Compile Data Set for Download or QSAR

Found 93 hits of ic50 data for polymerid = 3360,8370   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198857 (BDBM198884 | US9221797, 20) Show SMILES COCCNC(C)(C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:26| Show InChI InChI=1S/C25H33N5O2/c1-24(2)10-8-17(9-11-24)20-14-18(25(3,4)28-12-13-32-5)6-7-21(20)30-23(31)22-27-16-19(15-26)29-22/h6-8,14,16,28H,9-13H2,1-5H3,(H,27,29)(H,30,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.440	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198857 (BDBM198884 | US9221797, 20) Show SMILES COCCNC(C)(C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:26| Show InChI InChI=1S/C25H33N5O2/c1-24(2)10-8-17(9-11-24)20-14-18(25(3,4)28-12-13-32-5)6-7-21(20)30-23(31)22-27-16-19(15-26)29-22/h6-8,14,16,28H,9-13H2,1-5H3,(H,27,29)(H,30,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.510	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198873 (US9221797, 45) Show SMILES CC1CCCC(=C1C)c1cc(ccc1NC(=O)c1ncc([nH]1)C#N)C(C)(C)N1CCCC1 |c:5| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198904 (US9221797, 147) Show SMILES COCCNCC(C)(C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:27| Show InChI InChI=1S/C26H35N5O2/c1-25(2)10-8-18(9-11-25)21-14-19(26(3,4)17-28-12-13-33-5)6-7-22(21)31-24(32)23-29-16-20(15-27)30-23/h6-8,14,16,28H,9-13,17H2,1-5H3,(H,29,30)(H,31,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.640	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198891 (US9221797, 76) Show SMILES CC(=O)NCCNC(C)(C)c1ccc(C(=O)NOC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:31| Show InChI InChI=1S/C27H34N6O4/c1-17(34)29-12-13-31-27(4,5)19-6-7-21(22(14-19)18-8-10-26(2,3)11-9-18)24(35)33-37-25(36)23-30-16-20(15-28)32-23/h6-8,14,16,31H,9-13H2,1-5H3,(H,29,34)(H,30,32)(H,33,35)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.680	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198878 (BDBM198879 | US9221797, 62) Show SMILES CC(C)(N1CCN(CCO)CC1)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:31| Show InChI InChI=1S/C28H38N6O2/c1-27(2)9-7-20(8-10-27)23-17-21(28(3,4)34-13-11-33(12-14-34)15-16-35)5-6-24(23)32-26(36)25-30-19-22(18-29)31-25/h5-7,17,19,35H,8-16H2,1-4H3,(H,30,31)(H,32,36)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.690	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198907 (US9221797, 150) Show SMILES CC1(C)CCC(=CC1)c1cc(CN2CCN(CCO)CC2)ccc1NC(=O)c1nc(c[nH]1)C#N |c:5| Show InChI InChI=1S/C26H34N6O2/c1-26(2)7-5-20(6-8-26)22-15-19(18-32-11-9-31(10-12-32)13-14-33)3-4-23(22)30-25(34)24-28-17-21(16-27)29-24/h3-5,15,17,33H,6-14,18H2,1-2H3,(H,28,29)(H,30,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.75	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM119039 (CHEMBL3086316 | US8674100, 52 | US9221797, 52) Show SMILES CN(C)CCOC(C)(C)c1ccc(NC(=O)c2ncc([nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:27| Show InChI InChI=1S/C26H35N5O2/c1-25(2)11-9-18(10-12-25)21-15-19(26(3,4)33-14-13-31(5)6)7-8-22(21)30-24(32)23-28-17-20(16-27)29-23/h7-9,15,17H,10-14H2,1-6H3,(H,28,29)(H,30,32)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM119043 (CHEMBL3085978 | US8674100, 60 | US9221797, 60) Show SMILES CC1(C)CCC(=CC1)c1cc(CCN2CCOCC2)ccc1NC(=O)c1ncc([nH]1)C#N |c:5| Show InChI InChI=1S/C25H31N5O2/c1-25(2)8-5-19(6-9-25)21-15-18(7-10-30-11-13-32-14-12-30)3-4-22(21)29-24(31)23-27-17-20(16-26)28-23/h3-5,15,17H,6-14H2,1-2H3,(H,27,28)(H,29,31)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198908 (US9221797, 151) Show SMILES CC1(C)CCC(=CC1)c1cc(CN2CCNCC2)ccc1NC(=O)c1nc(c[nH]1)C#N |c:5| Show InChI InChI=1S/C24H30N6O/c1-24(2)7-5-18(6-8-24)20-13-17(16-30-11-9-26-10-12-30)3-4-21(20)29-23(31)22-27-15-19(14-25)28-22/h3-5,13,15,26H,6-12,16H2,1-2H3,(H,27,28)(H,29,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.820	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198878 (BDBM198879 | US9221797, 62) Show SMILES CC(C)(N1CCN(CCO)CC1)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:31| Show InChI InChI=1S/C28H38N6O2/c1-27(2)9-7-20(8-10-27)23-17-21(28(3,4)34-13-11-33(12-14-34)15-16-35)5-6-24(23)32-26(36)25-30-19-22(18-29)31-25/h5-7,17,19,35H,8-16H2,1-4H3,(H,30,31)(H,32,36)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.880	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198880 (US9221797, 64) Show SMILES CC(C)(N1CCN(CC(O)=O)CC1)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:32| Show InChI InChI=1S/C28H36N6O3/c1-27(2)9-7-19(8-10-27)22-15-20(28(3,4)34-13-11-33(12-14-34)18-24(35)36)5-6-23(22)32-26(37)25-30-17-21(16-29)31-25/h5-7,15,17H,8-14,18H2,1-4H3,(H,30,31)(H,32,37)(H,35,36)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.930	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198859 (US9221797, 22) Show SMILES CC(C)(N1CCOCC1)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:28| Show InChI InChI=1S/C26H33N5O2/c1-25(2)9-7-18(8-10-25)21-15-19(26(3,4)31-11-13-33-14-12-31)5-6-22(21)30-24(32)23-28-17-20(16-27)29-23/h5-7,15,17H,8-14H2,1-4H3,(H,28,29)(H,30,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.940	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198852 (US9221797, 15) Show SMILES CC(C)(N1CCS(=O)CC1)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:29| Show InChI InChI=1S/C26H33N5O2S/c1-25(2)9-7-18(8-10-25)21-15-19(26(3,4)31-11-13-34(33)14-12-31)5-6-22(21)30-24(32)23-28-17-20(16-27)29-23/h5-7,15,17H,8-14H2,1-4H3,(H,28,29)(H,30,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198861 (US9221797, 24) Show SMILES CC(C)(NCCN1CCOCC1)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:31| Show InChI InChI=1S/C28H38N6O2/c1-27(2)9-7-20(8-10-27)23-17-21(28(3,4)31-11-12-34-13-15-36-16-14-34)5-6-24(23)33-26(35)25-30-19-22(18-29)32-25/h5-7,17,19,31H,8-16H2,1-4H3,(H,30,32)(H,33,35)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198894 (US9221797, 80) Show SMILES CC(C)(OCCN1CCCC1)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:30| Show InChI InChI=1S/C28H37N5O2/c1-27(2)11-9-20(10-12-27)23-17-21(28(3,4)35-16-15-33-13-5-6-14-33)7-8-24(23)32-26(34)25-30-19-22(18-29)31-25/h7-9,17,19H,5-6,10-16H2,1-4H3,(H,30,31)(H,32,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198895 (US9221797, 138) Show SMILES CSCCNCC(C)(C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:27| Show InChI InChI=1S/C26H35N5OS/c1-25(2)10-8-18(9-11-25)21-14-19(26(3,4)17-28-12-13-33-5)6-7-22(21)31-24(32)23-29-16-20(15-27)30-23/h6-8,14,16,28H,9-13,17H2,1-5H3,(H,29,30)(H,31,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198882 (US9221797, 67) Show SMILES COCCNCC(=C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCCCC1 |t:26| Show InChI InChI=1S/C23H27N5O2/c1-16(14-25-10-11-30-2)18-8-9-21(20(12-18)17-6-4-3-5-7-17)28-23(29)22-26-15-19(13-24)27-22/h6,8-9,12,15,25H,1,3-5,7,10-11,14H2,2H3,(H,26,27)(H,28,29)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198892 (US9221797, 77) Show SMILES COCCN1CCN(CC1)C(C)(C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:32| Show InChI InChI=1S/C29H40N6O2/c1-28(2)10-8-21(9-11-28)24-18-22(29(3,4)35-14-12-34(13-15-35)16-17-37-5)6-7-25(24)33-27(36)26-31-20-23(19-30)32-26/h6-8,18,20H,9-17H2,1-5H3,(H,31,32)(H,33,36)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198854 (US9221797, 17) Show SMILES CSCCNC(C)(C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:26| Show InChI InChI=1S/C25H33N5OS/c1-24(2)10-8-17(9-11-24)20-14-18(25(3,4)28-12-13-32-5)6-7-21(20)30-23(31)22-27-16-19(15-26)29-22/h6-8,14,16,28H,9-13H2,1-5H3,(H,27,29)(H,30,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM50443132 (CHEMBL3086175 | US9221797, 42) Show SMILES O=C(Nc1ccc(CCN2CCOCC2)cc1C1=CCCCC1)c1ncc([nH]1)C#N |t:19| Show InChI InChI=1S/C23H27N5O2/c24-15-19-16-25-22(26-19)23(29)27-21-7-6-17(8-9-28-10-12-30-13-11-28)14-20(21)18-4-2-1-3-5-18/h4,6-7,14,16H,1-3,5,8-13H2,(H,25,26)(H,27,29)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.43	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198889 (US9221797, 74) Show SMILES CCN1CCN(CC1)C(C)(C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:30| Show InChI InChI=1S/C28H38N6O/c1-6-33-13-15-34(16-14-33)28(4,5)21-7-8-24(32-26(35)25-30-19-22(18-29)31-25)23(17-21)20-9-11-27(2,3)12-10-20/h7-9,17,19H,6,10-16H2,1-5H3,(H,30,31)(H,32,35)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198874 (US9221797, 47) Show SMILES COC[C@H](O)Cc1ccc(NC(=O)c2ncc([nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:24| Show InChI InChI=1S/C23H28N4O3/c1-23(2)8-6-16(7-9-23)19-11-15(10-18(28)14-30-3)4-5-20(19)27-22(29)21-25-13-17(12-24)26-21/h4-6,11,13,18,28H,7-10,14H2,1-3H3,(H,25,26)(H,27,29)/t18-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198906 (US9221797, 149) Show SMILES CC1CCCC(=C1C)c1cc(ccc1NC(=O)c1nc(c[nH]1)C#N)C(C)(C)N1CCCCC1 |c:5| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198883 (US9221797, 68) Show SMILES CNCC(=C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCCCC1 |t:23| Show InChI InChI=1S/C21H23N5O/c1-14(12-23-2)16-8-9-19(18(10-16)15-6-4-3-5-7-15)26-21(27)20-24-13-17(11-22)25-20/h6,8-10,13,23H,1,3-5,7,12H2,2H3,(H,24,25)(H,26,27)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198896 (US9221797, 139) Show SMILES CC(C)(CNCCS(C)(=O)=O)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:29| Show InChI InChI=1S/C26H35N5O3S/c1-25(2)10-8-18(9-11-25)21-14-19(26(3,4)17-28-12-13-35(5,33)34)6-7-22(21)31-24(32)23-29-16-20(15-27)30-23/h6-8,14,16,28H,9-13,17H2,1-5H3,(H,29,30)(H,31,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198858 (US9221797, 21) Show SMILES COCCN(C)C(C)(C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:27| Show InChI InChI=1S/C26H35N5O2/c1-25(2)11-9-18(10-12-25)21-15-19(26(3,4)31(5)13-14-33-6)7-8-22(21)30-24(32)23-28-17-20(16-27)29-23/h7-9,15,17H,10-14H2,1-6H3,(H,28,29)(H,30,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198847 (US9221797, 10) Show SMILES CC1(C)CCC(=CC1)c1cc(CCC(N)=O)ccc1NC(=O)c1nc(c[nH]1)C#N |c:5| Show InChI InChI=1S/C22H25N5O2/c1-22(2)9-7-15(8-10-22)17-11-14(4-6-19(24)28)3-5-18(17)27-21(29)20-25-13-16(12-23)26-20/h3,5,7,11,13H,4,6,8-10H2,1-2H3,(H2,24,28)(H,25,26)(H,27,29)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198905 (US9221797, 148) Show SMILES CC(N1CC(C)NC(C)C1)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:29| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198890 (US9221797, 75) Show SMILES CC(=O)N1CCN(CC1)C(C)(C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:31| Show InChI InChI=1S/C28H36N6O2/c1-19(35)33-12-14-34(15-13-33)28(4,5)21-6-7-24(32-26(36)25-30-18-22(17-29)31-25)23(16-21)20-8-10-27(2,3)11-9-20/h6-8,16,18H,9-15H2,1-5H3,(H,30,31)(H,32,36)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198855 (US9221797, 18) Show SMILES CC(C)(NCCS(C)(=O)=O)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:28| Show