Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50156310 (4-(3-(3-benzenesulfonylfuroxan-4-yloxy)propyl)phen...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips | J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50156304 (3-benzenesulfonyl-4-ethoxy-furazan 2-oxide | 4-eth...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips | J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50029051 ((-)-arterenol | (-)-noradrenaline | (-)-norepineph...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro agonist potency towards Alpha-1D adrenergic receptor in rat aorta | J Med Chem 39: 4116-9 (1996) Article DOI: 10.1021/jm960354u BindingDB Entry DOI: 10.7270/Q2FN18WJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50186605 (4-(3-(3-benzenesulfonylfuroxan-4-yloxy)propyl)-2,6...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 22 | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips | J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50156303 (2-(3-benzenesulfonylfuroxan-4-yloxymethyl)-2,5,7,8...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 44 | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips | J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50156308 (4-(3-(3-benzenesulfonylfuroxan-4-yloxy)propyl)-2,6...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips | J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50186606 (3-(4-hydroxyphenyl)prop-1,2-diyl dinitrate | CHEMB...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 130 | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips | J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50067212 (CHEBI:8093 | Cyclomydril | Duo-Medihaler | Phenyle...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 155 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro agonist potency towards Alpha-1D adrenergic receptor in rat aorta | J Med Chem 39: 4116-9 (1996) Article DOI: 10.1021/jm960354u BindingDB Entry DOI: 10.7270/Q2FN18WJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50186612 (1,2-bis-nitrooxy-propane | CHEMBL206527) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 240 | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips | J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50156310 (4-(3-(3-benzenesulfonylfuroxan-4-yloxy)propyl)phen...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 360 | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips in presence of 1 uM ODQ | J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50186604 (4-((N-(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propyl...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 410 | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips | J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50131411 (4-(4-Chloro-benzyl)-2-methyl-2H-phthalazin-1-one |...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 430 | n/a | n/a | n/a | n/a |
Universidad de Salamanca Curated by ChEMBL | Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction | Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50186605 (4-(3-(3-benzenesulfonylfuroxan-4-yloxy)propyl)-2,6...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 500 | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips in presence of 1 uM ODQ | J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50186608 (3-((4-hydroxy-3,5-dimethoxy)phenyl)prop-1,2-diyl d...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 640 | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips | J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50156303 (2-(3-benzenesulfonylfuroxan-4-yloxymethyl)-2,5,7,8...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 670 | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips in presence of 1 uM ODQ | J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM56339 (4-(4-chlorobenzyl)-1(2H)-phthalazinone | 4-(4-chlo...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 790 | n/a | n/a | n/a | n/a |
Universidad de Salamanca Curated by ChEMBL | Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction | Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50131402 (4-(benzo[d][1,3]dioxol-5-ylmethyl)-2-methylphthala...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 930 | n/a | n/a | n/a | n/a |
Universidad de Salamanca Curated by ChEMBL | Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction | Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50183669 (4-(4-(methylthio)benzyl)-2-methylphthalazin-1(2H)-...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 930 | n/a | n/a | n/a | n/a |
Universidad de Salamanca Curated by ChEMBL | Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction | Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50156307 (3-(4-hydroxyphenyl)propyl nitrate | 4-(3-Nitrooxy-...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips | J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50470944 (CHEMBL336161) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.02E+3 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro agonist potency towards Alpha-1D adrenergic receptor in rat aorta | J Med Chem 39: 4116-9 (1996) Article DOI: 10.1021/jm960354u BindingDB Entry DOI: 10.7270/Q2FN18WJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50156305 (2,5,7,8-Tetramethyl-2-(3-nitrooxy-propoxymethyl)-c...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips | J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50183666 (4-(2,4-dichlorobenzyl)-2-methylphthalazin-1(2H)-on...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a |
Universidad de Salamanca Curated by ChEMBL | Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction | Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50183687 (4-(4-chlorobenzyl)-2-ethylphthalazin-1(2H)-one | C...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a |
Universidad de Salamanca Curated by ChEMBL | Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction | Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50183690 (4-(2-chlorobenzyl)-2-methylphthalazin-1(2H)-one | ...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a |
Universidad de Salamanca Curated by ChEMBL | Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction | Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50186603 (4-((N-((6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips | J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50118702 (2-Amino-1-(2,5-dimethoxy-phenyl)-ethanol | CHEMBL1...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | n/a | n/a | 1.86E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at alpha1D adrenoreceptor in Rattus norvegicus (rat) aorta | Citation and Details Article DOI: 10.1007/s00044-004-0020-z BindingDB Entry DOI: 10.7270/Q2PZ5CQB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50118702 (2-Amino-1-(2,5-dimethoxy-phenyl)-ethanol | CHEMBL1...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Effective concentration of the compound was determined in vitro against rat aorta Alpha-1D adrenergic receptor;* indicates EC50 < 15% at a concentrat... | J Med Chem 45: 4395-7 (2002) BindingDB Entry DOI: 10.7270/Q20001FV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50183678 (4-(2-chlorobenzyl)phthalazin-1(2H)-one | CHEMBL378...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a |
