Compile Data Set for Download or QSAR

Found 20 hits of ic50 data for polymerid = 49000332   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (MOUSE)	BDBM50023629 (CHEMBL3341861) Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)cc1 Show InChI InChI=1S/C22H21ClN4O/c23-17-9-11-18(12-10-17)24-22(28)25-19-6-3-5-16(15-19)20-7-4-8-21(26-20)27-13-1-2-14-27/h3-12,15H,1-2,13-14H2,(H2,24,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute , Research Triangle Park, North Carolina 27709, United States. Curated by ChEMBL					Assay Description Allosteric modulation of CB1 receptor in CD-1 mouse cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding after 60 m...				J Med Chem 60: 7410-7424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00707 BindingDB Entry DOI: 10.7270/Q2XK8J0H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (MOUSE)	BDBM50258768 (CHEMBL4078901) Show SMILES Fc1ccc(cc1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1 Show InChI InChI=1S/C19H14ClFN2O/c20-15-6-10-17(11-7-15)22-19(24)23-18-3-1-2-14(12-18)13-4-8-16(21)9-5-13/h1-12H,(H2,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	151	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute , Research Triangle Park, North Carolina 27709, United States. Curated by ChEMBL					Assay Description Allosteric modulation of CB1 receptor in CD-1 mouse cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding after 60 m...				J Med Chem 60: 7410-7424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00707 BindingDB Entry DOI: 10.7270/Q2XK8J0H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (MOUSE)	BDBM50258771 (CHEMBL4062376) Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2ccc3occc3c2)cc1 Show InChI InChI=1S/C21H15ClN2O2/c22-17-5-7-18(8-6-17)23-21(25)24-19-3-1-2-14(13-19)15-4-9-20-16(12-15)10-11-26-20/h1-13H,(H2,23,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	265	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute , Research Triangle Park, North Carolina 27709, United States. Curated by ChEMBL					Assay Description Allosteric modulation of CB1 receptor in CD-1 mouse cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding after 60 m...				J Med Chem 60: 7410-7424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00707 BindingDB Entry DOI: 10.7270/Q2XK8J0H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (MOUSE)	BDBM50258826 (CHEMBL4067016) Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2cc(Cl)cc(Cl)c2)cc1 Show InChI InChI=1S/C19H13Cl3N2O/c20-14-4-6-17(7-5-14)23-19(25)24-18-3-1-2-12(10-18)13-8-15(21)11-16(22)9-13/h1-11H,(H2,23,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	299	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute , Research Triangle Park, North Carolina 27709, United States. Curated by ChEMBL					Assay Description Allosteric modulation of CB1 receptor in CD-1 mouse cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding after 60 m...				J Med Chem 60: 7410-7424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00707 BindingDB Entry DOI: 10.7270/Q2XK8J0H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (MOUSE)	BDBM50258769 (CHEMBL4096928) Show SMILES Fc1ccc(c(F)c1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1 Show InChI InChI=1S/C19H13ClF2N2O/c20-13-4-7-15(8-5-13)23-19(25)24-16-3-1-2-12(10-16)17-9-6-14(21)11-18(17)22/h1-11H,(H2,23,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	353	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute , Research Triangle Park, North Carolina 27709, United States. Curated by ChEMBL					Assay Description Allosteric modulation of CB1 receptor in CD-1 mouse cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding after 60 m...				J Med Chem 60: 7410-7424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00707 BindingDB Entry DOI: 10.7270/Q2XK8J0H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (MOUSE)	BDBM50258727 (CHEMBL4081259) Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2ccncc2)cc1 Show InChI InChI=1S/C18H14ClN3O/c19-15-4-6-16(7-5-15)21-18(23)22-17-3-1-2-14(12-17)13-8-10-20-11-9-13/h1-12H,(H2,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	405	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute , Research Triangle Park, North Carolina 27709, United States. Curated by ChEMBL					Assay Description Allosteric modulation of CB1 receptor in CD-1 mouse cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding after 60 m...				J Med Chem 60: 7410-7424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00707 BindingDB Entry DOI: 10.7270/Q2XK8J0H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (MOUSE)	BDBM50258738 (CHEMBL4070648) Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2ccccc2)cc1 Show InChI InChI=1S/C19H15ClN2O/c20-16-9-11-17(12-10-16)21-19(23)22-18-8-4-7-15(13-18)14-5-2-1-3-6-14/h1-13H,(H2,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	439	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute , Research Triangle Park, North Carolina 27709, United States. Curated by ChEMBL					Assay Description Allosteric modulation of CB1 receptor in CD-1 mouse cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding after 60 m...				