channel expressed in CHO cells assessed as increase in intracellular calcium levels				J Med Chem 53: 5085-107 (2010) Article DOI: 10.1021/jm100062h BindingDB Entry DOI: 10.7270/Q2416Z02
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50511105 (GWP-42004 | Gwp42004 | O-4394 | THCV | Tetrahydroc...) Show SMILES [H][C@@]12C=C(C)CC[C@@]1([H])C(C)(C)Oc1cc(CCC)cc(O)c21 |r,t:2| Show InChI InChI=1S/C19H26O2/c1-5-6-13-10-16(20)18-14-9-12(2)7-8-15(14)19(3,4)21-17(18)11-13/h9-11,14-15,20H,5-8H2,1-4H3/t14-,15-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jnatprod.0c00965 BindingDB Entry DOI: 10.7270/Q2057KWP
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 338 total )  |  Next  |  Last  >>

Jump to: