Compile Data Set for Download or QSAR

Found 87 hits of ic50 data for polymerid = 50006690,5042,5043   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lipoxygenase (Glycine max)	BDBM50505285 (CHEMBL4450603) Show SMILES CC(=O)Nc1cccc(OC(=O)\C=C\c2cccc(Oc3ccccc3)c2)c1 Show InChI InChI=1S/C23H19NO4/c1-17(25)24-19-8-6-12-22(16-19)28-23(26)14-13-18-7-5-11-21(15-18)27-20-9-3-2-4-10-20/h2-16H,1H3,(H,24,25)/b14-13+	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of soya bean LOX assessed as reduction in formation of 13-hydroperoxylinoleic acid using sodium linoleate as substrate				J Med Chem 62: 8881-8914 (2019) Article DOI: 10.1021/acs.jmedchem.9b00017 BindingDB Entry DOI: 10.7270/Q27084PF
					More data for this Ligand-Target Pair
Lipoxygenase (Glycine max)	BDBM32020 (4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...) Show SMILES CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1 Show InChI InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
IQOG, CSIC Curated by ChEMBL					Assay Description Inhibition of soybean lipoxygenase using sodium linoleate as substrate by UV-based analysis				J Med Chem 62: 2184-2201 (2019) Article DOI: 10.1021/acs.jmedchem.8b01987 BindingDB Entry DOI: 10.7270/Q2MC93HC
					More data for this Ligand-Target Pair
Lipoxygenase (Glycine max)	BDBM50276365 (CHEMBL4127281) Show SMILES Oc1c(\C=C\n2cnc3c(ncnc23)N2CCCCC2)c(=O)oc2ccccc12 Show InChI InChI=1S/C21H19N5O3/c27-18-14-6-2-3-7-16(14)29-21(28)15(18)8-11-26-13-24-17-19(22-12-23-20(17)26)25-9-4-1-5-10-25/h2-3,6-8,11-13,27H,1,4-5,9-10H2/b11-8+	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbottabad University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of soybean lipoxygenase				Bioorg Med Chem 26: 3731-3762 (2018) Article DOI: 10.1016/j.bmc.2018.05.042 BindingDB Entry DOI: 10.7270/Q29889HN
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86082 (Tetraketone, 19) Show SMILES CC1(C)CC(=O)C(C(C2C(=O)CC(C)(C)CC2=O)c2ccc(\C=C\c3ccccc3)cc2)C(=O)C1 Show InChI InChI=1S/C31H34O4/c1-30(2)16-23(32)28(24(33)17-30)27(29-25(34)18-31(3,4)19-26(29)35)22-14-12-21(13-15-22)11-10-20-8-6-5-7-9-20/h5-15,27-29H,16-19H2,1-4H3/b11-10+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Lipoxygenase (Glycine max)	BDBM50282770 (CHEMBL2296824) Show SMILES CCCc1nc(nc2Sc3ccccc3Nc12)N1CCN(C)CC1 Show InChI InChI=1S/C18H23N5S/c1-3-6-14-16-17(24-15-8-5-4-7-13(15)19-16)21-18(20-14)23-11-9-22(2)10-12-23/h4-5,7-8,19H,3,6,9-12H2,1-2H3	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Medical University of Silesia Curated by ChEMBL					Assay Description Inhibition of soybean lipoxygenase				Eur J Med Chem 138: 774-806 (2017) Article DOI: 10.1016/j.ejmech.2017.07.009 BindingDB Entry DOI: 10.7270/Q26H4KZR
					More data for this Ligand-Target Pair
Lipoxygenase (Glycine max)	BDBM32020 (4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...) Show SMILES CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1 Show InChI InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universiti Kebangsaan Malaysia Curated by ChEMBL					Assay Description Inhibition of soybean lipoxygenase after 5 mins by colorimetric assay				Bioorg Med Chem 22: 4151-61 (2014) Article DOI: 10.1016/j.bmc.2014.05.052 BindingDB Entry DOI: 10.7270/Q2GX4D6F
