Compile Data Set for Download or QSAR

Found 315 hits of ic50 data for polymerid = 1023,179   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191235 (US9181272, 5) Show SMILES Cc1ccncc1-c1cnc2N(CCCc2c1)C(N)=O Show InChI InChI=1S/C15H16N4O/c1-10-4-5-17-9-13(10)12-7-11-3-2-6-19(15(16)20)14(11)18-8-12/h4-5,7-9H,2-3,6H2,1H3,(H2,16,20)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191250 (US9181272, 20) Show SMILES Cc1cncc(c1)-c1cnc2N(CCCc2c1)C(N)=O Show InChI InChI=1S/C15H16N4O/c1-10-5-12(8-17-7-10)13-6-11-3-2-4-19(15(16)20)14(11)18-9-13/h5-9H,2-4H2,1H3,(H2,16,20)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191414 (US9181272, 184 | US9181272, 195 | US9181272, 196) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(c1)C(O)C(F)(F)F Show InChI InChI=1S/C16H15F3N4O2/c17-16(18,19)13(24)12-5-10(6-21-7-12)11-4-9-2-1-3-23(15(20)25)14(9)22-8-11/h4-8,13,24H,1-3H2,(H2,20,25)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191361 (US9181272, 131) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(c1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C20H19N5O3S/c21-20(26)25-7-1-2-14-8-17(12-24-19(14)25)16-9-15(10-23-11-16)13-3-5-18(6-4-13)29(22,27)28/h3-6,8-12H,1-2,7H2,(H2,21,26)(H2,22,27,28)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191385 (US9181272, 155) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(Cl)c1C#N Show InChI InChI=1S/C15H12ClN5O/c16-13-8-19-7-12(11(13)5-17)10-4-9-2-1-3-21(15(18)22)14(9)20-6-10/h4,6-8H,1-3H2,(H2,18,22)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191255 (US9181272, 25) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cnccc1F Show InChI InChI=1S/C14H13FN4O/c15-12-3-4-17-8-11(12)10-6-9-2-1-5-19(14(16)20)13(9)18-7-10/h3-4,6-8H,1-2,5H2,(H2,16,20)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191522 (US9181272, 292) Show SMILES NC(=O)N1CCc2cc(cnc12)-c1cnccc1C(F)(F)F Show InChI InChI=1S/C14H11F3N4O/c15-14(16,17)11-1-3-19-7-10(11)9-5-8-2-4-21(13(18)22)12(8)20-6-9/h1,3,5-7H,2,4H2,(H2,18,22)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.20	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191519 (US9181272, 289) Show SMILES Cc1ccncc1-c1cnc2N(CCc2c1)C(N)=O Show InChI InChI=1S/C14H14N4O/c1-9-2-4-16-8-12(9)11-6-10-3-5-18(14(15)19)13(10)17-7-11/h2,4,6-8H,3,5H2,1H3,(H2,15,19)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.20	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191372 (US9181272, 142) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(c1)-c1ccc(CC#N)cc1 Show InChI InChI=1S/C22H19N5O/c23-8-7-15-3-5-16(6-4-15)18-11-19(13-25-12-18)20-10-17-2-1-9-27(22(24)28)21(17)26-14-20/h3-6,10-14H,1-2,7,9H2,(H2,24,28)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.30	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191346 (US9181272, 116) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(NCc2ccccc2)c1 Show InChI InChI=1S/C21H21N5O/c22-21(27)26-8-4-7-16-9-17(13-25-20(16)26)18-10-19(14-23-12-18)24-11-15-5-2-1-3-6-15/h1-3,5-6,9-10,12-14,24H,4,7-8,11H2,(H2,22,27)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191366 (US9181272, 136) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(c1)-c1cccc(CC#N)c1 Show InChI InChI=1S/C22H19N5O/c23-7-6-15-3-1-4-16(9-15)18-11-19(13-25-12-18)20-10-17-5-2-8-27(22(24)28)21(17)26-14-20/h1,3-4,9-14H,2,5-6,8H2,(H2,24,28)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191239 (US9181272, 9) Show SMILES COc1cncc(c1)-c1cnc2N(CCCc2c1)C(N)=O Show InChI InChI=1S/C15H16N4O2/c1-21-13-6-12(7-17-9-13)11-5-10-3-2-4-19(15(16)20)14(10)18-8-11/h5-9H,2-4H2,1H3,(H2,16,20)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191494 (US9181272, 264) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(c1)C1(CC1)C#N Show InChI InChI=1S/C18H17N5O/c19-11-18(3-4-18)15-7-14(8-21-10-15)13-6-12-2-1-5-23(17(20)24)16(12)22-9-13/h6-10H,1-5H2,(H2,20,24)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.70	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191268 (US9181272, 38) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cncc(c1)-c1cnc2N(CCCc2c1)C(N)=O Show InChI