Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 1 (RAT) | BDBM50379862 (CHEMBL2011870) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR1 | Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50177100 (3-Cycloheptyl-9-dimethylamino-3H-pyrido[3',2':4,5]...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Biocampus Curated by ChEMBL | Assay Description Inhibition of rat mGluR1 | Eur J Med Chem 43: 1025-34 (2008) Article DOI: 10.1016/j.ejmech.2007.06.024 BindingDB Entry DOI: 10.7270/Q2V987VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50177080 (3-azepan-1-yl-9-dimethylamino-3H-pyrido[3',2':4,5]...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR1 expressed in 1321N1 cells | Bioorg Med Chem Lett 16: 4936-40 (2006) Article DOI: 10.1016/j.bmcl.2006.06.053 BindingDB Entry DOI: 10.7270/Q2C24W2W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50163617 ((2,3-Dihydro-thieno[2,3-b]quinolin-6-yl)-(4-methox...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibitory concentration against rat metabotropic glutamate receptor 1 | J Med Chem 48: 2134-53 (2005) Article DOI: 10.1021/jm049499o BindingDB Entry DOI: 10.7270/Q2RR2017 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50163592 ((3,4-Dihydro-2H-1-oxa-9-aza-anthracen-6-yl)-(4-met...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibitory concentration against rat metabotropic glutamate receptor 1 | J Med Chem 48: 2134-53 (2005) Article DOI: 10.1021/jm049499o BindingDB Entry DOI: 10.7270/Q2RR2017 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50231750 ((3-ethyl-2-methylquinolin-6-yl)(4-methoxycyclohexy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Organic Synthesis Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphate | J Med Chem 51: 634-47 (2008) Article DOI: 10.1021/jm0611298 BindingDB Entry DOI: 10.7270/Q2QC04B2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50177053 (9-Dimethylamino-3-(4-ethyl-phenyl)-3H-pyrido[3',2'...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biocampus Curated by ChEMBL | Assay Description Inhibition of rat mGluR1 | Eur J Med Chem 43: 1025-34 (2008) Article DOI: 10.1016/j.ejmech.2007.06.024 BindingDB Entry DOI: 10.7270/Q2V987VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50163590 ((2,3-Diethyl-quinolin-6-yl)-(4-methoxy-cyclohexyl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibitory concentration against rat metabotropic glutamate receptor 1 | J Med Chem 48: 2134-53 (2005) Article DOI: 10.1021/jm049499o BindingDB Entry DOI: 10.7270/Q2RR2017 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50163592 ((3,4-Dihydro-2H-1-oxa-9-aza-anthracen-6-yl)-(4-met...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibitory concentration against rat metabotropic glutamate receptor 1 | J Med Chem 48: 2134-53 (2005) Article DOI: 10.1021/jm049499o BindingDB Entry DOI: 10.7270/Q2RR2017 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50163590 ((2,3-Diethyl-quinolin-6-yl)-(4-methoxy-cyclohexyl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibitory concentration against rat metabotropic glutamate receptor 1 | J Med Chem 48: 2134-53 (2005) Article DOI: 10.1021/jm049499o BindingDB Entry DOI: 10.7270/Q2RR2017 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50301804 (5-(1-(2,4-difluorophenyl)-5-methyl-1H-1,2,3-triazo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR1 receptor expressed in CHO cell membranes assessed as inhibition of L-glutamate-induced calcium mobilization by FLIP... | Bioorg Med Chem Lett 19: 5310-3 (2009) Article DOI: 10.1016/j.bmcl.2009.07.145 BindingDB Entry DOI: 10.7270/Q26H4HGN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50163607 (3-ethyl-6-[(4-methoxycyclohexyl)carbonyl]quinoline...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibitory concentration against rat metabotropic glutamate receptor 1 | J Med Chem 48: 2134-53 (2005) Article DOI: 10.1021/jm049499o BindingDB Entry DOI: 10.7270/Q2RR2017 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50177063 (3-(4-Bromo-phenyl)-9-dimethylamino-3H-pyrido[3',2'...