Compile Data Set for Download or QSAR

Found 51 hits of ic50 data for polymerid = 50000092,50001088   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lutropin-choriogonadotropic hormone receptor (Rattus norvegicus)	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at rat luteinizing hormone receptor expressed in rat ovary granulosa GLHR15 cell suspension assessed as reduction in agonist-indu...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Rattus norvegicus)	BDBM50505783 (CHEMBL4458424) Show SMILES Fc1ccc(Oc2ncc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(F)cc3)cn2)cc1 |r| Show InChI InChI=1S/C25H19F2N5O2/c26-17-5-3-16(4-6-17)23-21-2-1-12-28-22(21)11-13-32(23)25(33)31-19-14-29-24(30-15-19)34-20-9-7-18(27)8-10-20/h1-10,12,14-15,23H,11,13H2,(H,31,33)/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at rat luteinizing hormone receptor expressed in rat ovary granulosa GLHR15 cell suspension assessed as reduction in agonist-indu...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505809 (CHEMBL4460075) Show SMILES Fc1ccc(NC(=O)N2CCc3sccc3C2c2ccc(Cl)cc2)cc1OC(F)(F)F Show InChI InChI=1S/C21H15ClF4N2O2S/c22-13-3-1-12(2-4-13)19-15-8-10-31-18(15)7-9-28(19)20(29)27-14-5-6-16(23)17(11-14)30-21(24,25)26/h1-6,8,10-11,19H,7,9H2,(H,27,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50383229 (CHEMBL2032175) Show SMILES Clc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1ccccc1 Show InChI InChI=1S/C20H17ClN2OS/c21-15-8-6-14(7-9-15)19-17-11-13-25-18(17)10-12-23(19)20(24)22-16-4-2-1-3-5-16/h1-9,11,13,19H,10,12H2,(H,22,24)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Negative allosteric modulation of human luteinizing hormone receptor assessed as reduction in glycoprotein human luteinizing hormone-induced agonist ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505791 (CHEMBL4587440) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(F)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21F2N3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505799 (CHEMBL4573509) Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C21H19ClN2O2S/c1-26-17-8-2-14(3-9-17)20-18-11-13-27-19(18)10-12-24(20)21(25)23-16-6-4-15(22)5-7-16/h2-9,11,13,20H,10,12H2,1H3,(H,23,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505796 (CHEMBL4531781) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4sccc4C3c3ccc(Cl)cc3)cc2)cc1 Show InChI InChI=1S/C26H20ClFN2O2S/c27-18-3-1-17(2-4-18)25-23-14-16-33-24(23)13-15-30(25)26(31)29-20-7-11-22(12-8-20)32-21-9-5-19(28)6-10-21/h1-12,14,16,25H,13,15H2,(H,29,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	127	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505785 (CHEMBL4443605) Show SMILES Fc1ccc(NC(=O)N2CCc3sccc3C2c2ccc(Cl)cc2)cc1Cl Show InChI InChI=1S/C20H15Cl2FN2OS/c21-13-3-1-12(2-4-13)19-15-8-10-27-18(15)7-9-25(19)20(26)24-14-5-6-17(23)16(22)11-14/h1-6,8,10-11,19H,7,9H2,(H,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	174	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505783 (CHEMBL4458424) Show SMILES Fc1ccc(Oc2ncc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(F)cc3)cn2)cc1 |r| Show InChI InChI=1S/C25H19F2N5O2/c26-17-5-3-16(4-6-17)23-21-2-1-12-28-22(21)11-13-32(23)25(33)31-19-14-29-24(30-15-19)34-20-9-7-18(27)8-10-20/h1-10,12,14-15,23H,11,13H2,(H,31,33)/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505811 (CHEMBL4461980) Show SMILES COc1cc(NC(=O)N2CCc3sccc3[C@@H]2c2ccccc2)cc(OC)c1 |r| Show InChI InChI=1S/C22H22N2O3S/c1-26-17-12-16(13-18(14-17)27-2)23-22(25)24-10-8-20-19(9-11-28-20)21(24)15-6-4-3-5-7-15/h3-7,9,11-14,21H,8,10H2,1-2H3,(H,23,25)/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	193	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Negative allosteric modulation of human luteinizing hormone receptor assessed as reduction in glycoprotein human luteinizing hormone-induced agonist ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505797 (CHEMBL4522381) Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cc(OC)cc(OC)c1 Show InChI InChI=1S/C23H24N2O4S/c1-27-17-6-4-15(5-7-17)22-20-9-11-30-21(20)8-10-25(22)23(26)24-16-12-18(28-2)14-19(13-16)29-3/h4-7,9,11-14,22H,8,10H2,1-3H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	207	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Rattus norvegicus)	BDBM50505793 (CHEMBL4593222) Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C21H18Cl2N2O2S/c1-27-17-4-2-13(3-5-17)20-18-7-9-28-19(18)6-8-25(20)21(26)24-16-11-14(22)10-15(23)12-16/h2-5,7,9-12,20H,6,8H2,1H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	212	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at rat luteinizing hormone receptor expressed in rat ovary granulosa GLHR15 cell suspension assessed as reduction in agonist-indu...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505798 (CHEMBL4581889) Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cccc(Cl)c1 Show InChI InChI=1S/C21H19ClN2O2S/c1-26-17-7-5-14(6-8-17)20-18-10-12-27-19(18)9-11-24(20)21(25)23-16-4-2-3-15(22)13-16/h2-8,10,12-13,20H,9,11H2,1H3,(H,23,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	275	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505812 (CHEMBL4555151) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(F)cc3)cn2)cc1 |r| Show InChI InChI=1S/C26H20F2N4O2/c27-18-5-3-17(4-6-18)25-22-2-1-14-29-23(22)13-15-32(25)26(33)31-20-9-12-24(30-16-20)34-21-10-7-19(28)8-11-21/h1-12,14,16,25H,13,15H2,(H,31,33)/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	312	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505795 (CHEMBL4579421) Show SMILES Clc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cccc(Oc2ccccc2)c1 Show InChI InChI=1S/C26H21ClN2O2S/c27-19-11-9-18(10-12-19)25-23-14-16-32-24(23)13-15-29(25)26(30)28-20-5-4-8-22(17-20)31-21-6-2-1-3-7-21/h1-12,14,16-17,25H,13,15H2,(H,28,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	332	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505793 (CHEMBL4593222) Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C21H18Cl2N2O2S/c1-27-17-4-2-13(3-5-17)20-18-7-9-28-19(18)6-8-25(20)21(26)24-16-11-14(22)10-15(23)12-16/h2-5,7,9-12,20H,6,8H2,1H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	378	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505789 (CHEMBL4471621) Show SMILES COc1ccc(cc1)[C@@H]1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 |r| Show InChI InChI=1S/C21H18Cl2N2O2S/c1-27-17-4-2-13(3-5-17)20-18-7-9-28-19(18)6-8-25(20)21(26)24-16-11-14(22)10-15(23)12-16/h2-5,7,9-12,20H,6,8H2,1H3,(H,24,26)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	403	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Rattus norvegicus)	BDBM50505789 (CHEMBL4471621) Show SMILES COc1ccc(cc1)[C@@H]1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 |r| Show InChI InChI=1S/C21H18Cl2N2O2S/c1-27-17-4-2-13(3-5-17)20-18-7-9-28-19(18)6-8-25(20)21(26)24-16-11-14(22)10-15(23)12-16/h2-5,7,9-12,20H,6,8H2,1H3,(H,24,26)/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	412	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at rat luteinizing hormone receptor expressed in rat ovary granulosa GLHR15 cell suspension assessed as reduction in agonist-indu...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505804 (CHEMBL4590976) Show SMILES Clc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C20H15Cl3N2OS/c21-13-3-1-12(2-4-13)19-17-6-8-27-18(17)5-7-25(19)20(26)24-16-10-14(22)9-15(23)11-16/h1-4,6,8-11,19H,5,7H2,(H,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	486	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505813 (CHEMBL4580951) Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cc(C)cc(C)c1 Show InChI InChI=1S/C23H24N2O2S/c1-15-12-16(2)14-18(13-15)24-23(26)25-10-8-21-20(9-11-28-21)22(25)17-4-6-19(27-3)7-5-17/h4-7,9,11-14,22H,8,10H2,1-3H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Negative