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Compile Data Set for Download or QSAR

Found 52 hits of ic50 data for polymerid = 50001170   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50246599
PNG
(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
Show SMILES CC(C)[C@@H](N(CC(=O)NCCc1ccc(cc1)S(N)(=O)=O)S(=O)(=O)c1ccc(Oc2ccccc2)cc1)C(=O)NO |r|
Show InChI InChI=1S/C27H32N4O8S2/c1-19(2)26(27(33)30-34)31(18-25(32)29-17-16-20-8-12-23(13-9-20)40(28,35)36)41(37,38)24-14-10-22(11-15-24)39-21-6-4-3-5-7-21/h3-15,19,26,34H,16-18H2,1-2H3,(H,29,32)(H,30,33)(H2,28,35,36)/t26-/m1/s1
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n/an/a 0.310n/an/an/an/an/an/a



Instituto Superior Técnico

Curated by ChEMBL


Assay Description
Inhibition of MMP16

J Med Chem 51: 7968-79 (2008)


Article DOI: 10.1021/jm800964f
BindingDB Entry DOI: 10.7270/Q2XK8FDN
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50241252
PNG
(2-[hydroxycarbamoylmethyl-(4-phenoxy-benzenesulfon...)
Show SMILES NS(=O)(=O)c1ccc(CCNC(=O)CN(CC(=O)NO)S(=O)(=O)c2ccc(Oc3ccccc3)cc2)cc1
Show InChI InChI=1S/C24H26N4O8S2/c25-37(32,33)21-10-6-18(7-11-21)14-15-26-23(29)16-28(17-24(30)27-31)38(34,35)22-12-8-20(9-13-22)36-19-4-2-1-3-5-19/h1-13,31H,14-17H2,(H,26,29)(H,27,30)(H2,25,32,33)
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n/an/a 1n/an/an/an/an/an/a



Instituto Superior Técnico

Curated by ChEMBL


Assay Description
Inhibition of MMP16

J Med Chem 51: 7968-79 (2008)


Article DOI: 10.1021/jm800964f
BindingDB Entry DOI: 10.7270/Q2XK8FDN
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50273426
PNG
(CHEMBL515980 | N-(4-Phenoxybenzenesulfonyl)-N-hydr...)
Show SMILES CC(C)[C@@H](N(CC(O)=O)S(=O)(=O)c1ccc(Oc2ccccc2)cc1)C(=O)NO |r|
Show InChI InChI=1S/C19H22N2O7S/c1-13(2)18(19(24)20-25)21(12-17(22)23)29(26,27)16-10-8-15(9-11-16)28-14-6-4-3-5-7-14/h3-11,13,18,25H,12H2,1-2H3,(H,20,24)(H,22,23)/t18-/m1/s1
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n/an/a 1.60n/an/an/an/an/an/a



Instituto Superior Técnico

Curated by ChEMBL


Assay Description
Inhibition of MMP16

J Med Chem 51: 7968-79 (2008)


Article DOI: 10.1021/jm800964f
BindingDB Entry DOI: 10.7270/Q2XK8FDN
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50066658
PNG
((R)-N-(1-(hydroxyamino)-2-methylpropyl)-4-methoxy-...)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO
Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1
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n/an/a 6.80n/an/an/an/an/an/a



Instituto Superior Técnico

Curated by ChEMBL


Assay Description
Inhibition of MMP16

J Med Chem 51: 7968-79 (2008)


Article DOI: 10.1021/jm800964f
BindingDB Entry DOI: 10.7270/Q2XK8FDN
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50062351
PNG
((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Show SMILES CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO |r|
Show InChI InChI=1S/C20H28N4O4/c1-12(2)8-13(10-18(25)24-28)19(26)23-17(20(27)21-3)9-14-11-22-16-7-5-4-6-15(14)16/h4-7,11-13,17,22,28H,8-10H2,1-3H3,(H,21,27)(H,23,26)(H,24,25)/t13-,17+/m1/s1
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n/an/a 8n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against MMP16

J Med Chem 49: 456-8 (2006)


