Compile Data Set for Download or QSAR

Found 162 hits of ic50 data for polymerid = 50001108   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM50526737 (CHEMBL4528500 | US10807974, Example 82 | US1099508...) Show SMILES Cc1ccc(cc1)-c1cc(ccc1S(C)(=O)=O)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C19H19NO4S3/c1-13-3-5-14(6-4-13)17-11-16(8-9-18(17)26(2,21)22)27(23,24)19-10-7-15(12-20)25-19/h3-11H,12,20H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<180	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description Cell Culture and TransfectionAll cell lines used in this study was purchased from American Type Culture Collection (ATCC). Mycoplasma contamination w...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM50526721 (CHEMBL4444163 | US10807974, Example 111 | US109950...) Show SMILES CCc1cc(cc(c1)S(=O)(=O)c1cnc(CN)s1)-c1cnn(C)c1 Show InChI InChI=1S/C16H18N4O2S2/c1-3-11-4-12(13-8-19-20(2)10-13)6-14(5-11)24(21,22)16-9-18-15(7-17)23-16/h4-6,8-10H,3,7,17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description Cell Culture and TransfectionAll cell lines used in this study was purchased from American Type Culture Collection (ATCC). Mycoplasma contamination w...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469007 (US10807974, Example 16 | US10995088, Example 16 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1ccc(cc1)S(=O)(=O)CCO Show InChI InChI=1S/C13H15NO5S3/c14-9-10-1-6-13(20-10)22(18,19)12-4-2-11(3-5-12)21(16,17)8-7-15/h1-6,15H,7-9,14H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM50058655 (1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...) Show SMILES CCN(CC)C(=S)SSC(=S)N(CC)CC Show InChI InChI=1S/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Hungarian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human LOX expressed in HEK293 cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additi...				Bioorg Med Chem Lett 28: 3113-3118 (2018) Article DOI: 10.1016/j.bmcl.2018.07.001 BindingDB Entry DOI: 10.7270/Q28P6366
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469005 (US10807974, Example 9 | US10995088, Example 9 | US...) Show SMILES CS(=O)(=O)c1cccc(c1)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C12H13NO4S3/c1-19(14,15)10-3-2-4-11(7-10)20(16,17)12-6-5-9(8-13)18-12/h2-7H,8,13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469011 (US10807974, Example 27 | US10995088, Example 27 | ...) Show SMILES CCNCCS(=O)(=O)c1ccc(cc1)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C15H20N2O4S3/c1-2-17-9-10-23(18,19)13-4-6-14(7-5-13)24(20,21)15-8-3-12(11-16)22-15/h3-8,17H,2,9-11,16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469032 (US10807974, Example 43 | US10995088, Example 43 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCC[C@H]1CO |r| Show InChI InChI=1S/C16H20N2O5S3/c17-10-13-6-7-16(24-13)25(20,21)14-4-1-5-15(9-14)26(22,23)18-8-2-3-12(18)11-19/h1,4-7,9,12,19H,2-3,8,10-11,17H2/t12-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469023 (US10807974, Example 39 | US10995088, Example 39 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1ccc(cc1)S(=O)(=O)CCCO Show InChI InChI=1S/C14H17NO5S3/c15-10-11-2-7-14(21-11)23(19,20)13-5-3-12(4-6-13)22(17,18)9-1-8-16/h2-7,16H,1,8-10,15H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469019 (US10807974, Example 35 | US10995088, Example 35 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1ccc(cc1)S(=O)(=O)CCN1CCCNCC1 Show InChI InChI=1S/C18H25N3O4S3/c19-14-15-2-7-18(26-15)28(24,25)17-5-3-16(4-6-17)27(22,23)13-12-21-10-1-8-20-9-11-21/h2-7,20H,1,8-14,19H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469008 (US10807974, Example 17 | US10995088, Example 17 | ...) Show SMILES CN(C)CCS(=O)(=O)c1ccc(cc1)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C15H20N2O4S3/c1-17(2)9-10-23(18,19)13-4-6-14(7-5-13)24(20,21)15-8-3-12(11-16)22-15/h3-8H,9-11,16H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469024 (US10807974, Example 40 | US10995088, Example 40 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1ccc(cc1)S(=O)(=O)CCCN=[N+]=[N-] Show InChI InChI=1S/C14H16N4O4S3/c15-10-11-2-7-14(23-11)25(21,22)13-5-3-12(4-6-13)24(19,20)9-1-8-17-18-16/h2-7H,1,8-10,15H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469004 (US10807974, Example 5 | US10995088, Example 5 | US...) Show SMILES CS(=O)(=O)c1ccc(cc1)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C12H13NO4S3/c1-19(14,15)10-3-5-11(6-4-10)20(16,17)12-7-2-9(8-13)18-12/h2-7H,8,13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469027 (US10807974, Example 12 | US10995088, Example 12 | ...) Show SMILES CN(C)S(=O)(=O)c1ccc(cc1)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C13H16N2O4S3/c1-15(2)22(18,19)12-6-4-11(5-7-12)21(16,17)13-8-3-10(9-14)20-13/h3-8H,9,14H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469018 (US10807974, Example 34 | US10995088, Example 34 | ...) Show SMILES CS(=O)(=O)N1CCN(CCS(=O)(=O)c2ccc(cc2)S(=O)(=O)c2ccc(CN)s2)CC1 Show InChI InChI=1S/C18H25N3O6S4/c1-29(22,23)21-10-8-20(9-11-21)12-13-30(24,25)16-3-5-17(6-4-16)31(26,27)18-7-2-15(14-19)28-18/h2-7H,8-14,19H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) Show SMILES NCCC#N Show InChI InChI=1S/C3H6N2/c4-2-1-3-5/h1-2,4H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
PharmAkea Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant human LOX expressed in HEK cells assessed as reduction in H2O2 production using DAP as substrate preincubated f...				ACS Med Chem Lett 8: 423-427 (2017) Article DOI: 10.1021/acsmedchemlett.7b00014 BindingDB Entry DOI: 10.7270/Q2542QV6
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) Show SMILES NCCC#N Show InChI InChI=1S/C3H6N2/c4-2-1-3-5/h1-2,4H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
PharmAkea Therapeutics Curated by ChEMBL					Assay Description Inhibition of human LOX expressed in HEK cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs foll...				J Med Chem 60: 4403-4423 (2017) Article DOI: 10.1021/acs.jmedchem.7b00345 BindingDB Entry DOI: 10.7270/Q2QV3Q0K
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469010 (US10807974, Example 26 | US10995088, Example 26 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1ccc(cc1)S(=O)(=O)CCN1CCCC1 Show InChI InChI=1S/C17H22N2O4S3/c18-13-14-3-8-17(24-14)26(22,23)16-6-4-15(5-7-16)25(20,21)12-11-19-9-1-2-10-19/h3-8H,1-2,9-13,18H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469022 (US10807974, Example 38 | US10995088, Example 38 | ...) Show SMILES CC(=O)N1CCCN(CCS(=O)(=O)c2ccc(cc2)S(=O)(=O)c2ccc(CN)s2)CC1 Show InChI InChI=1S/C20H27N3O5S3/c1-16(24)23-10-2-9-22(11-12-23)13-14-30(25,26)18-4-6-19(7-5-18)31(27,28)20-8-3-17(15-21)29-20/h3-8H,2,9-15,21H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469029 (US10807974, Example 14 | US10807974, Example 42 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C15H18N2O4S3/c16-11-12-6-7-15(22-12)23(18,19)13-4-3-5-14(10-13)24(20,21)17-8-1-2-9-17/h3-7,10H,1-2,8-9,11,16H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469025 (US10807974, Example 41 | US10995088, Example 41 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1ccc(cc1)S(=O)(=O)CCCN1CCCC1 Show InChI InChI=1S/C18H24N2O4S3/c19-14-15-4-9-18(25-15)27(23,24)17-7-5-16(6-8-17)26(21,22)13-3-12-20-10-1-2-11-20/h4-9H,1-3,10-14,19H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469107 (US10807974, Example 126 | US10995088, Example 126 ...) Show SMILES NCc1ncc(s1)S(=O)(=O)c1cc(cc(c1)-c1ccccc1)C(O)=O Show InChI InChI=1S/C17H14N2O4S2/c18-9-15-19-10-16(24-15)25(22,23)14-7-12(6-13(8-14)17(20)21)11-4-2-1-3-5-11/h1-8,10H,9,18H2,(H,20,21)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description Cell Culture and TransfectionAll cell lines used in this study was purchased from American Type Culture Collection (ATCC). Mycoplasma contamination w...