InChI InChI=1S/C25H33N5O3S/c1-24(2)10-8-17(9-11-24)20-14-18(25(3,4)28-12-13-34(5,32)33)6-7-21(20)30-23(31)22-27-16-19(15-26)29-22/h6-8,14,16,28H,9-13H2,1-5H3,(H,27,29)(H,30,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198877 (US9221797, 61) Show SMILES CC(C)(OCCN1CCOCC1)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:31| Show InChI InChI=1S/C28H37N5O3/c1-27(2)9-7-20(8-10-27)23-17-21(28(3,4)36-16-13-33-11-14-35-15-12-33)5-6-24(23)32-26(34)25-30-19-22(18-29)31-25/h5-7,17,19H,8-16H2,1-4H3,(H,30,31)(H,32,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198893 (US9221797, 79) Show SMILES CCOC(=O)CN1CCN(CC1)C(C)(C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:34| Show InChI InChI=1S/C30H40N6O3/c1-6-39-26(37)20-35-13-15-36(16-14-35)30(4,5)22-7-8-25(34-28(38)27-32-19-23(18-31)33-27)24(17-22)21-9-11-29(2,3)12-10-21/h7-9,17,19H,6,10-16,20H2,1-5H3,(H,32,33)(H,34,38)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198903 (US9221797, 146) Show SMILES CC(C)(CN1CCN(CCO)CC1)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:32| Show InChI InChI=1S/C29H40N6O2/c1-28(2)9-7-21(8-10-28)24-17-22(29(3,4)20-35-13-11-34(12-14-35)15-16-36)5-6-25(24)33-27(37)26-31-19-23(18-30)32-26/h5-7,17,19,36H,8-16,20H2,1-4H3,(H,31,32)(H,33,37)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM119041 (CHEMBL3086172 | US8674100, 54 | US9221797, 54) Show SMILES CC1(C)CCC(=CC1)c1cc(CC(=O)NCCCO)ccc1NC(=O)c1ncc([nH]1)C#N |c:5| Show InChI InChI=1S/C24H29N5O3/c1-24(2)8-6-17(7-9-24)19-12-16(13-21(31)26-10-3-11-30)4-5-20(19)29-23(32)22-27-15-18(14-25)28-22/h4-6,12,15,30H,3,7-11,13H2,1-2H3,(H,26,31)(H,27,28)(H,29,32)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM119033 (US8674100, 46 | US9221797, 46) Show SMILES CC1(C)CCC(=CC1)c1cc(ccc1NC(=O)c1ncc([nH]1)C#N)C(O)C(O)=O |c:5| Show InChI InChI=1S/C21H22N4O4/c1-21(2)7-5-12(6-8-21)15-9-13(17(26)20(28)29)3-4-16(15)25-19(27)18-23-11-14(10-22)24-18/h3-5,9,11,17,26H,6-8H2,1-2H3,(H,23,24)(H,25,27)(H,28,29)	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198858 (US9221797, 21) Show SMILES COCCN(C)C(C)(C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:27| Show InChI InChI=1S/C26H35N5O2/c1-25(2)11-9-18(10-12-25)21-15-19(26(3,4)31(5)13-14-33-6)7-8-22(21)30-24(32)23-28-17-20(16-27)29-23/h7-9,15,17H,10-14H2,1-6H3,(H,28,29)(H,30,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198868 (US9221797, 31) Show SMILES CNS(=O)(=O)CCc1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:25| Show InChI InChI=1S/C22H27N5O3S/c1-22(2)9-6-16(7-10-22)18-12-15(8-11-31(29,30)24-3)4-5-19(18)27-21(28)20-25-14-17(13-23)26-20/h4-6,12,14,24H,7-11H2,1-3H3,(H,25,26)(H,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198844 (US9221797, 7) Show SMILES NC(=O)CCc1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCCCC1 |t:23| Show InChI InChI=1S/C20H21N5O2/c21-11-15-12-23-19(24-15)20(27)25-17-8-6-13(7-9-18(22)26)10-16(17)14-4-2-1-3-5-14/h4,6,8,10,12H,1-3,5,7,9H2,(H2,22,26)(H,23,24)(H,25,27)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198876 (US9221797, 53) Show SMILES CN(C)CCNC(=O)Cc1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:27| Show InChI InChI=1S/C25H32N6O2/c1-25(2)9-7-18(8-10-25)20-13-17(14-22(32)27-11-12-31(3)4)5-6-21(20)30-24(33)23-28-16-19(15-26)29-23/h5-7,13,16H,8-12,14H2,1-4H3,(H,27,32)(H,28,29)(H,30,33)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198860 (US9221797, 23) Show SMILES CN1CCN(CC1)C(C)(C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:29| Show InChI