Article DOI: 10.1021/jm051101g
BindingDB Entry DOI: 10.7270/Q2WQ03C3
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50062351
PNG
((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Show SMILES CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO |r|
Show InChI InChI=1S/C20H28N4O4/c1-12(2)8-13(10-18(25)24-28)19(26)23-17(20(27)21-3)9-14-11-22-16-7-5-4-6-15(14)16/h4-7,11-13,17,22,28H,8-10H2,1-3H3,(H,21,27)(H,23,26)(H,24,25)/t13-,17+/m1/s1
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n/an/a 8n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloproteinase-16 (MMP-16)

Bioorg Med Chem Lett 14: 47-50 (2003)


BindingDB Entry DOI: 10.7270/Q22J6B79
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50246601
PNG
(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-phenoxyphenyl...)
Show SMILES ONC(=O)CN(CC(O)=O)S(=O)(=O)c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C16H16N2O7S/c19-15(17-22)10-18(11-16(20)21)26(23,24)14-8-6-13(7-9-14)25-12-4-2-1-3-5-12/h1-9,22H,10-11H2,(H,17,19)(H,20,21)
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n/an/a 11n/an/an/an/an/an/a



Instituto Superior Técnico

Curated by ChEMBL


Assay Description
Inhibition of MMP16

J Med Chem 51: 7968-79 (2008)


Article DOI: 10.1021/jm800964f
BindingDB Entry DOI: 10.7270/Q2XK8FDN
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50137276
PNG
(6-Hydroxy-7-methoxy-2-(4-methoxy-benzenesulfonyl)-...)
Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCc2cc(O)c(OC)cc2C1C(=O)NO
Show InChI InChI=1S/C18H20N2O7S/c1-26-12-3-5-13(6-4-12)28(24,25)20-8-7-11-9-15(21)16(27-2)10-14(11)17(20)18(22)19-23/h3-6,9-10,17,21,23H,7-8H2,1-2H3,(H,19,22)
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n/an/a 16n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloproteinase-16 (MMP-16)

Bioorg Med Chem Lett 14: 47-50 (2003)


BindingDB Entry DOI: 10.7270/Q22J6B79
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50137282
PNG
(6-Hydroxy-2-(toluene-4-sulfonyl)-1,2,3,4-tetrahydr...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCc2cc(O)ccc2C1C(=O)NO
Show InChI InChI=1S/C17H18N2O5S/c1-11-2-5-14(6-3-11)25(23,24)19-9-8-12-10-13(20)4-7-15(12)16(19)17(21)18-22/h2-7,10,16,20,22H,8-9H2,1H3,(H,18,21)
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n/an/a 21n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloproteinase-16 (MMP-16)

Bioorg Med Chem Lett 14: 47-50 (2003)


BindingDB Entry DOI: 10.7270/Q22J6B79
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50137283
PNG
(6-(benzyloxy)-N-hydroxy-2-(4-methoxyphenylsulfonyl...)
Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCc2cc(OCc3ccccc3)ccc2C1C(=O)NO
Show InChI InChI=1S/C24H24N2O6S/c1-31-19-7-10-21(11-8-19)33(29,30)26-14-13-18-15-20(32-16-17-5-3-2-4-6-17)9-12-22(18)23(26)24(27)25-28/h2-12,15,23,28H,13-14,16H2,1H3,(H,25,27)
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n/an/a 22n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloproteinase-16 (MMP-16)

Bioorg Med Chem Lett 14: 47-50 (2003)


BindingDB Entry DOI: 10.7270/Q22J6B79
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50299051
PNG
(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)
Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)c2ccccc2CC(=O)NO)cc1
Show InChI InChI=1S/C21H19NO6S/c1-27-16-6-8-17(9-7-16)28-18-10-12-19(13-11-18)29(25,26)20-5-3-2-4-15(20)14-21(23)22-24/h2-13,24H,14H2,1H3,(H,22,23)
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n/an/a 32n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry

J Med Chem 52: 6347-61 (2009)