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469016 (US10807974, Example 32 | US10995088, Example 32 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1ccc(cc1)S(=O)(=O)CCNC(=O)c1ccccc1 Show InChI InChI=1S/C20H20N2O5S3/c21-14-16-6-11-19(28-16)30(26,27)18-9-7-17(8-10-18)29(24,25)13-12-22-20(23)15-4-2-1-3-5-15/h1-11H,12-14,21H2,(H,22,23)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM468996 (US10807974, Example 50 | US10995088, Example 50) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)C(=O)NCCO Show InChI InChI=1S/C14H16N2O4S2/c15-9-11-4-5-13(21-11)22(19,20)12-3-1-2-10(8-12)14(18)16-6-7-17/h1-5,8,17H,6-7,9,15H2,(H,16,18)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM468998 (US10807974, Example 52 | US10995088, Example 52) Show SMILES COc1ccc(cc1)S(=O)(=O)CCNC(=O)c1cccc(c1)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C21H22N2O6S3/c1-29-16-5-8-18(9-6-16)31(25,26)12-11-23-21(24)15-3-2-4-19(13-15)32(27,28)20-10-7-17(14-22)30-20/h2-10,13H,11-12,14,22H2,1H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM50526737 (CHEMBL4528500 | US10807974, Example 82 | US1099508...) Show SMILES Cc1ccc(cc1)-c1cc(ccc1S(C)(=O)=O)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C19H19NO4S3/c1-13-3-5-14(6-4-13)17-11-16(8-9-18(17)26(2,21)22)27(23,24)19-10-7-15(12-20)25-19/h3-11H,12,20H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469057 (US10807974, Example 80 | US10995088, Example 80 | ...) Show SMILES CS(=O)(=O)c1ccc(cc1-c1ccccc1)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C18H17NO4S3/c1-25(20,21)17-9-8-15(11-16(17)13-5-3-2-4-6-13)26(22,23)18-10-7-14(12-19)24-18/h2-11H,12,19H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469028 (US10807974, Example 13 | US10995088, Example 13 | ...) Show SMILES CN(C)S(=O)(=O)c1cccc(c1)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C13H16N2O4S3/c1-15(2)22(18,19)12-5-3-4-11(8-12)21(16,17)13-7-6-10(9-14)20-13/h3-8H,9,14H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469058 (US10807974, Example 81 | US10995088, Example 81 | ...) Show SMILES Cn1cc(cn1)-c1cc(ccc1S(C)(=O)=O)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C16H17N3O4S3/c1-19-10-11(9-18-19)14-7-13(4-5-15(14)25(2,20)21)26(22,23)16-6-3-12(8-17)24-16/h3-7,9-10H,8,17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM50501885 (CHEMBL4441173 | US10807974, Example 68 | US1099508...) Show SMILES CS(=O)(=O)c1cc(cc(c1)S(=O)(=O)c1ccc(CN)s1)-c1ccccc1 Show InChI InChI=1S/C18H17NO4S3/c1-25(20,21)16-9-14(13-5-3-2-4-6-13)10-17(11-16)26(22,23)18-8-7-15(12-19)24-18/h2-11H,12,19H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469015 (US10807974, Example 31 | US10995088, Example 31 | ...) Show SMILES CC(=O)NCCS(=O)(=O)c1ccc(cc1)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C15H18N2O5S3/c1-11(18)17-8-9-24(19,20)13-3-5-14(6-4-13)25(21,22)15-7-2-12(10-16)23-15/h2-7H,8-10,16H2,1H3,(H,17,18)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469061 (US10807974, Example 84 | US10995088, Example 84 | ...) Show SMILES