Compile Data Set for Download or QSAR

Found 31 hits of ic50 data for polymerid = 50002723   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...) Show SMILES CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO |r| Show InChI InChI=1S/C20H28N4O4/c1-12(2)8-13(10-18(25)24-28)19(26)23-17(20(27)21-3)9-14-11-22-16-7-5-4-6-15(14)16/h4-7,11-13,17,22,28H,8-10H2,1-3H3,(H,21,27)(H,23,26)(H,24,25)/t13-,17+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP17 catalytic domain				J Biol Chem 282: 27781-91 (2007) Article DOI: 10.1074/jbc.M703286200 BindingDB Entry DOI: 10.7270/Q2Z89C58
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50035507 (CHEMBL3355722) Show SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C23H37N5O5/c1-15(2)12-17(14-20(29)28-33)22(31)27-19(13-16-8-4-3-5-9-16)23(32)26-18(21(25)30)10-6-7-11-24/h3-5,8-9,15,17-19,33H,6-7,10-14,24H2,1-2H3,(H2,25,30)(H,26,32)(H,27,31)(H,28,29)/t17-,18+,19+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
University Medical Center Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant ADAM17 using Mca-PLAQAV-Dpa-RSSSR-NH2				Bioorg Med Chem 23: 192-202 (2014) Article DOI: 10.1016/j.bmc.2014.11.013 BindingDB Entry DOI: 10.7270/Q26Q1ZVW
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50035475 (CHEMBL3355723) Show SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCNC(=O)c1ccc(F)cc1)C(N)=O |r| Show InChI InChI=1S/C30H40FN5O6/c1-19(2)16-22(18-26(37)36-42)29(40)35-25(17-20-8-4-3-5-9-20)30(41)34-24(27(32)38)10-6-7-15-33-28(39)21-11-13-23(31)14-12-21/h3-5,8-9,11-14,19,22,24-25,42H,6-7,10,15-18H2,1-2H3,(H2,32,38)(H,33,39)(H,34,41)(H,35,40)(H,36,37)/t22-,24+,25+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
University Medical Center Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant ADAM17 using Mca-PLAQAV-Dpa-RSSSR-NH2				Bioorg Med Chem 23: 192-202 (2014) Article DOI: 10.1016/j.bmc.2014.11.013 BindingDB Entry DOI: 10.7270/Q26Q1ZVW
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50146471 (CHEMBL431226 | N-{1-(1,4-Dioxa-spiro[4.5]dec-8-yl)...) Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(C2CCC3(CC2)OCCO3)N(O)C=O)c2ccccc2n1 Show InChI InChI=1S/C28H32N2O7S/c1-20-16-22(25-4-2-3-5-26(25)29-20)17-35-23-6-8-24(9-7-23)38(33,34)18-27(30(32)19-31)21-10-12-28(13-11-21)36-14-15-37-28/h2-9,16,19,21,27,32H,10-15,17-18H2,1H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-17				Bioorg Med Chem Lett 14: 2897-900 (2004) Article DOI: 10.1016/j.bmcl.2004.03.048 BindingDB Entry DOI: 10.7270/Q27S7N7C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50146480 (CHEMBL329967 | N-Hydroxy-N-{1-(4-hydroxyimino-cycl...) Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(CC2CCC(CC2)N=O)N(O)C=O)c2ccccc2n1 |(-1.77,-1.66,;-3.1,-.89,;-3.1,.67,;-4.43,1.42,;-4.45,2.96,;-3.12,3.73,;-1.79,2.98,;-1.79,1.44,;-.44,.68,;.89,1.46,;.87,3,;-.46,3.77,;2.22,.69,;2.99,2.03,;1.47,-.64,;3.55,-.08,;4.91,.65,;4.9,2.19,;6.21,3,;6.17,4.53,;7.47,5.34,;8.83,4.62,;8.89,3.08,;7.57,2.26,;10.13,5.44,;11.5,4.71,;6.21,-.15,;7.57,.58,;6.17,-1.69,;7.47,-2.5,;-5.76,.65,;-7.11,1.42,;-8.44,.65,;-8.44,-.89,;-7.09,-1.66,;-5.76,-.89,;-4.43,-1.66,)| Show InChI InChI=1S/C27H31N3O6S/c1-19-14-21(26-4-2-3-5-27(26)28-19)16-36-24-10-12-25(13-11-24)37(34,35)17-23(30(33)18-31)15-20-6-8-22(29-32)9-7-20/h2-5,10-14,18,20,22-23,33H,6-9,15-17H2,1H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-17				Bioorg Med Chem Lett 14: 2897-900 (2004) Article DOI: 10.1016/j.bmcl.2004.03.048 BindingDB Entry DOI: 10.7270/Q27S7N7C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50146467 (CHEMBL99365 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...) Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(CC2CCC(=O)CC2)N(O)C=O)c2ccccc2n1 Show InChI InChI=1S/C27H30N2O6S/c1-19-14-21(26-4-2-3-5-27(26)28-19)16-35-24-10-12-25(13-11-24)36(33,34)17-22(29(32)18-30)15-20-6-8-23(31)9-7-20/h2-5,10-14,18,20,22,32H,6-9,15-17H2,1H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-17				Bioorg Med Chem Lett 14: 2897-900 (2004) Article DOI: 10.1016/j.bmcl.2004.03.048 BindingDB Entry DOI: 10.7270/Q27S7N7C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50146478 (CHEMBL98390 | N-Hydroxy-N-{1-(1-isobutyl-piperidin...) Show SMILES CC(C)CN1CCC(CC(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)N(O)C=O)CC1 Show InChI InChI=1S/C30H39N3O5S/c1-22(2)18-32-14-12-24(13-15-32)17-26(33(35)21-34)20-39(36,37)28-10-8-27(9-11-28)38-19-25-16-23(3)31-30-7-5-4-6-29(25)30/h4-11,16,21-22,24,26,35H,12-15,17-20H2,1-3H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-17				Bioorg Med Chem Lett 14: 2897-900 (2004) Article DOI: 10.1016/j.bmcl.2004.03.048 BindingDB Entry DOI: 10.7270/Q27S7N7C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50146479 (CHEMBL328645 | N-Hydroxy-N-{1-(4-hydroxyimino-cycl...) Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(C2CCC(CC2)N=O)N(O)C=O)c2ccccc2n1 |(6.8,-4.04,;5.46,-3.27,;5.44,-1.73,;4.11,-.96,;4.09,.58,;5.44,1.35,;6.77,.6,;6.77,-.94,;8.1,-1.71,;9.43,-.93,;9.43,.62,;8.08,1.37,;10.78,-1.69,;11.55,-.36,;10.02,-3.03,;12.11,-2.46,;13.44,-1.69,;13.42,-.16,;12.07,.6,;12.05,2.14,;13.38,2.93,;14.73,2.17,;14.75,.62,;13.37,4.47,;12.02,5.23,;14.78,-2.43,;16.11,-1.64,;14.82,-3.97,;16.15,-4.72,;2.78,-1.73,;1.45,-.96,;.12,-1.75,;.12,-3.29,;1.45,-4.06,;2.78,-3.27,;4.13,-4.04,)| Show InChI InChI=1S/C26H29N3O6S/c1-18-14-20(24-4-2-3-5-25(24)27-18)15-35-22-10-12-23(13-11-22)36(33,34)16-26(29(32)17-30)19-6-8-21(28-31)9-7-19/h2-5,10-14,17,19,21,26,32H,6-9,15-16H2,1H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-17				Bioorg Med Chem Lett 14: 2897-900 (2004) Article DOI: 10.1016/j.bmcl.2004.03.048 BindingDB Entry DOI: 10.7270/Q27S7N7C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50146473 (2,2-Dimethyl-propionic acid 4-{2-(formyl-hydroxy-a...) Show SMILES [#6]-c1cc(-[#6]-[#8]-c2ccc(cc2)S(=O)(=O)[#6]-[#6](\[#6]=[#6]-2\[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#8]-[#6](=O)C([#6])([#6])[#6])-[#7](-[#8])-[#6]=O)c2ccccc2n1 Show InChI InChI=1S/C31H37N3O7S/c1-22-17-24(28-7-5-6-8-29(28)32-22)19-40-26-9-11-27(12-10-26)42(38,39)20-25(34(37)21-35)18-23-13-15-33(16-14-23)41-30(36)31(2,3)4/h5-12,17-18,21,25,37H,13-16,19-20H2,1-4H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-17				Bioorg Med Chem Lett 14: 2897-900 (2004) Article DOI: 10.1016/j.bmcl.2004.03.048 BindingDB Entry DOI: 10.7270/Q27S7N7C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50146469 (CHEMBL319782 | N-Hydroxy-N-[2-[4-(2-methyl-quinoli...) Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(C2CCC(=O)CC2)N(O)C=O)c2ccccc2n1 Show InChI InChI=1S/C26H28N2O6S/c1-18-14-20(24-4-2-3-5-25(24)27-18)15-34-22-10-12-23(13-11-22)35(32,33)16-26(28(31)17-29)19-6-8-21(30)9-7-19/h2-5,10-14,17,19,26,31H,6-9,15-16H2,1H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-17				Bioorg Med Chem Lett 14: 2897-900 (2004) Article DOI: 10.1016/j.bmcl.2004.03.048 BindingDB Entry DOI: 10.7270/Q27S7N7C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50146474 (CHEMBL419896 | N-{2-(1,4-Dioxa-spiro[4.5]dec-8-yl)...) Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(CC2CCC3(CC2)OCCO3)N(O)C=O)c2ccccc2n1 Show InChI InChI=1S/C29H34N2O7S/c1-21-16-23(27-4-2-3-5-28(27)30-21)18-36-25-6-8-26(9-7-25)39(34,35)19-24(31(33)20-32)17-22-10-12-29(13-11-22)37-14-15-38-29/h2-9,16,20,22,24,33H,10-15,17-19H2,1H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-17				Bioorg Med Chem Lett 14: 2897-900 (2004) Article DOI: 10.1016/j.bmcl.2004.03.048 BindingDB Entry DOI: 10.7270/Q27S7N7C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50146470 (CHEMBL328199 | N-Hydroxy-N-{1-(4-methylene-cyclohe...) Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(C2CCC(=C)CC2)N(O)C=O)c2ccccc2n1 Show InChI InChI=1S/C27H30N2O5S/c1-19-7-9-21(10-8-19)27(29(31)18-30)17-35(32,33)24-13-11-23(12-14-24)34-16-22-15-20(2)28-26-6-4-3-5-25(22)26/h3-6,11-15,18,21,27,31H,1,7-10,16-17H2,2H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-17				Bioorg Med Chem Lett 14: 2897-900 (2004) Article DOI: 10.1016/j.bmcl.2004.03.048 BindingDB Entry DOI: 10.7270/Q27S7N7C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50146468 (CHEMBL98852 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...) Show SMILES [#6]-c1cc(-[#6]-[#8]-c2ccc(cc2)S(=O)(=O)[#6]-[#6](\[#6]=[#6]-2/[#6]-[#6]-[#6](=O)-[#6]-[#6]-2)-[#7](-[#8])-[#6]=O)c2ccccc2n1 Show InChI InChI=1S/C27H28N2O6S/c1-19-14-21(26-4-2-3-5-27(26)28-19)16-35-24-10-12-25(13-11-24)36(33,34)17-22(29(32)18-30)15-20-6-8-23(31)9-7-20/h2-5,10-15,18,22,32H,6-9,16-17H2,1H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-17				Bioorg Med Chem Lett 14: 2897-900 (2004) Article DOI: 10.1016/j.bmcl.2004.03.048 BindingDB Entry DOI: 10.7270/Q27S7N7C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50146477 (CHEMBL99045 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...) Show SMILES [#6]-c1cc(-[#6]-[#8]-c2ccc(cc2)S(=O)(=O)[#6]-[#6](\[#6]=[#6]-2\[#6]-[#6]-[#8]-[#6]-[#6]-2)-[#7](-[#8])-[#6]=O)c2ccccc2n1 Show InChI InChI=1S/C26H28N2O6S/c1-19-14-21(25-4-2-3-5-26(25)27-19)16-34-23-6-8-24(9-7-23)35(31,32)17-22(28(30)18-29)15-20-10-12-33-13-11-20/h2-9,14-15,18,22,30H,10-13,16-17H2,1H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-17				Bioorg Med Chem Lett 14: 2897-900 (2004) Article DOI: 10.1016/j.bmcl.2004.03.048 BindingDB Entry DOI: 10.7270/Q27S7N7C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50146476 (CHEMBL99995 | N-Hydroxy-N-{1-(4-hydroxyimino-cyclo...) Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(C=C2CCC(CC2)N=O)N(O)C=O)c2ccccc2n1 |(15.21,-2.83,;13.88,-2.06,;13.87,-.52,;12.54,.23,;12.53,1.77,;13.84,2.56,;15.19,1.79,;15.19,.26,;16.53,-.5,;17.86,.27,;17.85,1.82,;16.5,2.58,;19.19,-.49,;18.44,-1.83,;19.96,.86,;20.52,-1.26,;21.87,-.52,;21.87,1,;23.18,1.81,;24.55,1.09,;25.86,1.91,;25.81,3.45,;24.44,4.17,;23.13,3.35,;27.11,4.26,;28.47,3.54,;23.19,-1.34,;24.55,-.59,;23.15,-2.87,;24.45,-3.69,;11.21,-.54,;9.87,.23,;8.55,-.54,;8.54,-2.08,;9.88,-2.85,;11.21,-2.08,;12.54,-2.85,)| Show InChI InChI=1S/C27H29N3O6S/c1-19-14-21(26-4-2-3-5-27(26)28-19)16-36-24-10-12-25(13-11-24)37(34,35)17-23(30(33)18-31)15-20-6-8-22(29-32)9-7-20/h2-5,10-15,18,22-23,33H,6-9,16-17H2,1H3/b20-15-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-17				Bioorg Med Chem Lett 14: 2897-900 (2004) Article DOI: 10.1016/j.bmcl.2004.03.048 BindingDB Entry DOI: 10.7270/Q27S7N7C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50035472 (CHEMBL3355724) Show SMILES CC(C)C[C@H](CC(=O)NOC(=O)c1ccc(F)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCNC(=O)c1ccc(F)cc1)C(N)=O |r| Show InChI InChI=1S/C37H43F2N5O7/c1-23(2)20-27(22-32(45)44-51-37(50)26-13-17-29(39)18-14-26)35(48)43-31(21-24-8-4-3-5-9-24)36(49)42-30(33(40)46)10-6-7-19-41-34(47)25-11-15-28(38)16-12-25/h3-5,8-9,11-18,23,27,30-31H,6-7,10,19-22H2,1-2H3,(H2,40,46)(H,41,47)(H,42,49)(H,43,48)(H,44,45)/t27-,30+,31+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
University Medical Center Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant ADAM17 using Mca-PLAQAV-Dpa-RSSSR-NH2				Bioorg Med Chem 23: 192-202 (2014) Article DOI: 10.1016/j.bmc.2014.11.013 BindingDB Entry DOI: 10.7270/Q26Q1ZVW
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50146472 (CHEMBL318252 | N-Hydroxy-N-{1-(1-isobutyl-piperidi...) Show SMILES [#6]-[#6](-[#6])-[#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]/[#6](-[#6]S(=O)(=O)c1ccc(-[#8]-[#6]-c2cc(-[#6])nc3ccccc23)cc1)-[#7](-[#8])-[#6]=O Show InChI InChI=1S/C30H37N3O5S/c1-22(2)18-32-14-12-24(13-15-32)17-26(33(35)21-34)20-39(36,37)28-10-8-27(9-11-28)38-19-25-16-23(3)31-30-7-5-4-6-29(25)30/h4-11,16-17,21-22,26,35H,12-15,18-20H2,1-3H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-17				Bioorg Med Chem Lett 14: 2897-900 (2004) Article DOI: 10.1016/j.bmcl.2004.03.048 BindingDB Entry DOI: 10.7270/Q27S7N7C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50146475 (CHEMBL98202 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...) Show SMILES [#6]-c1cc(-[#6]-[#8]-c2ccc(cc2)S(=O)(=O)[#6]-[#6](\[#6]=[#6]-2\[#6]-[#6]-[#16]-[#6]-[#6]-2)-[#7](-[#8])-[#6]=O)c2ccccc2n1 Show InChI InChI=1S/C26H28N2O5S2/c1-19-14-21(25-4-2-3-5-26(25)27-19)16-33-23-6-8-24(9-7-23)35(31,32)17-22(28(30)18-29)15-20-10-12-34-13-11-20/h2-9,14-15,18,22,30H,10-13,16-17H2,1H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-17				Bioorg Med Chem Lett 14: 2897-900 (2004) Article DOI: 10.1016/j.bmcl.2004.03.048 BindingDB Entry DOI: 10.7270/Q27S7N7C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM400682 (US10000476, Compound I-41) Show SMILES Cc1cccn(CC2(NC(=O)NC2=O)c2ccc(Cc3ccc(F)cc3)cc2)c1=O Show InChI InChI=1S/C23H20FN3O3/c1-15-3-2-12-27(20(15)28)14-23(21(29)25-22(30)26-23)18-8-4-16(5-9-18)13-17-6-10-19(24)11-7-17/h2-12H,13-14H2,1H3,(H2,25,26,29,30)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universite degli Studi di Firenze					Assay Description MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...				Bioorg Med Chem 17: 4503-9 (2009) BindingDB Entry DOI: 10.7270/Q2V69MXD
