Found 71 hits of ic50 data for polymerid = 50005760 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607682
(CHEMBL5220685)Show SMILES COC(=O)[C@H]1COCCN1CCOc1ccccc1Cc1cn(nc1-c1cc(Cl)nc(N)n1)C(F)F |r| | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607678
(CHEMBL5218878)Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCNC(=O)C1)C(F)F | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607681
(CHEMBL5218552)Show SMILES COC(=O)[C@@H]1COCCN1CCOc1ccccc1Cc1cn(nc1-c1cc(Cl)nc(N)n1)C(F)F |r| | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607679
(CHEMBL5218615)Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCS(=O)(=O)CC1)C(F)F | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607686
(CHEMBL5219830)Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCOC[C@H]1CO)C(F)F |r| | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607683
(CHEMBL5219579)Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCO[C@@H](CO)C1)C(F)F |r| | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607676
(CHEMBL5218698)Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCOCC1)C(F)F | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607680
(CHEMBL5218702)Show SMILES CC1(O)CCN(CCOc2ccccc2Cc2cn(nc2-c2cc(Cl)nc(N)n2)C(F)F)CC1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607685
(CHEMBL5220647)Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCOC[C@@H]1CO)C(F)F |r| | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607684
(CHEMBL5219443)Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCO[C@H](CO)C1)C(F)F |r| | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607673
(CHEMBL5220895)Show SMILES Cn1cc(Cc2ccccc2OCCN2CC3CC(C2)O3)c(n1)-c1cc(Cl)nc(N)n1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607674
(CHEMBL5220347)Show SMILES Cn1cc(Cc2ccccc2OCCN2CC3(COC3)C2)c(n1)-c1cc(Cl)nc(N)n1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607672
(CHEMBL5220723)Show SMILES Cn1cc(Cc2ccccc2OCCN2CCOCC2)c(n1)-c1cc(Cl)nc(N)n1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607675
(CHEMBL5219922)Show SMILES Cn1cc(Cc2ccccc2OCCN2CCNC(=O)C2)c(n1)-c1cc(Cl)nc(N)n1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607667
(CHEMBL5219530) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607677
(CHEMBL5220632)Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCC(=O)N1CCOCC1)C(F)F | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577248
(CHEMBL4878379)Show SMILES COC(=O)c1c(Cc2ccccc2)c(nn1C)-c1cc(Cl)nc(N)n1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607660
(CHEMBL5221008) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607666
(CHEMBL5220075) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577241
(CHEMBL4848035) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607671
(CHEMBL5221093)Show SMILES Cn1cc(Cc2ccccc2Oc2ccccc2)c(n1)-c1cc(Cl)nc(N)n1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577242
(CHEMBL4854762) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 92 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human soluble adenylyl cyclase transfected (4-4 clones)in human HEK293 cells assessed as reduction in cAMP levels preincubated for 5 mi... |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577241
(CHEMBL4848035) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 102 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human soluble adenylyl cyclase transfected (4-4 clones)in human HEK293 cells assessed as reduction in cAMP levels preincubated for 5 mi... |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577243
(CHEMBL4868801) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 107 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607662
(CHEMBL5219193) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 112 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577244
(CHEMBL4864668) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577236
(CHEMBL4857305) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 132 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577232
(CHEMBL4849033) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 141 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577242
(CHEMBL4854762) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 159 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577242
(CHEMBL4854762) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577242
(CHEMBL4854762) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 195 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577232
(CHEMBL4849033) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 196 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human soluble adenylyl cyclase transfected (4-4 clones)in human HEK293 cells assessed as reduction in cAMP levels preincubated for 5 mi... |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577233
(CHEMBL4874288) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 225 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human soluble adenylyl cyclase transfected (4-4 clones)in human HEK293 cells assessed as reduction in cAMP levels preincubated for 5 mi... |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577245
(CHEMBL4866319) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 325 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577234
(CHEMBL4864843) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 342 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577235
(CHEMBL4867202) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 351 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577235
(CHEMBL4867202) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 351 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607664
(CHEMBL5219159) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 389 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577233
(CHEMBL4874288) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 392 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607669
(CHEMBL5219933)Show SMILES COC(=O)c1cccc(Cc2cn(C)nc2-c2cc(Cl)nc(N)n2)c1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 436 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607661
(CHEMBL5220308) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 469 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577238
(CHEMBL4866035) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 576 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50262191
({[(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-2-methyloxo...)Show SMILES C[C@H]1O[C@H](C[C@@H]1OP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C10H16N5O11P3/c1-5-6(24-28(19,20)26-29(21,22)25-27(16,17)18)2-7(23-5)15-4-14-8-9(11)12-3-13-10(8)15/h3-7H,2H2,1H3,(H,19,20)(H,21,22)(H2,11,12,13)(H2,16,17,18)/p-3/t5-,6+,7-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Ruhr-University Bochum
Curated by ChEMBL
| Assay Description Inhibition of human recombinant soluble adenylyl cyclase |
J Med Chem 51: 4456-64 (2008)
Article DOI: 10.1021/jm800481q BindingDB Entry DOI: 10.7270/Q22N5355 |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577249
(CHEMBL4878049)Show SMILES Cn1nc(c(Cc2ccccc2)c1C(O)=O)-c1cc(Cl)nc(N)n1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607663
(CHEMBL5219011) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 716 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50607659
(CHEMBL5218555) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 829 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577237
(CHEMBL4874934) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 989 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577239
(CHEMBL4862670) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577240
(CHEMBL4847756) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ |
More data for this Ligand-Target Pair | |
Adenylate cyclase type 10
(Homo sapiens (Human)) | BDBM50577237
(CHEMBL4874934) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B |
More data for this Ligand-Target Pair | |