Compile Data Set for Download or QSAR

Found 468 hits of ic50 data for polymerid = 41,50000766   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50226792 (4-(3-(1-benzhydryl-5-chloro-2-(2-((3,4-dichlorophe...) Show SMILES OC(=O)c1ccc(CCCc2c(CCNS(=O)(=O)Cc3ccc(Cl)c(Cl)c3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C40H35Cl3N2O4S/c41-32-19-21-37-34(25-32)33(13-7-8-27-14-17-31(18-15-27)40(46)47)38(22-23-44-50(48,49)26-28-16-20-35(42)36(43)24-28)45(37)39(29-9-3-1-4-10-29)30-11-5-2-6-12-30/h1-6,9-12,14-21,24-25,39,44H,7-8,13,22-23,26H2,(H,46,47)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.540	n/a	n/a	n/a	n/a	n/a	n/a
Asubio Pharma Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of cPLA2alpha isolated from human U937 cell cytoplasm assessed as suppression of [14C]arachidonic acid release from L-alpha-1-palmitoyl-2-...				J Med Chem 57: 7244-62 (2014) Article DOI: 10.1021/jm500494y BindingDB Entry DOI: 10.7270/Q2F47QSP
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50185354 (3-methylhydrogen 1-[3-(4-decyloxyphenoxy)-2-oxopro...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)Cn2cc(C(=O)OC)c3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C30H37NO7/c1-3-4-5-6-7-8-9-10-17-37-24-12-14-25(15-13-24)38-21-23(32)19-31-20-27(30(35)36-2)26-18-22(29(33)34)11-16-28(26)31/h11-16,18,20H,3-10,17,19,21H2,1-2H3,(H,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
University of Münster Curated by ChEMBL					Assay Description Inhibition of cPLA2-alpha activity assessed by TPA-induced arachidonic acid release in human platelet				J Med Chem 49: 2611-20 (2006) Article DOI: 10.1021/jm051243a BindingDB Entry DOI: 10.7270/Q2668CSF
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50185348 (3-(methoxycarbonyl)-1-(3-(4-octylphenoxy)-2-oxopro...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2cc(C(=O)OC)c3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C28H33NO6/c1-3-4-5-6-7-8-9-20-10-13-23(14-11-20)35-19-22(30)17-29-18-25(28(33)34-2)24-16-21(27(31)32)12-15-26(24)29/h10-16,18H,3-9,17,19H2,1-2H3,(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
University of Münster Curated by ChEMBL					Assay Description Inhibition of cPLA2-alpha activity assessed by TPA-induced arachidonic acid release in human platelet				J Med Chem 49: 2611-20 (2006) Article DOI: 10.1021/jm051243a BindingDB Entry DOI: 10.7270/Q2668CSF
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50085993 ((E)-N-(((2S,4R)-4-((biphenyl-2-ylmethyl)(isobutyl)...) Show SMILES CC(C)CN(Cc1ccccc1-c1ccccc1)[C@@H]1C[C@@H](CNC(=O)C=Cc2ccc(C=C3SC(O)=NC3=O)cc2)N(C1)C(=O)c1ccccc1C(=O)c1ccc(F)cc1F |w:31.32,26.28,c:37| Show InChI InChI=1S/C49H44F2N4O5S/c1-31(2)28-54(29-35-12-6-7-13-39(35)34-10-4-3-5-11-34)38-26-37(27-52-45(56)23-20-32-16-18-33(19-17-32)24-44-47(58)53-49(60)61-44)55(30-38)48(59)41-15-9-8-14-40(41)46(57)42-22-21-36(50)25-43(42)51/h3-25,31,37-38H,26-30H2,1-2H3,(H,52,56)(H,53,58,60)/t37-,38+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)				J Med Chem 43: 1041-4 (2000) BindingDB Entry DOI: 10.7270/Q27P8XMZ
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50085984 (CHEMBL9161 | N-[1-[2-(2,4-Difluoro-benzoyl)-benzoy...) Show SMILES CC(C)Cc1cccc(c1O[C@@H]1C[C@@H](CNC(=O)c2ccc(C=C3SC(O)=NC3=O)cc2)N(C1)C(=O)c1ccccc1C(=O)c1ccc(F)cc1F)-c1ccccc1C(C)C |w:22.22,c:27| Show InChI InChI=1S/C49H45F2N3O6S/c1-28(2)22-32-10-9-15-39(37-12-6-5-11-36(37)29(3)4)45(32)60-35-25-34(26-52-46(56)31-18-16-30(17-19-31)23-43-47(57)53-49(59)61-43)54(27-35)48(58)40-14-8-7-13-38(40)44(55)41-21-20-33(50)24-42(41)51/h5-21,23-24,28-29,34-35H,22,25-27H2,1-4H3,(H,52,56)(H,53,57,59)/t34-,35+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)				J Med Chem 43: 1041-4 (2000) BindingDB Entry DOI: 10.7270/Q27P8XMZ
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50085986 (CHEMBL267258 | N-{4-(Biphenyl-2-ylmethyl-isobutyl-...) Show SMILES CC(C)CN(Cc1ccccc1-c1ccccc1)[C@@H]1C[C@@H](CNC(=O)C=Cc2ccc(C=C3SC(O)=NC3=O)cc2)N(C1)C(=O)c1ccccc1C(=O)c1ccc(F)cc1 |w:31.32,26.28,c:37| Show InChI InChI=1S/C49H45FN4O5S/c1-32(2)29-53(30-37-12-6-7-13-41(37)35-10-4-3-5-11-35)40-27-39(28-51-45(55)25-20-33-16-18-34(19-17-33)26-44-47(57)52-49(59)60-44)54(31-40)48(58)43-15-9-8-14-42(43)46(56)36-21-23-38(50)24-22-36/h3-26,32,39-40H,27-31H2,1-2H3,(H,51,55)(H,52,57,59)/t39-,40+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)				J Med Chem 43: 1041-4 (2000) BindingDB Entry DOI: 10.7270/Q27P8XMZ
