Found 72 hits of ic50 data for polymerid = 50004668 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50565509
(CHEMBL4790993)Show SMILES C[C@H]1C[C@H](C)C(=O)C(C1)[C@H](O)CC1CC(=O)N(CC(=O)NC2C3CC4(C)CC2CC(C)(C3)C4)C(=O)C1 |r,wU:1.0,wD:3.3,9.10,TLB:25:24:21:28.31.29,30:29:21:23.24.26,20:21:28.31.29:23.24.26,20:21:26:28.29.32,31:29:21.22.23:26,THB:32:29:21:23.24.26,32:24:21:28.31.29,31:22:26:28.29.32,(-6.82,-3.14,;-6.82,-1.6,;-8.15,-.83,;-8.15,.71,;-9.49,1.48,;-6.82,1.49,;-6.82,3.03,;-5.49,.71,;-5.49,-.83,;-4.15,1.48,;-4.15,3.02,;-2.82,.71,;-1.49,1.48,;-1.49,3.02,;-.15,3.8,;-.15,5.34,;1.18,3.02,;2.52,3.79,;3.85,3.02,;3.85,1.48,;5.18,3.79,;6.52,3.02,;8.01,2.64,;8.8,4.01,;10.3,4.55,;11.07,5.88,;8.91,4.81,;8.18,3.53,;9.08,2.46,;10.44,2.06,;11.45,.89,;8.94,1.47,;11.21,3.37,;1.18,1.48,;2.52,.71,;-.15,.71,)| | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of Legionella pneumophila Mip assessed as reduction in PPIase activity using succinyl-Ala-Leu-Pro-Phe-4-nitroanilide as substrate incubate... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00911
BindingDB Entry DOI: 10.7270/Q22V2KW9 |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200286
(CHEMBL3890138)Show SMILES COc1cc(cc(OC)c1OC)C(=O)NC[C@H](C)OC(=O)[C@@H]1CCCCN1S(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C26H34N2O8S/c1-18(16-27-25(29)20-14-22(33-2)24(35-4)23(15-20)34-3)36-26(30)21-12-8-9-13-28(21)37(31,32)17-19-10-6-5-7-11-19/h5-7,10-11,14-15,18,21H,8-9,12-13,16-17H2,1-4H3,(H,27,29)/t18-,21-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200286
(CHEMBL3890138)Show SMILES COc1cc(cc(OC)c1OC)C(=O)NC[C@H](C)OC(=O)[C@@H]1CCCCN1S(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C26H34N2O8S/c1-18(16-27-25(29)20-14-22(33-2)24(35-4)23(15-20)34-3)36-26(30)21-12-8-9-13-28(21)37(31,32)17-19-10-6-5-7-11-19/h5-7,10-11,14-15,18,21H,8-9,12-13,16-17H2,1-4H3,(H,27,29)/t18-,21-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200320
(CHEMBL3949202)Show SMILES Clc1ccc(CS(=O)(=O)N2CCCC[C@H]2C(=O)OCCCc2cccnc2)cc1 |r| Show InChI InChI=1S/C21H25ClN2O4S/c22-19-10-8-18(9-11-19)16-29(26,27)24-13-2-1-7-20(24)21(25)28-14-4-6-17-5-3-12-23-15-17/h3,5,8-12,15,20H,1-2,4,6-7,13-14,16H2/t20-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200320
(CHEMBL3949202)Show SMILES Clc1ccc(CS(=O)(=O)N2CCCC[C@H]2C(=O)OCCCc2cccnc2)cc1 |r| Show InChI InChI=1S/C21H25ClN2O4S/c22-19-10-8-18(9-11-19)16-29(26,27)24-13-2-1-7-20(24)21(25)28-14-4-6-17-5-3-12-23-15-17/h3,5,8-12,15,20H,1-2,4,6-7,13-14,16H2/t20-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200285
(CHEMBL3930292)Show SMILES O=C(OCCOC(=O)c1cccnc1)[C@@H]1CCCCN1S(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C21H24N2O6S/c24-20(18-9-6-11-22-15-18)28-13-14-29-21(25)19-10-4-5-12-23(19)30(26,27)16-17-7-2-1-3-8-17/h1-3,6-9,11,15,19H,4-5,10,12-14,16H2/t19-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200285
(CHEMBL3930292)Show SMILES O=C(OCCOC(=O)c1cccnc1)[C@@H]1CCCCN1S(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C21H24N2O6S/c24-20(18-9-6-11-22-15-18)28-13-14-29-21(25)19-10-4-5-12-23(19)30(26,27)16-17-7-2-1-3-8-17/h1-3,6-9,11,15,19H,4-5,10,12-14,16H2/t19-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200317
(CHEMBL3950488)Show SMILES COc1cc(ccc1O)C(=O)NCCOC(=O)[C@@H]1CCCCN1S(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C23H28N2O7S/c1-31-21-15-18(10-11-20(21)26)22(27)24-12-14-32-23(28)19-9-5-6-13-25(19)33(29,30)16-17-7-3-2-4-8-17/h2-4,7-8,10-11,15,19,26H,5-6,9,12-14,16H2,1H3,(H,24,27)/t19-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200317
(CHEMBL3950488)Show SMILES COc1cc(ccc1O)C(=O)NCCOC(=O)[C@@H]1CCCCN1S(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C23H28N2O7S/c1-31-21-15-18(10-11-20(21)26)22(27)24-12-14-32-23(28)19-9-5-6-13-25(19)33(29,30)16-17-7-3-2-4-8-17/h2-4,7-8,10-11,15,19,26H,5-6,9,12-14,16H2,1H3,(H,24,27)/t19-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200298
(CHEMBL3899080)Show SMILES C[C@@H](CNC(=O)c1cccnc1)OC(=O)[C@@H]1CCCCN1S(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C22H27N3O5S/c1-17(14-24-21(26)19-10-7-12-23-15-19)30-22(27)20-11-5-6-13-25(20)31(28,29)16-18-8-3-2-4-9-18/h2-4,7-10,12,15,17,20H,5-6,11,13-14,16H2,1H3,(H,24,26)/t17-,20-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200298
(CHEMBL3899080)Show SMILES C[C@@H](CNC(=O)c1cccnc1)OC(=O)[C@@H]1CCCCN1S(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C22H27N3O5S/c1-17(14-24-21(26)19-10-7-12-23-15-19)30-22(27)20-11-5-6-13-25(20)31(28,29)16-18-8-3-2-4-9-18/h2-4,7-10,12,15,17,20H,5-6,11,13-14,16H2,1H3,(H,24,26)/t17-,20-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200331
(CHEMBL3941933)Show SMILES [O-][N+](=O)c1ccc(CS(=O)(=O)N2CCCCC2C(=O)OCCCc2cccnc2)cc1 Show InChI InChI=1S/C21H25N3O6S/c25-21(30-14-4-6-17-5-3-12-22-15-17)20-7-1-2-13-23(20)31(28,29)16-18-8-10-19(11-9-18)24(26)27/h3,5,8-12,15,20H,1-2,4,6-7,13-14,16H2 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200331
(CHEMBL3941933)Show SMILES [O-][N+](=O)c1ccc(CS(=O)(=O)N2CCCCC2C(=O)OCCCc2cccnc2)cc1 Show InChI InChI=1S/C21H25N3O6S/c25-21(30-14-4-6-17-5-3-12-22-15-17)20-7-1-2-13-23(20)31(28,29)16-18-8-10-19(11-9-18)24(26)27/h3,5,8-12,15,20H,1-2,4,6-7,13-14,16H2 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50565510
(CHEMBL4794577)Show SMILES C[C@H]1C[C@H](C)C(=O)C(C1)[C@H](O)CC1CC(=O)N(CC(=O)NC2C3CC4(C)CC(O)(C3)CC2(C)C4)C(=O)C1 |r,TLB:25:24:21:29.30.27,28:27:21:33.24.23,20:21:23:29.27.26,THB:26:27:21:33.24.23,26:24:21:29.30.27,32:31:23:29.27.26,20:21:29.30.27:33.24.23,30:31:23:29.27.26,30:27:21.31.33:23| | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of Legionella pneumophila Mip assessed as reduction in PPIase activity using succinyl-Ala-Leu-Pro-Phe-4-nitroanilide as substrate incubate... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00911
BindingDB Entry DOI: 10.7270/Q22V2KW9 |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200338