Article DOI: 10.1021/jm900335a
BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50137287
PNG
(2-Benzenesulfonyl-6-benzyloxy-1,2,3,4-tetrahydro-i...)
Show SMILES ONC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C23H22N2O5S/c26-23(24-27)22-21-12-11-19(30-16-17-7-3-1-4-8-17)15-18(21)13-14-25(22)31(28,29)20-9-5-2-6-10-20/h1-12,15,22,27H,13-14,16H2,(H,24,26)
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n/an/a 35n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloproteinase-16 (MMP-16)

Bioorg Med Chem Lett 14: 47-50 (2003)


BindingDB Entry DOI: 10.7270/Q22J6B79
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50361601
PNG
(CHEMBL1939846)
Show SMILES CC(C)[C@H]1N(CC(=O)N(O)C1=O)S(=O)(=O)c1ccc(Oc2ccccc2)cc1 |r|
Show InChI InChI=1S/C19H20N2O6S/c1-13(2)18-19(23)21(24)17(22)12-20(18)28(25,26)16-10-8-15(9-11-16)27-14-6-4-3-5-7-14/h3-11,13,18,24H,12H2,1-2H3/t18-/m1/s1
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n/an/a 39n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP16 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs f...

J Med Chem 54: 8289-98 (2011)


Article DOI: 10.1021/jm200593b
BindingDB Entry DOI: 10.7270/Q2MP53QN
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50137281
PNG
(2-Benzenesulfonyl-6-hydroxy-7-methoxy-1,2,3,4-tetr...)
Show SMILES COc1cc2C(N(CCc2cc1O)S(=O)(=O)c1ccccc1)C(=O)NO
Show InChI InChI=1S/C17H18N2O6S/c1-25-15-10-13-11(9-14(15)20)7-8-19(16(13)17(21)18-22)26(23,24)12-5-3-2-4-6-12/h2-6,9-10,16,20,22H,7-8H2,1H3,(H,18,21)
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n/an/a 40n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloproteinase-16 (MMP-16)

Bioorg Med Chem Lett 14: 47-50 (2003)


BindingDB Entry DOI: 10.7270/Q22J6B79
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50241251
PNG
(2-[hydroxycarbamoylmethyl-(4-methoxy-benzenesulfon...)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)CC(=O)NCCc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C19H24N4O8S2/c1-31-15-4-8-17(9-5-15)33(29,30)23(13-19(25)22-26)12-18(24)21-11-10-14-2-6-16(7-3-14)32(20,27)28/h2-9,26H,10-13H2,1H3,(H,21,24)(H,22,25)(H2,20,27,28)
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n/an/a 44n/an/an/an/an/an/a



Instituto Superior Técnico

Curated by ChEMBL


Assay Description
Inhibition of MMP16

J Med Chem 51: 7968-79 (2008)


Article DOI: 10.1021/jm800964f
BindingDB Entry DOI: 10.7270/Q2XK8FDN
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50161330
PNG
((R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-h...)
Show SMILES CC(C)ON([C@H](C(C)C)C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C20H26N2O5S/c1-14(2)19(20(23)21-24)22(27-15(3)4)28(25,26)18-12-10-17(11-13-18)16-8-6-5-7-9-16/h5-15,19,24H,1-4H3,(H,21,23)/t19-/m1/s1
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n/an/a 51n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry

J Med Chem 52: 6347-61 (2009)


Article DOI: 10.1021/jm900335a
BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50294132
PNG
(CHEMBL561963 | N-hydroxy-2-(N-isopropoxy-4'-isopro...)
Show SMILES CC(C)ON(C(C(C)C)C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccc(cc1)C(C)C
Show InChI InChI=1S/C23H32N2O5S/c1-15(2)18-7-9-19(10-8-18)20-11-13-21(14-12-20)31(28,29)25(30-17(5)6)22(16(3)4)23(26)24-27/h7-17,22,27H,1-6H3,(H,24,26)
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n/an/a 51n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP16

J Med Chem 52: 4757-73 (2009)


Article DOI: 10.1021/jm900261f
BindingDB Entry DOI: 10.7270/Q2JW8DXN
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50137285
PNG
(6-(benzyloxy)-N-hydroxy-2-tosyl-1,2,3,4-tetrahydro...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCc2cc(OCc3ccccc3)ccc2C1C(=O)NO
Show InChI InChI=1S/C24H24N2O5S/c1-17-7-10-21(11-8-17)32(29,30)26-14-13-19-15-20(31-16-18-5-3-2-4-6-18)9-12-22(19)23(26)24(27)25-28/h2-12,15,23,28H,13-14,16H2,1H3,(H,25,27)
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n/an/a 56n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloproteinase-16 (MMP-16)