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50185354 (3-methylhydrogen 1-[3-(4-decyloxyphenoxy)-2-oxopro...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)Cn2cc(C(=O)OC)c3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C30H37NO7/c1-3-4-5-6-7-8-9-10-17-37-24-12-14-25(15-13-24)38-21-23(32)19-31-20-27(30(35)36-2)26-18-22(29(33)34)11-16-28(26)31/h11-16,18,20H,3-10,17,19,21H2,1-2H3,(H,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
University of Münster Curated by ChEMBL					Assay Description Inhibition of human isolated cPLA2alpha by vescicle assay				J Med Chem 49: 2611-20 (2006) Article DOI: 10.1021/jm051243a BindingDB Entry DOI: 10.7270/Q2668CSF
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50185348 (3-(methoxycarbonyl)-1-(3-(4-octylphenoxy)-2-oxopro...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2cc(C(=O)OC)c3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C28H33NO6/c1-3-4-5-6-7-8-9-20-10-13-23(14-11-20)35-19-22(30)17-29-18-25(28(33)34-2)24-16-21(27(31)32)12-15-26(24)29/h10-16,18H,3-9,17,19H2,1-2H3,(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
University of Münster Curated by ChEMBL					Assay Description Inhibition of human isolated cPLA2alpha by vescicle assay				J Med Chem 49: 2611-20 (2006) Article DOI: 10.1021/jm051243a BindingDB Entry DOI: 10.7270/Q2668CSF
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50185348 (3-(methoxycarbonyl)-1-(3-(4-octylphenoxy)-2-oxopro...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2cc(C(=O)OC)c3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C28H33NO6/c1-3-4-5-6-7-8-9-20-10-13-23(14-11-20)35-19-22(30)17-29-18-25(28(33)34-2)24-16-21(27(31)32)12-15-26(24)29/h10-16,18H,3-9,17,19H2,1-2H3,(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Inhibition of cPLA2 from human platelets by RP-HPLC				Bioorg Med Chem 18: 945-52 (2010) Article DOI: 10.1016/j.bmc.2009.11.028 BindingDB Entry DOI: 10.7270/Q2N016MF
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50277800 (1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indazole-5-c...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2ncc3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C25H30N2O4/c1-2-3-4-5-6-7-8-19-9-12-23(13-10-19)31-18-22(28)17-27-24-14-11-20(25(29)30)15-21(24)16-26-27/h9-16H,2-8,17-18H2,1H3,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Inhibition of cPLA2 from human platelets by RP-HPLC				Bioorg Med Chem 18: 945-52 (2010) Article DOI: 10.1016/j.bmc.2009.11.028 BindingDB Entry DOI: 10.7270/Q2N016MF
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50185348 (3-(methoxycarbonyl)-1-(3-(4-octylphenoxy)-2-oxopro...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2cc(C(=O)OC)c3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C28H33NO6/c1-3-4-5-6-7-8-9-20-10-13-23(14-11-20)35-19-22(30)17-29-18-25(28(33)34-2)24-16-21(27(31)32)12-15-26(24)29/h10-16,18H,3-9,17,19H2,1-2H3,(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of Münster Curated by ChEMBL					Assay Description Inhibition of human platelet cPLA2-alpha assessed as arachidonic acid release by vesicle assay				Bioorg Med Chem 15: 2883-91 (2007) Article DOI: 10.1016/j.bmc.2007.02.016 BindingDB Entry DOI: 10.7270/Q24749JP
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50277800 (1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indazole-5-c...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2ncc3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C25H30N2O4/c1-2-3-4-5-6-7-8-19-9-12-23(13-10-19)31-18-22(28)17-27-24-14-11-20(25(29)30)15-21(24)16-26-27/h9-16H,2-8,17-18H2,1H3,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Inhibition of cPLA2 in human platelets assessed as arachidonic acid release				Bioorg Med Chem Lett 19: 2107-11 (2009) Article DOI: 10.1016/j.bmcl.2009.03.019 BindingDB Entry DOI: 10.7270/Q26H4JB8