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Biocampus Curated by ChEMBL | Assay Description Inhibition of rat mGluR1 | Eur J Med Chem 43: 1025-34 (2008) Article DOI: 10.1016/j.ejmech.2007.06.024 BindingDB Entry DOI: 10.7270/Q2V987VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50129227 (3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 2-isopro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL | Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method. | Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50163613 ((2,3-Dihydro-1H-cyclopenta[b]quinolin-7-yl)-(4-met...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibitory concentration against rat metabotropic glutamate receptor 1 | J Med Chem 48: 2134-53 (2005) Article DOI: 10.1021/jm049499o BindingDB Entry DOI: 10.7270/Q2RR2017 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50163589 ((4-Methoxy-cyclohexyl)-(2-propyl-quinolin-6-yl)-me...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibitory concentration against rat metabotropic glutamate receptor 1 | J Med Chem 48: 2134-53 (2005) Article DOI: 10.1021/jm049499o BindingDB Entry DOI: 10.7270/Q2RR2017 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50163616 ((2-Chloro-3-ethyl-quinolin-6-yl)-(4-methoxy-cycloh...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibitory concentration against rat metabotropic glutamate receptor 1 | J Med Chem 48: 2134-53 (2005) Article DOI: 10.1021/jm049499o BindingDB Entry DOI: 10.7270/Q2RR2017 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50231744 (CHEMBL399160 | NPS 2390 | quinoxaline-2-carboxylic...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Organic Synthesis Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphate | J Med Chem 51: 634-47 (2008) Article DOI: 10.1021/jm0611298 BindingDB Entry DOI: 10.7270/Q2QC04B2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50163616 ((2-Chloro-3-ethyl-quinolin-6-yl)-(4-methoxy-cycloh...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibitory concentration against rat metabotropic glutamate receptor 1 | J Med Chem 48: 2134-53 (2005) Article DOI: 10.1021/jm049499o BindingDB Entry DOI: 10.7270/Q2RR2017 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50177085 (3-Cyclopentyl-9-dimethylamino-3H-pyrido[3',2':4,5]...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Biocampus Curated by ChEMBL | Assay Description Inhibition of rat mGluR1 | Eur J Med Chem 43: 1025-34 (2008) Article DOI: 10.1016/j.ejmech.2007.06.024 BindingDB Entry DOI: 10.7270/Q2V987VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50177097 (9-Dimethylamino-3-p-tolyl-3H-pyrido[3',2':4,5]thie...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Biocampus Curated by ChEMBL | Assay Description Inhibition of rat mGluR1 | Eur J Med Chem 43: 1025-34 (2008) Article DOI: 10.1016/j.ejmech.2007.06.024 BindingDB Entry DOI: 10.7270/Q2V987VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50177053 (9-Dimethylamino-3-(4-ethyl-phenyl)-3H-pyrido[3',2'...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR1 expressed in 1321N1 cells | Bioorg Med Chem Lett 16: 4936-40 (2006) Article DOI: 10.1016/j.bmcl.2006.06.053 BindingDB Entry DOI: 10.7270/Q2C24W2W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50231749 (6-ethyl-5-methyl-3-(1,2,4,5-tetrahydrobenzo[d]azep...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Organic Synthesis Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphate | J Med Chem 51: 634-47 (2008) Article DOI: 10.1021/jm0611298 BindingDB Entry DOI: 10.7270/Q2QC04B2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50163606 (1-(3,4-Dihydro-2H-1-oxa-9-aza-anthracen-6-yl)-2-ph...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibitory concentration against rat metabotropic glutamate receptor 1 | J Med Chem 48: 2134-53 (2005) Article DOI: 10.1021/jm049499o BindingDB Entry DOI: 10.7270/Q2RR2017 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50163609 ((4-Methoxy-cyclohexyl)-(2-methyl-3-propyl-quinolin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibitory concentration against rat metabotropic glutamate receptor 1 | J Med Chem 48: 2134-53 (2005) Article DOI: 10.1021/jm049499o BindingDB Entry DOI: 10.7270/Q2RR2017 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50163611 (1-(3,4-Dihydro-2H-1-oxa-9-aza-anthracen-6-yl)-2-th...