InChI=1S/C21H20N4O3S/c1-29(27,28)19-6-4-14(5-7-19)16-10-17(12-23-11-16)18-9-15-3-2-8-25(21(22)26)20(15)24-13-18/h4-7,9-13H,2-3,8H2,1H3,(H2,22,26)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191467 (US9181272, 237) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(c1)C1CC1 Show InChI InChI=1S/C17H18N4O/c18-17(22)21-5-1-2-12-6-15(10-20-16(12)21)14-7-13(8-19-9-14)11-3-4-11/h6-11H,1-5H2,(H2,18,22)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.10	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191414 (US9181272, 184 | US9181272, 195 | US9181272, 196) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(c1)C(O)C(F)(F)F Show InChI InChI=1S/C16H15F3N4O2/c17-16(18,19)13(24)12-5-10(6-21-7-12)11-4-9-2-1-3-23(15(20)25)14(9)22-8-11/h4-8,13,24H,1-3H2,(H2,20,25)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191458 (US9181272, 228) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(COCC(=O)N2CCCCC2)c1 Show InChI InChI=1S/C22H27N5O3/c23-22(29)27-8-4-5-17-10-19(13-25-21(17)27)18-9-16(11-24-12-18)14-30-15-20(28)26-6-2-1-3-7-26/h9-13H,1-8,14-15H2,(H2,23,29)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191489 (US9181272, 259) Show SMILES CC(C#N)c1cncc(c1)-c1cnc2N(CCCc2c1)C(N)=O Show InChI InChI=1S/C17H17N5O/c1-11(7-18)13-6-14(9-20-8-13)15-5-12-3-2-4-22(17(19)23)16(12)21-10-15/h5-6,8-11H,2-4H2,1H3,(H2,19,23)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.40	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191311 (US9181272, 81) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(OCC2CCOCC2)c1 Show InChI InChI=1S/C20H24N4O3/c21-20(25)24-5-1-2-15-8-16(11-23-19(15)24)17-9-18(12-22-10-17)27-13-14-3-6-26-7-4-14/h8-12,14H,1-7,13H2,(H2,21,25)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191374 (US9181272, 144) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(c1)-c1ccccc1CO Show InChI InChI=1S/C21H20N4O2/c22-21(27)25-7-3-5-14-8-17(12-24-20(14)25)16-9-18(11-23-10-16)19-6-2-1-4-15(19)13-26/h1-2,4,6,8-12,26H,3,5,7,13H2,(H2,22,27)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191253 (US9181272, 23) Show SMILES COC(=O)c1cncc(c1)-c1cnc2N(CCCc2c1)C(N)=O Show InChI InChI=1S/C16H16N4O3/c1-23-15(21)13-6-11(7-18-8-13)12-5-10-3-2-4-20(16(17)22)14(10)19-9-12/h5-9H,2-4H2,1H3,(H2,17,22)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191259 (US9181272, 29) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cnccc1Cl Show InChI InChI=1S/C14H13ClN4O/c15-12-3-4-17-8-11(12)10-6-9-2-1-5-19(14(16)20)13(9)18-7-10/h3-4,6-8H,1-2,5H2,(H2,16,20)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.10	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191414 (US9181272, 184 | US9181272, 195 | US9181272, 196) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(c1)C(O)C(F)(F)F Show InChI InChI=1S/C16H15F3N4O2/c17-16(18,19)13(24)12-5-10(6-21-7-12)11-4-9-2-1-3-23(15(20)25)14(9)22-8-11/h4-8,13,24H,1-3H2,(H2,20,25)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.20	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191324 (US9181272, 94) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(c1)C1(O)CCC1 Show InChI InChI=1S/C18H20N4O2/c19-17(23)22-6-1-3-12-7-13(10-21-16(12)22)14-8-15(11-20-9-14)18(24)4-2-5-18/h7-11,24H,1-6H2,(H2,19,23)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.20	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191310 (US9181272, 80) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(O)c1 Show InChI InChI=1S/C14H14N4O2/c15-14(20)18-3-1-2-9-4-10(7-17-13(9)18)11-5-12(19)8-16-6-11/h4-8,19H,1-3H2,(H2,15,20)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.20	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191287 (US9181272, 57) Show SMILES CNC(=O)c1ccc(cc1)-c1cncc(c1)-c1cnc2N(CCCc2c1)C(N)=O Show InChI InChI=1S/C22H21N5O2/c1-24-21(28)15-6-4-14(5-7-15)17-10-18(12-25-11-17)19-9-16-3-2-8-27(22(23)29)20(16)26-13-19/h4-7,9-13H,2-3,8H2,1H3,(H2,23,29)(H,24,28)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.20	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191261 (US9181272, 31) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(c1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H17FN4O/c21-18-5-3-13(4-6-18)15-9-16(11-23-10-15)17-8-14-2-1-7-25(20(22)26)19(14)24-12-17/h3-6,8-12H,1-2,7H2,(H2,22,26)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.20	