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50085987 (4-(2,4-Dioxo-thiazolidin-5-ylidenemethyl)-N-[1-[2-...) Show SMILES CC(C)Cc1cccc(c1O[C@@H]1C[C@@H](CNC(=O)c2ccc(C=C3SC(O)=NC3=O)cc2)N(C1)C(=O)c1ccccc1C(=O)c1ccc(F)cc1)-c1ccccc1C(C)C |w:22.22,c:27| Show InChI InChI=1S/C49H46FN3O6S/c1-29(2)24-34-10-9-15-41(39-12-6-5-11-38(39)30(3)4)45(34)59-37-26-36(27-51-46(55)33-18-16-31(17-19-33)25-43-47(56)52-49(58)60-43)53(28-37)48(57)42-14-8-7-13-40(42)44(54)32-20-22-35(50)23-21-32/h5-23,25,29-30,36-37H,24,26-28H2,1-4H3,(H,51,55)(H,52,56,58)/t36-,37+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)				J Med Chem 43: 1041-4 (2000) BindingDB Entry DOI: 10.7270/Q27P8XMZ
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50292791 (4-{3-[2-{2-[({2-[(4-Acetylpiperazin-1-yl)methyl]be...) Show SMILES CC(=O)N1CCN(Cc2ccccc2CS(=O)(=O)NCCc2c(CCCc3ccc(cc3)C(O)=O)c3cc(Cl)ccc3n2C(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C47H49ClN4O5S/c1-34(53)51-29-27-50(28-30-51)32-39-16-8-9-17-40(39)33-58(56,57)49-26-25-45-42(18-10-11-35-19-21-38(22-20-35)47(54)55)43-31-41(48)23-24-44(43)52(45)46(36-12-4-2-5-13-36)37-14-6-3-7-15-37/h2-9,12-17,19-24,31,46,49H,10-11,18,25-30,32-33H2,1H3,(H,54,55)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human cytosolic PLA2alpha by GLU micelle assay				J Med Chem 52: 1156-71 (2009) Article DOI: 10.1021/jm8009876 BindingDB Entry DOI: 10.7270/Q20C4VSK
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50085994 (CHEMBL8970 | N-{4-(Biphenyl-2-ylmethyl-isobutyl-am...) Show SMILES CC(C)CN(Cc1ccccc1-c1ccccc1)[C@@H]1C[C@@H](CNC(=O)c2ccc(C=C3SC(O)=NC3=O)cc2)N(C1)C(=O)c1ccccc1C(=O)c1ccc(F)cc1F |w:29.30,c:35| Show InChI InChI=1S/C47H42F2N4O5S/c1-29(2)26-52(27-33-12-6-7-13-37(33)31-10-4-3-5-11-31)36-24-35(25-50-44(55)32-18-16-30(17-19-32)22-42-45(56)51-47(58)59-42)53(28-36)46(57)39-15-9-8-14-38(39)43(54)40-21-20-34(48)23-41(40)49/h3-23,29,35-36H,24-28H2,1-2H3,(H,50,55)(H,51,56,58)/t35-,36+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)				J Med Chem 43: 1041-4 (2000) BindingDB Entry DOI: 10.7270/Q27P8XMZ
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50185351 (3-acetyl-1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-ind...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2cc(C(C)=O)c3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C28H33NO5/c1-3-4-5-6-7-8-9-21-10-13-24(14-11-21)34-19-23(31)17-29-18-26(20(2)30)25-16-22(28(32)33)12-15-27(25)29/h10-16,18H,3-9,17,19H2,1-2H3,(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Münster Curated by ChEMBL					Assay Description Inhibition of cPLA2-alpha activity assessed by TPA-induced arachidonic acid release in human platelet				J Med Chem 49: 2611-20 (2006) Article DOI: 10.1021/jm051243a BindingDB Entry DOI: 10.7270/Q2668CSF
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50056707 (CHEMBL3326971) Show SMILES CCCOc1ccc(cc1)-n1cc(CCc2ccccc2)c2cc(CCC(O)=O)ccc12 Show InChI InChI=1S/C28H29NO3/c1-2-18-32-25-14-12-24(13-15-25)29-20-23(11-8-21-6-4-3-5-7-21)26-19-22(9-16-27(26)29)10-17-28(30)31/h3-7,9,12-16,19-20H,2,8,10-11,17-18H2,1H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Asubio Pharma Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of cPLA2alpha isolated from human U937 cell cytoplasm assessed as suppression of [14C]arachidonic acid release from L-alpha-1-palmitoyl-2-...				J Med Chem 57: 7244-62 (2014) Article DOI: 10.1021/jm500494y BindingDB Entry DOI: 10.7270/Q2F47QSP
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50056741 (CHEMBL3327088) Show SMILES CC(C)Oc1ccc(cc1)-n1cc(CCc2ccccc2)c2cc(CCC(O)=O)ccc12 Show InChI InChI=1S/C28H29NO3/c1-20(2)32-25-14-12-24(13-15-25)29-19-23(11-8-21-6-4-3-5-7-21)26-18-22(9-16-27(26)29)10-17-28(30)31/h3-7,9,12-16,18-20H,8,10-11,17H2,1-2H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Asubio Pharma Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of cPLA2alpha isolated from human U937 cell cytoplasm assessed as suppression of [14C]arachidonic acid release from L-alpha-1-palmitoyl-2-...				J Med Chem 57: 7244-62 (2014) Article DOI: 10.1021/jm500494y BindingDB Entry DOI: 10.7270/Q2F47QSP