(CHEMBL3970282)Show SMILES COCCOc1cc(OCCOC)cc(c1)C(=O)NCCOC(=O)[C@@H]1CCCCN1S(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C28H38N2O9S/c1-35-14-16-37-24-18-23(19-25(20-24)38-17-15-36-2)27(31)29-11-13-39-28(32)26-10-6-7-12-30(26)40(33,34)21-22-8-4-3-5-9-22/h3-5,8-9,18-20,26H,6-7,10-17,21H2,1-2H3,(H,29,31)/t26-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50565511
(CHEMBL4788177)Show SMILES CCC12CC3CC(C1)C(NC(=O)CN1C(=O)CC(C[C@@H](O)C4C[C@@H](C)C[C@H](C)C4=O)CC1=O)C(C3)C2 |r,wU:23.24,wD:26.27,19.20,TLB:1:2:8:5.34.4,34:33:7:5.4.3,THB:3:4:8:35.2.7,3:2:8:5.34.4,9:8:5.34.4:35.2.7,9:8:7:5.4.3,34:4:8.33.35:7,(12.61,5.88,;11.07,5.88,;10.3,4.55,;11.21,3.37,;10.44,2.06,;9.08,2.46,;8.18,3.53,;8.91,4.81,;6.52,3.02,;5.18,3.79,;3.85,3.02,;3.85,1.48,;2.52,3.79,;1.18,3.02,;-.15,3.8,;-.15,5.34,;-1.49,3.02,;-1.49,1.48,;-2.82,.71,;-4.15,1.48,;-4.15,3.02,;-5.49,.71,;-5.49,-.83,;-6.82,-1.6,;-6.82,-3.14,;-8.15,-.83,;-8.15,.71,;-9.49,1.48,;-6.82,1.49,;-6.82,3.03,;-.15,.71,;1.18,1.48,;2.52,.71,;8.01,2.64,;8.94,1.47,;8.8,4.01,)| | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of Legionella pneumophila Mip assessed as reduction in PPIase activity using succinyl-Ala-Leu-Pro-Phe-4-nitroanilide as substrate incubate... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00911
BindingDB Entry DOI: 10.7270/Q22V2KW9 |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200338
(CHEMBL3970282)Show SMILES COCCOc1cc(OCCOC)cc(c1)C(=O)NCCOC(=O)[C@@H]1CCCCN1S(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C28H38N2O9S/c1-35-14-16-37-24-18-23(19-25(20-24)38-17-15-36-2)27(31)29-11-13-39-28(32)26-10-6-7-12-30(26)40(33,34)21-22-8-4-3-5-9-22/h3-5,8-9,18-20,26H,6-7,10-17,21H2,1-2H3,(H,29,31)/t26-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200297
(CHEMBL3939283)Show SMILES Fc1ccc(CS(=O)(=O)N2CCCC[C@H]2C(=O)OCCCc2cccnc2)cc1 |r| Show InChI InChI=1S/C21H25FN2O4S/c22-19-10-8-18(9-11-19)16-29(26,27)24-13-2-1-7-20(24)21(25)28-14-4-6-17-5-3-12-23-15-17/h3,5,8-12,15,20H,1-2,4,6-7,13-14,16H2/t20-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200283
(CHEMBL3924013)Show SMILES O=C(OCCCc1cccnc1)[C@@H]1CCCCN1S(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C21H26N2O4S/c24-21(27-15-7-11-18-10-6-13-22-16-18)20-12-4-5-14-23(20)28(25,26)17-19-8-2-1-3-9-19/h1-3,6,8-10,13,16,20H,4-5,7,11-12,14-15,17H2/t20-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200297
(CHEMBL3939283)Show SMILES Fc1ccc(CS(=O)(=O)N2CCCC[C@H]2C(=O)OCCCc2cccnc2)cc1 |r| Show InChI InChI=1S/C21H25FN2O4S/c22-19-10-8-18(9-11-19)16-29(26,27)24-13-2-1-7-20(24)21(25)28-14-4-6-17-5-3-12-23-15-17/h3,5,8-12,15,20H,1-2,4,6-7,13-14,16H2/t20-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200283
(CHEMBL3924013)Show SMILES O=C(OCCCc1cccnc1)[C@@H]1CCCCN1S(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C21H26N2O4S/c24-21(27-15-7-11-18-10-6-13-22-16-18)20-12-4-5-14-23(20)28(25,26)17-19-8-2-1-3-9-19/h1-3,6,8-10,13,16,20H,4-5,7,11-12,14-15,17H2/t20-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50335225
