Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM50342885 ((1S,2S,3S,4R,5S)-5-[4-Chloro-3-(4-ethoxybenzyl)phe...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.877 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of methyl alpha-D-glucopyranoside uptake after 1 hr | J Med Chem 54: 2952-60 (2011) Article DOI: 10.1021/jm200049r BindingDB Entry DOI: 10.7270/Q2NZ880H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM50342887 ((1S,2S,3S,4R,5S)-5-[4-Chloro-3-(4-methoxybenzyl)ph...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.882 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of methyl alpha-D-glucopyranoside uptake after 1 hr | J Med Chem 54: 2952-60 (2011) Article DOI: 10.1021/jm200049r BindingDB Entry DOI: 10.7270/Q2NZ880H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM50342889 ((1S,2S,3S,4R,5S)-1-(Hydroxymethyl)-5-[3-(4-methoxy...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.07 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of methyl alpha-D-glucopyranoside uptake after 1 hr | J Med Chem 54: 2952-60 (2011) Article DOI: 10.1021/jm200049r BindingDB Entry DOI: 10.7270/Q2NZ880H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM50342888 ((1S,2S,3S,4R,5S)-5-[3-(4-Ethoxybenzyl)-4-methylphe...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.11 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of methyl alpha-D-glucopyranoside uptake after 1 hr | J Med Chem 54: 2952-60 (2011) Article DOI: 10.1021/jm200049r BindingDB Entry DOI: 10.7270/Q2NZ880H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM20880 ((2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)me...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.35 | n/a | n/a | n/a | n/a | n/a | n/a |
Green Cross Corporation Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells using methyl-alpha-D-glucopyranoside by liquid scintillation counting | Bioorg Med Chem Lett 21: 3759-63 (2011) Article DOI: 10.1016/j.bmcl.2011.04.063 BindingDB Entry DOI: 10.7270/Q2NC61KM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM109275 (US8609622, 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.42 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM109278 (US8609622, 5) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.49 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM109277 (US8609622, 4) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.31 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM109275 (US8609622, 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.65 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM109279 (US8609622, 7) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.58 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM20878 ((2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{2-[(4-methox...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 mins | Bioorg Med Chem 19: 5334-41 (2011) Article DOI: 10.1016/j.bmc.2011.08.005 BindingDB Entry DOI: 10.7270/Q2F1903R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM50302603 ((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assay | J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM50302603 ((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assay | J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM109277 (US8609622, 4) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6.35 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM109277 (US8609622, 4) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6.92 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM50313368 ((6S,7R,8R,9S)-6-(3-(4-methoxybenzyl)-4-methylpheny...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.98 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of methyl alpha-D-glucopyranoside uptake after 1 hr | J Med Chem 54: 2952-60 (2011) Article DOI: 10.1021/jm200049r BindingDB Entry DOI: 10.7270/Q2NZ880H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM50302617 ((2S,3R,4R,5S)-2-[4-Chloro-3-(4-hydroxy-benzyl)-phe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assay | J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM109276 (US8609622, 3) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 8.08 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM109280 (US8609622, 9) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 9.28 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM50302616 ((2S,3R,4R,5S)-2-(4-Chloro-3-(4-(2-hydroxyethoxy)be...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assay | J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM109274 (US8609622, 1) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 9.53 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM50351435 (CHEMBL1819489) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 mins | Bioorg Med Chem 19: 5334-41 (2011) Article DOI: 10.1016/j.bmc.2011.08.005 BindingDB Entry DOI: 10.7270/Q2F1903R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM50302625 ((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assay | J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM50302625 ((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assay | J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 mins | Bioorg Med Chem 19: 5334-41 (2011) Article DOI: 10.1016/j.bmc.2011.08.005 BindingDB Entry DOI: 10.7270/Q2F1903R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM50302615 ((2S,3R,4R,5S)-2-{4-Chloro-3-[4-(2-methoxy-ethoxy)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assay | J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM50351439 (CHEMBL1819492) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 mins | Bioorg Med Chem 19: 5334-41 (2011) Article DOI: 10.1016/j.bmc.2011.08.005 BindingDB Entry DOI: 10.7270/Q2F1903R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM50302624 ((2S,3R,4R,5S)-2-[4-Chloro-3-(4-ethoxy-benzyl)-phen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assay | J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM50302609 ((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assay | J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM50302623 ((2S,3R,4R,5S)-2-(3-(4-Ethoxybenzyl)-4-methylphenyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assay | J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM50351432 (CHEMBL1819486) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 mins | Bioorg Med Chem 19: 5334-41 (2011) Article DOI: 10.1016/j.bmc.2011.08.005 BindingDB Entry DOI: 10.7270/Q2F1903R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM50351436 (CHEMBL1819490) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 mins | Bioorg Med Chem 19: 5334-41 (2011) Article DOI: 10.1016/j.bmc.2011.08.005 BindingDB Entry DOI: 10.7270/Q2F1903R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM50351437 (CHEMBL1819491) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 mins | Bioorg Med Chem 19: 5334-41 (2011) Article DOI: 10.1016/j.bmc.2011.08.005 BindingDB Entry DOI: 10.7270/Q2F1903R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM50342886 ((1S,2S,3S,4S,5S)-5-[4-Chloro-3-(4-methoxybenzyl)-p...