Compile Data Set for Download or QSAR

Found 2738 hits of ic50 data for polymerid = 125,348   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548542 (WO2022093881, Ex-10.51) Show SMILES CC[C@@H]1[C@@H]([C@H]1c1ccn(C)n1)C(=O)Nc1cc2cc(N3CCN(CC3)[C@]3(C)COC[C@@H]3F)c(Cl)cc2cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548541 (WO2022093881, Ex-10.50) Show SMILES CC[C@H]1[C@H]([C@@H]1c1ccn(C)n1)C(=O)Nc1cc2cc(N3CCN(CC3)[C@@]3(C)COC[C@H]3F)c(Cl)cc2cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548545 (WO2022093881, Ex-10.54 | WO2022093881, Ex-10.64) Show SMILES C[C@H]1[C@H]([C@@H]1c1ccn(C)n1)C(=O)Nc1cc2cc(N3CCN(CC3)[C@@]3(C)COC[C@H]3O)c(Cl)cc2cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548546 (WO2022093881, Ex-10.55) Show SMILES C[C@@H]1[C@@H]([C@H]1c1ccn(C)n1)C(=O)Nc1cc2cc(N3CCN(CC3)[C@]3(C)COC[C@@H]3O)c(Cl)cc2cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548547 (WO2022093881, Ex-10.56) Show SMILES C[C@@H]1[C@@H]([C@H]1c1ccn(C)n1)C(=O)Nc1cc2cc(N3CCN(CC3)[C@@]3(C)COC[C@H]3O)c(Cl)cc2cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548548 (WO2022093881, Ex-10.57) Show SMILES C[C@H]1[C@H]([C@@H]1c1ccn(C)n1)C(=O)Nc1cc2cc(N3CCN(CC3)[C@@]3(C)COC[C@H]3F)c(C)cc2cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548549 (WO2022093881, Ex-10.58) Show SMILES C[C@@H]1[C@@H]([C@H]1c1ccn(C)n1)C(=O)Nc1cc2cc(N3CCN(CC3)[C@@]3(C)COC[C@H]3F)c(C)cc2cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548550 (WO2022093881, Ex-10.59) Show SMILES Cc1cc2cnc(NC(=O)[C@@H]3C[C@H]3c3ccn(C)n3)cc2cc1N1CCN(CC1)[C@]1(C)COC[C@@H]1F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548551 (WO2022093881, Ex-10.60) Show SMILES Cc1cc2cnc(NC(=O)[C@@H]3C[C@H]3c3ccn(C)n3)cc2cc1N1CCN(CC1)[C@@]1(C)COC[C@H]1F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548553 (WO2022093881, Ex-10.62) Show SMILES Cn1ncc([C@@H]2C[C@H]2C(=O)Nc2cc3cc(N4CCN(CC4)[C@@]4(C)COC[C@H]4F)c(Cl)cc3cn2)c1C(F)(F)F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548544 (WO2022093881, Ex-10.53 | WO2022093881, Ex-10.63) Show SMILES C[C@H]1[C@H]([C@@H]1c1ccn(C)n1)C(=O)Nc1cc2cc(N3CCN(CC3)[C@]3(C)COC[C@@H]3O)c(Cl)cc2cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548545 (WO2022093881, Ex-10.54 | WO2022093881, Ex-10.64) Show SMILES C[C@H]1[C@H]([C@@H]1c1ccn(C)n1)C(=O)Nc1cc2cc(N3CCN(CC3)[C@@]3(C)COC[C@H]3O)c(Cl)cc2cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548556 (WO2022093881, Ex-10.65) Show SMILES CC[C@H]1[C@H]([C@@H]1c1ccn(C)n1)C(=O)Nc1cc2cc(N3CCN(CC3)[C@]3(C)COC[C@@H]3O)c(Cl)cc2cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548557 (WO2022093881, Ex-10.66) Show SMILES CC[C@H]1[C@H]([C@@H]1c1ccn(C)n1)C(=O)Nc1cc2cc(N3CCN(CC3)[C@@]3(C)COC[C@H]3O)c(Cl)cc2cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548559 (WO2022093881, Ex-10.68) Show SMILES C[C@@]1(COC[C@H]1F)N1CCN(CC1)c1cc2cc(NC(=O)[C@@H]3CC[C@H]3C#N)ncc2cc1Cl Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548522 (WO2022093881, Ex-10.31 | WO2022093881, Ex-10.69) Show SMILES C[C@]1(COC[C@@H]1O)N1CCN(CC1)c1cc2cc(NC(=O)[C@@H]3C[C@@H]3C3CCOCC3)ncc2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548561 (WO2022093881, Ex-10.70) Show