Compile Data Set for Download or QSAR

Found 46 hits of ic50 data for polymerid = 50006752   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572770 (3-(2-bromo-3,4-dihydroxyphenyl)-2-cyano-N-(4-pheny...) Show SMILES Oc1ccc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccccc2)c(Br)c1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM573128 (2-cyano-N-(4-(2,4-dichlorophenyl)thiazol-2-yl)-3-(...) Show SMILES Oc1ccc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccc(Cl)cc2Cl)cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM573130 (2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-(2-fluoro-4-m...) Show SMILES COc1ccc(-c2csc(NC(=O)C(Cc3ccc(O)c(O)c3)C#N)n2)c(F)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM573131 (2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-(4-(trifluoro...) Show SMILES Oc1ccc(CC(C#N)C(=O)Nc2nc(cs2)-c2cc(ccn2)C(F)(F)F)cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM573125 (2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-(5-methoxypyr...) Show SMILES COc1ccc(nc1)-c1csc(NC(=O)C(Cc2ccc(O)c(O)c2)C#N)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572574 (2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenyl-5-(p-t...) Show SMILES Cc1ccc(cc1)-c1sc(NC(=O)C(Cc2ccc(O)c(O)c2)C#N)nc1-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM573129 (2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-(3-fluoropyri...) Show SMILES Oc1ccc(CC(C#N)C(=O)Nc2nc(cs2)-c2ncccc2F)cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM573122 (2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-(5-methylpyri...) Show SMILES Cc1ccc(nc1)-c1csc(NC(=O)C(Cc2ccc(O)c(O)c2)C#N)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM573124 (2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-(4-methoxypyr...) Show SMILES COc1ccnc(c1)-c1csc(NC(=O)C(Cc2ccc(O)c(O)c2)C#N)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572983 (2-cyano-N-(4-(3,4-dichlorophenyl)thiazol-2-yl)-3-(...) Show SMILES Oc1ccc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccc(Cl)c(Cl)c2)cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572707 (2-(3,4-dihydroxybenzyl)-N1-(4-phenylthiazol-2-1 ma...) Show SMILES NC(=O)C(Cc1ccc(O)c(O)c1)C(=O)Nc1nc(cs1)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572743 (2-cyano-3-(3,5-dichloro-4-hydroxyphenyl)-N-(4-(nap...) Show SMILES Oc1c(Cl)cc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccc3ccccc3c2)cc1Cl Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572745 (2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-(thiophen-3-y...) Show SMILES Oc1ccc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccsc2)cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572746 (2-cyano-N-(5-cyclohexyl-4-phenylthiazol-2-yl)-3-(3...) Show SMILES Oc1ccc(CC(C#N)C(=O)Nc2nc(c(s2)C2CCCCC2)-c2ccccc2)cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572800 (2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-(5,6,7,8-tetr...) Show SMILES Oc1ccc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccc3CCCCc3c2)cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572801 (2-cyano-N-(4-(4-cyclohexylphenyl)thiazol-2-yl)-3-(...) Show SMILES Oc1ccc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccc(cc2)C2CCCCC2)cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572838 (3-(3-chloro-5-fluoro-4-hydroxyphenyl)-2-cyano-N-(4...) Show SMILES Oc1c(F)cc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccccc2)cc1Cl Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572839 (2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-(pyridin-2-yl...) Show SMILES Oc1ccc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccccn2)cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572844 (2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-(6-methylpyri...) Show SMILES Cc1cccc(n1)-c1csc(NC(=O)C(Cc2ccc(O)c(O)c2)C#N)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572848 (2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-(2-(trifluoro...) Show SMILES Oc1ccc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccccc2C(F)(F)F)cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572684 (N-(4-(4-(tert-butyl)phenyl)thiazol-2-yl)-2-cyano-3...) Show SMILES CC(C)(C)c1ccc(cc1)-c1csc(NC(=O)C(Cc2ccc(O)c(O)c2)C#N)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572683 (N-(4-([1,1′-biphenyl]-3-yl)thiazol-2-yl)-2-c...) Show SMILES Oc1ccc(CC(C#N)C(=O)Nc2nc(cs2)-c2cccc(c2)-c2ccccc2)cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572608 (2-cyano-3-(3,5-dichloro-4-hydroxyphenyl)-N-(4-(4-(...) Show SMILES Oc1c(Cl)cc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccc(OC(F)(F)F)cc2)cc1Cl Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572598 (2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-(4-(trifluoro...) Show SMILES Oc1ccc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccc(OC(F)(F)F)cc2)cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572573 (2-cyano-3-(3,5-dichloro-4-hydroxyphenyl)-N-(4,5-di...) Show SMILES