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86085 (Tetraketone, 22) Show SMILES Cc1ccc(o1)C(C1C(=O)CC(C)(C)CC1=O)C1C(=O)CC(C)(C)CC1=O Show InChI InChI=1S/C22H28O5/c1-12-6-7-17(27-12)20(18-13(23)8-21(2,3)9-14(18)24)19-15(25)10-22(4,5)11-16(19)26/h6-7,18-20H,8-11H2,1-5H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86070 (Tetraketone, 3) Show SMILES Cc1ccc(cc1)C(C1C(=O)CC(C)(C)CC1=O)C1C(=O)CC(C)(C)CC1=O Show InChI InChI=1S/C24H30O4/c1-14-6-8-15(9-7-14)20(21-16(25)10-23(2,3)11-17(21)26)22-18(27)12-24(4,5)13-19(22)28/h6-9,20-22H,10-13H2,1-5H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.63E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86077 (Tetraketone, 11) Show SMILES CN(C)c1ccc(cc1)C(C1C(=O)CC(C)(C)CC1=O)C1C(=O)CC(C)(C)CC1=O Show InChI InChI=1S/C25H33NO4/c1-24(2)11-17(27)22(18(28)12-24)21(15-7-9-16(10-8-15)26(5)6)23-19(29)13-25(3,4)14-20(23)30/h7-10,21-23H,11-14H2,1-6H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Lipoxygenase (Glycine max)	BDBM50276370 (CHEMBL4126039) Show SMILES Oc1c(\C=C\n2cnc3c(NCc4ccccc4)ncnc23)c(=O)oc2ccccc12 Show InChI InChI=1S/C23H17N5O3/c29-20-16-8-4-5-9-18(16)31-23(30)17(20)10-11-28-14-27-19-21(25-13-26-22(19)28)24-12-15-6-2-1-3-7-15/h1-11,13-14,29H,12H2,(H,24,25,26)/b11-10+	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbottabad University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of soybean lipoxygenase				Bioorg Med Chem 26: 3731-3762 (2018) Article DOI: 10.1016/j.bmc.2018.05.042 BindingDB Entry DOI: 10.7270/Q29889HN
					More data for this Ligand-Target Pair
Lipoxygenase (Glycine max)	BDBM192766 (4-MMPB) Show SMILES CN1CCN(CC1)c1nc(C)c2Nc3ccccc3Sc2n1 Show InChI InChI=1S/C16H19N5S/c1-11-14-15(22-13-6-4-3-5-12(13)18-14)19-16(17-11)21-9-7-20(2)8-10-21/h3-6,18H,7-10H2,1-2H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Medical University of Silesia Curated by ChEMBL					Assay Description Inhibition of soybean lipoxygenase using linoleic acid as substrate preincubated for 5 mins followed by substrate addition measuredf after 7 mins by ...				Eur J Med Chem 138: 774-806 (2017) Article DOI: 10.1016/j.ejmech.2017.07.009 BindingDB Entry DOI: 10.7270/Q26H4KZR
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86074 (Tetraketone, 8) Show SMILES COc1ccc(cc1)C(C1C(=O)CC(C)(C)CC1=O)C1C(=O)CC(C)(C)CC1=O Show InChI InChI=1S/C24H30O5/c1-23(2)10-16(25)21(17(26)11-23)20(14-6-8-15(29-5)9-7-14)22-18(27)12-24(3,4)13-19(22)28/h6-9,20-22H,10-13H2,1-5H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.13E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM50009001 (5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...) Show SMILES Oc1cc2oc(cc(=O)c2c(O)c1O)-c1ccccc1 Show InChI InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description LOX inhibiting activity was measured by modifying the spectrophotometric method developed by Tappel.				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86072 (Tetraketone, 6) Show SMILES CC1(C)CC(=O)C(C(C2C(=O)CC(C)(C)CC2=O)c2ccc(O)cc2)C(=O)C1 Show InChI InChI=1S/C23H28O5/c1-22(2)9-15(25)20(16(26)10-22)19(13-5-7-14(24)8-6-13)21-17(27)11-23(3,4)12-18(21)28/h5-8,19-21,24H,9-12H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.64E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86080 (Tetraketone, 15) Show SMILES CC1(C)CC(=O)C(C(C2C(=O)CC(C)(C)CC2=O)c2ccc(O)c(Br)c2)C(=O)C1 Show InChI InChI=1S/C23H27BrO5/c1-22(2)8-15(26)20(16(27)9-22)19(12-5-6-14(25)13(24)7-12)21-17(28)10-23(3,4)11-18(21)29/h5-7,19-21,25H,8-11H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.71E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Lipoxygenase (Glycine max)	BDBM32020 (4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...) Show SMILES CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1 Show InChI InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbottabad University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of soybean lipoxygenase				Bioorg Med Chem 26: 3731-3762 (2018) Article DOI: 10.1016/j.bmc.2018.05.042 BindingDB Entry DOI: 10.7270/Q29889HN