J Med Chem 60: 7410-7424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00707 BindingDB Entry DOI: 10.7270/Q2XK8J0H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (MOUSE)	BDBM50258766 (CHEMBL4077975) Show SMILES [O-][N+](=O)c1cccc(c1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1 Show InChI InChI=1S/C19H14ClN3O3/c20-15-7-9-16(10-8-15)21-19(24)22-17-5-1-3-13(11-17)14-4-2-6-18(12-14)23(25)26/h1-12H,(H2,21,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	452	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute , Research Triangle Park, North Carolina 27709, United States. Curated by ChEMBL					Assay Description Allosteric modulation of CB1 receptor in CD-1 mouse cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding after 60 m...				J Med Chem 60: 7410-7424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00707 BindingDB Entry DOI: 10.7270/Q2XK8J0H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (MOUSE)	BDBM50258740 (CHEMBL4085844) Show SMILES Cc1cccc(c1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1 Show InChI InChI=1S/C20H17ClN2O/c1-14-4-2-5-15(12-14)16-6-3-7-19(13-16)23-20(24)22-18-10-8-17(21)9-11-18/h2-13H,1H3,(H2,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	459	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute , Research Triangle Park, North Carolina 27709, United States. Curated by ChEMBL					Assay Description Allosteric modulation of CB1 receptor in CD-1 mouse cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding after 60 m...				J Med Chem 60: 7410-7424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00707 BindingDB Entry DOI: 10.7270/Q2XK8J0H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (MOUSE)	BDBM50258767 (CHEMBL4086756) Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2ccc(Cl)c(Cl)c2)cc1 Show InChI InChI=1S/C19H13Cl3N2O/c20-14-5-7-15(8-6-14)23-19(25)24-16-3-1-2-12(10-16)13-4-9-17(21)18(22)11-13/h1-11H,(H2,23,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	464	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute , Research Triangle Park, North Carolina 27709, United States. Curated by ChEMBL					Assay Description Allosteric modulation of CB1 receptor in CD-1 mouse cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding after 60 m...				J Med Chem 60: 7410-7424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00707 BindingDB Entry DOI: 10.7270/Q2XK8J0H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (MOUSE)	BDBM50258868 (CHEMBL4073727) Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2cccc(c2)-c2ccccc2)cc1 Show InChI InChI=1S/C25H19ClN2O/c26-22-12-14-23(15-13-22)27-25(29)28-24-11-5-10-21(17-24)20-9-4-8-19(16-20)18-6-2-1-3-7-18/h1-17H,(H2,27,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	559	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute , Research Triangle Park, North Carolina 27709, United States. Curated by ChEMBL					Assay Description Allosteric modulation of CB1 receptor in CD-1 mouse cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding after 60 m...				J Med Chem 60: 7410-7424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00707 BindingDB Entry DOI: 10.7270/Q2XK8J0H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (MOUSE)	BDBM50258739 (CHEMBL4064299) Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C20H15ClN2O3/c21-15-5-7-16(8-6-15)22-20(24)23-17-3-1-2-13(10-17)14-4-9-18-19(11-14)26-12-25-18/h1-11H,12H2,(H2,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	619	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute , Research Triangle Park, North Carolina 27709, United States. Curated by ChEMBL					Assay Description Allosteric modulation of CB1 receptor in CD-1 mouse cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding after 60 m...				J Med Chem 60: 7410-7424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00707 BindingDB Entry DOI: 10.7270/Q2XK8J0H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (MOUSE)	BDBM50258781 (CHEMBL4099590) Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2cnc3ccccc3c2)cc1 Show InChI InChI=1S/C22H16ClN3O/c23-18-8-10-19(11-9-18)25-22(27)26-20-6-3-5-15(13-20)17-12-16-4-1-2-7-21(16)24-14-17/h1-14H,(H2,25,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	651	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute , Research Triangle Park, North Carolina 27709, United States. Curated by ChEMBL					Assay Description Allosteric modulation of CB1 receptor in CD-1 mouse cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding after 60 m...				