Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50090529 (2-[1-(Naphthalene-1-sulfonyl)-1H-indol-6-yl]-octah...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7.20 | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Antagonistic activity of the compound evaluated in adenylyl cyclase assay | Bioorg Med Chem Lett 10: 1719-21 (2000) BindingDB Entry DOI: 10.7270/Q2BP021W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50128187 ((1R,3R)-3-(6-Amino-purin-9-yl)-cyclopentanecarboxy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50128192 ((1S,3R)-2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50128210 ((1R,3R)-2-[3-(6-Amino-purin-9-yl)-cyclopentyl]-N-h...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50128207 ((1S,3S)-2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Rattus norvegicus) | BDBM50140057 (2-Hydroxymethyl-5-(6-methylamino-purin-9-yl)-tetra...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Compound was evaluated for inhibition of adenylate cyclase from rat brain | J Med Chem 47: 1207-13 (2004) Article DOI: 10.1021/jm0303599 BindingDB Entry DOI: 10.7270/Q2Q52QC7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50128209 ((1R,3S)-2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Rattus norvegicus) | BDBM50370376 (CHEMBL1229920) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Compound was evaluated for inhibition of adenylate cyclase from rat brain | J Med Chem 47: 1207-13 (2004) Article DOI: 10.1021/jm0303599 BindingDB Entry DOI: 10.7270/Q2Q52QC7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50128203 ((1R,3S)-3-(6-Amino-purin-9-yl)-cyclopentanecarboxy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50128199 ((1S,3S)-4-(6-Amino-purin-9-yl)-cyclopent-2-enecarb...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119826 (5-(6-Amino-purin-9-yl)-pentanoic acid hydroxyamide...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against type V Adenyl Cyclase enzyme | Bioorg Med Chem Lett 12: 3089-92 (2002) BindingDB Entry DOI: 10.7270/Q2T43SFX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119826 (5-(6-Amino-purin-9-yl)-pentanoic acid hydroxyamide...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119826 (5-(6-Amino-purin-9-yl)-pentanoic acid hydroxyamide...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cells | Bioorg Med Chem Lett 12: 3085-8 (2002) BindingDB Entry DOI: 10.7270/Q2XW4J5B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119832 (4-(6-Amino-purin-9-yl)-N-hydroxy-butyramide | CHEM...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119832 (4-(6-Amino-purin-9-yl)-N-hydroxy-butyramide | CHEM...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 7.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against type V Adenyl Cyclase enzyme | Bioorg Med Chem Lett 12: 3089-92 (2002) BindingDB Entry DOI: 10.7270/Q2T43SFX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119832 (4-(6-Amino-purin-9-yl)-N-hydroxy-butyramide | CHEM...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 7.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cells | Bioorg Med Chem Lett 12: 3085-8 (2002) BindingDB Entry DOI: 10.7270/Q2XW4J5B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50128188 ((1S,3R)-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl]-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50128206 ((1S,3S)-2-[3-(6-Amino-purin-9-yl)-cyclopentyl]-N-h...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119858 (2-[(S)-3-((S)-6-Amino-purin-9-yl)-cyclopentyloxy]-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Type V Adenyl Cyclase enzyme | Bioorg Med Chem Lett 12: 3089-92 (2002) BindingDB Entry DOI: 10.7270/Q2T43SFX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119858 (2-[(S)-3-((S)-6-Amino-purin-9-yl)-cyclopentyloxy]-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Type V Adenyl Cyclase enzyme | Bioorg Med Chem Lett 12: 3089-92 (2002) BindingDB Entry DOI: 10.7270/Q2T43SFX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50128191 (2-[3-(6-Amino-purin-9-yl)-cyclopentyloxy]-N-hydrox...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119855 (2-{[(1S,4R)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Type V Adenyl Cyclase enzyme | Bioorg Med Chem Lett 12: 3089-92 (2002) BindingDB Entry DOI: 10.7270/Q2T43SFX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50128205 (2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyloxy]-N-h...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119855 (2-{[(1S,4R)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Type V Adenyl Cyclase enzyme | Bioorg Med Chem Lett 12: 3089-92 (2002) BindingDB Entry DOI: 10.7270/Q2T43SFX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Rattus norvegicus) | BDBM50025883 ((2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Compound was evaluated for inhibition of adenylate cyclase from rat brain | J Med Chem 47: 1207-13 (2004) Article DOI: 10.1021/jm0303599 BindingDB Entry DOI: 10.7270/Q2Q52QC7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119844 (2-{[2-(6-Amino-purin-9-yl)-ethyl]-methyl-amino}-N-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.53E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cells | Bioorg Med Chem Lett 12: 3085-8 (2002) BindingDB Entry DOI: 10.7270/Q2XW4J5B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50128204 ((1R,3R)-2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.63E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50128202 ((1R,3S)-2-[3-(6-Amino-purin-9-yl)-cyclopentyl]-N-h...