Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50176394 (CHEMBL202361 | octanoic acid (R)-2-octanoyloxy-3-t...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Activity at LPA3 receptor transfected RH7777 cells | Bioorg Med Chem Lett 16: 633-40 (2005) Article DOI: 10.1016/j.bmcl.2005.10.031 BindingDB Entry DOI: 10.7270/Q2ZC82DB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50271625 (2-(2-(2-aminoacetamido)-3-(2,4-dinitrophenylthio)p...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Memphis Curated by ChEMBL | Assay Description Antagonist activity at LPA3 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium response | Bioorg Med Chem 17: 7457-64 (2009) Article DOI: 10.1016/j.bmc.2009.09.022 BindingDB Entry DOI: 10.7270/Q2GB244M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50271625 (2-(2-(2-aminoacetamido)-3-(2,4-dinitrophenylthio)p...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Memphis Curated by ChEMBL | Assay Description Antagonist activity at LPA3 receptor (unknown origin) expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium conce... | Bioorg Med Chem 16: 6207-17 (2008) Article DOI: 10.1016/j.bmc.2008.04.035 BindingDB Entry DOI: 10.7270/Q270817C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50170847 (CHEMBL190484 | Thiophosphoric acid (E)-dodec-9-eny...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor | J Med Chem 48: 4919-30 (2005) Article DOI: 10.1021/jm049609r BindingDB Entry DOI: 10.7270/Q2HD7V5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50170860 (CHEMBL191365 | Thiophosphoric acid dodecyl ester) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor | J Med Chem 48: 4919-30 (2005) Article DOI: 10.1021/jm049609r BindingDB Entry DOI: 10.7270/Q2HD7V5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50170852 (CHEMBL187402 | Thiophosphoric acid (E)-tetradec-9-...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor | J Med Chem 48: 4919-30 (2005) Article DOI: 10.1021/jm049609r BindingDB Entry DOI: 10.7270/Q2HD7V5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50271701 (2,6-bis(3-carboxyacrylamido)benzoic acid | 4,4'-(2...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Memphis Curated by ChEMBL | Assay Description Antagonist activity at LPA3 receptor (unknown origin) expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium conce... | Bioorg Med Chem 16: 6207-17 (2008) Article DOI: 10.1016/j.bmc.2008.04.035 BindingDB Entry DOI: 10.7270/Q270817C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50271701 (2,6-bis(3-carboxyacrylamido)benzoic acid | 4,4'-(2...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Memphis Curated by ChEMBL | Assay Description Antagonist activity at LPA3 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium response | Bioorg Med Chem 17: 7457-64 (2009) Article DOI: 10.1016/j.bmc.2009.09.022 BindingDB Entry DOI: 10.7270/Q2GB244M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50170858 (CHEMBL190349 | Phosphoric acid mono-((E)-dodec-9-e...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor | J Med Chem 48: 4919-30 (2005) Article DOI: 10.1021/jm049609r BindingDB Entry DOI: 10.7270/Q2HD7V5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50146240 (CHEMBL91058 | Phosphoric acid mono-[(R)-3-[4-(3-me...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description In vitro antagonism of LPA-evoked [35S]-GTP-gammaS binding to lysophosphatidic acid receptor 3 in HEK293T cell lines | Bioorg Med Chem Lett 14: 2735-40 (2004) Article DOI: 10.1016/j.bmcl.2004.03.076 BindingDB Entry DOI: 10.7270/Q2DF6QN9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50373831 (CHEMBL272087) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Antagonist activity at LPA3 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assay | Bioorg Med Chem Lett 18: 1037-41 (2008) Article DOI: 10.1016/j.bmcl.2007.12.024 BindingDB Entry DOI: 10.7270/Q2JQ11W8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM557823 (1-[4-[6-[5-[[6-(3,3-difluorocyclobutoxy)pyrazin-2-...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 49.6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo... | Citation and Details BindingDB Entry DOI: 10.7270/Q26M3B1D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50398090 (CHEMBL2182050 | US9321738, 13) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Curated by ChEMBL | Assay Description Antagonist activity at human recombinant LPA3 expressed in chem-1 cells assessed as inhibition of LPA-induced intracellular calcium mobilization incu... | J Med Chem 55: 7920-39 (2012) Article DOI: 10.1021/jm301022v BindingDB Entry DOI: 10.7270/Q26974Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50398090 (CHEMBL2182050 | US9321738, 13) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 65.7 | n/a | n/a | n/a | n/a | n/a | 25 |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description Test compounds were prepared by adding 90 μL of HBSS/20 mM HEPES/0.1% BSA buffer to 2 μL of serially diluted compounds. To prepare serial dilut... | US Patent US9321738 (2016) BindingDB Entry DOI: 10.7270/Q2B56HKJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50176391 (CHEMBL202185 | octanoic acid (R)-2-octanoyloxy-3-p...