((S)-1-Phenylmethanesulfonyl-piperidine-2-carboxyli...)Show SMILES COc1cc(CCCOC(=O)[C@@H]2CCCCN2S(=O)(=O)Cc2ccccc2)cc(OC)c1OC Show InChI InChI=1S/C25H33NO7S/c1-30-22-16-20(17-23(31-2)24(22)32-3)12-9-15-33-25(27)21-13-7-8-14-26(21)34(28,29)18-19-10-5-4-6-11-19/h4-6,10-11,16-17,21H,7-9,12-15,18H2,1-3H3/t21-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wu£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of PPIase activity of Legionella pneumophila MIP protein expressed in Escherichia coli by spectrophotometry |
J Med Chem 54: 277-83 (2011)
Article DOI: 10.1021/jm101156y
BindingDB Entry DOI: 10.7270/Q2GF0VG2 |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200316
(CHEMBL3970581)Show SMILES Clc1cccc(CS(=O)(=O)N2CCCC[C@H]2C(=O)OCCCc2cccnc2)c1 |r| Show InChI InChI=1S/C21H25ClN2O4S/c22-19-9-3-6-18(14-19)16-29(26,27)24-12-2-1-10-20(24)21(25)28-13-5-8-17-7-4-11-23-15-17/h3-4,6-7,9,11,14-15,20H,1-2,5,8,10,12-13,16H2/t20-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200316
(CHEMBL3970581)Show SMILES Clc1cccc(CS(=O)(=O)N2CCCC[C@H]2C(=O)OCCCc2cccnc2)c1 |r| Show InChI InChI=1S/C21H25ClN2O4S/c22-19-9-3-6-18(14-19)16-29(26,27)24-12-2-1-10-20(24)21(25)28-13-5-8-17-7-4-11-23-15-17/h3-4,6-7,9,11,14-15,20H,1-2,5,8,10,12-13,16H2/t20-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200288
(CHEMBL3921322)Show SMILES O=C(OCCOc1cccnc1)[C@@H]1CCCCN1S(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C20H24N2O5S/c23-20(27-14-13-26-18-9-6-11-21-15-18)19-10-4-5-12-22(19)28(24,25)16-17-7-2-1-3-8-17/h1-3,6-9,11,15,19H,4-5,10,12-14,16H2/t19-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200288
(CHEMBL3921322)Show SMILES O=C(OCCOc1cccnc1)[C@@H]1CCCCN1S(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C20H24N2O5S/c23-20(27-14-13-26-18-9-6-11-21-15-18)19-10-4-5-12-22(19)28(24,25)16-17-7-2-1-3-8-17/h1-3,6-9,11,15,19H,4-5,10,12-14,16H2/t19-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200321
(CHEMBL3911322)Show SMILES [O-][N+](=O)c1cccc(CS(=O)(=O)N2CCCC[C@H]2C(=O)OCCCc2cccnc2)c1 |r| Show InChI InChI=1S/C21H25N3O6S/c25-21(30-13-5-8-17-7-4-11-22-15-17)20-10-1-2-12-23(20)31(28,29)16-18-6-3-9-19(14-18)24(26)27/h3-4,6-7,9,11,14-15,20H,1-2,5,8,10,12-13,16H2/t20-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200321
(CHEMBL3911322)Show SMILES [O-][N+](=O)c1cccc(CS(=O)(=O)N2CCCC[C@H]2C(=O)OCCCc2cccnc2)c1 |r| Show InChI InChI=1S/C21H25N3O6S/c25-21(30-13-5-8-17-7-4-11-22-15-17)20-10-1-2-12-23(20)31(28,29)16-18-6-3-9-19(14-18)24(26)27/h3-4,6-7,9,11,14-15,20H,1-2,5,8,10,12-13,16H2/t20-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200291
(CHEMBL3893328)Show SMILES COCCOc1cc(OCCOC)cc(c1)C(=O)OCCOC(=O)[C@@H]1CCCCN1S(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C28H37NO10S/c1-34-12-14-36-24-18-23(19-25(20-24)37-15-13-35-2)27(30)38-16-17-39-28(31)26-10-6-7-11-29(26)40(32,33)21-22-8-4-3-5-9-22/h3-5,8-9,18-20,26H,6-7,10-17,21H2,1-2H3/t26-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200291
(CHEMBL3893328)Show SMILES COCCOc1cc(OCCOC)cc(c1)C(=O)OCCOC(=O)[C@@H]1CCCCN1S(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C28H37NO10S/c1-34-12-14-36-24-18-23(19-25(20-24)37-15-13-35-2)27(30)38-16-17-39-28(31)26-10-6-7-11-29(26)40(32,33)21-22-8-4-3-5-9-22/h3-5,8-9,18-20,26H,6-7,10-17,21H2,1-2H3/t26-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200300