					More data for this Ligand-Target Pair
Lipoxygenase (Glycine max)	BDBM32020 (4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...) Show SMILES CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1 Show InChI InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Zagreb Curated by ChEMBL					Assay Description Inhibition of soybean LOX using sodium linoleate as substrate by spectrophotometry				Eur J Med Chem 86: 502-14 (2014) Article DOI: 10.1016/j.ejmech.2014.09.013 BindingDB Entry DOI: 10.7270/Q2Z89F0V
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86078 (Tetraketone, 12) Show SMILES CC1(C)CC(=O)C(C(C2C(=O)CC(C)(C)CC2=O)c2ccccc2Cl)C(=O)C1 Show InChI InChI=1S/C23H27ClO4/c1-22(2)9-15(25)20(16(26)10-22)19(13-7-5-6-8-14(13)24)21-17(27)11-23(3,4)12-18(21)28/h5-8,19-21H,9-12H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.84E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Lipoxygenase (Glycine max)	BDBM50021468 (CHEMBL3289934) Show SMILES CN(C)c1ccc(\C=C2\CCC\C(=C/c3ccc(cc3[N+]([O-])=O)N(C)C)C2=O)c(c1)[N+]([O-])=O Show InChI InChI=1S/C24H26N4O5/c1-25(2)20-10-8-16(22(14-20)27(30)31)12-18-6-5-7-19(24(18)29)13-17-9-11-21(26(3)4)15-23(17)28(32)33/h8-15H,5-7H2,1-4H3/b18-12-,19-13+	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universiti Kebangsaan Malaysia Curated by ChEMBL					Assay Description Inhibition of soybean lipoxygenase after 5 mins by colorimetric assay				Bioorg Med Chem 22: 4151-61 (2014) Article DOI: 10.1016/j.bmc.2014.05.052 BindingDB Entry DOI: 10.7270/Q2GX4D6F
					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM86103 (3'-Hydroxyepiglucoisatisin, 3) Show SMILES OCC1OC(SC(CC(OC(=O)CC2(O)C(=O)Nc3ccccc23)C=C)=NOS(O)(=O)=O)C(O)C(O)C1O |w:26.28| Show InChI InChI=1S/C21H26N2O13S2/c1-2-10(34-15(25)8-21(30)11-5-3-4-6-12(11)22-20(21)29)7-14(23-36-38(31,32)33)37-19-18(28)17(27)16(26)13(9-24)35-19/h2-6,10,13,16-19,24,26-28,30H,1,7-9H2,(H,22,29)(H,31,32,33)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.06E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description LOX inhibiting activity was measured by modifying the spectrophotometric method developed by Tappel.				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86076 (Tetraketone, 10) Show SMILES CCOc1ccc(cc1)C(C1C(=O)CC(C)(C)CC1=O)C1C(=O)CC(C)(C)CC1=O Show InChI InChI=1S/C25H32O5/c1-6-30-16-9-7-15(8-10-16)21(22-17(26)11-24(2,3)12-18(22)27)23-19(28)13-25(4,5)14-20(23)29/h7-10,21-23H,6,11-14H2,1-5H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.08E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Lipoxygenase (Glycine max)	BDBM50531971 (CHEMBL4539028) Show SMILES CC(C)(C)[N+](\[O-])=C\c1cc2ccccc2nc1Cl Show InChI InChI=1S/C14H15ClN2O/c1-14(2,3)17(18)9-11-8-10-6-4-5-7-12(10)16-13(11)15/h4-9H,1-3H3/b17-9-	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
IQOG, CSIC Curated by ChEMBL					Assay Description Inhibition of soybean lipoxygenase using sodium linoleate as substrate by UV-based analysis				J Med Chem 62: 2184-2201 (2019) Article DOI: 10.1021/acs.jmedchem.8b01987 BindingDB Entry DOI: 10.7270/Q2MC93HC