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Activity at LPA3 receptor transfected RH7777 cells | Bioorg Med Chem Lett 16: 633-40 (2005) Article DOI: 10.1016/j.bmcl.2005.10.031 BindingDB Entry DOI: 10.7270/Q2ZC82DB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50170843 (CHEMBL190430 | Phosphoric acid mono-((E)-tetradec-...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor | J Med Chem 48: 4919-30 (2005) Article DOI: 10.1021/jm049609r BindingDB Entry DOI: 10.7270/Q2HD7V5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50170851 (CHEMBL188591 | Phosphoric acid mono-((E)-tetradec-...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 103 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor | J Med Chem 48: 4919-30 (2005) Article DOI: 10.1021/jm049609r BindingDB Entry DOI: 10.7270/Q2HD7V5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50170857 (CHEMBL187795 | Thiophosphoric acid decyl ester) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 122 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor | J Med Chem 48: 4919-30 (2005) Article DOI: 10.1021/jm049609r BindingDB Entry DOI: 10.7270/Q2HD7V5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50398093 (CHEMBL2182046 | US9321738, 6) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 132 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Curated by ChEMBL | Assay Description Antagonist activity at human recombinant LPA3 expressed in chem-1 cells assessed as inhibition of LPA-induced intracellular calcium mobilization incu... | J Med Chem 55: 7920-39 (2012) Article DOI: 10.1021/jm301022v BindingDB Entry DOI: 10.7270/Q26974Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50398093 (CHEMBL2182046 | US9321738, 6) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 132 | n/a | n/a | n/a | n/a | n/a | 25 |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description Test compounds were prepared by adding 90 μL of HBSS/20 mM HEPES/0.1% BSA buffer to 2 μL of serially diluted compounds. To prepare serial dilut... | US Patent US9321738 (2016) BindingDB Entry DOI: 10.7270/Q2B56HKJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Rattus norvegicus) | BDBM50177339 (CHEMBL436763 | potassium ((2R,4R)-2-(heptadec-9-en...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 136 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Activity at LPA3 receptor in RH7777 rat hepatoma cell line | Bioorg Med Chem Lett 16: 451-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.096 BindingDB Entry DOI: 10.7270/Q2Z89C01 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50176397 (CHEMBL203986 | nonanoic acid (S)-2-nonanoyloxy-3-p...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 143 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Activity at LPA3 receptor transfected RH7777 cells | Bioorg Med Chem Lett 16: 633-40 (2005) Article DOI: 10.1016/j.bmcl.2005.10.031 BindingDB Entry DOI: 10.7270/Q2ZC82DB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50271805 ((2R)-3-(phosphonooxy)propane-1,2-diyl diheptanoate...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 143 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Memphis Curated by ChEMBL | Assay Description Inhibition of LPA3 receptor (unknown origin) | Bioorg Med Chem 16: 6207-17 (2008) Article DOI: 10.1016/j.bmc.2008.04.035 BindingDB Entry DOI: 10.7270/Q270817C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50170849 (CHEMBL189296 | Thiophosphoric acid tetradecyl este...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 162 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor | J Med Chem 48: 4919-30 (2005) Article DOI: 10.1021/jm049609r BindingDB Entry DOI: 10.7270/Q2HD7V5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50146232 (CHEMBL440696 | Phosphoric acid mono-{(R)-2-((Z)-oc...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 175 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description In vitro antagonism of LPA-evoked [35S]-GTP-gammaS binding to lysophosphatidic acid receptor 3 in HEK293T cell lines | Bioorg Med Chem Lett 14: 2735-40 (2004) Article DOI: 10.1016/j.bmcl.2004.03.076 BindingDB Entry DOI: 10.7270/Q2DF6QN9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50271806 (CHEMBL482506 | Heptanoic acid (R)-1-heptanoyloxyme...