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50185350 (1-(3-(4-(decyloxy)phenoxy)-2-oxopropyl)-1H-indole-...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)Cn2ccc3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C28H35NO5/c1-2-3-4-5-6-7-8-9-18-33-25-11-13-26(14-12-25)34-21-24(30)20-29-17-16-22-19-23(28(31)32)10-15-27(22)29/h10-17,19H,2-9,18,20-21H2,1H3,(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
University of Münster Curated by ChEMBL					Assay Description Inhibition of cPLA2-alpha activity assessed by TPA-induced arachidonic acid release in human platelet				J Med Chem 49: 2611-20 (2006) Article DOI: 10.1021/jm051243a BindingDB Entry DOI: 10.7270/Q2668CSF
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50185349 (3-formyl-1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-ind...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2cc(C=O)c3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C27H31NO5/c1-2-3-4-5-6-7-8-20-9-12-24(13-10-20)33-19-23(30)17-28-16-22(18-29)25-15-21(27(31)32)11-14-26(25)28/h9-16,18H,2-8,17,19H2,1H3,(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
University of Münster Curated by ChEMBL					Assay Description Inhibition of cPLA2-alpha activity assessed by TPA-induced arachidonic acid release in human platelet				J Med Chem 49: 2611-20 (2006) Article DOI: 10.1021/jm051243a BindingDB Entry DOI: 10.7270/Q2668CSF
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50292792 (4-(3-{5-Chloro-1-(diphenylmethyl)-2-[2-({[2-(morph...) Show SMILES OC(=O)c1ccc(CCCc2c(CCNS(=O)(=O)Cc3ccccc3CN3CCOCC3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C45H46ClN3O5S/c46-39-22-23-42-41(30-39)40(17-9-10-33-18-20-36(21-19-33)45(50)51)43(49(42)44(34-11-3-1-4-12-34)35-13-5-2-6-14-35)24-25-47-55(52,53)32-38-16-8-7-15-37(38)31-48-26-28-54-29-27-48/h1-8,11-16,18-23,30,44,47H,9-10,17,24-29,31-32H2,(H,50,51)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human cytosolic PLA2alpha by GLU micelle assay				J Med Chem 52: 1156-71 (2009) Article DOI: 10.1021/jm8009876 BindingDB Entry DOI: 10.7270/Q20C4VSK
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50233835 (CHEMBL4097068) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2cc(C(=O)C(C)C)c3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C30H37NO5/c1-4-5-6-7-8-9-10-22-11-14-25(15-12-22)36-20-24(32)18-31-19-27(29(33)21(2)3)26-17-23(30(34)35)13-16-28(26)31/h11-17,19,21H,4-10,18,20H2,1-3H3,(H,34,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Inhibition of human platelet cytosolic phospholipase alpha-2 using 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine/1,2-dioleoyl-sn-glycerol as ...				Eur J Med Chem 125: 1107-1114 (2017) Article DOI: 10.1016/j.ejmech.2016.10.039 BindingDB Entry DOI: 10.7270/Q2DB8448
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50233832 (CHEMBL1800991) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2cc(C(=O)CCC)c3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C30H37NO5/c1-3-5-6-7-8-9-11-22-12-15-25(16-13-22)36-21-24(32)19-31-20-27(29(33)10-4-2)26-18-23(30(34)35)14-17-28(26)31/h12-18,20H,3-11,19,21H2,1-2H3,(H,34,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Inhibition of human platelet cytosolic phospholipase alpha-2 using 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine/1,2-dioleoyl-sn-glycerol as ...				Eur J Med Chem 125: 1107-1114 (2017) Article DOI: 10.1016/j.ejmech.2016.10.039 BindingDB Entry DOI: 10.7270/Q2DB8448
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50226793 (4-(3-(1-benzhydryl-5-chloro-2-(2-((2,6-dimethylphe...) Show SMILES Cc1cccc(C)c1CS(=O)(=O)NCCc1c(CCCc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C42H41ClN2O4S/c1-29-11-9-12-30(2)38(29)28-50(48,49)44-26-25-40-36(18-10-13-31-19-21-34(22-20-31)42(46)47)37-27-35(43)23-24-39(37)45(40)41(32-14-5-3-6-15-32)33-16-7-4-8-17-33/h3-9,11-12,14-17,19-24,27,41,44H,10,13,18,25-26,28H2,1-2H3,(H,46,47)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human cytosolic PLA2alpha by GLU micelle assay				J Med Chem 52: 1156-71 (2009) Article DOI: 10.1021/jm8009876 BindingDB Entry DOI: 10.7270/Q20C4VSK