CS(=O)(=O)c1ccc(cc1-c1ccc(F)cc1)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C18H16FNO4S3/c1-26(21,22)17-8-7-15(10-16(17)12-2-4-13(19)5-3-12)27(23,24)18-9-6-14(11-20)25-18/h2-10H,11,20H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469030 (US10807974, Example 15 | US10995088, Example 15 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1ccc(cc1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C15H18N2O4S3/c16-11-12-3-8-15(22-12)23(18,19)13-4-6-14(7-5-13)24(20,21)17-9-1-2-10-17/h3-8H,1-2,9-11,16H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM50526748 (CHEMBL4443558 | US10807974, Example 90 | US1099508...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C15H13NO2S2/c16-10-13-6-8-15(19-13)20(17,18)14-7-5-11-3-1-2-4-12(11)9-14/h1-9H,10,16H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM18353 ((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...) Show SMILES CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO Show InChI InChI=1S/C7H15NO4/c1-8-2-5(10)7(12)6(11)4(8)3-9/h4-7,9-12H,2-3H2,1H3/t4-,5+,6-,7-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	4.5	37
Hokuriku University					Assay Description Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...				Bioorg Med Chem 14: 7736-44 (2006) Article DOI: 10.1016/j.bmc.2006.08.003 BindingDB Entry DOI: 10.7270/Q2BZ649B
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM18351 ((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...) Show SMILES OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	4.5	37
Hokuriku University					Assay Description Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...				Bioorg Med Chem 14: 7736-44 (2006) Article DOI: 10.1016/j.bmc.2006.08.003 BindingDB Entry DOI: 10.7270/Q2BZ649B
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM18366 ((2R,3R,5S,6R)-2,6-bis(hydroxymethyl)piperidine-3,4...) Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)C(O)[C@@H]1O Show InChI InChI=1S/C7H15NO5/c9-1-3-5(11)7(13)6(12)4(2-10)8-3/h3-13H,1-2H2/t3-,4-,5-,6+,7?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	4.5	37
Hokuriku University					Assay Description Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...				Bioorg Med Chem 14: 7736-44 (2006) Article DOI: 10.1016/j.bmc.2006.08.003 BindingDB Entry DOI: 10.7270/Q2BZ649B
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469034 (US10807974, Example 45 | US10995088, Example 45 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCC[C@H]1COC(=O)Nc1ccc(F)cc1 |r| Show InChI InChI=1S/C23H24FN3O6S3/c24-16-6-8-17(9-7-16)26-23(28)33-15-18-3-2-12-27(18)36(31,32)21-5-1-4-20(13-21)35(29,30)22-11-10-19(14-25)34-22/h1,4-11,13,18H,2-3,12,14-15,25H2,(H,26,28)/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM43362 (MLS000069752 | N,N-dimethylcarbamodithioic acid (d...) Show SMILES CN(C)C(=S)SSC(=S)N(C)C Show InChI InChI=1S/C6H12N2S4/c1-7(2)5(9)11-12-6(10)8(3)4/h1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hungarian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human LOX expressed in HEK293 cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additi...				Bioorg Med Chem Lett 28: 3113-3118 (2018) Article DOI: 10.1016/j.bmcl.2018.07.001 BindingDB Entry DOI: 10.7270/Q28P6366