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50128195 ((1R,3R)-[3-(6-Amino-purin-9-yl)-cyclopentyl]-aceti...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.88E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119842 (6-(6-Amino-purin-9-yl)-hexanoic acid hydroxyamide ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.54E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cells | Bioorg Med Chem Lett 12: 3085-8 (2002) BindingDB Entry DOI: 10.7270/Q2XW4J5B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119842 (6-(6-Amino-purin-9-yl)-hexanoic acid hydroxyamide ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.54E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119842 (6-(6-Amino-purin-9-yl)-hexanoic acid hydroxyamide ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.54E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against type V Adenyl Cyclase enzyme | Bioorg Med Chem Lett 12: 3089-92 (2002) BindingDB Entry DOI: 10.7270/Q2T43SFX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50128197 ((1S,3R)-2-[3-(6-Amino-purin-9-yl)-cyclopentyl]-N-h...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50128201 ((1S,3R)-3-(6-Amino-purin-9-yl)-cyclopentanecarboxy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >7.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119853 (2-{[(1S,4S)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 7.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Type V Adenyl Cyclase enzyme | Bioorg Med Chem Lett 12: 3089-92 (2002) BindingDB Entry DOI: 10.7270/Q2T43SFX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50128190 ((1S,3S)-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl]-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119860 (2-{[(1S,4R)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 7.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Type V Adenyl Cyclase enzyme | Bioorg Med Chem Lett 12: 3089-92 (2002) BindingDB Entry DOI: 10.7270/Q2T43SFX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50128186 ((1S,3S)-3-(6-Amino-purin-9-yl)-cyclopentanecarboxy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119857 (CHEMBL108067 | [(S)-3-((S)-6-Amino-purin-9-yl)-cyc...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 7.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Type V Adenyl Cyclase enzyme | Bioorg Med Chem Lett 12: 3089-92 (2002) BindingDB Entry DOI: 10.7270/Q2T43SFX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119821 (2-[3-(6-Amino-purin-9-yl)-propoxy]-N-hydroxy-aceta...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 9.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against type V Adenyl Cyclase enzyme | Bioorg Med Chem Lett 12: 3089-92 (2002) BindingDB Entry DOI: 10.7270/Q2T43SFX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119821 (2-[3-(6-Amino-purin-9-yl)-propoxy]-N-hydroxy-aceta...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 9.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cells | Bioorg Med Chem Lett 12: 3085-8 (2002) BindingDB Entry DOI: 10.7270/Q2XW4J5B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119854 (2-{[(1R,4S)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 9.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Type V Adenyl Cyclase enzyme | Bioorg Med Chem Lett 12: 3089-92 (2002) BindingDB Entry DOI: 10.7270/Q2T43SFX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119861 (2-{[(1R,4S)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 9.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Type V Adenyl Cyclase enzyme | Bioorg Med Chem Lett 12: 3089-92 (2002) BindingDB Entry DOI: 10.7270/Q2T43SFX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Rattus norvegicus) | BDBM50008363 (5-(6-Amino-2-fluoro-purin-9-yl)-2-hydroxymethyl-te...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Compound was evaluated for inhibition of adenylate cyclase from rat brain | J Med Chem 47: 1207-13 (2004) Article DOI: 10.1021/jm0303599 BindingDB Entry DOI: 10.7270/Q2Q52QC7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50128189 ((1S,3S)-[3-(6-Amino-purin-9-yl)-cyclopentyl]-aceti...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50128194 ((1R,3R)-4-(6-Amino-purin-9-yl)-cyclopent-2-enecarb...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119854 (2-{[(1R,4S)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.02E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Type V Adenyl Cyclase enzyme | Bioorg Med Chem Lett 12: 3089-92 (2002) BindingDB Entry DOI: 10.7270/Q2T43SFX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119851 (2-[(R)-3-((R)-6-Amino-purin-9-yl)-cyclopentyloxy]-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Type V Adenyl Cyclase enzyme | Bioorg Med Chem Lett 12: 3089-92 (2002) BindingDB Entry DOI: 10.7270/Q2T43SFX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119829 (CHEMBL104969 | [3-(6-Amino-purin-9-yl)-propoxy]-ac...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.41E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cells | Bioorg Med Chem Lett 12: 3085-8 (2002) BindingDB Entry DOI: 10.7270/Q2XW4J5B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50128211 ((1S,3R)-4-(6-Amino-purin-9-yl)-cyclopent-2-enecarb...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.88E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair |
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