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM400650 (US10000476, Compound I-9) Show SMILES Cc1cccn(CC2(NC(=O)NC2=O)c2ccc(Oc3ccccc3)cc2)c1=O Show InChI InChI=1S/C22H19N3O4/c1-15-6-5-13-25(19(15)26)14-22(20(27)23-21(28)24-22)16-9-11-18(12-10-16)29-17-7-3-2-4-8-17/h2-13H,14H2,1H3,(H2,23,24,27,28)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universite degli Studi di Firenze					Assay Description MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...				Bioorg Med Chem 17: 4503-9 (2009) BindingDB Entry DOI: 10.7270/Q2V69MXD
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM400727 (US10000476, Compound I-86) Show SMILES Cc1cccn(CC2(NC(=O)NC2=O)c2ccc(Oc3ccccc3F)cc2)c1=O Show InChI InChI=1S/C22H18FN3O4/c1-14-5-4-12-26(19(14)27)13-22(20(28)24-21(29)25-22)15-8-10-16(11-9-15)30-18-7-3-2-6-17(18)23/h2-12H,13H2,1H3,(H2,24,25,28,29)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universite degli Studi di Firenze					Assay Description MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...				Bioorg Med Chem 17: 4503-9 (2009) BindingDB Entry DOI: 10.7270/Q2V69MXD
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50265079 ((4-[1-methyl-2,4-dioxo-6-(3-phenyl-prop-1-ynyl)-1,...) Show SMILES Cn1c2ccc(cc2c(=O)n(Cc2ccc(cc2)C(O)=O)c1=O)C#CCc1ccccc1 Show InChI InChI=1S/C26H20N2O4/c1-27-23-15-12-19(9-5-8-18-6-3-2-4-7-18)16-22(23)24(29)28(26(27)32)17-20-10-13-21(14-11-20)25(30)31/h2-4,6-7,10-16H,8,17H2,1H3,(H,30,31)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP17 catalytic domain				J Biol Chem 282: 27781-91 (2007) Article DOI: 10.1074/jbc.M703286200 BindingDB Entry DOI: 10.7270/Q2Z89C58
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50234334 (BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIA...) Show SMILES O=C(OCc1ccccc1)c1cn2c(cc(=O)n(Cc3ccccc3)c2=O)s1 Show InChI InChI=1S/C21H16N2O4S/c24-18-11-19-23(21(26)22(18)12-15-7-3-1-4-8-15)13-17(28-19)20(25)27-14-16-9-5-2-6-10-16/h1-11,13H,12,14H2	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad CEU San Pablo Curated by ChEMBL					Assay Description Inhibition of MMP17 (unknown origin)				J Med Chem 57: 10205-19 (2014) Article DOI: 10.1021/jm500505f BindingDB Entry DOI: 10.7270/Q2NK3GMC
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50265079 ((4-[1-methyl-2,4-dioxo-6-(3-phenyl-prop-1-ynyl)-1,...) Show SMILES Cn1c2ccc(cc2c(=O)n(Cc2ccc(cc2)C(O)=O)c1=O)C#CCc1ccccc1 Show InChI InChI=1S/C26H20N2O4/c1-27-23-15-12-19(9-5-8-18-6-3-2-4-7-18)16-22(23)24(29)28(26(27)32)17-20-10-13-21(14-11-20)25(30)31/h2-4,6-7,10-16H,8,17H2,1H3,(H,30,31)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad CEU San Pablo Curated by ChEMBL					Assay Description Inhibition of MMP17 (unknown origin)				J Med Chem 57: 10205-19 (2014) Article DOI: 10.1021/jm500505f BindingDB Entry DOI: 10.7270/Q2NK3GMC
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM400681 (US10000476, Compound I-40) Show SMILES Cc1cccn(CC2(NC(=O)NC2=O)c2ccc(Cc3ccccc3)cc2)c1=O Show InChI InChI=1S/C23H21N3O3/c1-16-6-5-13-26(20(16)27)15-23(21(28)24-22(29)25-23)19-11-9-18(10-12-19)14-17-7-3-2-4-8-17/h2-13H,14-15H2,1H3,(H2,24,25,28,29)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universite degli Studi di Firenze					Assay Description MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...				Bioorg Med Chem 17: 4503-9 (2009) BindingDB Entry DOI: 10.7270/Q2V69MXD