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86069 (Tetraketone, 2) Show SMILES CC1(C)CC(=O)C(C(C2C(=O)CC(C)(C)CC2=O)c2ccccc2)C(=O)C1 Show InChI InChI=1S/C23H28O4/c1-22(2)10-15(24)20(16(25)11-22)19(14-8-6-5-7-9-14)21-17(26)12-23(3,4)13-18(21)27/h5-9,19-21H,10-13H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86075 (Tetraketone, 9) Show SMILES COc1ccc(C(C2C(=O)CC(C)(C)CC2=O)C2C(=O)CC(C)(C)CC2=O)c(OC)c1 Show InChI InChI=1S/C25H32O6/c1-24(2)10-16(26)22(17(27)11-24)21(15-8-7-14(30-5)9-20(15)31-6)23-18(28)12-25(3,4)13-19(23)29/h7-9,21-23H,10-13H2,1-6H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.31E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM86102 (Epiglucoisatisin, 2) Show SMILES OCC1OC(SC(CC(OC(=O)CC2C(=O)Nc3ccccc23)C=C)=NOS(O)(=O)=O)C(O)C(O)C1O |w:25.27| Show InChI InChI=1S/C21H26N2O12S2/c1-2-10(33-16(25)8-12-11-5-3-4-6-13(11)22-20(12)29)7-15(23-35-37(30,31)32)36-21-19(28)18(27)17(26)14(9-24)34-21/h2-6,10,12,14,17-19,21,24,26-28H,1,7-9H2,(H,22,29)(H,30,31,32)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.37E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description LOX inhibiting activity was measured by modifying the spectrophotometric method developed by Tappel.				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86083 (Tetraketone, 20) Show SMILES CC1(C)CC(=O)C(C(C2C(=O)CC(C)(C)CC2=O)c2ccc(cc2)C(\Br)=C\c2ccccc2)C(=O)C1 Show InChI InChI=1S/C31H33BrO4/c1-30(2)15-23(33)28(24(34)16-30)27(29-25(35)17-31(3,4)18-26(29)36)21-12-10-20(11-13-21)22(32)14-19-8-6-5-7-9-19/h5-14,27-29H,15-18H2,1-4H3/b22-14-	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.54E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Lipoxygenase (Glycine max)	BDBM50531968 (CHEMBL4575147) Show SMILES CC(C)(C)[N+](\[O-])=C\c1cc2ccccc2nc1O Show InChI InChI=1S/C14H16N2O2/c1-14(2,3)16(18)9-11-8-10-6-4-5-7-12(10)15-13(11)17/h4-9H,1-3H3,(H,15,17)/b16-9-	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
IQOG, CSIC Curated by ChEMBL					Assay Description Inhibition of soybean lipoxygenase using sodium linoleate as substrate by UV-based analysis				J Med Chem 62: 2184-2201 (2019) Article DOI: 10.1021/acs.jmedchem.8b01987 BindingDB Entry DOI: 10.7270/Q2MC93HC
					More data for this Ligand-Target Pair
Lipoxygenase (Glycine max)	BDBM50037298 (CHEMBL3356691) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#8]-c1ccc(cc1-[#8]-[#6]\[#6]=[#6](\[#6])-[#6])-c1c(-[#6])c2cc(Br)cc(Br)c2oc1=O Show InChI InChI=1S/C26H26Br2O4/c1-15(2)8-10-30-22-7-6-18(12-23(22)31-11-9-16(3)4)24-17(5)20-13-19(27)14-21(28)25(20)32-26(24)29/h6-9,12-14H,10-11H2,1-5H3	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of soybean LOX assessed as reduction in conversion of sodium linoleate to 13-hydroperoxylinoleic acid by UV spectroscopy				Bioorg Med Chem 22: 6586-94 (2015) Article DOI: 10.1016/j.bmc.2014.10.008 BindingDB Entry DOI: 10.7270/Q2MK6FHF
					More data for this Ligand-Target Pair
Lipoxygenase (Glycine max)	BDBM50045849 (CHEMBL3309949) Show SMILES CN(C)c1ccc(\C=C2/CN(C)C\C(=C/c3ccc(cc3[N+]([O-])=O)N(C)C)C2=O)c(c1)[N+]([O-])=O Show InChI InChI=1S/C24H27N5O5/c1-25(2)20-8-6-16(22(12-20)28(31)32)10-18-14-27(5)15-19(24(18)30)11-17-7-9-21(26(3)4)13-23(17)29(33)34/h6-13H,14-15H2,1-5H3/b18-10+,19-11+	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universiti Kebangsaan Malaysia Curated by ChEMBL					Assay Description Inhibition of soybean lipoxygenase after 5 mins by colorimetric assay				Bioorg Med Chem 22: 4151-61 (2014) Article DOI: 10.1016/j.bmc.2014.05.052 BindingDB Entry DOI: 10.7270/Q2GX4D6F