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191244 (US9181272, 14) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(c1)-c1ccccc1 Show InChI InChI=1S/C20H18N4O/c21-20(25)24-8-4-7-15-9-18(13-23-19(15)24)17-10-16(11-22-12-17)14-5-2-1-3-6-14/h1-3,5-6,9-13H,4,7-8H2,(H2,21,25)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.30	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191380 (US9181272, 150) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(c1)-c1ccc(nc1)N1CCOCC1 Show InChI InChI=1S/C23H24N6O2/c24-23(30)29-5-1-2-16-10-20(15-27-22(16)29)19-11-18(12-25-13-19)17-3-4-21(26-14-17)28-6-8-31-9-7-28/h3-4,10-15H,1-2,5-9H2,(H2,24,30)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.40	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191286 (US9181272, 56) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(COc2ccc(F)cc2)c1 Show InChI InChI=1S/C21H19FN4O2/c22-18-3-5-19(6-4-18)28-13-14-8-16(11-24-10-14)17-9-15-2-1-7-26(21(23)27)20(15)25-12-17/h3-6,8-12H,1-2,7,13H2,(H2,23,27)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.40	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191282 (US9181272, 52) Show SMILES Cn1c(cc2ccccc12)-c1cncc(-c2cnc3N(CCCc3c2)C(N)=O)c1C#N Show InChI InChI=1S/C24H20N6O/c1-29-21-7-3-2-5-15(21)10-22(29)20-14-27-13-19(18(20)11-25)17-9-16-6-4-8-30(24(26)31)23(16)28-12-17/h2-3,5,7,9-10,12-14H,4,6,8H2,1H3,(H2,26,31)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.70	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191297 (US9181272, 67) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cnccc1C(F)(F)F Show InChI InChI=1S/C15H13F3N4O/c16-15(17,18)12-3-4-20-8-11(12)10-6-9-2-1-5-22(14(19)23)13(9)21-7-10/h3-4,6-8H,1-2,5H2,(H2,19,23)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.80	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191544 (US9181272, 314) Show SMILES NC(=O)N1CCCc2c(Cl)c(cnc12)-c1cncc(CN2CCOCC2=O)c1 Show InChI InChI=1S/C19H20ClN5O3/c20-17-14-2-1-3-25(19(21)27)18(14)23-9-15(17)13-6-12(7-22-8-13)10-24-4-5-28-11-16(24)26/h6-9H,1-5,10-11H2,(H2,21,27)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.80	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191293 (US9181272, 63) Show SMILES CN(C)C(=O)c1ccc(cc1)-c1cncc(c1)-c1cnc2N(CCCc2c1)C(N)=O Show InChI InChI=1S/C23H23N5O2/c1-27(2)22(29)16-7-5-15(6-8-16)18-11-19(13-25-12-18)20-10-17-4-3-9-28(23(24)30)21(17)26-14-20/h5-8,10-14H,3-4,9H2,1-2H3,(H2,24,30)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.90	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191347 (US9181272, 117) Show SMILES CCc1cncc(c1)-c1cnc2N(CCCc2c1)C(N)=O Show InChI InChI=1S/C16H18N4O/c1-2-11-6-13(9-18-8-11)14-7-12-4-3-5-20(16(17)21)15(12)19-10-14/h6-10H,2-5H2,1H3,(H2,17,21)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.90	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191371 (US9181272, 141) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(c1)-c1cccc(CO)c1 Show InChI InChI=1S/C21H20N4O2/c22-21(27)25-6-2-5-16-8-19(12-24-20(16)25)18-9-17(10-23-11-18)15-4-1-3-14(7-15)13-26/h1,3-4,7-12,26H,2,5-6,13H2,(H2,22,27)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191306 (US9181272, 76) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(COC2CCOCC2)c1 Show InChI InChI=1S/C20H24N4O3/c21-20(25)24-5-1-2-15-9-17(12-23-19(15)24)16-8-14(10-22-11-16)13-27-18-3-6-26-7-4-18/h8-12,18H,1-7,13H2,(H2,21,25)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.10	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191301 (US9181272, 71) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(c1)-c1ccc(cc1)C(=O)NCCO Show InChI InChI=1S/C23H23N5O3/c24-23(31)28-8-1-2-17-10-20(14-27-21(17)28)19-11-18(12-25-13-19)15-3-5-16(6-4-15)22(30)26-7-9-29/h3-6,10-14,29H,1-2,7-9H2,(H2,24,31)(H,26,30)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.10	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191236 (US9181272, 6) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(Cl)c1 Show InChI