Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Isoform 5-HT4(E) of 5-hydroxytryptamine receptor 4 (H5-HT4(g)) (Homo sapiens (Human)) | BDBM50278564 (CHEMBL471036 | Litoxetine | US9511061, Compound A) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL MCE PC cid PC sid UniChem Patents | US Patent | 1.60E+3 | n/a | 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IXALTIS US Patent | Assay Description The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ... | US Patent US9511061 (2016) BindingDB Entry DOI: 10.7270/Q2S181FC | |||||||||||
More data for this Ligand-Target Pair |