Bioorg Med Chem Lett 14: 47-50 (2003)


BindingDB Entry DOI: 10.7270/Q22J6B79
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50299053
PNG
(CHEMBL573714 | N-Hydroxy-2-(2-(4-methoxyphenylsulf...)
Show SMILES COc1ccc(cc1)S(=O)(=O)c1ccccc1CC(=O)NO
Show InChI InChI=1S/C15H15NO5S/c1-21-12-6-8-13(9-7-12)22(19,20)14-5-3-2-4-11(14)10-15(17)16-18/h2-9,18H,10H2,1H3,(H,16,17)
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n/an/a 130n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry

J Med Chem 52: 6347-61 (2009)


Article DOI: 10.1021/jm900335a
BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50299052
PNG
(CHEMBL584365 | N-Hydroxy-2-[2-(4'-methoxy-biphenyl...)
Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1CC(=O)NO
Show InChI InChI=1S/C21H19NO5S/c1-27-18-10-6-15(7-11-18)16-8-12-19(13-9-16)28(25,26)20-5-3-2-4-17(20)14-21(23)22-24/h2-13,24H,14H2,1H3,(H,22,23)
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n/an/a 130n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry

J Med Chem 52: 6347-61 (2009)


Article DOI: 10.1021/jm900335a
BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50299056
PNG
((+/-)-N-Hydroxy-2-[2-(4'-methoxy-biphenyl-4-sulfon...)
Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1C(C)C(=O)NO
Show InChI InChI=1S/C22H21NO5S/c1-15(22(24)23-25)20-5-3-4-6-21(20)29(26,27)19-13-9-17(10-14-19)16-7-11-18(28-2)12-8-16/h3-15,25H,1-2H3,(H,23,24)
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n/an/a 150n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry

J Med Chem 52: 6347-61 (2009)


Article DOI: 10.1021/jm900335a
BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50137279
PNG
(6-Hydroxy-2-(4-nitro-benzenesulfonyl)-1,2,3,4-tetr...)
Show SMILES ONC(=O)C1N(CCc2cc(O)ccc12)S(=O)(=O)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C16H15N3O7S/c20-12-3-6-14-10(9-12)7-8-18(15(14)16(21)17-22)27(25,26)13-4-1-11(2-5-13)19(23)24/h1-6,9,15,20,22H,7-8H2,(H,17,21)
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n/an/a 177n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloproteinase-16 (MMP-16)

Bioorg Med Chem Lett 14: 47-50 (2003)


BindingDB Entry DOI: 10.7270/Q22J6B79
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50137284
PNG
(2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-iso...)
Show SMILES ONC(=O)C1N(CCc2cc(O)ccc12)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C16H16N2O5S/c19-12-6-7-14-11(10-12)8-9-18(15(14)16(20)17-21)24(22,23)13-4-2-1-3-5-13/h1-7,10,15,19,21H,8-9H2,(H,17,20)
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n/an/a 184n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloproteinase-16 (MMP-16)

Bioorg Med Chem Lett 14: 47-50 (2003)


BindingDB Entry DOI: 10.7270/Q22J6B79
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50241253
PNG
(2-[(biphenyl-4-sulfonyl)-hydroxycarbamoylmethyl-am...)
Show SMILES NS(=O)(=O)c1ccc(CCNC(=O)CN(CC(=O)NO)S(=O)(=O)c2ccc(cc2)-c2ccccc2)cc1
Show InChI InChI=1S/C24H26N4O7S2/c25-36(32,33)21-10-6-18(7-11-21)14-15-26-23(29)16-28(17-24(30)27-31)37(34,35)22-12-8-20(9-13-22)19-4-2-1-3-5-19/h1-13,31H,14-17H2,(H,26,29)(H,27,30)(H2,25,32,33)
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n/an/a 186n/an/an/an/an/an/a