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50185345 (3-cyano-1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indo...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2cc(C#N)c3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C27H30N2O4/c1-2-3-4-5-6-7-8-20-9-12-24(13-10-20)33-19-23(30)18-29-17-22(16-28)25-15-21(27(31)32)11-14-26(25)29/h9-15,17H,2-8,18-19H2,1H3,(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of Münster Curated by ChEMBL					Assay Description Inhibition of cPLA2-alpha activity assessed by TPA-induced arachidonic acid release in human platelet				J Med Chem 49: 2611-20 (2006) Article DOI: 10.1021/jm051243a BindingDB Entry DOI: 10.7270/Q2668CSF
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50110846 (4-(3-(4-(decyloxy)phenoxy)-2-oxopropoxy)benzoic ac...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)COc2ccc(cc2)C(O)=O)cc1 Show InChI InChI=1S/C26H34O6/c1-2-3-4-5-6-7-8-9-18-30-23-14-16-25(17-15-23)32-20-22(27)19-31-24-12-10-21(11-13-24)26(28)29/h10-17H,2-9,18-20H2,1H3,(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Inhibition of human platelet cytosolic phospholipase alpha-2 using 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine/1,2-dioleoyl-sn-glycerol as ...				Eur J Med Chem 125: 1107-1114 (2017) Article DOI: 10.1016/j.ejmech.2016.10.039 BindingDB Entry DOI: 10.7270/Q2DB8448
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50110846 (4-(3-(4-(decyloxy)phenoxy)-2-oxopropoxy)benzoic ac...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)COc2ccc(cc2)C(O)=O)cc1 Show InChI InChI=1S/C26H34O6/c1-2-3-4-5-6-7-8-9-18-30-23-14-16-25(17-15-23)32-20-22(27)19-31-24-12-10-21(11-13-24)26(28)29/h10-17H,2-9,18-20H2,1H3,(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Inhibition of cPLA2 in human platelets assessed as arachidonic acid release				Bioorg Med Chem Lett 19: 2107-11 (2009) Article DOI: 10.1016/j.bmcl.2009.03.019 BindingDB Entry DOI: 10.7270/Q26H4JB8
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50110846 (4-(3-(4-(decyloxy)phenoxy)-2-oxopropoxy)benzoic ac...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)COc2ccc(cc2)C(O)=O)cc1 Show InChI InChI=1S/C26H34O6/c1-2-3-4-5-6-7-8-9-18-30-23-14-16-25(17-15-23)32-20-22(27)19-31-24-12-10-21(11-13-24)26(28)29/h10-17H,2-9,18-20H2,1H3,(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of Münster Curated by ChEMBL					Assay Description Inhibition of human isolated cPLA2alpha by vescicle assay				J Med Chem 49: 2611-20 (2006) Article DOI: 10.1021/jm051243a BindingDB Entry DOI: 10.7270/Q2668CSF
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50110846 (4-(3-(4-(decyloxy)phenoxy)-2-oxopropoxy)benzoic ac...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)COc2ccc(cc2)C(O)=O)cc1 Show InChI InChI=1S/C26H34O6/c1-2-3-4-5-6-7-8-9-18-30-23-14-16-25(17-15-23)32-20-22(27)19-31-24-12-10-21(11-13-24)26(28)29/h10-17H,2-9,18-20H2,1H3,(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Inhibition of cPLA2 from human platelets by RP-HPLC				Bioorg Med Chem 18: 945-52 (2010) Article DOI: 10.1016/j.bmc.2009.11.028 BindingDB Entry DOI: 10.7270/Q2N016MF
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50056712 (CHEMBL3326966) Show SMILES OC(=O)CCc1ccc2n(cc(CCc3ccccc3)c2c1)-c1ccc(O)cc1 Show InChI InChI=1S/C25H23NO3/c27-22-12-10-21(11-13-22)26-17-20(9-6-18-4-2-1-3-5-18)23-16-19(7-14-24(23)26)8-15-25(28)29/h1-5,7,10-14,16-17,27H,6,8-9,15H2,(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Asubio Pharma Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of cPLA2alpha isolated from human U937 cell cytoplasm assessed as suppression of [14C]arachidonic acid release from L-alpha-1-palmitoyl-2-...				J Med Chem 57: 7244-62 (2014) Article DOI: 10.1021/jm500494y BindingDB Entry DOI: 10.7270/Q2F47QSP
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50110846 (4-(3-(4-(decyloxy)phenoxy)-2-oxopropoxy)benzoic ac...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)COc2ccc(cc2)C(O)=O)cc1 Show InChI InChI=1S/C26H34O6/c1-2-3-4-5-6-7-8-9-18-30-23-14-16-25(17-15-23)32-20-22(27)19-31-24-12-10-21(11-13-24)26(28)29/h10-17H,2-9,18-20H2,1H3,(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of Münster Curated by ChEMBL					Assay Description Inhibition of human platelet cPLA2-alpha assessed as arachidonic acid release by vesicle assay				Bioorg Med Chem 15: 2883-91 (2007) Article DOI: 10.1016/j.bmc.2007.02.016 BindingDB Entry DOI: 10.7270/Q24749JP