InChI=1S/C14H13ClN4O/c15-12-5-11(6-17-8-12)10-4-9-2-1-3-19(14(16)20)13(9)18-7-10/h4-8H,1-3H2,(H2,16,20)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.30	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191365 (US9181272, 135) Show SMILES Cc1ccc(cn1)-c1cncc(c1)-c1cnc2N(CCCc2c1)C(N)=O Show InChI InChI=1S/C20H19N5O/c1-13-4-5-15(11-23-13)16-8-17(10-22-9-16)18-7-14-3-2-6-25(20(21)26)19(14)24-12-18/h4-5,7-12H,2-3,6H2,1H3,(H2,21,26)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.30	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191479 (US9181272, 249) Show SMILES CC1(C)CCN(C1)C(=O)COCc1cncc(c1)-c1cnc2N(CCCc2c1)C(N)=O Show InChI InChI=1S/C23H29N5O3/c1-23(2)5-7-27(15-23)20(29)14-31-13-16-8-18(11-25-10-16)19-9-17-4-3-6-28(22(24)30)21(17)26-12-19/h8-12H,3-7,13-15H2,1-2H3,(H2,24,30)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.30	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191249 (US9181272, 157 | US9181272, 158 | US9181272, 19) Show SMILES CC(O)c1cncc(c1)-c1cnc2N(CCCc2c1)C(N)=O Show InChI InChI=1S/C16H18N4O2/c1-10(21)12-6-13(8-18-7-12)14-5-11-3-2-4-20(16(17)22)15(11)19-9-14/h5-10,21H,2-4H2,1H3,(H2,17,22)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.60	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191505 (US9181272, 275) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(CN2CCCC2=O)c1 Show InChI InChI=1S/C19H21N5O2/c20-19(26)24-6-1-3-14-8-16(11-22-18(14)24)15-7-13(9-21-10-15)12-23-5-2-4-17(23)25/h7-11H,1-6,12H2,(H2,20,26)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.70	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191284 (US9181272, 54) Show SMILES COCc1ccncc1-c1cnc2N(CCCc2c1)C(N)=O Show InChI InChI=1S/C16H18N4O2/c1-22-10-12-4-5-18-9-14(12)13-7-11-3-2-6-20(16(17)21)15(11)19-8-13/h4-5,7-9H,2-3,6,10H2,1H3,(H2,17,21)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.80	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191300 (US9181272, 70) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(COc2ccccc2)c1 Show InChI InChI=1S/C21H20N4O2/c22-21(26)25-8-4-5-16-10-18(13-24-20(16)25)17-9-15(11-23-12-17)14-27-19-6-2-1-3-7-19/h1-3,6-7,9-13H,4-5,8,14H2,(H2,22,26)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.80	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191295 (US9181272, 65) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(c1)-c1ccc(cc1)C(N)=O Show InChI InChI=1S/C21H19N5O2/c22-19(27)14-5-3-13(4-6-14)16-9-17(11-24-10-16)18-8-15-2-1-7-26(21(23)28)20(15)25-12-18/h3-6,8-12H,1-2,7H2,(H2,22,27)(H2,23,28)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.90	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191249 (US9181272, 157 | US9181272, 158 | US9181272, 19) Show SMILES CC(O)c1cncc(c1)-c1cnc2N(CCCc2c1)C(N)=O Show InChI InChI=1S/C16H18N4O2/c1-10(21)12-6-13(8-18-7-12)14-5-11-3-2-4-20(16(17)22)15(11)19-9-14/h5-10,21H,2-4H2,1H3,(H2,17,22)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.90	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191246 (US9181272, 16) Show SMILES COCc1cncc(c1)-c1cnc2N(CCCc2c1)C(N)=O Show InChI InChI=1S/C16H18N4O2/c1-22-10-11-5-13(8-18-7-11)14-6-12-3-2-4-20(16(17)21)15(12)19-9-14/h5-9H,2-4,10H2,1H3,(H2,17,21)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.10	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191460 (US9181272, 230) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(COCC(=O)N2CCC3(CC3)CC2)c1 Show InChI InChI=1S/C24H29N5O3/c25-23(31)29-7-1-2-18-11-20(14-27-22(18)29)19-10-17(12-26-13-19)15-32-16-21(30)28-8-5-24(3-4-24)6-9-28/h10-14H,1-9,15-16H2,(H2,25,31)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.20	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191386 (US9181272, 156) Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(-c2ccc(F)cc2)c1C#N Show InChI InChI=1S/C21H16FN5O/c22-16-5-3-13(4-6-16)18-11-25-12-19(17(18)9-23)15-8-14-2-1-7-27(21(24)28)20(14)26-10-15/h3-6,8,10-12H,1-2,7H2,(H2,24,28)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.30	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
					More data for this Ligand-Target Pair

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