J Med Chem 60: 7410-7424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00707 BindingDB Entry DOI: 10.7270/Q2XK8J0H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (MOUSE)	BDBM50258866 (CHEMBL4097779) Show SMILES COc1cccc(c1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1 Show InChI InChI=1S/C20H17ClN2O2/c1-25-19-7-3-5-15(13-19)14-4-2-6-18(12-14)23-20(24)22-17-10-8-16(21)9-11-17/h2-13H,1H3,(H2,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	827	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute , Research Triangle Park, North Carolina 27709, United States. Curated by ChEMBL					Assay Description Allosteric modulation of CB1 receptor in CD-1 mouse cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding after 60 m...				J Med Chem 60: 7410-7424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00707 BindingDB Entry DOI: 10.7270/Q2XK8J0H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (MOUSE)	BDBM50258726 (CHEMBL4078811) Show SMILES COc1cc(ccn1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1 Show InChI InChI=1S/C19H16ClN3O2/c1-25-18-12-14(9-10-21-18)13-3-2-4-17(11-13)23-19(24)22-16-7-5-15(20)6-8-16/h2-12H,1H3,(H2,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute , Research Triangle Park, North Carolina 27709, United States. Curated by ChEMBL					Assay Description Allosteric modulation of CB1 receptor in CD-1 mouse cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding after 60 m...				J Med Chem 60: 7410-7424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00707 BindingDB Entry DOI: 10.7270/Q2XK8J0H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (MOUSE)	BDBM50258772 (CHEMBL4091847) Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2ccc3ccccc3c2)cc1 Show InChI InChI=1S/C23H17ClN2O/c24-20-10-12-21(13-11-20)25-23(27)26-22-7-3-6-18(15-22)19-9-8-16-4-1-2-5-17(16)14-19/h1-15H,(H2,25,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute , Research Triangle Park, North Carolina 27709, United States. Curated by ChEMBL					Assay Description Allosteric modulation of CB1 receptor in CD-1 mouse cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding after 60 m...				J Med Chem 60: 7410-7424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00707 BindingDB Entry DOI: 10.7270/Q2XK8J0H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (MOUSE)	BDBM50258782 (CHEMBL4071010) Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2ccc3ccccc3n2)cc1 Show InChI InChI=1S/C22H16ClN3O/c23-17-9-11-18(12-10-17)24-22(27)25-19-6-3-5-16(14-19)21-13-8-15-4-1-2-7-20(15)26-21/h1-14H,(H2,24,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute , Research Triangle Park, North Carolina 27709, United States. Curated by ChEMBL					Assay Description Allosteric modulation of CB1 receptor in CD-1 mouse cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding after 60 m...				J Med Chem 60: 7410-7424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00707 BindingDB Entry DOI: 10.7270/Q2XK8J0H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (MOUSE)	BDBM50258802 (CHEMBL4089126) Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2ccccn2)cc1 Show InChI InChI=1S/C18H14ClN3O/c19-14-7-9-15(10-8-14)21-18(23)22-16-5-3-4-13(12-16)17-6-1-2-11-20-17/h1-12H,(H2,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute , Research Triangle Park, North Carolina 27709, United States. Curated by ChEMBL					Assay Description Allosteric modulation of CB1 receptor in CD-1 mouse cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding after 60 m...				J Med Chem 60: 7410-7424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00707 BindingDB Entry DOI: 10.7270/Q2XK8J0H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (MOUSE)	BDBM50258770 (CHEMBL4100542) Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2ccc(cc2)-c2ccccc2)cc1 Show InChI InChI=1S/C25H19ClN2O/c26-22-13-15-23(16-14-22)27-25(29)28-24-8-4-7-21(17-24)20-11-9-19(10-12-20)18-5-2-1-3-6-18/h1-17H,(H2,27,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute , Research Triangle Park, North Carolina 27709, United States. Curated by ChEMBL					Assay Description Allosteric modulation of CB1 receptor in CD-1 mouse cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding after 60 m...				J Med Chem 60: 7410-7424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00707 BindingDB Entry DOI: 10.7270/Q2XK8J0H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (MOUSE)	BDBM50323040 (1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...) Show SMILES CC(=NOC(=O)Nc1ccccc1)c1cccc(c1)-c1cccs1 |w:2.2| Show InChI InChI=1S/C19H16N2O2S/c1-14(21-23-19(22)20-17-9-3-2-4-10-17)15-7-5-8-16(13-15)18-11-6-12-24-18/h2-13H,1H3,(H,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of mouse brain CB2 receptor				Bioorg Med Chem Lett 20: 4406-11 (2010) Article DOI: 10.1016/j.bmcl.2010.06.050 BindingDB Entry DOI: 10.7270/Q24Q7V5B
					More data for this Ligand-Target Pair