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50233833 (CHEMBL1085637) Show SMILES CC(C)C(=O)c1cn(CC(=O)COc2ccc(Oc3ccccc3)cc2)c2ccc(cc12)C(O)=O Show InChI InChI=1S/C28H25NO6/c1-18(2)27(31)25-16-29(26-13-8-19(28(32)33)14-24(25)26)15-20(30)17-34-21-9-11-23(12-10-21)35-22-6-4-3-5-7-22/h3-14,16,18H,15,17H2,1-2H3,(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Inhibition of human platelet cytosolic phospholipase alpha-2 using 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine/1,2-dioleoyl-sn-glycerol as ...				Eur J Med Chem 125: 1107-1114 (2017) Article DOI: 10.1016/j.ejmech.2016.10.039 BindingDB Entry DOI: 10.7270/Q2DB8448
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50185351 (3-acetyl-1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-ind...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2cc(C(C)=O)c3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C28H33NO5/c1-3-4-5-6-7-8-9-21-10-13-24(14-11-21)34-19-23(31)17-29-18-26(20(2)30)25-16-22(28(32)33)12-15-27(25)29/h10-16,18H,3-9,17,19H2,1-2H3,(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Inhibition of cPLA2 from human platelets by RP-HPLC				Bioorg Med Chem 18: 945-52 (2010) Article DOI: 10.1016/j.bmc.2009.11.028 BindingDB Entry DOI: 10.7270/Q2N016MF
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50292790 (4-(3-{5-Chloro-1-(diphenylmethyl)-2-[2-({[2-(piper...) Show SMILES OC(=O)c1ccc(CCCc2c(CCNS(=O)(=O)Cc3ccccc3CN3CCNCC3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C45H47ClN4O4S/c46-39-22-23-42-41(30-39)40(17-9-10-33-18-20-36(21-19-33)45(51)52)43(50(42)44(34-11-3-1-4-12-34)35-13-5-2-6-14-35)24-25-48-55(53,54)32-38-16-8-7-15-37(38)31-49-28-26-47-27-29-49/h1-8,11-16,18-23,30,44,47-48H,9-10,17,24-29,31-32H2,(H,51,52)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human cytosolic PLA2alpha by GLU micelle assay				J Med Chem 52: 1156-71 (2009) Article DOI: 10.1021/jm8009876 BindingDB Entry DOI: 10.7270/Q20C4VSK
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50056740 (CHEMBL3327089) Show SMILES NC(CO)(CO)CO.OCCOc1ccc(cc1)-n1cc(CCc2ccccc2)c2cc(CCC(O)=O)ccc12 Show InChI InChI=1S/C27H27NO4/c29-16-17-32-24-12-10-23(11-13-24)28-19-22(9-6-20-4-2-1-3-5-20)25-18-21(7-14-26(25)28)8-15-27(30)31/h1-5,7,10-14,18-19,29H,6,8-9,15-17H2,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Asubio Pharma Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of cPLA2alpha isolated from human U937 cell cytoplasm assessed as suppression of [14C]arachidonic acid release from L-alpha-1-palmitoyl-2-...				J Med Chem 57: 7244-62 (2014) Article DOI: 10.1021/jm500494y BindingDB Entry DOI: 10.7270/Q2F47QSP
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50185345 (3-cyano-1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indo...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2cc(C#N)c3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C27H30N2O4/c1-2-3-4-5-6-7-8-20-9-12-24(13-10-20)33-19-23(30)18-29-17-22(16-28)25-15-21(27(31)32)11-14-26(25)29/h9-15,17H,2-8,18-19H2,1H3,(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
University of Münster Curated by ChEMBL					Assay Description Inhibition of human isolated cPLA2alpha by vescicle assay				J Med Chem 49: 2611-20 (2006) Article DOI: 10.1021/jm051243a BindingDB Entry DOI: 10.7270/Q2668CSF
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50233834 (CHEMBL4079052) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2cc(C(=O)CCCOC)c3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C31H39NO6/c1-3-4-5-6-7-8-10-23-12-15-26(16-13-23)38-22-25(33)20-32-21-28(30(34)11-9-18-37-2)27-19-24(31(35)36)14-17-29(27)32/h12-17,19,21H,3-11,18,20,22H2,1-2H3,(H,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Inhibition of human platelet cytosolic phospholipase alpha-2 using 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine/1,2-dioleoyl-sn-glycerol as ...				Eur J Med Chem 125: 1107-1114 (2017) Article DOI: 10.1016/j.ejmech.2016.10.039 BindingDB Entry DOI: 10.7270/Q2DB8448
