Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase kinase kinase 4 (Homo sapiens (Human)) | BDBM50556597 (CHEMBL4756586) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of C-terminal NanoLuc-fused full length MAP3K4 (unknown origin) expressed in HEK293T cells after 2 hrs by NanoBRET assay | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112721 BindingDB Entry DOI: 10.7270/Q24X5CGW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 4 (Homo sapiens (Human)) | BDBM50401152 (CHEMBL2205766) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cellzome Ltd Curated by ChEMBL | Assay Description Inhibition of MAP3K4 | Bioorg Med Chem Lett 22: 4613-8 (2012) Article DOI: 10.1016/j.bmcl.2012.05.090 BindingDB Entry DOI: 10.7270/Q2HQ412B | |||||||||||
More data for this Ligand-Target Pair |