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 184 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Memphis Curated by ChEMBL | Assay Description Inhibition of LPA3 receptor (unknown origin) | Bioorg Med Chem 16: 6207-17 (2008) Article DOI: 10.1016/j.bmc.2008.04.035 BindingDB Entry DOI: 10.7270/Q270817C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50176398 ((S)-O-2,3-bis(octyloxy)propyl O,O-dihydrogen phosp...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 184 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Activity at LPA3 receptor transfected RH7777 cells | Bioorg Med Chem Lett 16: 633-40 (2005) Article DOI: 10.1016/j.bmcl.2005.10.031 BindingDB Entry DOI: 10.7270/Q2ZC82DB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50176398 ((S)-O-2,3-bis(octyloxy)propyl O,O-dihydrogen phosp...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 184 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Activity at LPA3 receptor transfected RH7777 cells | Bioorg Med Chem Lett 16: 633-40 (2005) Article DOI: 10.1016/j.bmcl.2005.10.031 BindingDB Entry DOI: 10.7270/Q2ZC82DB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50176393 (CHEMBL383095 | octanoic acid (S)-2-octanoyloxy-3-p...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 207 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Activity at LPA3 receptor transfected RH7777 cells | Bioorg Med Chem Lett 16: 633-40 (2005) Article DOI: 10.1016/j.bmcl.2005.10.031 BindingDB Entry DOI: 10.7270/Q2ZC82DB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Rattus norvegicus) | BDBM50177337 (CHEMBL370846 | potassium ((2S,4S)-2-(heptadec-9-en...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 209 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Activity at LPA3 receptor in RH7777 rat hepatoma cell line | Bioorg Med Chem Lett 16: 451-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.096 BindingDB Entry DOI: 10.7270/Q2Z89C01 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Rattus norvegicus) | BDBM50177337 (CHEMBL370846 | potassium ((2S,4S)-2-(heptadec-9-en...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 209 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Activity at LPA3 receptor in RH7777 rat hepatoma cell line | Bioorg Med Chem Lett 16: 451-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.096 BindingDB Entry DOI: 10.7270/Q2Z89C01 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50176389 (CHEMBL440396 | thiophosphoric acid (S)-2-octanoyla...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 251 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Activity at LPA3 receptor transfected RH7777 cells | Bioorg Med Chem Lett 16: 633-40 (2005) Article DOI: 10.1016/j.bmcl.2005.10.031 BindingDB Entry DOI: 10.7270/Q2ZC82DB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50176389 (CHEMBL440396 | thiophosphoric acid (S)-2-octanoyla...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 251 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Activity at LPA3 receptor transfected RH7777 cells | Bioorg Med Chem Lett 16: 633-40 (2005) Article DOI: 10.1016/j.bmcl.2005.10.031 BindingDB Entry DOI: 10.7270/Q2ZC82DB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM223530 (US9321738, 4) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 279 | n/a | n/a | n/a | n/a | n/a | 25 |
HOFFMAN-LA ROCHE INC. US Patent | Assay Description Test compounds were prepared by adding 90 μL of HBSS/20 mM HEPES/0.1% BSA buffer to 2 μL of serially diluted compounds. To prepare serial dilut... | US Patent US9321738 (2016) BindingDB Entry DOI: 10.7270/Q2B56HKJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50170859 (3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)-3-met...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 301 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor | J Med Chem 48: 4919-30 (2005) Article DOI: 10.1021/jm049609r BindingDB Entry DOI: 10.7270/Q2HD7V5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50176392 (CHEMBL379248 | thiophosphoric acid (R)-2-octanoyla...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 302 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Activity at LPA3 receptor transfected RH7777 cells | Bioorg Med Chem Lett 16: 633-40 (2005) Article DOI: 10.1016/j.bmcl.2005.10.031 BindingDB Entry DOI: 10.7270/Q2ZC82DB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM557820 (1-[4-[6-[5-[[6-(cyclobutoxy)pyrazin-2-yl]amino]-1-...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 327 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo... | Citation and Details BindingDB Entry DOI: 10.7270/Q26M3B1D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50170855 (CHEMBL363935 | Thiophosphoric acid dec-9-enyl este...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor | J Med Chem 48: 4919-30 (2005) Article DOI: 10.1021/jm049609r BindingDB Entry DOI: 10.7270/Q2HD7V5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM557838 (1-[4-[6-[5-[(6-isopropoxypyrazin-2-yl)amino]-1-met...