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469064 (US10807974, Example 53 | US10995088, Example 53 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccs1 Show InChI InChI=1S/C9H9NO2S3/c10-6-7-3-4-9(14-7)15(11,12)8-2-1-5-13-8/h1-5H,6,10H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469017 (US10807974, Example 33 | US10995088, Example 33 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1ccc(cc1)S(=O)(=O)CCN1CCNCC1 Show InChI InChI=1S/C17H23N3O4S3/c18-13-14-1-6-17(25-14)27(23,24)16-4-2-15(3-5-16)26(21,22)12-11-20-9-7-19-8-10-20/h1-6,19H,7-13,18H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469038 (US10807974, Example 47 | US10995088, Example 47 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cc(cc(c1)S(=O)(=O)N1CCCC1)C(F)(F)F Show InChI InChI=1S/C16H17F3N2O4S3/c17-16(18,19)11-7-13(27(22,23)15-4-3-12(10-20)26-15)9-14(8-11)28(24,25)21-5-1-2-6-21/h3-4,7-9H,1-2,5-6,10,20H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM50501883 (CHEMBL4564517 | US10807974, Example 76 | US1099508...) Show SMILES Cc1ccc(cc1)-c1cc(cc(c1)S(=O)(=O)c1ccc(CN)s1)S(C)(=O)=O Show InChI InChI=1S/C19H19NO4S3/c1-13-3-5-14(6-4-13)15-9-17(26(2,21)22)11-18(10-15)27(23,24)19-8-7-16(12-20)25-19/h3-11H,12,20H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469021 (US10807974, Example 37 | US10995088, Example 37 | ...) Show SMILES CCNC(=O)N1CCCN(CCS(=O)(=O)c2ccc(cc2)S(=O)(=O)c2ccc(CN)s2)CC1 Show InChI InChI=1S/C21H30N4O5S3/c1-2-23-21(26)25-11-3-10-24(12-13-25)14-15-32(27,28)18-5-7-19(8-6-18)33(29,30)20-9-4-17(16-22)31-20/h4-9H,2-3,10-16,22H2,1H3,(H,23,26)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469033 (US10807974, Example 44 | US10995088, Example 44 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCC[C@H]1COc1ccc(F)cc1 |r| Show InChI InChI=1S/C22H23FN2O5S3/c23-16-6-8-18(9-7-16)30-15-17-3-2-12-25(17)33(28,29)21-5-1-4-20(13-21)32(26,27)22-11-10-19(14-24)31-22/h1,4-11,13,17H,2-3,12,14-15,24H2/t17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM50505638 (CHEMBL4457578) Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O Show InChI InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-12-16(22(27)28)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9-	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd Curated by ChEMBL					Assay Description Inhibition of LOX in human IMR90 cells using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured...				J Med Chem 62: 9874-9889 (2019) Article DOI: 10.1021/acs.jmedchem.9b01283 BindingDB Entry DOI: 10.7270/Q2VM4GJ2
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469012 (US10807974, Example 28 | US10995088, Example 28 | ...) Show SMILES COCCS(=O)(=O)c1ccc(cc1)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C14H17NO5S3/c1-20-8-9-22(16,17)12-3-5-13(6-4-12)23(18,19)14-7-2-11(10-15)21-14/h2-7H,8-10,15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469029 (US10807974, Example 14 | US10807974, Example 42 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C15H18N2O4S3/c16-11-12-6-7-15(22-12)23(18,19)13-4-3-5-14(10-13)24(20,21)17-8-1-2-9-17/h3-7,10H,1-2,8-9,11,16H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM50526733 (CHEMBL4457629 | US10807974, Example 87 | US1099508...) Show SMILES NCc1ncc(s1)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C14H12N2O2S2/c15-8-13-16-9-14(19-13)20(17,18)12-6-5-10-3-1-2-4-11(10)7-12/h1-7,9H,8,15H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469051 (US10807974, Example 74 | US10995088, Example 74 | ...) Show SMILES CS(=O)(=O)c1cc(cc(c1)S(=O)(=O)c1ccc(CN)s1)-c1cccnc1 Show InChI InChI=1S/C17H16N2O4S3/c1-25(20,21)15-7-13(12-3-2-6-19-11-12)8-16(9-15)26(22,23)17-5-4-14(10-18)24-17/h2-9,11H,10,18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM469062 (US10807974, Example 85 | US10995088, Example 85 | ...) Show SMILES Cc1cccc(c1)-c1cc(ccc1S(C)(=O)=O)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C19H19NO4S3/c1-13-4-3-5-14(10-13)17-11-16(7-8-18(17)26(2,21)22)27(23,24)19-9-6-15(12-20)25-19/h3-11H,12,20H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair

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