(CHEMBL3922939)Show SMILES [O-][N+](=O)c1cccc(CS(=O)(=O)N2CCCCC2C(=O)OCCCc2cccnc2)c1 Show InChI InChI=1S/C21H25N3O6S/c25-21(30-13-5-8-17-7-4-11-22-15-17)20-10-1-2-12-23(20)31(28,29)16-18-6-3-9-19(14-18)24(26)27/h3-4,6-7,9,11,14-15,20H,1-2,5,8,10,12-13,16H2 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200300
(CHEMBL3922939)Show SMILES [O-][N+](=O)c1cccc(CS(=O)(=O)N2CCCCC2C(=O)OCCCc2cccnc2)c1 Show InChI InChI=1S/C21H25N3O6S/c25-21(30-13-5-8-17-7-4-11-22-15-17)20-10-1-2-12-23(20)31(28,29)16-18-6-3-9-19(14-18)24(26)27/h3-4,6-7,9,11,14-15,20H,1-2,5,8,10,12-13,16H2 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.71E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50335224
(CHEMBL1650946 | rac-3-(3,4,5-trimethoxyphenyl)prop...)Show SMILES COc1cc(CCCOC(=O)C2CCCCN2S(=O)(=O)Cc2ccccc2)cc(OC)c1OC Show InChI InChI=1S/C25H33NO7S/c1-30-22-16-20(17-23(31-2)24(22)32-3)12-9-15-33-25(27)21-13-7-8-14-26(21)34(28,29)18-19-10-5-4-6-11-19/h4-6,10-11,16-17,21H,7-9,12-15,18H2,1-3H3 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wu£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of PPIase activity of Legionella pneumophila MIP protein expressed in Escherichia coli by spectrophotometry |
J Med Chem 54: 277-83 (2011)
Article DOI: 10.1021/jm101156y
BindingDB Entry DOI: 10.7270/Q2GF0VG2 |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200293
(CHEMBL3896009)Show SMILES O=C(OCCCc1cccnc1)C1CCCCN1S(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C21H26N2O4S/c24-21(27-15-7-11-18-10-6-13-22-16-18)20-12-4-5-14-23(20)28(25,26)17-19-8-2-1-3-9-19/h1-3,6,8-10,13,16,20H,4-5,7,11-12,14-15,17H2 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200293
(CHEMBL3896009)Show SMILES O=C(OCCCc1cccnc1)C1CCCCN1S(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C21H26N2O4S/c24-21(27-15-7-11-18-10-6-13-22-16-18)20-12-4-5-14-23(20)28(25,26)17-19-8-2-1-3-9-19/h1-3,6,8-10,13,16,20H,4-5,7,11-12,14-15,17H2 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200319
(CHEMBL3902318)Show SMILES O=C(OCCNC(=O)c1cccnc1)[C@@H]1CCCCN1S(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C21H25N3O5S/c25-20(18-9-6-11-22-15-18)23-12-14-29-21(26)19-10-4-5-13-24(19)30(27,28)16-17-7-2-1-3-8-17/h1-3,6-9,11,15,19H,4-5,10,12-14,16H2,(H,23,25)/t19-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200319
(CHEMBL3902318)Show SMILES O=C(OCCNC(=O)c1cccnc1)[C@@H]1CCCCN1S(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C21H25N3O5S/c25-20(18-9-6-11-22-15-18)23-12-14-29-21(26)19-10-4-5-13-24(19)30(27,28)16-17-7-2-1-3-8-17/h1-3,6-9,11,15,19H,4-5,10,12-14,16H2,(H,23,25)/t19-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200299
(CHEMBL3920840)Show SMILES C[C@H](CNC(=O)c1cccnc1)OC(=O)[C@@H]1CCCCN1S(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C22H27N3O5S/c1-17(14-24-21(26)19-10-7-12-23-15-19)30-22(27)20-11-5-6-13-25(20)31(28,29)16-18-8-3-2-4-9-18/h2-4,7-10,12,15,17,20H,5-6,11,13-14,16H2,1H3,(H,24,26)/t17-,20+/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200299