InChI=1S/C27H36N6O/c1-26(2)10-8-19(9-11-26)22-16-20(27(3,4)33-14-12-32(5)13-15-33)6-7-23(22)31-25(34)24-29-18-21(17-28)30-24/h6-8,16,18H,9-15H2,1-5H3,(H,29,30)(H,31,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198866 (US9221797, 29) Show SMILES CN(C)S(=O)(=O)CCc1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:26| Show InChI InChI=1S/C23H29N5O3S/c1-23(2)10-7-17(8-11-23)19-13-16(9-12-32(30,31)28(3)4)5-6-20(19)27-22(29)21-25-15-18(14-24)26-21/h5-7,13,15H,8-12H2,1-4H3,(H,25,26)(H,27,29)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198863 (US9221797, 26) Show SMILES O=C(Nc1ccc(CCS(=O)(=O)N2CCOCC2)cc1C1=CCCCC1)c1nc(c[nH]1)C#N |t:22| Show InChI InChI=1S/C23H27N5O4S/c24-15-19-16-25-22(26-19)23(29)27-21-7-6-17(14-20(21)18-4-2-1-3-5-18)8-13-33(30,31)28-9-11-32-12-10-28/h4,6-7,14,16H,1-3,5,8-13H2,(H,25,26)(H,27,29)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.20	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198853 (US9221797, 16) Show SMILES CC(C)(N1CCS(=O)(=O)CC1)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:30| Show InChI InChI=1S/C26H33N5O3S/c1-25(2)9-7-18(8-10-25)21-15-19(26(3,4)31-11-13-35(33,34)14-12-31)5-6-22(21)30-24(32)23-28-17-20(16-27)29-23/h5-7,15,17H,8-14H2,1-4H3,(H,28,29)(H,30,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198902 (US9221797, 145) Show SMILES CC(C)(CN1CCS(=O)(=O)CC1)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:31| Show InChI InChI=1S/C27H35N5O3S/c1-26(2)9-7-19(8-10-26)22-15-20(27(3,4)18-32-11-13-36(34,35)14-12-32)5-6-23(22)31-25(33)24-29-17-21(16-28)30-24/h5-7,15,17H,8-14,18H2,1-4H3,(H,29,30)(H,31,33)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198863 (US9221797, 26) Show SMILES O=C(Nc1ccc(CCS(=O)(=O)N2CCOCC2)cc1C1=CCCCC1)c1nc(c[nH]1)C#N |t:22| Show InChI InChI=1S/C23H27N5O4S/c24-15-19-16-25-22(26-19)23(29)27-21-7-6-17(14-20(21)18-4-2-1-3-5-18)8-13-33(30,31)28-9-11-32-12-10-28/h4,6-7,14,16H,1-3,5,8-13H2,(H,25,26)(H,27,29)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198863 (US9221797, 26) Show SMILES O=C(Nc1ccc(CCS(=O)(=O)N2CCOCC2)cc1C1=CCCCC1)c1nc(c[nH]1)C#N |t:22| Show InChI InChI=1S/C23H27N5O4S/c24-15-19-16-25-22(26-19)23(29)27-21-7-6-17(14-20(21)18-4-2-1-3-5-18)8-13-33(30,31)28-9-11-32-12-10-28/h4,6-7,14,16H,1-3,5,8-13H2,(H,25,26)(H,27,29)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.70	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198875 (US9221797, 48) Show SMILES OC(=O)C=Cc1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCCCC1 |w:3.2,t:23| Show InChI InChI=1S/C20H18N4O3/c21-11-15-12-22-19(23-15)20(27)24-17-8-6-13(7-9-18(25)26)10-16(17)14-4-2-1-3-5-14/h4,6-10,12H,1-3,5H2,(H,22,23)(H,24,27)(H,25,26)/b9-7-	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.90	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198881 (US9221797, 66) Show SMILES C=C(CN1CCOCC1)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCCCC1 |t:28| Show InChI InChI=1S/C24H27N5O2/c1-17(16-29-9-11-31-12-10-29)19-7-8-22(21(13-19)18-5-3-2-4-6-18)28-24(30)23-26-15-20(14-25)27-23/h5,7-8,13,15H,1-4,6,9-12,16H2,(H,26,27)(H,28,30)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.90	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198849 (US9221797, 12) Show SMILES CC(=O)OCC(COC(C)=O)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCCCC1 |t:29| Show InChI InChI=1S/C24H26N4O5/c1-15(29)32-13-19(14-33-16(2)30)18-8-9-22(21(10-18)17-6-4-3-5-7-17)28-24(31)23-26-12-20(11-25)27-23/h6,8-10,12,19H,3-5,7,13-14H2,1-2H3,(H,26,27)(H,28,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.40	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair

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