Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20242 (4-[(2S)-2-{[(2S)-1-[(1R,2S,5S)-2-{[(1S)-1-(benzylc...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 125 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas at Houston | Assay Description Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe... | J Med Chem 48: 6661-70 (2005) Article DOI: 10.1021/jm050513m BindingDB Entry DOI: 10.7270/Q2TH8JZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20193 (1, Ac-pTyr-Leu-Pro-Gln-Thr-Val-NH2 | 4-[(2S)-2-{[(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | 7.8 | 22 |
The University of Texas at Houston | Assay Description His10-Stat3 was expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with 32P... | Bioorg Med Chem Lett 13: 633-6 (2003) Article DOI: 10.1016/S0960-894X(02)01050-8 BindingDB Entry DOI: 10.7270/Q2K35RX1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20211 (18, Ac-pTyr-Leu-cis-3,4-methanoPro-Gln-Thr-NH2-1 |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 265 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The University of Texas at Houston | Assay Description Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe... | J Med Chem 48: 6661-70 (2005) Article DOI: 10.1021/jm050513m BindingDB Entry DOI: 10.7270/Q2TH8JZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20200 (4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 276 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The University of Texas at Houston | Assay Description Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe... | J Med Chem 48: 6661-70 (2005) Article DOI: 10.1021/jm050513m BindingDB Entry DOI: 10.7270/Q2TH8JZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20193 (1, Ac-pTyr-Leu-Pro-Gln-Thr-Val-NH2 | 4-[(2S)-2-{[(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 290 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The University of Texas at Houston | Assay Description Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe... | J Med Chem 48: 6661-70 (2005) Article DOI: 10.1021/jm050513m BindingDB Entry DOI: 10.7270/Q2TH8JZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM549118 (BDBM50556884 | US11299480, Example 53) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20253 (LIFR (1001) derived peptide, 9 | Y(p)KPQMH) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | 7.8 | 22 |
The University of Texas at Houston | Assay Description His10-Stat3 was expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with 32P... | Bioorg Med Chem Lett 13: 633-6 (2003) Article DOI: 10.1016/S0960-894X(02)01050-8 BindingDB Entry DOI: 10.7270/Q2K35RX1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20266 (4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | 7.8 | 22 |
The University of Texas at Houston | Assay Description His10-Stat3 was expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with 32P... | Bioorg Med Chem Lett 13: 633-6 (2003) Article DOI: 10.1016/S0960-894X(02)01050-8 BindingDB Entry DOI: 10.7270/Q2K35RX1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20233 (4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-1-(benzylcarbamo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 409 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas at Houston | Assay Description Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe... | J Med Chem 48: 6661-70 (2005) Article DOI: 10.1021/jm050513m BindingDB Entry DOI: 10.7270/Q2TH8JZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM50556886 (CHEMBL4753422) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM549121 (BDBM50556885 | US11299480, Example 133) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20210 (17, Ac-pTyr-Leu-4-hydroxy-Pro-Gln-Thr-NH2 | 4-[(2S...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 484 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The University of Texas at Houston | Assay Description Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe... | J Med Chem 48: 6661-70 (2005) Article DOI: 10.1021/jm050513m BindingDB Entry DOI: 10.7270/Q2TH8JZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20198 (4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 497 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The University of Texas at Houston | Assay Description Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe... | J Med Chem 48: 6661-70 (2005) Article DOI: 10.1021/jm050513m BindingDB Entry DOI: 10.7270/Q2TH8JZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM549075 (BDBM50556877 | US11299480, Example 34) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM50556879 (CHEMBL4752153) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM50556876 (CHEMBL4743282) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 580 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20234 (4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 596 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas at Houston | Assay Description Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe... | J Med Chem 48: 6661-70 (2005) Article DOI: 10.1021/jm050513m BindingDB Entry DOI: 10.7270/Q2TH8JZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20195 (2, Ac-pTyr-Leu-Pro-Gln-Thr-NH2 | 4-[(2S)-2-{[(2S)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | 7.8 | 22 |
The University of Texas at Houston | Assay Description His10-Stat3 was expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with 32P... | Bioorg Med Chem Lett 13: 633-6 (2003) Article DOI: 10.1016/S0960-894X(02)01050-8 BindingDB Entry DOI: 10.7270/Q2K35RX1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM549103 (BDBM50556888 | US11299480, Example 125) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM50556882 (CHEMBL4786885) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 660 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM50556878 (CHEMBL4742343) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 660 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM50556887 (CHEMBL4799226) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM50556875 (CHEMBL4754054 | US11299480, Example 80) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20205 (12, Ac-pTyr-Nle-Pro-Gln-Thr-NH2 | 4-[(2S)-2-{[(2S)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 717 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The University of Texas at Houston | Assay Description Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe... | J Med Chem 48: 6661-70 (2005) Article DOI: 10.1021/jm050513m BindingDB Entry DOI: 10.7270/Q2TH8JZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20195 (2, Ac-pTyr-Leu-Pro-Gln-Thr-NH2 | 4-[(2S)-2-{[(2S)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 739 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The University of Texas at Houston | Assay