					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM86101 (2-[Cyano(3-indolyl) methylene]-3-indolone, 1) Show SMILES O=C1C(Nc2ccccc12)=C(C#N)c1c[nH]c2ccccc12 |w:2.1| Show InChI InChI=1S/C18H11N3O/c19-9-13(14-10-20-15-7-3-1-5-11(14)15)17-18(22)12-6-2-4-8-16(12)21-17/h1-8,10,20-21H/b17-13-	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.91E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description LOX inhibiting activity was measured by modifying the spectrophotometric method developed by Tappel.				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
					More data for this Ligand-Target Pair
Lipoxygenase (Glycine max)	BDBM50045848 (CHEMBL3309948) Show SMILES CN(C)c1ccc(\C=C2/CNC\C(=C/c3ccc(cc3[N+]([O-])=O)N(C)C)C2=O)c(c1)[N+]([O-])=O Show InChI InChI=1S/C23H25N5O5/c1-25(2)19-7-5-15(21(11-19)27(30)31)9-17-13-24-14-18(23(17)29)10-16-6-8-20(26(3)4)12-22(16)28(32)33/h5-12,24H,13-14H2,1-4H3/b17-9+,18-10+	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universiti Kebangsaan Malaysia Curated by ChEMBL					Assay Description Inhibition of soybean lipoxygenase after 5 mins by colorimetric assay				Bioorg Med Chem 22: 4151-61 (2014) Article DOI: 10.1016/j.bmc.2014.05.052 BindingDB Entry DOI: 10.7270/Q2GX4D6F
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86087 (Buddlejoside B, 2) Show SMILES OCC1OC(O[C@@H]2OC=C[C@H]3[C@H](O)C=C(COC(=O)c4ccc(O)c(O)c4)[C@@H]23)C(O)C(O)C1O |r,c:8,t:13| Show InChI InChI=1S/C22H26O12/c23-7-15-17(27)18(28)19(29)22(33-15)34-21-16-10(6-13(25)11(16)3-4-31-21)8-32-20(30)9-1-2-12(24)14(26)5-9/h1-6,11,13,15-19,21-29H,7-8H2/t11-,13+,15?,16+,17?,18?,19?,21-,22?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.97E+4	n/a	n/a	n/a	n/a	8.0	25
Chinese Academy of Medical Sciences					Assay Description Lipoxygenase inhibiting activity was measured by slightly modifying the spectrometric method. Lipoxygenase type I-B and linoleic acid were purchased...				J Enzyme Inhib Med Chem 23: 140-3 (2008) Article DOI: 10.1080/14756360701342532 BindingDB Entry DOI: 10.7270/Q2JH3JRC
					More data for this Ligand-Target Pair
Lipoxygenase (Glycine max)	BDBM50037297 (CHEMBL3356692) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#8]-c1ccc(cc1-[#8]-[#6]\[#6]=[#6](\[#6])-[#6])-c1cc2cc(Br)ccc2oc1=O Show InChI InChI=1S/C25H25BrO4/c1-16(2)9-11-28-23-7-5-18(15-24(23)29-12-10-17(3)4)21-14-19-13-20(26)6-8-22(19)30-25(21)27/h5-10,13-15H,11-12H2,1-4H3	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of soybean LOX assessed as reduction in conversion of sodium linoleate to 13-hydroperoxylinoleic acid by UV spectroscopy				Bioorg Med Chem 22: 6586-94 (2015) Article DOI: 10.1016/j.bmc.2014.10.008 BindingDB Entry DOI: 10.7270/Q2MK6FHF
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86092 (Buddlejoside A5, 7) Show SMILES COc1ccc(\C=C\C(=O)OC2C(O)C(C)OC(O[C@@H]3[C@@H]4O[C@]4(CO)C4C3C=CO[C@H]4OC3OC(CO)C(O)C(O)C3O)C2OC(C)=O)cc1 |r,c:29| Show InChI InChI=1S/C33H42O17/c1-14-22(38)27(47-20(37)9-6-16-4-7-17(42-3)8-5-16)28(45-15(2)36)32(44-14)48-26-18-10-11-43-30(21(18)33(13-35)29(26)50-33)49-31-25(41)24(40)23(39)19(12-34)46-31/h4-11,14,18-19,21-32,34-35,38-41H,12-13H2,1-3H3/b9-6+/t14?,18?,19?,21?,22?,23?,24?,25?,26-,27?,28?,29-,30-,31?,32?,33+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.04E+4	n/a	n/a	n/a	n/a	8.0	25