Oc1c(Cl)cc(CC(C#N)C(=O)Nc2nc(c(s2)-c2ccccc2)-c2ccccc2)cc1Cl Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572545 (2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-(p-tolyl)thia...) Show SMILES Cc1ccc(cc1)-c1csc(NC(=O)C(Cc2ccc(O)c(O)c2)C#N)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572542 (2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-(4-(trifluoro...) Show SMILES Oc1ccc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccc(cc2)C(F)(F)F)cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572537 (2-cyano-N-(4-(4-cyanophenyl)thiazol-2-yl)-3-(3,4-d...) Show SMILES Oc1ccc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccc(cc2)C#N)cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572528 (2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenylthiazol...) Show SMILES Oc1ccc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccccc2)cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572527 (N-(4-(4-bromophenyl)thiazol-2-yl)-2-cyano-3-(3,4-d...) Show SMILES Oc1ccc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccc(Br)cc2)cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572799 (2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-(5-methylthio...) Show SMILES Cc1cc(cs1)-c1csc(NC(=O)C(Cc2ccc(O)c(O)c2)C#N)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM573132 (2-cyano-N-(4-(2,5-dichlorothiophen-3-yl)thiazol-2-...) Show SMILES Oc1ccc(CC(C#N)C(=O)Nc2nc(cs2)-c2cc(Cl)sc2Cl)cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM573127 (2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-(6-methoxypyr...) Show SMILES COc1cccc(n1)-c1csc(NC(=O)C(Cc2ccc(O)c(O)c2)C#N)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM573123 (2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-(4-isopropylp...) Show SMILES CC(C)c1ccc(cc1)-c1csc(NC(=O)C(Cc2ccc(O)c(O)c2)C#N)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM573121 (2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-(4-methylpyri...) Show SMILES Cc1ccnc(c1)-c1csc(NC(=O)C(Cc2ccc(O)c(O)c2)C#N)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM573120 (N-(4-(3-chlorophenyl)thiazol-2-yl)-2-cyano-3-(3,4-...) Show SMILES Oc1ccc(CC(C#N)C(=O)Nc2nc(cs2)-c2cccc(Cl)c2)cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM573119 (2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-(o-tolyl)thia...) Show SMILES Cc1ccccc1-c1csc(NC(=O)C(Cc2ccc(O)c(O)c2)C#N)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM50044627 (Mirin) Show SMILES Oc1ccc(cc1)-c1cc(=O)[nH]c(=S)[nH]1 Show InChI InChI=1S/C10H8N2O2S/c13-7-3-1-6(2-4-7)8-5-9(14)12-10(15)11-8/h1-5,13H,(H2,11,12,14,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Drexel University College of Medicine Curated by ChEMBL					Assay Description In vitro inhibition of purified recombinant Mre11 exonuclease activity (unknown origin)				Bioorg Med Chem Lett 24: 3006-13 (2014) Article DOI: 10.1016/j.bmcl.2014.04.088 BindingDB Entry DOI: 10.7270/Q2NV9KW7
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM573126 (2-cyano-3-(3,5-di-tert-butyl-4-hydroxyphenyl)-N-(4...) Show SMILES CC(C)(C)c1cc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccccn2)cc(c1O)C(C)(C)C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572778 (2-cyano-3-(3-cyano-4-hydroxyphenyl)-N-(4-phenylthi...) Show SMILES Oc1ccc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccccc2)cc1C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572804 (3-(3-chloro-4-hydroxy-5-methylphenyl)-2-cyano-N-(4...) Show SMILES Cc1cc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccccc2)cc(Cl)c1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572742 (3-(1H-benzo[d]imidazol-6-yl)-2-cyano-N-(4-phenylth...) Show SMILES O=C(Nc1nc(cs1)-c1ccccc1)C(Cc1ccc2nc[nH]c2c1)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572753 (2-cyano-3-(4-hydroxy-3,5-dimethylphenyl)-N-(4-phen...) Show SMILES Cc1cc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccccc2)cc(C)c1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM572771 (N-(4-(4-(tert-butyl)phenyl)thiazol-2-yl)-2-cyano-3...) Show SMILES Cc1cc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccc(cc2)C(C)(C)C)cc(C)c1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM573133 (2-cyano-3-(3,4-dihydroxyphenyl)-2-methyl-N-(4-phen...) Show SMILES CC(Cc1ccc(O)c(O)c1)(C#N)C(=O)Nc1nc(cs1)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...				Citation and Details BindingDB Entry DOI: 10.7270/Q2G73J04
					More data for this Ligand-Target Pair
Double-strand break repair protein MRE11 (Homo sapiens (Human))	BDBM50044627 (Mirin) Show SMILES Oc1ccc(cc1)-c1cc(=O)[nH]c(=S)[nH]1 Show InChI InChI=1S/C10H8N2O2S/c13-7-3-1-6(2-4-7)8-5-9(14)12-10(15)11-8/h1-5,13H,(H2,11,12,14,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Drexel University College of Medicine Curated by ChEMBL					Assay Description Inhibition of Mre11 exonuclease activity (unknown origin) in cell free extracts				Bioorg Med Chem Lett 24: 3006-13 (2014) Article DOI: 10.1016/j.bmcl.2014.04.088 BindingDB Entry DOI: 10.7270/Q2NV9KW7
					More data for this Ligand-Target Pair