(CHEMBL3920840)Show SMILES C[C@H](CNC(=O)c1cccnc1)OC(=O)[C@@H]1CCCCN1S(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C22H27N3O5S/c1-17(14-24-21(26)19-10-7-12-23-15-19)30-22(27)20-11-5-6-13-25(20)31(28,29)16-18-8-3-2-4-9-18/h2-4,7-10,12,15,17,20H,5-6,11,13-14,16H2,1H3,(H,24,26)/t17-,20+/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200292
(CHEMBL3936855)Show SMILES COc1cc(CCCOC(=O)[C@H]2CCCCN2S(=O)(=O)Cc2ccccc2)cc(OC)c1OC |r| Show InChI InChI=1S/C25H33NO7S/c1-30-22-16-20(17-23(31-2)24(22)32-3)12-9-15-33-25(27)21-13-7-8-14-26(21)34(28,29)18-19-10-5-4-6-11-19/h4-6,10-11,16-17,21H,7-9,12-15,18H2,1-3H3/t21-/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.28E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200292
(CHEMBL3936855)Show SMILES COc1cc(CCCOC(=O)[C@H]2CCCCN2S(=O)(=O)Cc2ccccc2)cc(OC)c1OC |r| Show InChI InChI=1S/C25H33NO7S/c1-30-22-16-20(17-23(31-2)24(22)32-3)12-9-15-33-25(27)21-13-7-8-14-26(21)34(28,29)18-19-10-5-4-6-11-19/h4-6,10-11,16-17,21H,7-9,12-15,18H2,1-3H3/t21-/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200295
(CHEMBL3963890)Show SMILES Nc1ccc(CS(=O)(=O)N2CCCCC2C(=O)OCCCc2cccnc2)cc1 Show InChI InChI=1S/C21H27N3O4S/c22-19-10-8-18(9-11-19)16-29(26,27)24-13-2-1-7-20(24)21(25)28-14-4-6-17-5-3-12-23-15-17/h3,5,8-12,15,20H,1-2,4,6-7,13-14,16,22H2 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200295
(CHEMBL3963890)Show SMILES Nc1ccc(CS(=O)(=O)N2CCCCC2C(=O)OCCCc2cccnc2)cc1 Show InChI InChI=1S/C21H27N3O4S/c22-19-10-8-18(9-11-19)16-29(26,27)24-13-2-1-7-20(24)21(25)28-14-4-6-17-5-3-12-23-15-17/h3,5,8-12,15,20H,1-2,4,6-7,13-14,16,22H2 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50565512
(CHEMBL4798300)Show SMILES C[C@H]1C[C@H](C)C(=O)C(C1)[C@H](O)CC1CC(=O)N(CC(=O)NC2C3CC4CC2CC(O)(C4)C3)C(=O)C1 |r,wU:1.0,wD:3.3,9.10,TLB:29:28:21:23.25.24,25:26:31:23.24.30,25:24:21.26.27:31,THB:30:24:21:27.28.31,30:28:21:23.25.24,20:21:23.25.24:27.28.31,20:21:31:23.24.30,(-6.82,-3.14,;-6.82,-1.6,;-8.15,-.83,;-8.15,.71,;-9.49,1.48,;-6.82,1.49,;-6.82,3.03,;-5.49,.71,;-5.49,-.83,;-4.15,1.48,;-4.15,3.02,;-2.82,.71,;-1.49,1.48,;-1.49,3.02,;-.15,3.8,;-.15,5.34,;1.18,3.02,;2.52,3.79,;3.85,3.02,;3.85,1.48,;5.18,3.79,;6.52,3.02,;8.18,3.53,;9.08,2.46,;10.44,2.06,;8.94,1.47,;8.01,2.64,;8.8,4.01,;10.3,4.55,;11.07,5.88,;11.21,3.37,;8.91,4.81,;1.18,1.48,;2.52,.71,;-.15,.71,)| | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.18E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of Legionella pneumophila Mip assessed as reduction in PPIase activity using succinyl-Ala-Leu-Pro-Phe-4-nitroanilide as substrate incubate... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00911
BindingDB Entry DOI: 10.7270/Q22V2KW9 |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50335226