Chinese Academy of Medical Sciences					Assay Description Lipoxygenase inhibiting activity was measured by slightly modifying the spectrometric method. Lipoxygenase type I-B and linoleic acid were purchased...				J Enzyme Inhib Med Chem 23: 140-3 (2008) Article DOI: 10.1080/14756360701342532 BindingDB Entry DOI: 10.7270/Q2JH3JRC
					More data for this Ligand-Target Pair
Lipoxygenase (Glycine max)	BDBM50282833 (CHEMBL226300) Show SMILES CCN1CCN(CC1)c1nc(C)c2Nc3ccccc3Sc2n1 Show InChI InChI=1S/C17H21N5S/c1-3-21-8-10-22(11-9-21)17-18-12(2)15-16(20-17)23-14-7-5-4-6-13(14)19-15/h4-7,19H,3,8-11H2,1-2H3	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Medical University of Silesia Curated by ChEMBL					Assay Description Inhibition of soybean lipoxygenase using linoleic acid as substrate preincubated for 5 mins followed by substrate addition measuredf after 7 mins by ...				Eur J Med Chem 138: 774-806 (2017) Article DOI: 10.1016/j.ejmech.2017.07.009 BindingDB Entry DOI: 10.7270/Q26H4KZR
					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM86104 (Sulfoglucobrassicin, 4) Show SMILES OCC1OC(SC(Cc2cc3ccccc3n2S(O)(=O)=O)=NOS(O)(=O)=O)C(O)C(O)C1O |w:21.23| Show InChI InChI=1S/C16H20N2O12S3/c19-7-11-13(20)14(21)15(22)16(29-11)31-12(17-30-33(26,27)28)6-9-5-8-3-1-2-4-10(8)18(9)32(23,24)25/h1-5,11,13-16,19-22H,6-7H2,(H,23,24,25)(H,26,27,28)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.19E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description LOX inhibiting activity was measured by modifying the spectrophotometric method developed by Tappel.				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86091 (Buddlejoside A2, 6) Show SMILES COc1ccc(\C=C\C(=O)OC2C(C)OC(O[C@@H]3C=C(CO)C4C3C=CO[C@H]4OC3OC(CO)C(O)C(O)C3O)C(OC(C)=O)C2O)cc1 |r,c:25,t:18| Show InChI InChI=1S/C33H42O16/c1-15-29(48-23(37)9-6-17-4-7-19(42-3)8-5-17)28(41)30(45-16(2)36)33(44-15)46-21-12-18(13-34)24-20(21)10-11-43-31(24)49-32-27(40)26(39)25(38)22(14-35)47-32/h4-12,15,20-22,24-35,38-41H,13-14H2,1-3H3/b9-6+/t15?,20?,21-,22?,24?,25?,26?,27?,28?,29?,30?,31+,32?,33?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.19E+4	n/a	n/a	n/a	n/a	8.0	25
Chinese Academy of Medical Sciences					Assay Description Lipoxygenase inhibiting activity was measured by slightly modifying the spectrometric method. Lipoxygenase type I-B and linoleic acid were purchased...				J Enzyme Inhib Med Chem 23: 140-3 (2008) Article DOI: 10.1080/14756360701342532 BindingDB Entry DOI: 10.7270/Q2JH3JRC
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86086 (Buddlejoside A, 1) Show SMILES OCC1OC(O[C@@H]2OC=C[C@H]3[C@H](O)C=C(COC(=O)c4ccc(O)cc4)[C@@H]23)C(O)C(O)C1O |r,c:8,t:13| Show InChI InChI=1S/C22H26O11/c23-8-15-17(26)18(27)19(28)22(32-15)33-21-16-11(7-14(25)13(16)5-6-30-21)9-31-20(29)10-1-3-12(24)4-2-10/h1-7,13-19,21-28H,8-9H2/t13-,14+,15?,16+,17?,18?,19?,21-,22?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.43E+4	n/a	n/a	n/a	n/a	8.0	25
Chinese Academy of Medical Sciences					Assay Description Lipoxygenase inhibiting activity was measured by slightly modifying the spectrometric method. Lipoxygenase type I-B and linoleic acid were purchased...				J Enzyme Inhib Med Chem 23: 140-3 (2008) Article DOI: 10.1080/14756360701342532 BindingDB Entry DOI: 10.7270/Q2JH3JRC
					More data for this Ligand-Target Pair