allosteric modulation of human luteinizing hormone receptor assessed as reduction in Org 43553-induced agonist activity preincubated for 20 ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Negative allosteric modulation of human luteinizing hormone receptor assessed as reduction in Org 43553-induced agonist activity preincubated for 20 ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Negative allosteric modulation of human luteinizing hormone receptor assessed as reduction in Org 43553-induced agonist activity preincubated for 20 ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Negative allosteric modulation of human luteinizing hormone receptor assessed as reduction in Org 43553-induced agonist activity preincubated for 20 ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505786 (CHEMBL4560733) Show SMILES Clc1cc(Cl)cc(NC(=O)N2CCc3sccc3C2c2ccccc2)c1 Show InChI InChI=1S/C20H16Cl2N2OS/c21-14-10-15(22)12-16(11-14)23-20(25)24-8-6-18-17(7-9-26-18)19(24)13-4-2-1-3-5-13/h1-5,7,9-12,19H,6,8H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505794 (CHEMBL4456365) Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1ccc(F)c(c1)C(N)=O Show InChI InChI=1S/C22H20FN3O3S/c1-29-15-5-2-13(3-6-15)20-16-9-11-30-19(16)8-10-26(20)22(28)25-14-4-7-18(23)17(12-14)21(24)27/h2-7,9,11-12,20H,8,10H2,1H3,(H2,24,27)(H,25,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Negative allosteric modulation of human luteinizing hormone receptor assessed as reduction in Org 43553-induced agonist activity preincubated for 20 ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505808 (CHEMBL4464604) Show SMILES Fc1ccc(cc1F)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C20H14Cl2F2N2OS/c21-12-8-13(22)10-14(9-12)25-20(27)26-5-3-18-15(4-6-28-18)19(26)11-1-2-16(23)17(24)7-11/h1-2,4,6-10,19H,3,5H2,(H,25,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Negative allosteric modulation of human luteinizing hormone receptor assessed as reduction in glycoprotein human luteinizing hormone-induced agonist ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Negative allosteric modulation of human luteinizing hormone receptor assessed as reduction in glycoprotein human luteinizing hormone-induced agonist ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50256858 (CHEMBL474041 | Cyclopentyl-carbamic acid [1,1',3',...) Show SMILES O=C(NC1CCCC1)Oc1cc(cc(c1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C24H23NO2/c26-24(25-22-13-7-8-14-22)27-23-16-20(18-9-3-1-4-10-18)15-21(17-23)19-11-5-2-6-12-19/h1-6,9-12,15-17,22H,7-8,13-14H2,(H,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]Org43553 from human luteinizing hormone receptor expressed in CHOK1 cells				J Med Chem 52: 2036-42 (2009) Article DOI: 10.1021/jm801561h BindingDB Entry DOI: 10.7270/Q2G73DMJ
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505810 (CHEMBL4551301) Show SMILES Clc1cc(Cl)cc(NC(=O)N2CCc3sccc3C2c2ccc(=O)[nH]c2)c1 Show InChI InChI=1S/C19H15Cl2N3O2S/c20-12-7-13(21)9-14(8-12)23-19(26)24-5-3-16-15(4-6-27-16)18(24)11-1-2-17(25)22-10-11/h1-2,4,6-10,18H,3,5H2,(H,22,25)(H,23,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Negative allosteric modulation of human luteinizing hormone receptor assessed as reduction in glycoprotein human luteinizing hormone-induced agonist ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505802 (CHEMBL4468163) Show SMILES Cc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C21H18Cl2N2OS/c1-13-2-4-14(5-3-13)20-18-7-9-27-19(18)6-8-25(20)21(26)24-17-11-15(22)10-16(23)12-17/h2-5,7,9-12,20H,6,8H2,1H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505800 (CHEMBL4588196) Show SMILES Fc1cccc(c1)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C20H15Cl2FN2OS/c21-13-9-14(22)11-16(10-13)24-20(26)25-6-4-18-17(5-7-27-18)19(25)12-2-1-3-15(23)8-12/h1-3,5,7-11,19H,4,6H2,(H,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505801 (CHEMBL4570127) Show SMILES Fc1ccccc1C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C20H15Cl2FN2OS/c21-12-9-13(22)11-14(10-12)24-20(26)25-7-5-18-16(6-8-27-18)19(25)15-3-1-2-4-17(15)23/h1-4,6,8-11,19H,5,7H2,(H,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505792 (CHEMBL4471875) Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=S)Nc1cc(OC)cc(OC)c1 Show InChI InChI=1S/C23H24N2O3S2/c1-26-17-6-4-15(5-7-17)22-20-9-11-30-21(20)8-10-25(22)23(29)24-16-12-18(27-2)14-19(13-16)28-3/h4-7,9,11-14,22H,8,10H2,1-3H3,(H,24,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505815 (CHEMBL4468307) Show SMILES FC(F)(F)c1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C21H15Cl2F3N2OS/c22-14-9-15(23)11-16(10-14)27-20(29)28-7-5-18-17(6-8-30-18)19(28)12-1-3-13(4-2-12)21(24,25)26/h1-4,6,8-11,19H,5,7H2,(H,27,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Rattus norvegicus)	BDBM50505788 (CHEMBL4449797) Show SMILES COc1ccc(cc1)[C@H]1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 |r| Show InChI InChI=1S/C21H18Cl2N2O2S/c1-27-17-4-2-13(3-5-17)20-18-7-9-28-19(18)6-8-25(20)21(26)24-16-11-14(22)10-15(23)12-16/h2-5,7,9-12,20H,6,8H2,1H3,(H,24,26)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at rat luteinizing hormone receptor expressed in rat ovary granulosa GLHR15 cell suspension assessed as reduction in agonist-indu...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505816 (CHEMBL4573451) Show SMILES Clc1cc(Cl)cc(NC(=O)N2CCc3sccc3C2c2ccncc2)c1 Show InChI InChI=1S/C19H15Cl2N3OS/c20-13-9-14(21)11-15(10-13)23-19(25)24-7-3-17-16(4-8-26-17)18(24)12-1-5-22-6-2-12/h1-2,4-6,8-11,18H,3,7H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505788 (CHEMBL4449797) Show SMILES COc1ccc(cc1)[C@H]1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 |r| Show InChI InChI=1S/C21H18Cl2N2O2S/c1-27-17-4-2-13(3-5-17)20-18-7-9-28-19(18)6-8-25(20)21(26)24-16-11-14(22)10-15(23)12-16/h2-5,7,9-12,20H,6,8H2,1H3,(H,24,26)/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505806 (CHEMBL4471103) Show SMILES Clc1cc(Cl)cc(NC(=O)N2CCc3sccc3C2c2cccnc2)c1 Show InChI InChI=1S/C19H15Cl2N3OS/c20-13-8-14(21)10-15(9-13)23-19(25)24-6-3-17-16(4-7-26-17)18(24)12-2-1-5-22-11-12/h1-2,4-5,7-11,18H,3,6H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505790 (CHEMBL4553576) Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Cc1cc(C)cc(C)c1 Show InChI InChI=1S/C24H25NO2S/c1-16-12-17(2)14-18(13-16)15-23(26)25-10-8-22-21(9-11-28-22)24(25)19-4-6-20(27-3)7-5-19/h4-7,9,11-14,24H,8,10,15H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505805 (CHEMBL4563783) Show SMILES Clc1cc(Cl)cc(NC(=O)N2CCc3sccc3C2c2ccccn2)c1 Show InChI InChI=1S/C19H15Cl2N3OS/c20-12-9-13(21)11-14(10-12)23-19(25)24-7-4-17-15(5-8-26-17)18(24)16-3-1-2-6-22-16/h1-3,5-6,8-11,18H,4,7H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505814 (CHEMBL4458027) Show SMILES NC(=O)c1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C21H17Cl2N3O2S/c22-14-9-15(23)11-16(10-14)25-21(28)26-7-5-18-17(6-8-29-18)19(26)12-1-3-13(4-2-12)20(24)27/h1-4,6,8-11,19H,5,7H2,(H2,24,27)(H,25,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505784 (CHEMBL4464888) Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1ccc(F)c(c1)N1CCS(=O)(=O)CC1 Show InChI InChI=1S/C25H26FN3O4S2/c1-33-19-5-2-17(3-6-19)24-20-9-13-34-23(20)8-10-29(24)25(30)27-18-4-7-21(26)22(16-18)28-11-14-35(31,32)15-12-28/h2-7,9,13,16,24H,8,10-12,14-15H2,1H3,(H,27,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505803 (CHEMBL4524393) Show SMILES CC(C)c1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C23H22Cl2N2OS/c1-14(2)15-3-5-16(6-4-15)22-20-8-10-29-21(20)7-9-27(22)23(28)26-19-12-17(24)11-18(25)13-19/h3-6,8,10-14,22H,7,9H2,1-2H3,(H,26,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair

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