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM400703 (US10000476, Compound I-62) Show SMILES Cc1cccn(CC2(NC(=O)NC2=O)c2cccc(c2)-c2cccnc2)c1=O Show InChI InChI=1S/C21H18N4O3/c1-14-5-4-10-25(18(14)26)13-21(19(27)23-20(28)24-21)17-8-2-6-15(11-17)16-7-3-9-22-12-16/h2-12H,13H2,1H3,(H2,23,24,27,28)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universite degli Studi di Firenze					Assay Description MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...				Bioorg Med Chem 17: 4503-9 (2009) BindingDB Entry DOI: 10.7270/Q2V69MXD
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM400668 (US10000476, Compound I-27) Show SMILES COc1ccc(Cl)cc1C1(Cn2cccc(C)c2=O)NC(=O)NC1=O Show InChI InChI=1S/C17H16ClN3O4/c1-10-4-3-7-21(14(10)22)9-17(15(23)19-16(24)20-17)12-8-11(18)5-6-13(12)25-2/h3-8H,9H2,1-2H3,(H2,19,20,23,24)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universite degli Studi di Firenze					Assay Description MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...				Bioorg Med Chem 17: 4503-9 (2009) BindingDB Entry DOI: 10.7270/Q2V69MXD
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM400699 (US10000476, Compound I-58 | US10000476, Compound I...) Show SMILES Cc1cccn(CC2(NC(=O)NC2=O)c2cccc(OCc3ccccc3)c2)c1=O Show InChI InChI=1S/C23H21N3O4/c1-16-7-6-12-26(20(16)27)15-23(21(28)24-22(29)25-23)18-10-5-11-19(13-18)30-14-17-8-3-2-4-9-17/h2-13H,14-15H2,1H3,(H2,24,25,28,29)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universite degli Studi di Firenze					Assay Description MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...				Bioorg Med Chem 17: 4503-9 (2009) BindingDB Entry DOI: 10.7270/Q2V69MXD
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50234334 (BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIA...) Show SMILES O=C(OCc1ccccc1)c1cn2c(cc(=O)n(Cc3ccccc3)c2=O)s1 Show InChI InChI=1S/C21H16N2O4S/c24-18-11-19-23(21(26)22(18)12-15-7-3-1-4-8-15)13-17(28-19)20(25)27-14-16-9-5-2-6-10-16/h1-11,13H,12,14H2	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP17 catalytic domain				J Biol Chem 282: 27781-91 (2007) Article DOI: 10.1074/jbc.M703286200 BindingDB Entry DOI: 10.7270/Q2Z89C58
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM400651 (US10000476, Compound I-10 | US10000476, Compound I...) Show SMILES Cc1cccn(CC2(NC(=O)NC2=O)c2ccc(F)c(F)c2)c1=O Show InChI InChI=1S/C16H13F2N3O3/c1-9-3-2-6-21(13(9)22)8-16(14(23)19-15(24)20-16)10-4-5-11(17)12(18)7-10/h2-7H,8H2,1H3,(H2,19,20,23,24)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universite degli Studi di Firenze					Assay Description MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...				Bioorg Med Chem 17: 4503-9 (2009) BindingDB Entry DOI: 10.7270/Q2V69MXD
					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM400231 (US10000476, Compound I-1 | US10000476, Compound I-...) Show SMILES Cc1cccn(CC2(NC(=O)NC2=O)c2ccncc2)c1=O Show InChI InChI=1S/C15H14N4O3/c1-10-3-2-8-19(12(10)20)9-15(11-4-6-16-7-5-11)13(21)17-14(22)18-15/h2-8H,9H2,1H3,(H2,17,18,21,22)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universite degli Studi di Firenze					Assay Description MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...				Bioorg Med Chem 17: 4503-9 (2009) BindingDB Entry DOI: 10.7270/Q2V69MXD
					More data for this Ligand-Target Pair