Lipoxygenase (Glycine max)	BDBM50045847 (CHEMBL3309947) Show SMILES CN(C)c1ccc(\C=C2/COC\C(=C/c3ccc(cc3[N+]([O-])=O)N(C)C)C2=O)c(c1)[N+]([O-])=O Show InChI InChI=1S/C23H24N4O6/c1-24(2)19-7-5-15(21(11-19)26(29)30)9-17-13-33-14-18(23(17)28)10-16-6-8-20(25(3)4)12-22(16)27(31)32/h5-12H,13-14H2,1-4H3/b17-9+,18-10+	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universiti Kebangsaan Malaysia Curated by ChEMBL					Assay Description Inhibition of soybean lipoxygenase after 5 mins by colorimetric assay				Bioorg Med Chem 22: 4151-61 (2014) Article DOI: 10.1016/j.bmc.2014.05.052 BindingDB Entry DOI: 10.7270/Q2GX4D6F
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86090 (Beta-gardiol, 5) Show SMILES COC(=O)[C@@H]1C2C=C[C@@]3(O)CO[C@@H](O[C@@H]1O)C23 |r,c:6| Show InChI InChI=1S/C11H14O6/c1-15-8(12)6-5-2-3-11(14)4-16-10(7(5)11)17-9(6)13/h2-3,5-7,9-10,13-14H,4H2,1H3/t5?,6-,7?,9-,10-,11+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.73E+4	n/a	n/a	n/a	n/a	8.0	25
Chinese Academy of Medical Sciences					Assay Description Lipoxygenase inhibiting activity was measured by slightly modifying the spectrometric method. Lipoxygenase type I-B and linoleic acid were purchased...				J Enzyme Inhib Med Chem 23: 140-3 (2008) Article DOI: 10.1080/14756360701342532 BindingDB Entry DOI: 10.7270/Q2JH3JRC
					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM86105 (Isatan A, 5) Show SMILES OC1C(COC(=O)CC(O)=O)OC(Oc2c[nH]c3ccccc23)C(O)C1=O Show InChI InChI=1S/C17H17NO9/c19-12(20)5-13(21)25-7-11-14(22)15(23)16(24)17(27-11)26-10-6-18-9-4-2-1-3-8(9)10/h1-4,6,11,14,16-18,22,24H,5,7H2,(H,19,20)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.93E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description LOX inhibiting activity was measured by modifying the spectrophotometric method developed by Tappel.				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86089 (Genipin, 4) Show SMILES COC(=O)C1=CO[C@@H](O)C2C(CO)C=CC12 |r,c:13,t:4| Show InChI InChI=1S/C11H14O5/c1-15-10(13)8-5-16-11(14)9-6(4-12)2-3-7(8)9/h2-3,5-7,9,11-12,14H,4H2,1H3/t6?,7?,9?,11-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.96E+4	n/a	n/a	n/a	n/a	8.0	25
Chinese Academy of Medical Sciences					Assay Description Lipoxygenase inhibiting activity was measured by slightly modifying the spectrometric method. Lipoxygenase type I-B and linoleic acid were purchased...				J Enzyme Inhib Med Chem 23: 140-3 (2008) Article DOI: 10.1080/14756360701342532 BindingDB Entry DOI: 10.7270/Q2JH3JRC
					More data for this Ligand-Target Pair
Lipoxygenase (Glycine max)	BDBM32020 (4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...) Show SMILES CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1 Show InChI InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of soybean LOX assessed as reduction in conversion of sodium linoleate to 13-hydroperoxylinoleic acid by UV spectroscopy				Bioorg Med Chem 22: 6586-94 (2015) Article DOI: 10.1016/j.bmc.2014.10.008 BindingDB Entry DOI: 10.7270/Q2MK6FHF
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86084 (Tetraketone, 21) Show SMILES CC1(C)CC(=O)C(C(C2C(=O)CC(C)(C)CC2=O)c2ccco2)C(=O)C1 Show InChI InChI=1S/C21H26O5/c1-20(2)8-12(22)17(13(23)9-20)19(16-6-5-7-26-16)18-14(24)10-21(3,4)11-15(18)25/h5-7,17-19H,8-11H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.15E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Lipoxygenase (Glycine max)	BDBM50021467 (CHEMBL3289933) Show SMILES CCOC(OCC)c1ccc(\C=C\C(=O)C2CCc3ccccc3C2=O)cc1 Show InChI InChI=1S/C24H26O4/c1-3-27-24(28-4-2)19-12-9-17(10-13-19)11-16-22(25)21-15-14-18-7-5-6-8-20(18)23(21)26/h5-13,16,21,24H,3-4,14-15H2,1-2H3/b16-11+	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universiti Kebangsaan Malaysia Curated by ChEMBL					Assay Description Inhibition of soybean lipoxygenase after 5 mins by colorimetric assay				Bioorg Med Chem 22: 4151-61 (2014) Article DOI: 10.1016/j.bmc.2014.05.052 BindingDB Entry DOI: 10.7270/Q2GX4D6F