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 341 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo... | Citation and Details BindingDB Entry DOI: 10.7270/Q26M3B1D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50241460 (4-(3-benzamidophenylamino)-4-oxobut-2-enoic acid |...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 347 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Memphis Curated by ChEMBL | Assay Description Antagonist activity at LPA3 receptor (unknown origin) expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium conce... | Bioorg Med Chem 16: 6207-17 (2008) Article DOI: 10.1016/j.bmc.2008.04.035 BindingDB Entry DOI: 10.7270/Q270817C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50146241 (CHEMBL329422 | Phosphoric acid mono-[(R)-3-[4-(3-m...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 351 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description In vitro antagonism of LPA-evoked [35S]-GTP-gammaS binding to lysophosphatidic acid receptor 3 in HEK293T cell lines | Bioorg Med Chem Lett 14: 2735-40 (2004) Article DOI: 10.1016/j.bmcl.2004.03.076 BindingDB Entry DOI: 10.7270/Q2DF6QN9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50170850 (CHEMBL361255 | Phosphoric acid monodecyl ester) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 384 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor | J Med Chem 48: 4919-30 (2005) Article DOI: 10.1021/jm049609r BindingDB Entry DOI: 10.7270/Q2HD7V5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50170854 (CHEMBL187711 | Phosphoric acid monododecyl ester) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 384 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor | J Med Chem 48: 4919-30 (2005) Article DOI: 10.1021/jm049609r BindingDB Entry DOI: 10.7270/Q2HD7V5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50176396 (CHEMBL204037 | Serine amide phospate derivative | ...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 414 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Activity at LPA3 receptor transfected RH7777 cells | Bioorg Med Chem Lett 16: 633-40 (2005) Article DOI: 10.1016/j.bmcl.2005.10.031 BindingDB Entry DOI: 10.7270/Q2ZC82DB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50170842 (CHEMBL187633 | Phosphoric acid monotetradecyl este...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 422 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor | J Med Chem 48: 4919-30 (2005) Article DOI: 10.1021/jm049609r BindingDB Entry DOI: 10.7270/Q2HD7V5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50146242 (3,4,5-Trimethoxy-benzoic acid 4-[(R)-2-((Z)-octade...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 427 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia Curated by ChEMBL | Assay Description In vitro antagonism of LPA-evoked [35S]-GTP-gammaS binding to lysophosphatidic acid receptor 3 in HEK293T cell lines | Bioorg Med Chem Lett 14: 2735-40 (2004) Article DOI: 10.1016/j.bmcl.2004.03.076 BindingDB Entry DOI: 10.7270/Q2DF6QN9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50170862 (CHEMBL191055 | Octanoic acid (S)-1-methyl-2-octano...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 454 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor | J Med Chem 48: 4919-30 (2005) Article DOI: 10.1021/jm049609r BindingDB Entry DOI: 10.7270/Q2HD7V5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM50398098 (CHEMBL2182023) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 478 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Curated by ChEMBL | Assay Description Antagonist activity at human recombinant LPA3 expressed in chem-1 cells assessed as inhibition of LPA-induced intracellular calcium mobilization incu... | J Med Chem 55: 7920-39 (2012) Article DOI: 10.1021/jm301022v BindingDB Entry DOI: 10.7270/Q26974Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Rattus norvegicus) | BDBM50177340 (CHEMBL382116 | potassium ((2R,4S)-2-(heptadec-9-en...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 484 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Activity at LPA3 receptor in RH7777 rat hepatoma cell line | Bioorg Med Chem Lett 16: 451-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.096 BindingDB Entry DOI: 10.7270/Q2Z89C01 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (Homo sapiens (Human)) | BDBM557829 (1-[4-[5-fluoro-6-[5-[(6-isopropoxypyrazin-2-yl)ami...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 495 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo... | Citation and Details BindingDB Entry DOI: 10.7270/Q26M3B1D | |||||||||||
More data for this Ligand-Target Pair |
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