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 43.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of methyl alpha-D-glucopyranoside uptake after 1 hr | J Med Chem 54: 2952-60 (2011) Article DOI: 10.1021/jm200049r BindingDB Entry DOI: 10.7270/Q2NZ880H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM50302619 (CHEMBL567572 | [2-Chloro-5-((2S,3R,4R,5S,6S)-3,4,5...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assay | J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM50351431 (CHEMBL1819485) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 mins | Bioorg Med Chem 19: 5334-41 (2011) Article DOI: 10.1016/j.bmc.2011.08.005 BindingDB Entry DOI: 10.7270/Q2F1903R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM50345019 ((2R,3S,4R,5R,6S)-2-(hydroxymethyl)-6-(3-(4-(pent-2...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 59.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Green Cross Corporation Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells using methyl-alpha-D-glucopyranoside by liquid scintillation counting | Bioorg Med Chem Lett 21: 3759-63 (2011) Article DOI: 10.1016/j.bmcl.2011.04.063 BindingDB Entry DOI: 10.7270/Q2NC61KM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM50302613 ((2S,3R,4R,5S)-2-(4-Chloro-3-(4-(thiazol-2-yloxy)be...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assay | J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM50345022 ((2R,3S,4R,5R,6S)-2-Hydroxymethyl-6-(15-oxa-tricycl...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 81.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Green Cross Corporation Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells using methyl-alpha-D-glucopyranoside by liquid scintillation counting | Bioorg Med Chem Lett 21: 3759-63 (2011) Article DOI: 10.1016/j.bmcl.2011.04.063 BindingDB Entry DOI: 10.7270/Q2NC61KM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM50345020 ((2R,3S,4R,5R,6S)-2-Hydroxymethyl-6-(15-oxa-tricycl...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 89.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Green Cross Corporation Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells using methyl-alpha-D-glucopyranoside by liquid scintillation counting | Bioorg Med Chem Lett 21: 3759-63 (2011) Article DOI: 10.1016/j.bmcl.2011.04.063 BindingDB Entry DOI: 10.7270/Q2NC61KM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM50342884 ((1S,2S,3S,4S,5S)-5-[4-Chloro-3-(4-ethoxybenzyl)-ph...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 89.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of methyl alpha-D-glucopyranoside uptake after 1 hr | J Med Chem 54: 2952-60 (2011) Article DOI: 10.1021/jm200049r BindingDB Entry DOI: 10.7270/Q2NZ880H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM50302614 ((2R,3S,4S,5R)-2-(4-Chloro-3-(4-((S)-1-methylpyrrol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 92 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assay | J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM50345023 ((2R,3S,4R,5R,6S)-2-Hydroxymethyl-6-(16-oxa-tricycl...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 99.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Green Cross Corporation Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells using methyl-alpha-D-glucopyranoside by liquid scintillation counting | Bioorg Med Chem Lett 21: 3759-63 (2011) Article DOI: 10.1016/j.bmcl.2011.04.063 BindingDB Entry DOI: 10.7270/Q2NC61KM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM50302604 ((3S,4R,5R,6S)-6-[4-Chloro-3-(4-ethoxy-benzyl)-phen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assay | J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Mus musculus (Mouse)) | BDBM50302621 ((2S,3R,4R,5S)-2-(4-Chloro-3-(4-methoxyphenylthio)p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assay | J Med Chem 52: 6201-4 (2009) Article DOI: 10.1021/jm900951n BindingDB Entry DOI: 10.7270/Q2F76DH1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM50345021 ((2R,3S,4R,5R,6S)-2-Hydroxymethyl-6-(16-oxa-tricycl...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 103 | n/a | n/a | n/a | n/a | n/a | n/a |
Green Cross Corporation Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells using methyl-alpha-D-glucopyranoside by liquid scintillation counting | Bioorg Med Chem Lett 21: 3759-63 (2011) Article DOI: 10.1016/j.bmcl.2011.04.063 BindingDB Entry DOI: 10.7270/Q2NC61KM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM50351438 (CHEMBL1817688) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 mins | Bioorg Med Chem 19: 5334-41 (2011) Article DOI: 10.1016/j.bmc.2011.08.005 BindingDB Entry DOI: 10.7270/Q2F1903R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM50351433 (CHEMBL1819487) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 mins | Bioorg Med Chem 19: 5334-41 (2011) Article DOI: 10.1016/j.bmc.2011.08.005 BindingDB Entry DOI: 10.7270/Q2F1903R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM50351443 (CHEMBL1819496) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 mins | Bioorg Med Chem 19: 5334-41 (2011) Article DOI: 10.1016/j.bmc.2011.08.005 BindingDB Entry DOI: 10.7270/Q2F1903R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 5 member 4 (Homo sapiens (Human)) | BDBM50351442 (CHEMBL1819495) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 mins | Bioorg Med Chem 19: 5334-41 (2011) Article DOI: 10.1016/j.bmc.2011.08.005 BindingDB Entry DOI: 10.7270/Q2F1903R | |||||||||||
More data for this Ligand-Target Pair |
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