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86088 (Buddlejoside C, 3) Show SMILES CC(C)CC(=O)OCC1=C[C@@H](O)[C@@H]2C=CC[C@H](OC3OC(CO)C(O)C(O)C3O)[C@H]12 |r,c:13,t:8| Show InChI InChI=1S/C21H32O9/c1-10(2)6-16(24)28-9-11-7-13(23)12-4-3-5-14(17(11)12)29-21-20(27)19(26)18(25)15(8-22)30-21/h3-4,7,10,12-15,17-23,25-27H,5-6,8-9H2,1-2H3/t12-,13+,14-,15?,17+,18?,19?,20?,21?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.25E+4	n/a	n/a	n/a	n/a	8.0	25
Chinese Academy of Medical Sciences					Assay Description Lipoxygenase inhibiting activity was measured by slightly modifying the spectrometric method. Lipoxygenase type I-B and linoleic acid were purchased...				J Enzyme Inhib Med Chem 23: 140-3 (2008) Article DOI: 10.1080/14756360701342532 BindingDB Entry DOI: 10.7270/Q2JH3JRC
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86079 (Tetraketone, 14) Show SMILES CC1(C)CC(=O)C(C(C2C(=O)CC(C)(C)CC2=O)c2cccc(Br)c2)C(=O)C1 Show InChI InChI=1S/C23H27BrO4/c1-22(2)9-15(25)20(16(26)10-22)19(13-6-5-7-14(24)8-13)21-17(27)11-23(3,4)12-18(21)28/h5-8,19-21H,9-12H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.29E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM86106 (Isatan B, 6) Show SMILES OCC1OC(Oc2c[nH]c3ccccc23)C(O)C(=O)C1O Show InChI InChI=1S/C14H15NO6/c16-6-10-11(17)12(18)13(19)14(21-10)20-9-5-15-8-4-2-1-3-7(8)9/h1-5,10-11,13-17,19H,6H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.38E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description LOX inhibiting activity was measured by modifying the spectrophotometric method developed by Tappel.				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
					More data for this Ligand-Target Pair
Lipoxygenase (Glycine max)	BDBM50531970 (DISUFENTON SODIUM) Show SMILES [Na;v0+].[Na;v0+].[#6]C([#6])([#6])[#7+](\[#8-])=[#6]\c1ccc(cc1S([#8-])(=O)=O)S([#8-])(=O)=O Show InChI InChI=1S/C11H15NO7S2/c1-11(2,3)12(13)7-8-4-5-9(20(14,15)16)6-10(8)21(17,18)19/h4-7H,1-3H3,(H,14,15,16)(H,17,18,19)/p-2/b12-7-	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
IQOG, CSIC Curated by ChEMBL					Assay Description Inhibition of soybean lipoxygenase using sodium linoleate as substrate by UV-based analysis				J Med Chem 62: 2184-2201 (2019) Article DOI: 10.1021/acs.jmedchem.8b01987 BindingDB Entry DOI: 10.7270/Q2MC93HC
					More data for this Ligand-Target Pair
Lipoxygenase (Glycine max)	BDBM50025855 (CHEMBL3330910) Show SMILES COc1cc(NC(C)CCCNC(=O)NC(c2ccccc2)c2ccc(Cl)cc2)c2ncccc2c1 Show InChI InChI=1S/C29H31ClN4O2/c1-20(33-26-19-25(36-2)18-23-11-7-16-31-28(23)26)8-6-17-32-29(35)34-27(21-9-4-3-5-10-21)22-12-14-24(30)15-13-22/h3-5,7,9-16,18-20,27,33H,6,8,17H2,1-2H3,(H2,32,34,35)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Zagreb Curated by ChEMBL					Assay Description Inhibition of soybean LOX using sodium linoleate as substrate by spectrophotometry				Eur J Med Chem 86: 502-14 (2014) Article DOI: 10.1016/j.ejmech.2014.09.013 BindingDB Entry DOI: 10.7270/Q2Z89F0V
					More data for this Ligand-Target Pair

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