Instituto Superior Técnico

Curated by ChEMBL


Assay Description
Inhibition of MMP16

J Med Chem 51: 7968-79 (2008)


Article DOI: 10.1021/jm800964f
BindingDB Entry DOI: 10.7270/Q2XK8FDN
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50137277
PNG
(2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetr...)
Show SMILES Nc1ccc(cc1)S(=O)(=O)N1CCc2cc(O)ccc2C1C(=O)NO
Show InChI InChI=1S/C16H17N3O5S/c17-11-1-4-13(5-2-11)25(23,24)19-8-7-10-9-12(20)3-6-14(10)15(19)16(21)18-22/h1-6,9,15,20,22H,7-8,17H2,(H,18,21)
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n/an/a 202n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloproteinase-16 (MMP-16)

Bioorg Med Chem Lett 14: 47-50 (2003)


BindingDB Entry DOI: 10.7270/Q22J6B79
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50299054
PNG
(2-[2-(Biphenyl-4-sulfonyl)phenyl]N-hydroxy-acetami...)
Show SMILES ONC(=O)Cc1ccccc1S(=O)(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C20H17NO4S/c22-20(21-23)14-17-8-4-5-9-19(17)26(24,25)18-12-10-16(11-13-18)15-6-2-1-3-7-15/h1-13,23H,14H2,(H,21,22)
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n/an/a 220n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry

J Med Chem 52: 6347-61 (2009)


Article DOI: 10.1021/jm900335a
BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50299058
PNG
((+/-)-2-[2-(Biphenyl-4-sulfonyl)phenyl]N-hydroxy-p...)
Show SMILES CC(C(=O)NO)c1ccccc1S(=O)(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C21H19NO4S/c1-15(21(23)22-24)19-9-5-6-10-20(19)27(25,26)18-13-11-17(12-14-18)16-7-3-2-4-8-16/h2-15,24H,1H3,(H,22,23)
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n/an/a 470n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry

J Med Chem 52: 6347-61 (2009)


Article DOI: 10.1021/jm900335a
BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50299055
PNG
(CHEMBL573936 | [2-(4'-Methoxy-biphenyl-4-sulfonyl)...)
Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1CC(O)=O
Show InChI InChI=1S/C21H18O5S/c1-26-18-10-6-15(7-11-18)16-8-12-19(13-9-16)27(24,25)20-5-3-2-4-17(20)14-21(22)23/h2-13H,14H2,1H3,(H,22,23)
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n/an/a 730n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry

J Med Chem 52: 6347-61 (2009)


Article DOI: 10.1021/jm900335a
BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50161331
PNG
(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)
Show SMILES CC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C17H20N2O5S/c1-13(2)24-19(12-17(20)18-21)25(22,23)16-10-8-15(9-11-16)14-6-4-3-5-7-14/h3-11,13,21H,12H2,1-2H3,(H,18,20)
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n/an/a 900n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP16

J Med Chem 52: 4757-73 (2009)


Article DOI: 10.1021/jm900261f
BindingDB Entry DOI: 10.7270/Q2JW8DXN
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50246600
PNG
(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(O)=O)CC(=O)NO
Show InChI InChI=1S/C11H14N2O7S/c1-20-8-2-4-9(5-3-8)21(18,19)13(7-11(15)16)6-10(14)12-17/h2-5,17H,6-7H2,1H3,(H,12,14)(H,15,16)
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n/an/a 996n/an/an/an/an/an/a



Instituto Superior Técnico

Curated by ChEMBL


Assay Description
Inhibition of MMP16

J Med Chem 51: 7968-79 (2008)


Article DOI: 10.1021/jm800964f
BindingDB Entry DOI: 10.7270/Q2XK8FDN
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50299060
PNG
((+/-)-2-[2-(4'-Methoxy-biphenyl-4-sulfonyl)phenyl]...)
Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1C(C)C(O)=O
Show InChI InChI=1S/C22H20O5S/c1-15(22(23)24)20-5-3-4-6-21(20)28(25,26)19-13-9-17(10-14-19)16-7-11-18(27-2)12-8-16/h3-15H,1-2H3,(H,23,24)
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n/an/a 1.10E+3n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry

J Med Chem 52: 6347-61 (2009)


Article DOI: 10.1021/jm900335a
BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50361599
PNG
(CHEMBL1939844)
Show SMILES COc1ccc(cc1)S(=O)(=O)N1CC(=O)N(O)C(=O)[C@H]1C(C)C |r|
Show InChI InChI=1S/C14H18N2O6S/c1-9(2)13-14(18)16(19)12(17)8-15(13)23(20,21)11-6-4-10(22-3)5-7-11/h4-7,9,13,19H,8H2,1-3H3/t13-/m1/s1
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n/an/a 1.10E+3n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP16 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs f...

J Med Chem 54: 8289-98 (2011)


Article DOI: 10.1021/jm200593b
BindingDB Entry DOI: 10.7270/Q2MP53QN
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50299059
PNG
(CHEMBL573934 | N-Hydroxy-2-(4'-methoxybiphenyl-4-y...)
Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1C(=O)NO
Show InChI InChI=1S/C20H17NO5S/c1-26-16-10-6-14(7-11-16)15-8-12-17(13-9-15)27(24,25)19-5-3-2-4-18(19)20(22)21-23/h2-13,23H,1H3,(H,21,22)
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n/an/a 1.20E+3n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry

J Med Chem 52: 6347-61 (2009)


Article DOI: 10.1021/jm900335a
BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50299065
PNG
(CHEMBL575896 | N-Hydroxy-2-(4-phenoxy-benzenesulfo...)
Show SMILES ONC(=O)c1ccccc1S(=O)(=O)c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C19H15NO5S/c21-19(20-22)17-8-4-5-9-18(17)26(23,24)16-12-10-15(11-13-16)25-14-6-2-1-3-7-14/h1-13,22H,(H,20,21)
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n/an/a 1.30E+3n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry

J Med Chem 52: 6347-61 (2009)


Article DOI: 10.1021/jm900335a
BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50137286
PNG
(6-Hydroxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-te...)
Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCc2cc(O)ccc2C1C(=O)NO
Show InChI InChI=1S/C17H18N2O6S/c1-25-13-3-5-14(6-4-13)26(23,24)19-9-8-11-10-12(20)2-7-15(11)16(19)17(21)18-22/h2-7,10,16,20,22H,8-9H2,1H3,(H,18,21)
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n/an/a 1.68E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloproteinase-16 (MMP-16)

Bioorg Med Chem Lett 14: 47-50 (2003)


BindingDB Entry DOI: 10.7270/Q22J6B79
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50137278
PNG
(2-(2,5-Dichloro-benzenesulfonyl)-6-hydroxy-1,2,3,4...)
Show SMILES ONC(=O)C1N(CCc2cc(O)ccc12)S(=O)(=O)c1cc(Cl)ccc1Cl
Show InChI InChI=1S/C16H14Cl2N2O5S/c17-10-1-4-13(18)14(8-10)26(24,25)20-6-5-9-7-11(21)2-3-12(9)15(20)16(22)19-23/h1-4,7-8,15,21,23H,5-6H2,(H,19,22)
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n/an/a 1.84E+3n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01855
BindingDB Entry DOI: 10.7270/Q2GB281X
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50137278
PNG
(2-(2,5-Dichloro-benzenesulfonyl)-6-hydroxy-1,2,3,4...)
Show SMILES ONC(=O)C1N(CCc2cc(O)ccc12)S(=O)(=O)c1cc(Cl)ccc1Cl
Show InChI InChI=1S/C16H14Cl2N2O5S/c17-10-1-4-13(18)14(8-10)26(24,25)20-6-5-9-7-11(21)2-3-12(9)15(20)16(22)19-23/h1-4,7-8,15,21,23H,5-6H2,(H,19,22)
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n/an/a 1.84E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloproteinase-16 (MMP-16)

Bioorg Med Chem Lett 14: 47-50 (2003)


BindingDB Entry DOI: 10.7270/Q22J6B79
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50361600
PNG
(CHEMBL1939845)
Show SMILES CC(C)[C@H]1N(CC(=O)N(O)C1=O)S(=O)(=O)c1ccc(cc1)-c1ccccc1 |r|
Show InChI InChI=1S/C19H20N2O5S/c1-13(2)18-19(23)21(24)17(22)12-20(18)27(25,26)16-10-8-15(9-11-16)14-6-4-3-5-7-14/h3-11,13,18,24H,12H2,1-2H3/t18-/m1/s1
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n/an/a 2.20E+3n/an/an/an/an/an/a



Instituto Superior T£cnico

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP16 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs f...