(3-(3,4,5-trimethoxyphenyl)propyl 1-(phenylsulfonyl...)Show SMILES COc1cc(CCCOC(=O)C2CCCCN2S(=O)(=O)c2ccccc2)cc(OC)c1OC Show InChI InChI=1S/C24H31NO7S/c1-29-21-16-18(17-22(30-2)23(21)31-3)10-9-15-32-24(26)20-13-7-8-14-25(20)33(27,28)19-11-5-4-6-12-19/h4-6,11-12,16-17,20H,7-10,13-15H2,1-3H3 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wu£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of PPIase activity of Legionella pneumophila MIP protein expressed in Escherichia coli by spectrophotometry |
J Med Chem 54: 277-83 (2011)
Article DOI: 10.1021/jm101156y
BindingDB Entry DOI: 10.7270/Q2GF0VG2 |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50565513
(CHEMBL4779246)Show SMILES C[C@H]1C[C@H](C)C(=O)C(C1)[C@H](O)CC1CC(=O)N(CC(=O)N(C)C(C)(C)C)C(=O)C1 |r| | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of Legionella pneumophila Mip assessed as reduction in PPIase activity using succinyl-Ala-Leu-Pro-Phe-4-nitroanilide as substrate incubate... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00911
BindingDB Entry DOI: 10.7270/Q22V2KW9 |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50335227
(3-(pyridin-3-yl)propyl 1-(3-nitrophenylsulfonyl)pi...)Show SMILES [O-][N+](=O)c1cccc(c1)S(=O)(=O)N1CCCCC1C(=O)OCCCc1cccnc1 Show InChI InChI=1S/C20H23N3O6S/c24-20(29-13-5-7-16-6-4-11-21-15-16)19-10-1-2-12-22(19)30(27,28)18-9-3-8-17(14-18)23(25)26/h3-4,6,8-9,11,14-15,19H,1-2,5,7,10,12-13H2 | PDB
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UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wu£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of PPIase activity of Legionella pneumophila MIP protein expressed in Escherichia coli by spectrophotometry |
J Med Chem 54: 277-83 (2011)
Article DOI: 10.1021/jm101156y
BindingDB Entry DOI: 10.7270/Q2GF0VG2 |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200284
(CHEMBL3959376)Show SMILES CC(C)Nc1cccc(CS(=O)(=O)N2CCCCC2C(=O)OCCCc2cccnc2)c1 Show InChI InChI=1S/C24H33N3O4S/c1-19(2)26-22-11-5-8-21(16-22)18-32(29,30)27-14-4-3-12-23(27)24(28)31-15-7-10-20-9-6-13-25-17-20/h5-6,8-9,11,13,16-17,19,23,26H,3-4,7,10,12,14-15,18H2,1-2H3 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200284
(CHEMBL3959376)Show SMILES CC(C)Nc1cccc(CS(=O)(=O)N2CCCCC2C(=O)OCCCc2cccnc2)c1 Show InChI InChI=1S/C24H33N3O4S/c1-19(2)26-22-11-5-8-21(16-22)18-32(29,30)27-14-4-3-12-23(27)24(28)31-15-7-10-20-9-6-13-25-17-20/h5-6,8-9,11,13,16-17,19,23,26H,3-4,7,10,12,14-15,18H2,1-2H3 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
Outer membrane protein MIP
(Legionella pneumophila) | BDBM50200301
(CHEMBL3956723)Show SMILES CC(C)Nc1ccc(CS(=O)(=O)N2CCCCC2C(=O)OCCCc2cccnc2)cc1 Show InChI InChI=1S/C24H33N3O4S/c1-19(2)26-22-12-10-21(11-13-22)18-32(29,30)27-15-4-3-9-23(27)24(28)31-16-6-8-20-7-5-14-25-17-20/h5,7,10-14,17,19,23,26H,3-4,6,8-9,15-16,18H2,1-2H3 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of W£rzburg
Curated by ChEMBL
| Assay Description
Inhibition of Mip PPIase activity in Legionella pneumophila |
Bioorg Med Chem 24: 5134-5147 (2016)
Article DOI: 10.1016/j.bmc.2016.08.025
BindingDB Entry DOI: 10.7270/Q2GF0WGG |
More data for this
Ligand-Target Pair | |
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