SMILES C[C@@]1(COC[C@H]1O)N1CCN(CC1)c1cc2cc(NC(=O)[C@@H]3C[C@@H]3C3CCOCC3)ncc2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548563 (WO2022093881, Ex-10.72) Show SMILES C[C@H]1[C@H]([C@@H]1c1ccccn1)C(=O)Nc1cc2cc(N3CCN(CC3)[C@@]3(C)COC[C@H]3F)c(Cl)cc2cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548564 (WO2022093881, Ex-10.73) Show SMILES Cc1cc2cnc(NC(=O)[C@@H]3CC33CC3)cc2cc1N1CCN(CC1)[C@]1(C)COC[C@@H]1F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548565 (WO2022093881, Ex-10.74) Show SMILES Cc1cc2cnc(NC(=O)[C@@H]3CC33CC3)cc2cc1N1CCN(CC1)[C@@]1(C)COC[C@H]1F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548567 (WO2022093881, Ex-10.76) Show SMILES C[C@@]1(COC[C@H]1F)N1CCN(CC1)c1cc2cc(NC(=O)[C@@H]3C[C@H]3C(F)F)ncc2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548568 (WO2022093881, Ex-10.77) Show SMILES C[C@]1(COC[C@@H]1F)N1CCN(CC1)c1cc2cc(NC(=O)[C@H]3C[C@@H]3C(F)F)ncc2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548569 (WO2022093881, Ex-10.78) Show SMILES C[C@@]1(COC[C@H]1F)N1CCN(CC1)c1cc2cc(NC(=O)[C@H]3C[C@@H]3C(F)F)ncc2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548570 (WO2022093881, Ex-10.79) Show SMILES C[C@]1(COC[C@@H]1F)N1CCN(CC1)c1cc2cc(NC(=O)[C@@H]3CC33CC3)ncc2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548572 (WO2022093881, Ex-10.81) Show SMILES C[C@@]1(C[C@H]1C(=O)Nc1cc2cc(N3CCN(CC3)[C@]3(C)COC[C@@H]3O)c(Cl)cc2cn1)C1CCOC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548576 (WO2022093881, Ex-10.85) Show SMILES C[C@@]1(C[C@H]1C(=O)Nc1cc2cc(N3CCN(CC3)[C@@]3(C)COC[C@H]3O)c(Cl)cc2cn1)C1CCOC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548577 (WO2022093881, Ex-10.86) Show SMILES C[C@@]1(C[C@@H]1C(=O)Nc1cc2cc(N3CCN(CC3)[C@@]3(C)COC[C@H]3O)c(Cl)cc2cn1)C1CCOC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548578 (WO2022093881, Ex-10.87) Show SMILES C[C@]1(C[C@H]1C(=O)Nc1cc2cc(N3CCN(CC3)[C@@]3(C)COC[C@H]3O)c(Cl)cc2cn1)C1CCOC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548580 (WO2022093881, Ex-10.89) Show SMILES CC[C@H]1[C@H]([C@@H]1c1ccccn1)C(=O)Nc1cc2cc(N3CCN(CC3)[C@@]3(C)COC[C@@H]3F)c(Cl)cc2cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548582 (WO2022093881, Ex-10.91) Show SMILES CC1(C)[C@H]([C@@H]1C(=O)Nc1cc2cc(N3CCN(CC3)[C@]3(C)COC[C@@H]3O)c(Cl)cc2cn1)C1CCCCO1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548588 (WO2022093881, Ex-11.1) Show SMILES C[C@]1(C[C@H]1C(=O)Nc1cc2cc(N3CCN(CC3)[C@@]3(C)COC[C@H]3O)c(Cl)cc2cn1)c1ccccn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548590 (WO2022093881, Ex-11.3) Show SMILES C[C@H]1[C@H]([C@@H]1c1ccccn1)C(=O)Nc1cc2cc(N3CCN(CC3)[C@]3(C)COC[C@@H]3O)c(Cl)cc2cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548592 (WO2022093881, Ex-11.5) Show SMILES C[C@]1(COC[C@@H]1O)N1CCN(CC1)c1cc2cc(NC(=O)[C@@H]3CC[C@H]3c3ccccn3)ncc2cc1Cl Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548597 (WO2022093881, Ex-14.2) Show SMILES C[C@H]1CN(CCN1c1cc2cc(NC(=O)[C@@H]3CC33CCOCC3)ncc2cc1Cl)[C@]1(C)COC[C@@H]1O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548599 (WO2022093881, Ex-15.2) Show SMILES