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibitory concentration against rat metabotropic glutamate receptor 1 | J Med Chem 48: 2134-53 (2005) Article DOI: 10.1021/jm049499o BindingDB Entry DOI: 10.7270/Q2RR2017 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50163615 ((4-Methoxy-cyclohexyl)-(1-methyl-1,2,3,4-tetrahydr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibitory concentration against rat metabotropic glutamate receptor 1 | J Med Chem 48: 2134-53 (2005) Article DOI: 10.1021/jm049499o BindingDB Entry DOI: 10.7270/Q2RR2017 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50177055 (9-Dimethylamino-3-(3-ethyl-phenyl)-3H-pyrido[3',2'...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Biocampus Curated by ChEMBL | Assay Description Inhibition of rat mGluR1 | Eur J Med Chem 43: 1025-34 (2008) Article DOI: 10.1016/j.ejmech.2007.06.024 BindingDB Entry DOI: 10.7270/Q2V987VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50177080 (3-azepan-1-yl-9-dimethylamino-3H-pyrido[3',2':4,5]...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Biocampus Curated by ChEMBL | Assay Description Inhibition of rat mGluR1 | Eur J Med Chem 43: 1025-34 (2008) Article DOI: 10.1016/j.ejmech.2007.06.024 BindingDB Entry DOI: 10.7270/Q2V987VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50163604 (1-(3-Ethyl-2-methyl-quinolin-6-yl)-2-phenyl-ethano...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibitory concentration against rat metabotropic glutamate receptor 1 | J Med Chem 48: 2134-53 (2005) Article DOI: 10.1021/jm049499o BindingDB Entry DOI: 10.7270/Q2RR2017 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50163599 (Bicyclo[2.2.1]hept-2-yl-(3-ethyl-2-methyl-quinolin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibitory concentration against rat metabotropic glutamate receptor 1 | J Med Chem 48: 2134-53 (2005) Article DOI: 10.1021/jm049499o BindingDB Entry DOI: 10.7270/Q2RR2017 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50163584 ((3-Ethyl-2-iodo-quinolin-6-yl)-(4-methoxy-cyclohex...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibitory concentration against rat metabotropic glutamate receptor 1 | J Med Chem 48: 2134-53 (2005) Article DOI: 10.1021/jm049499o BindingDB Entry DOI: 10.7270/Q2RR2017 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50177059 (3-Cyclooctyl-9-dimethylamino-3H-pyrido[3',2':4,5]t...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Biocampus Curated by ChEMBL | Assay Description Inhibition of rat mGluR1 | Eur J Med Chem 43: 1025-34 (2008) Article DOI: 10.1016/j.ejmech.2007.06.024 BindingDB Entry DOI: 10.7270/Q2V987VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50301520 (4-fluoro-N-(4-(6-(isopropylamino)pyrimidin-4-yl)th...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 13.9 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Radiological Sciences Curated by ChEMBL | Assay Description Displacement of 4-[18F]fluoro-N-[4-(6-(isopropylamino)pyrimidin-4-yl)-1,3-thiazol-2-yl]-N-methylbenzamide from mGluR1 in Sprague-Dawley rat brain hom... | J Med Chem 55: 2342-52 (2012) Article DOI: 10.1021/jm201590g BindingDB Entry DOI: 10.7270/Q2S46T1S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50163620 ((3-Ethyl-2-hydroxy-quinolin-6-yl)-(4-methoxy-cyclo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibitory concentration against rat metabotropic glutamate receptor 1 | J Med Chem 48: 2134-53 (2005) Article DOI: 10.1021/jm049499o BindingDB Entry DOI: 10.7270/Q2RR2017 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50163598 (1-(3-Ethyl-2-methyl-quinolin-6-yl)-2-(4-methoxy-cy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibitory concentration against rat metabotropic glutamate receptor 1 | J Med Chem 48: 2134-53 (2005) Article DOI: 10.1021/jm049499o BindingDB Entry DOI: 10.7270/Q2RR2017 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50177076 (3-(4-Chloro-phenyl)-9-dimethylamino-3H-pyrido[3',2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Biocampus Curated by ChEMBL | Assay Description Inhibition of rat mGluR1 | Eur J Med Chem 43: 1025-34 (2008) Article DOI: 10.1016/j.ejmech.2007.06.024 BindingDB Entry DOI: 10.7270/Q2V987VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50204428 ((S)-4-(3,3-dimethylbutan-2-yl) 2-propyl 3,5-dimeth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of intracellular calcium ion mobilization by FLIPR assay | Bioorg Med Chem Lett 17: 2254-9 (2007) Article DOI: 10.1016/j.bmcl.2007.01.055 BindingDB Entry DOI: 10.7270/Q2FT8KPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50422815 (CHEMBL383107) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL | Assay Description Inhibition of rat mGluR1a in CHO cells by CDP-DAG accumulation method | Bioorg Med Chem Lett 16: 1342-5 (2006) Article DOI: 10.1016/j.bmcl.2005.11.049 BindingDB Entry DOI: 10.7270/Q25B03S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50177065 (9-Dimethylamino-3-(2,4-dimethyl-phenyl)-3H-pyrido[...