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50185345 (3-cyano-1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indo...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2cc(C#N)c3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C27H30N2O4/c1-2-3-4-5-6-7-8-20-9-12-24(13-10-20)33-19-23(30)18-29-17-22(16-28)25-15-21(27(31)32)11-14-26(25)29/h9-15,17H,2-8,18-19H2,1H3,(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Inhibition of cPLA2 from human platelets by RP-HPLC				Bioorg Med Chem 18: 945-52 (2010) Article DOI: 10.1016/j.bmc.2009.11.028 BindingDB Entry DOI: 10.7270/Q2N016MF
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50056708 (CHEMBL3326970) Show SMILES NC(CO)(CO)CO.CCOc1ccc(cc1)-n1cc(CCc2ccccc2)c2cc(CCC(O)=O)ccc12 Show InChI InChI=1S/C27H27NO3/c1-2-31-24-14-12-23(13-15-24)28-19-22(11-8-20-6-4-3-5-7-20)25-18-21(9-16-26(25)28)10-17-27(29)30/h3-7,9,12-16,18-19H,2,8,10-11,17H2,1H3,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Asubio Pharma Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of cPLA2alpha isolated from human U937 cell cytoplasm assessed as suppression of [14C]arachidonic acid release from L-alpha-1-palmitoyl-2-...				J Med Chem 57: 7244-62 (2014) Article DOI: 10.1021/jm500494y BindingDB Entry DOI: 10.7270/Q2F47QSP
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50185351 (3-acetyl-1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-ind...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2cc(C(C)=O)c3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C28H33NO5/c1-3-4-5-6-7-8-9-21-10-13-24(14-11-21)34-19-23(31)17-29-18-26(20(2)30)25-16-22(28(32)33)12-15-27(25)29/h10-16,18H,3-9,17,19H2,1-2H3,(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
University of Münster Curated by ChEMBL					Assay Description Inhibition of human isolated cPLA2alpha by vescicle assay				J Med Chem 49: 2611-20 (2006) Article DOI: 10.1021/jm051243a BindingDB Entry DOI: 10.7270/Q2668CSF
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50185349 (3-formyl-1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-ind...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2cc(C=O)c3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C27H31NO5/c1-2-3-4-5-6-7-8-20-9-12-24(13-10-20)33-19-23(30)17-28-16-22(18-29)25-15-21(27(31)32)11-14-26(25)28/h9-16,18H,2-8,17,19H2,1H3,(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
University of Münster Curated by ChEMBL					Assay Description Inhibition of human isolated cPLA2alpha by vescicle assay				J Med Chem 49: 2611-20 (2006) Article DOI: 10.1021/jm051243a BindingDB Entry DOI: 10.7270/Q2668CSF
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50277799 (1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-benzo[d][1,2...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2nnc3ccc(cc23)C(O)=O)cc1 Show InChI InChI=1S/C24H29N3O4/c1-2-3-4-5-6-7-8-18-9-12-21(13-10-18)31-17-20(28)16-27-23-15-19(24(29)30)11-14-22(23)25-26-27/h9-15H,2-8,16-17H2,1H3,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Inhibition of cPLA2 from human platelets by RP-HPLC				Bioorg Med Chem 18: 945-52 (2010) Article DOI: 10.1016/j.bmc.2009.11.028 BindingDB Entry DOI: 10.7270/Q2N016MF
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50185349 (3-formyl-1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-ind...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2cc(C=O)c3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C27H31NO5/c1-2-3-4-5-6-7-8-20-9-12-24(13-10-20)33-19-23(30)17-28-16-22(18-29)25-15-21(27(31)32)11-14-26(25)28/h9-16,18H,2-8,17,19H2,1H3,(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Inhibition of cPLA2 from human platelets by RP-HPLC				Bioorg Med Chem 18: 945-52 (2010) Article DOI: 10.1016/j.bmc.2009.11.028 BindingDB Entry DOI: 10.7270/Q2N016MF
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50277799 (1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-benzo[d][1,2...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2nnc3ccc(cc23)C(O)=O)cc1 Show InChI InChI=1S/C24H29N3O4/c1-2-3-4-5-6-7-8-18-9-12-21(13-10-18)31-17-20(28)16-27-23-15-19(24(29)30)11-14-22(23)25-26-27/h9-15H,2-8,16-17H2,1H3,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Inhibition of cPLA2 in human platelets assessed as arachidonic acid release				Bioorg Med Chem Lett 19: 2107-11 (2009) Article DOI: 10.1016/j.bmcl.2009.03.019 BindingDB Entry DOI: 10.7270/Q26H4JB8