Description Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe... | J Med Chem 48: 6661-70 (2005) Article DOI: 10.1021/jm050513m BindingDB Entry DOI: 10.7270/Q2TH8JZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20236 ((2S)-4-carbamoyl-2-{[(2S)-1-[(2S)-2-[(2S)-2-acetam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 748 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas at Houston | Assay Description Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe... | J Med Chem 48: 6661-70 (2005) Article DOI: 10.1021/jm050513m BindingDB Entry DOI: 10.7270/Q2TH8JZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20199 (4-[(2S)-2-{[(benzyloxy)carbonyl]amino}-2-{[(2S)-1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 750 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The University of Texas at Houston | Assay Description Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe... | J Med Chem 48: 6661-70 (2005) Article DOI: 10.1021/jm050513m BindingDB Entry DOI: 10.7270/Q2TH8JZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM50556897 (CHEMBL4743428) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM50556889 (CHEMBL4788858) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20265 (4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | 7.8 | 22 |
The University of Texas at Houston | Assay Description His10-Stat3 was expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with 32P... | Bioorg Med Chem Lett 13: 633-6 (2003) Article DOI: 10.1016/S0960-894X(02)01050-8 BindingDB Entry DOI: 10.7270/Q2K35RX1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20235 (4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 801 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas at Houston | Assay Description Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe... | J Med Chem 48: 6661-70 (2005) Article DOI: 10.1021/jm050513m BindingDB Entry DOI: 10.7270/Q2TH8JZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM549310 (BDBM50556881 | US11299480, Example 64) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 810 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20197 (4, Benzoyl-pTyr-Leu -Pro-Gln-Thr-NH2 | 4-[(2S)-2-{...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 814 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The University of Texas at Houston | Assay Description Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe... | J Med Chem 48: 6661-70 (2005) Article DOI: 10.1021/jm050513m BindingDB Entry DOI: 10.7270/Q2TH8JZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20196 (3, Ac-pTyr-Leu-Pro-Gln-NH2 | 4-[(2S)-2-{[(2S)-1-[(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 856 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The University of Texas at Houston | Assay Description Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe... | J Med Chem 48: 6661-70 (2005) Article DOI: 10.1021/jm050513m BindingDB Entry DOI: 10.7270/Q2TH8JZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM549083 (BDBM50556898 | US11299480, Example 116) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20232 (39, Ac-pTyr-Leu-Pro-Gln-NHMe | 4-[(2S)-2-{[(2S)-1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 882 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas at Houston | Assay Description Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe... | J Med Chem 48: 6661-70 (2005) Article DOI: 10.1021/jm050513m BindingDB Entry DOI: 10.7270/Q2TH8JZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM50556883 (CHEMBL4758974) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20204 (11, Ac-pTyr-Cha-Pro-Gln-Thr-NH2 | 4-[(2S)-2-{[(2S)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 910 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The University of Texas at Houston | Assay Description Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe... | J Med Chem 48: 6661-70 (2005) Article DOI: 10.1021/jm050513m BindingDB Entry DOI: 10.7270/Q2TH8JZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20254 (4-[(2S)-2-{[(2S)-5-carbamimidamido-1-[(2S)-2-{[(1S...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | 7.8 | 22 |
The University of Texas at Houston | Assay Description His10-Stat3 was expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with 32P... | Bioorg Med Chem Lett 13: 633-6 (2003) Article DOI: 10.1016/S0960-894X(02)01050-8 BindingDB Entry DOI: 10.7270/Q2K35RX1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20196 (3, Ac-pTyr-Leu-Pro-Gln-NH2 | 4-[(2S)-2-{[(2S)-1-[(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | 7.8 | 22 |
The University of Texas at Houston | Assay Description His10-Stat3 was expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with 32P... | Bioorg Med Chem Lett 13: 633-6 (2003) Article DOI: 10.1016/S0960-894X(02)01050-8 BindingDB Entry DOI: 10.7270/Q2K35RX1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM549058 (BDBM50556905 | US11299480, Example 107) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20202 (4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.07E+3 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The University of Texas at Houston | Assay Description Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe... | J Med Chem 48: 6661-70 (2005) Article DOI: 10.1021/jm050513m BindingDB Entry DOI: 10.7270/Q2TH8JZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM50556895 (CHEMBL4760561) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM549099 (BDBM50556892 | US11299480, Example 123) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM50556873 (CHEMBL4793287) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM50556904 (CHEMBL4763364) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM549101 (BDBM50556899 | US11299480, Example 124) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20241 (4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas at Houston | Assay Description Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe... | J Med Chem 48: 6661-70 (2005) Article DOI: 10.1021/jm050513m BindingDB Entry DOI: 10.7270/Q2TH8JZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM20214 (21, Ac-pTyr-Leu-Pip-Gln-Thr-NH2 | 4-[(2S)-2-{[(2S)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.24E+3 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The University of Texas at Houston | Assay Description Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe... | J Med Chem 48: 6661-70 (2005) Article DOI: 10.1021/jm050513m BindingDB Entry DOI: 10.7270/Q2TH8JZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Mus musculus (mouse)) | BDBM50556880 (CHEMBL4796668 | US11299480, Example 63) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01705 BindingDB Entry DOI: 10.7270/Q2Z89H31 | |||||||||||
More data for this Ligand-Target Pair |
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