Universidad de Salamanca Curated by ChEMBL | Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction | Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50131408 (4-(3,4-Dimethoxy-benzyl)-2-methyl-2H-phthalazin-1-...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a |
Universidad de Salamanca Curated by ChEMBL | Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction | Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50118703 (CHEMBL109783 | N-[5-(4,5-Dihydro-1H-imidazol-2-yl)...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents | Article | n/a | n/a | n/a | n/a | 2.57E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at alpha1D adrenoreceptor in Rattus norvegicus (rat) aorta | Citation and Details Article DOI: 10.1007/s00044-004-0020-z BindingDB Entry DOI: 10.7270/Q2PZ5CQB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50118703 (CHEMBL109783 | N-[5-(4,5-Dihydro-1H-imidazol-2-yl)...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | 2.57E+3 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro agonist potency towards Alpha-1D adrenergic receptor in rat aorta | J Med Chem 39: 4116-9 (1996) Article DOI: 10.1021/jm960354u BindingDB Entry DOI: 10.7270/Q2FN18WJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50118703 (CHEMBL109783 | N-[5-(4,5-Dihydro-1H-imidazol-2-yl)...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents | PubMed | n/a | n/a | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Effective concentration of the compound was determined in vitro against rat aorta Alpha-1D adrenergic receptor;* indicates EC50 < 15% at a concentrat... | J Med Chem 45: 4395-7 (2002) BindingDB Entry DOI: 10.7270/Q20001FV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50183665 (4-(4-chlorobenzyl)-2-allylphthalazin-1(2H)-one | C...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a |
Universidad de Salamanca Curated by ChEMBL | Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction | Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50131414 (4-(benzo[d][1,3]dioxol-5-ylmethyl)phthalazin-1(2H)...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a |
Universidad de Salamanca Curated by ChEMBL | Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction | Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50186607 (4-dimethylaminomethyl-2-oxy-furazan-3-carboxylic a...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips | J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50186610 (3-((4-hydroxy-3,5-di-tert-butyl)phenyl)prop-1,2-di...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips | J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50131410 (4-(3,4-Dimethoxy-benzyl)-2H-phthalazin-1-one | 4-(...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a |
Universidad de Salamanca Curated by ChEMBL | Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction | Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50186611 (3-(4-hydroxy-3,5-dimethoxyphenyl)propyl nitrate | ...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips | J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50183683 (4-(naphthalen-1-ylmethyl)phthalazin-1(2H)-one | CH...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a |
Universidad de Salamanca Curated by ChEMBL | Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction | Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50156308 (4-(3-(3-benzenesulfonylfuroxan-4-yloxy)propyl)-2,6...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips in presence of 1 uM ODQ | J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50183680 (4-(3,4-dichlorobenzyl)-2-methylphthalazin-1(2H)-on...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a |
Universidad de Salamanca Curated by ChEMBL | Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction | Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50183667 (4-(3,4-dimethoxybenzyl)-2-ethylphthalazin-1(2H)-on...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a |
Universidad de Salamanca Curated by ChEMBL | Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction | Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50183677 (4-(3,4-dimethoxybenzyl)-2-butylphthalazin-1(2H)-on...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a |
Universidad de Salamanca Curated by ChEMBL | Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction | Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50183675 (4-(4-(methylthio)benzyl)phthalazin-1(2H)-one | CHE...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a |
Universidad de Salamanca Curated by ChEMBL | Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction | Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50186613 (4-hydroxymethyl-2-oxy-furazan-3-carboxylic acid am...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips | J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50186604 (4-((N-(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propyl...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 7.40E+3 | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips in presence of 1 uM ODQ | J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM30712 (6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 8.32E+3 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro agonist potency towards Alpha-1D adrenergic receptor in rat aorta | J Med Chem 39: 4116-9 (1996) Article DOI: 10.1021/jm960354u BindingDB Entry DOI: 10.7270/Q2FN18WJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50183679 (4-(3,4-dimethoxybenzyl)-2-allylphthalazin-1(2H)-on...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 9.80E+3 | n/a | n/a | n/a | n/a |
Universidad de Salamanca Curated by ChEMBL | Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction | Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50131404 (4-(4-Methoxy-benzyl)-2H-phthalazin-1-one | 4-(4-me...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Universidad de Salamanca Curated by ChEMBL | Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction | Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50183685 (4-(naphthalen-2-ylmethyl)phthalazin-1(2H)-one | CH...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Universidad de Salamanca Curated by ChEMBL | Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction | Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N | |||||||||||
More data for this Ligand-Target Pair |
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