C[C@H]1CN(CCN1c1cc2cc(NC(=O)[C@@H]3CC33CCOCC3)ncc2cc1C)[C@]1(C)COC[C@@H]1O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548601 (WO2022093881, Ex-16.2) Show SMILES Cn1ncc(n1)C1CC1C(=O)Nc1cc2cc(N3CCN(CC3)[C@@]3(C)COC[C@H]3O)c(Cl)cc2cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548602 (WO2022093881, Ex-17.1) Show SMILES Cn1ncc(n1)C1CC1C(=O)Nc1cc2cc(N3CCN(CC3)[C@]3(C)COC[C@]3(C)O)c(Cl)cc2cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548446 (WO2022093881, Ex-5.17) Show SMILES Clc1cc2cnc(NC(=O)[C@@H]3C[C@H]3c3cncnc3)cc2cc1N1CCC(CC1)C#N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548462 (WO2022093881, Ex-6.13) Show SMILES Cc1cc2cnc(NC(=O)[C@@H]3C[C@H]3c3ccccn3)cc2cc1N1CCN(CC1)[C@]1(C)COC[C@@H]1F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548477 (WO2022093881, Ex-9.7) Show SMILES C[C@@H]1[C@H]([C@@H]1c1cnn(C)c1)C(=O)Nc1cc2cc(N3CCN(CC3)C3(C)CCOC3)c(Cl)cc2cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548480 (WO2022093881, Ex-9.10) Show SMILES CC[C@H]1[C@@H]([C@H]1c1cnn(C)c1)C(=O)Nc1cc2cc(N3CCN(CC3)C3(C)CCOC3)c(Cl)cc2cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548482 (WO2022093881, Ex-9.12) Show SMILES C[C@H]1[C@H](C1c1cnn(C)c1)C(=O)Nc1cc2cc(N3CCN(CC3)C3(C)CCOC3)c(C)cc2cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548484 (WO2022093881, Ex-9.14) Show SMILES C[C@H]1[C@@H](C1c1cnn(C)c1)C(=O)Nc1cc2cc(N3CCN(CC3)C3(C)CCOC3)c(C)cc2cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548489 (WO2022093881, Ex-9.19) Show SMILES Cc1cc2cnc(NC(=O)C3CC3c3ccccn3)cc2cc1N1CCN(CC1)C1(C)COCC1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548490 (WO2022093881, Ex-9.20) Show SMILES CCC1C(C1c1ccccn1)C(=O)Nc1cc2cc(N3CCN(CC3)C3(C)COCC3F)c(C)cc2cn1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548491 (WO2022093881, Ex-9.21) Show SMILES Cc1cc2cnc(NC(=O)C3CC3c3ccccn3)cc2cc1N1CCN(CC1)C1(C)CCOC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548503 (WO2022093881, Ex-10.12) Show SMILES CCO[C@@H]1C[C@@H]1C(=O)Nc1cc2cc(N3CCN(CC3)[C@]3(C)COC[C@@H]3O)c(Cl)cc2cn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548504 (WO2022093881, Ex-10.13) Show SMILES C[C@]1(COC[C@@H]1O)N1CCN(CC1)c1cc2cc(NC(=O)[C@H]3C[C@H]3c3cccs3)ncc2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548515 (WO2022093881, Ex-10.24) Show SMILES CCO[C@H]1C[C@@]2(C[C@@H]2C(=O)Nc2cc3cc(N4CCN(CC4)[C@]4(C)COC[C@@H]4F)c(Cl)cc3cn2)C1 |wU:22.24,wD:3.2,5.5,7.8,27.30,(-8.76,-4.17,;-7.43,-3.4,;-7.43,-1.86,;-6.09,-1.09,;-4.61,-1.49,;-4.21,,;-3.44,1.33,;-2.67,,;-1.33,-.77,;-1.33,-2.31,;;1.33,-.77,;2.67,,;4,-.77,;5.33,,;6.67,-.77,;8,,;8,1.54,;9.34,2.31,;10.67,1.54,;10.67,,;9.34,-.77,;12,2.31,;12.63,.9,;11.1,3.56,;12,4.8,;13.47,4.33,;13.47,2.79,;14.71,1.88,;6.67,-2.31,;8,-3.08,;5.33,-3.08,;4,-2.31,;2.67,-3.08,;1.33,-2.31,;-5.69,.4,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM548521 (WO2022093881, Ex-10.30) Show SMILES C[C@]1(COC[C@@H]1O)N1CCN(CC1)c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3ccco3)ncc2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022093881	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q81H9H
					More data for this Ligand-Target Pair

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