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50185356 (1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indole-5-car...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2ccc3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C26H31NO4/c1-2-3-4-5-6-7-8-20-9-12-24(13-10-20)31-19-23(28)18-27-16-15-21-17-22(26(29)30)11-14-25(21)27/h9-17H,2-8,18-19H2,1H3,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Inhibition of cPLA2-alpha in TPA-stimulated intact human platelets assessed as liberation of arachidonic acid after 60 mins				Bioorg Med Chem 16: 3489-500 (2008) Article DOI: 10.1016/j.bmc.2008.02.019 BindingDB Entry DOI: 10.7270/Q2W66MN0
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50185356 (1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indole-5-car...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2ccc3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C26H31NO4/c1-2-3-4-5-6-7-8-20-9-12-24(13-10-20)31-19-23(28)18-27-16-15-21-17-22(26(29)30)11-14-25(21)27/h9-17H,2-8,18-19H2,1H3,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of Münster Curated by ChEMBL					Assay Description Inhibition of cPLA2-alpha activity assessed by TPA-induced arachidonic acid release in human platelet				J Med Chem 49: 2611-20 (2006) Article DOI: 10.1021/jm051243a BindingDB Entry DOI: 10.7270/Q2668CSF
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50185350 (1-(3-(4-(decyloxy)phenoxy)-2-oxopropyl)-1H-indole-...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)Cn2ccc3cc(ccc23)C(O)=O)cc1 Show InChI InChI=1S/C28H35NO5/c1-2-3-4-5-6-7-8-9-18-33-25-11-13-26(14-12-25)34-21-24(30)20-29-17-16-22-19-23(28(31)32)10-15-27(22)29/h10-17,19H,2-9,18,20-21H2,1H3,(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
University of Münster Curated by ChEMBL					Assay Description Inhibition of human isolated cPLA2alpha by vescicle assay				J Med Chem 49: 2611-20 (2006) Article DOI: 10.1021/jm051243a BindingDB Entry DOI: 10.7270/Q2668CSF
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50292789 (4-[3-(5-Chloro-1-(diphenylmethyl)-2-{2-[({2-[(4-me...) Show SMILES CN1CCN(Cc2ccccc2CS(=O)(=O)NCCc2c(CCCc3ccc(cc3)C(O)=O)c3cc(Cl)ccc3n2C(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C46H49ClN4O4S/c1-49-27-29-50(30-28-49)32-38-16-8-9-17-39(38)33-56(54,55)48-26-25-44-41(18-10-11-34-19-21-37(22-20-34)46(52)53)42-31-40(47)23-24-43(42)51(44)45(35-12-4-2-5-13-35)36-14-6-3-7-15-36/h2-9,12-17,19-24,31,45,48H,10-11,18,25-30,32-33H2,1H3,(H,52,53)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human cytosolic PLA2alpha by GLU micelle assay				J Med Chem 52: 1156-71 (2009) Article DOI: 10.1021/jm8009876 BindingDB Entry DOI: 10.7270/Q20C4VSK
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50056737 (CHEMBL3327092) Show SMILES NC(CO)(CO)CO.OC(=O)CCc1ccc2n(cc(CCc3ccccc3)c2c1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C31H27NO3/c33-31(34)20-13-24-12-19-30-29(21-24)25(14-11-23-7-3-1-4-8-23)22-32(30)26-15-17-28(18-16-26)35-27-9-5-2-6-10-27/h1-10,12,15-19,21-22H,11,13-14,20H2,(H,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Asubio Pharma Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of cPLA2alpha isolated from human U937 cell cytoplasm assessed as suppression of [14C]arachidonic acid release from L-alpha-1-palmitoyl-2-...				J Med Chem 57: 7244-62 (2014) Article DOI: 10.1021/jm500494y BindingDB Entry DOI: 10.7270/Q2F47QSP
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Homo sapiens (Human))	BDBM50085980 (CHEMBL428996 | N-{4-(Biphenyl-2-ylmethyl-isobutyl-...) Show SMILES CC(C)CN(Cc1ccccc1-c1ccccc1)[C@@H]1C[C@@H](CNC(=O)c2ccc(C=C3SC(O)=NC3=O)cc2)N(C1)C(=O)c1ccccc1C(=O)c1ccc(F)cc1 |w:29.30,c:35| Show InChI InChI=1S/C47H43FN4O5S/c1-30(2)27-51(28-35-12-6-7-13-39(35)32-10-4-3-5-11-32)38-25-37(26-49-44(54)34-18-16-31(17-19-34)24-42-45(55)50-47(57)58-42)52(29-38)46(56)41-15-9-8-14-40(41)43(53)33-20-22-36(48)23-21-33/h3-24,30,37-38H,25-29H2,1-2H3,(H,49,54)(H,50,55,57)/t37-,38+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of Human cPLA2 alpha using Enzyme assay(PC/DOG assay)				J Med Chem 43: 1041-4 (2000) BindingDB Entry DOI: 10.7270/Q27P8XMZ
					More data for this Ligand-Target Pair

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