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Compile Data Set for Download or QSAR

Found 7 hits of ic50 data for polymerid = 50005670   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leucine--tRNA ligase, cytoplasmic


(Saccharomyces cerevisiae S288c)
BDBM50370987
PNG
(TAVABOROLE)
Show SMILES OB1OCc2cc(F)ccc12
Show InChI InChI=1S/C7H6BFO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3,10H,4H2
KEGG

UniProtKB/SwissProt

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DrugBank
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.10E+3n/an/an/an/an/an/a



Anacor Pharmaceuticals, Inc

Curated by ChEMBL


Assay Description
Inhibition of Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase assessed as tRNA amino-acylation


Science 316: 1759-1761 (2007)


Article DOI: 10.1126/science.1142189
BindingDB Entry DOI: 10.7270/Q2P84CQ2
More data for this
Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic


(Saccharomyces cerevisiae S288c)
BDBM50370990
PNG
(CHEMBL214011)
Show SMILES OB1OCCc2cc(F)ccc12
Show InChI InChI=1S/C8H8BFO2/c10-7-1-2-8-6(5-7)3-4-12-9(8)11/h1-2,5,11H,3-4H2
KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.60E+4n/an/an/an/an/an/a



Anacor Pharmaceuticals, Inc

Curated by ChEMBL


Assay Description
Inhibition of Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase assessed as tRNA amino-acylation


Science 316: 1759-1761 (2007)


Article DOI: 10.1126/science.1142189
BindingDB Entry DOI: 10.7270/Q2P84CQ2
More data for this
Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic


(Saccharomyces cerevisiae S288c)
BDBM50370989
PNG
(CHEMBL226398)
Show SMILES Fc1ccc2C(=O)OCc2c1
Show InChI InChI=1S/C8H5FO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3H,4H2
KEGG

UniProtKB/SwissProt

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CHEMBL
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Anacor Pharmaceuticals, Inc

Curated by ChEMBL


Assay Description
Inhibition of Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase assessed as tRNA amino-acylation


Science 316: 1759-1761 (2007)


Article DOI: 10.1126/science.1142189
BindingDB Entry DOI: 10.7270/Q2P84CQ2
More data for this
Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic


(Saccharomyces cerevisiae S288c)
BDBM50370992
PNG
(CHEMBL226509)
Show SMILES OC1OCc2cc(F)ccc12 |w:1.0|
Show InChI InChI=1S/C8H7FO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3,8,10H,4H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Anacor Pharmaceuticals, Inc

Curated by ChEMBL


Assay Description
Inhibition of Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase assessed as tRNA amino-acylation


Science 316: 1759-1761 (2007)


Article DOI: 10.1126/science.1142189
BindingDB Entry DOI: 10.7270/Q2P84CQ2
More data for this
Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic


(Saccharomyces cerevisiae S288c)
BDBM50370991
PNG
(CHEMBL388368)
Show SMILES COCc1cc(F)ccc1B(O)O
Show InChI InChI=1S/C8H10BFO3/c1-13-5-6-4-7(10)2-3-8(6)9(11)12/h2-4,11-12H,5H2,1H3
KEGG

UniProtKB/SwissProt

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CHEMBL
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Anacor Pharmaceuticals, Inc

Curated by ChEMBL


Assay Description
Inhibition of Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase assessed as tRNA amino-acylation


Science 316: 1759-1761 (2007)


Article DOI: 10.1126/science.1142189
BindingDB Entry DOI: 10.7270/Q2P84CQ2
More data for this
Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic


(Saccharomyces cerevisiae S288c)
BDBM26128
PNG
((4-fluorophenyl)boranediol | CHEMBL344890 | Phenyl...)
Show SMILES OB(O)c1ccc(F)cc1
Show InChI InChI=1S/C6H6BFO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4,9-10H
KEGG

UniProtKB/SwissProt

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CHEMBL
MCE
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Anacor Pharmaceuticals, Inc

Curated by ChEMBL


Assay Description
Inhibition of Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase assessed as tRNA amino-acylation


Science 316: 1759-1761 (2007)


Article DOI: 10.1126/science.1142189
BindingDB Entry DOI: 10.7270/Q2P84CQ2
More data for this
Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic


(Saccharomyces cerevisiae S288c)
BDBM50370988
PNG
(CHEMBL225804)
Show SMILES Cc1cc(F)ccc1B(O)O
Show InChI InChI=1S/C7H8BFO2/c1-5-4-6(9)2-3-7(5)8(10)11/h2-4,10-11H,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Anacor Pharmaceuticals, Inc

Curated by ChEMBL


Assay Description
Inhibition of Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase assessed as tRNA amino-acylation


Science 316: 1759-1761 (2007)


Article DOI: 10.1126/science.1142189
BindingDB Entry DOI: 10.7270/Q2P84CQ2
More data for this
Ligand-Target Pair