J Med Chem 54: 8289-98 (2011)


Article DOI: 10.1021/jm200593b
BindingDB Entry DOI: 10.7270/Q2MP53QN
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50299061
PNG
(CHEMBL573935 | [2-(Biphenyl-4-sulfonyl)phenyl]acet...)
Show SMILES OC(=O)Cc1ccccc1S(=O)(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C20H16O4S/c21-20(22)14-17-8-4-5-9-19(17)25(23,24)18-12-10-16(11-13-18)15-6-2-1-3-7-15/h1-13H,14H2,(H,21,22)
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n/an/a 4.30E+3n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry

J Med Chem 52: 6347-61 (2009)


Article DOI: 10.1021/jm900335a
BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50137280
PNG
(6-Benzyloxy-2-(2,5-dichloro-benzenesulfonyl)-1,2,3...)
Show SMILES ONC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)S(=O)(=O)c1cc(Cl)ccc1Cl
Show InChI InChI=1S/C23H20Cl2N2O5S/c24-17-6-9-20(25)21(13-17)33(30,31)27-11-10-16-12-18(32-14-15-4-2-1-3-5-15)7-8-19(16)22(27)23(28)26-29/h1-9,12-13,22,29H,10-11,14H2,(H,26,28)
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n/an/a 4.63E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloproteinase-16 (MMP-16)

Bioorg Med Chem Lett 14: 47-50 (2003)


BindingDB Entry DOI: 10.7270/Q22J6B79
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50294131
PNG
((R)-2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl...)
Show SMILES CC(C)ON([C@H](C(C)C)C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccc(OCc2ccc(Cl)cc2)cc1 |r|
Show InChI InChI=1S/C27H31ClN2O6S/c1-18(2)26(27(31)29-32)30(36-19(3)4)37(33,34)25-15-9-22(10-16-25)21-7-13-24(14-8-21)35-17-20-5-11-23(28)12-6-20/h5-16,18-19,26,32H,17H2,1-4H3,(H,29,31)/t26-/m1/s1
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n/an/a 5.00E+3n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP16

J Med Chem 52: 4757-73 (2009)


Article DOI: 10.1021/jm900261f
BindingDB Entry DOI: 10.7270/Q2JW8DXN
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50299064
PNG
(2-(Biphenyl-4-ylsulfonyl)N-hydroxybenzamide | CHEM...)
Show SMILES ONC(=O)c1ccccc1S(=O)(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C19H15NO4S/c21-19(20-22)17-8-4-5-9-18(17)25(23,24)16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13,22H,(H,20,21)
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n/an/a 5.10E+3n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry

J Med Chem 52: 6347-61 (2009)


Article DOI: 10.1021/jm900335a
BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50299063
PNG
(CHEMBL584122 | N-Hydroxy-2-[4-(4-methoxy-phenoxy)b...)
Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)c2ccccc2C(=O)NO)cc1
Show InChI InChI=1S/C20H17NO6S/c1-26-14-6-8-15(9-7-14)27-16-10-12-17(13-11-16)28(24,25)19-5-3-2-4-18(19)20(22)21-23/h2-13,23H,1H3,(H,21,22)
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n/an/a 6.00E+3n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry

J Med Chem 52: 6347-61 (2009)


Article DOI: 10.1021/jm900335a
BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50299067
PNG
((+/-)-2-[2-(Biphenyl-4-sulfonyl)phenyl]propionic A...)
Show SMILES CC(C(O)=O)c1ccccc1S(=O)(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C21H18O4S/c1-15(21(22)23)19-9-5-6-10-20(19)26(24,25)18-13-11-17(12-14-18)16-7-3-2-4-8-16/h2-15H,1H3,(H,22,23)
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n/an/a 6.30E+3n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry