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Biocampus Curated by ChEMBL | Assay Description Inhibition of rat mGluR1 | Eur J Med Chem 43: 1025-34 (2008) Article DOI: 10.1016/j.ejmech.2007.06.024 BindingDB Entry DOI: 10.7270/Q2V987VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50129246 (3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 2-tert-b...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL | Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method. | Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50163586 ((3-Ethyl-2-methoxy-quinolin-6-yl)-(4-methoxy-cyclo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibitory concentration against rat metabotropic glutamate receptor 1 | J Med Chem 48: 2134-53 (2005) Article DOI: 10.1021/jm049499o BindingDB Entry DOI: 10.7270/Q2RR2017 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50163586 ((3-Ethyl-2-methoxy-quinolin-6-yl)-(4-methoxy-cyclo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibitory concentration against rat metabotropic glutamate receptor 1 | J Med Chem 48: 2134-53 (2005) Article DOI: 10.1021/jm049499o BindingDB Entry DOI: 10.7270/Q2RR2017 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50422824 (CHEMBL204802) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL | Assay Description Inhibition of rat mGluR1a in CHO cells by CDP-DAG accumulation method | Bioorg Med Chem Lett 16: 1342-5 (2006) Article DOI: 10.1016/j.bmcl.2005.11.049 BindingDB Entry DOI: 10.7270/Q25B03S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50177079 (9-dimethylamino-3-phenyl-3H-pyrido[3',2':4,5]thien...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Biocampus Curated by ChEMBL | Assay Description Inhibition of rat mGluR1 | Eur J Med Chem 43: 1025-34 (2008) Article DOI: 10.1016/j.ejmech.2007.06.024 BindingDB Entry DOI: 10.7270/Q2V987VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50422826 (CHEMBL377503) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL | Assay Description Inhibition of rat mGluR1a in CHO cells by CDP-DAG accumulation method | Bioorg Med Chem Lett 16: 1342-5 (2006) Article DOI: 10.1016/j.bmcl.2005.11.049 BindingDB Entry DOI: 10.7270/Q25B03S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50422825 (CHEMBL444359) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL | Assay Description Inhibition of rat mGluR1a in CHO cells by CDP-DAG accumulation method | Bioorg Med Chem Lett 16: 1342-5 (2006) Article DOI: 10.1016/j.bmcl.2005.11.049 BindingDB Entry DOI: 10.7270/Q25B03S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50190236 (9-dimethylamino-3-(3-fluoro-4-methyl-phenyl)-3H-py...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR1 expressed in 1321N1 cells | Bioorg Med Chem Lett 16: 4936-40 (2006) Article DOI: 10.1016/j.bmcl.2006.06.053 BindingDB Entry DOI: 10.7270/Q2C24W2W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50177078 (9-Dimethylamino-3-(4-fluoro-phenyl)-3H-pyrido[3',2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Biocampus Curated by ChEMBL | Assay Description Inhibition of rat mGluR1 | Eur J Med Chem 43: 1025-34 (2008) Article DOI: 10.1016/j.ejmech.2007.06.024 BindingDB Entry DOI: 10.7270/Q2V987VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50422817 (CHEMBL380698) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL | Assay Description Inhibition of rat mGluR1a in CHO cells by CDP-DAG accumulation method | Bioorg Med Chem Lett 16: 1342-5 (2006) Article DOI: 10.1016/j.bmcl.2005.11.049 BindingDB Entry DOI: 10.7270/Q25B03S5 | |||||||||||
More data for this Ligand-Target Pair |
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