J Med Chem 52: 6347-61 (2009)


Article DOI: 10.1021/jm900335a
BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50299062
PNG
(CHEMBL579067 | {2-[4-(4-Methoxy-phenoxy)benzenesul...)
Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)c2ccccc2CC(O)=O)cc1
Show InChI InChI=1S/C21H18O6S/c1-26-16-6-8-17(9-7-16)27-18-10-12-19(13-11-18)28(24,25)20-5-3-2-4-15(20)14-21(22)23/h2-13H,14H2,1H3,(H,22,23)
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n/an/a 6.50E+3n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry

J Med Chem 52: 6347-61 (2009)


Article DOI: 10.1021/jm900335a
BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50063917
PNG
((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)
Show SMILES CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C |r|
Show InChI InChI=1S/C15H29N3O5/c1-8(2)7-9(10(19)13(21)18-23)12(20)17-11(14(22)16-6)15(3,4)5/h8-11,19,23H,7H2,1-6H3,(H,16,22)(H,17,20)(H,18,21)/t9-,10+,11-/m1/s1
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n/an/a 1.00E+4n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of MMP16 (unknown origin) catalytic domain using MCA-Arg-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-Glu-Arg-NH2 as substrate preincubated for 60 mins fol...

J Med Chem 59: 313-27 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01434
BindingDB Entry DOI: 10.7270/Q20G3N0F
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50294124
PNG
(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Show SMILES CC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccc(OCc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C24H25ClN2O6S/c1-17(2)33-27(15-24(28)26-29)34(30,31)23-13-7-20(8-14-23)19-5-11-22(12-6-19)32-16-18-3-9-21(25)10-4-18/h3-14,17,29H,15-16H2,1-2H3,(H,26,28)
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n/an/a 1.50E+4n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP16

J Med Chem 52: 4757-73 (2009)


Article DOI: 10.1021/jm900261f
BindingDB Entry DOI: 10.7270/Q2JW8DXN
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50299057
PNG
((R)-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-met...)
Show SMILES CC(C)ON([C@H](C(C)C)C(O)=O)S(=O)(=O)c1ccc(cc1)-c1ccccc1 |r|
Show InChI InChI=1S/C20H25NO5S/c1-14(2)19(20(22)23)21(26-15(3)4)27(24,25)18-12-10-17(11-13-18)16-8-6-5-7-9-16/h5-15,19H,1-4H3,(H,22,23)/t19-/m1/s1
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n/an/a 1.80E+4n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry

J Med Chem 52: 6347-61 (2009)


Article DOI: 10.1021/jm900335a
BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50299068
PNG
(CHEMBL575895 | N-Hydroxy-2-(4-methoxy-benzenesulfo...)
Show SMILES COc1ccc(cc1)S(=O)(=O)c1ccccc1C(=O)NO
Show InChI InChI=1S/C14H13NO5S/c1-20-10-6-8-11(9-7-10)21(18,19)13-5-3-2-4-12(13)14(16)15-17/h2-9,17H,1H3,(H,15,16)
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n/an/a 3.10E+4n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry

J Med Chem 52: 6347-61 (2009)


Article DOI: 10.1021/jm900335a
BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
More data for this
Ligand-Target Pair
Matrix metalloproteinase-16


(Homo sapiens (Human))		BDBM50180601
PNG
(3-(4-(2-phenylethynyl)benzoyl)pentanoic acid | CHE...)
Show SMILES CCC(CC(O)=O)C(=O)c1ccc(cc1)C#Cc1ccccc1
Show InChI InChI=1S/C20H18O3/c1-2-17(14-19(21)22)20(23)18-12-10-16(11-13-18)9-8-15-6-4-3-5-7-15/h3-7,10-13,17H,2,14H2,1H3,(H,21,22)
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n/an/a 3.20E+4n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against MMP16

J Med Chem 49: 456-8 (2006)


Article DOI: 10.1021/jm051101g
BindingDB Entry DOI: 10.7270/Q2WQ03C3
More data for this
Ligand-Target Pair
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