Compile Data Set for Download or QSAR

Found 10 hits of ic50 data for polymerid = 50006952   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sialic acid-binding Ig-like lectin 7 (Homo sapiens (Human))	BDBM50230647 (CHEMBL4096201) Show SMILES [Na+].[H][C@]1(O[C@@](C[C@H](O)[C@H]1NC(C)=O)(OCCCn1cc(nn1)-c1ccc(cc1)-c1ccccc1)C([O-])=O)[C@H](O)[C@H](O)CNS(=O)(=O)CC |r| Show InChI InChI=1S/C30H39N5O10S.Na/c1-3-46(42,43)31-17-25(38)27(39)28-26(32-19(2)36)24(37)16-30(45-28,29(40)41)44-15-7-14-35-18-23(33-34-35)22-12-10-21(11-13-22)20-8-5-4-6-9-20;/h4-6,8-13,18,24-28,31,37-39H,3,7,14-17H2,1-2H3,(H,32,36)(H,40,41);/q;+1/p-1/t24-,25+,26+,27+,28+,30+;/m0./s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
G3-BioTec Curated by ChEMBL					Assay Description Binding affinity to human IgG1-fused Siglec-7-Fc assessed as inhibition of Siglec-7-Fc binding to RBC preincubated for 10 mins followed by RBC additi...				J Med Chem 60: 941-956 (2017) Article DOI: 10.1021/acs.jmedchem.6b01111 BindingDB Entry DOI: 10.7270/Q2HQ4253
					More data for this Ligand-Target Pair
Sialic acid-binding Ig-like lectin 7 (Homo sapiens (Human))	BDBM50230646 (CHEMBL4060254) Show SMILES [Na+].[H][C@]1(O[C@@](C[C@H](O)[C@H]1NC(C)=O)(OCCCn1cc(nn1)-c1ccc(cc1)-c1ccccc1)C([O-])=O)[C@H](O)[C@H](O)CNS(C)(=O)=O |r| Show InChI InChI=1S/C29H37N5O10S.Na/c1-18(35)31-25-23(36)15-29(28(39)40,44-27(25)26(38)24(37)16-30-45(2,41)42)43-14-6-13-34-17-22(32-33-34)21-11-9-20(10-12-21)19-7-4-3-5-8-19;/h3-5,7-12,17,23-27,30,36-38H,6,13-16H2,1-2H3,(H,31,35)(H,39,40);/q;+1/p-1/t23-,24+,25+,26+,27+,29+;/m0./s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
G3-BioTec Curated by ChEMBL					Assay Description Binding affinity to human IgG1-fused Siglec-7-Fc assessed as inhibition of Siglec-7-Fc binding to RBC preincubated for 10 mins followed by RBC additi...				J Med Chem 60: 941-956 (2017) Article DOI: 10.1021/acs.jmedchem.6b01111 BindingDB Entry DOI: 10.7270/Q2HQ4253
					More data for this Ligand-Target Pair
Sialic acid-binding Ig-like lectin 7 (Homo sapiens (Human))	BDBM50230580 (CHEMBL4094130) Show SMILES [Na+].[H][C@]1(O[C@@](C[C@H](O)[C@H]1NC(C)=O)(OCCCn1cc(nn1)-c1ccc(cc1)-c1ccccc1)C([O-])=O)[C@H](O)[C@H](O)CO |r| Show InChI InChI=1S/C28H34N4O9.Na/c1-17(34)29-24-22(35)14-28(27(38)39,41-26(24)25(37)23(36)16-33)40-13-5-12-32-15-21(30-31-32)20-10-8-19(9-11-20)18-6-3-2-4-7-18;/h2-4,6-11,15,22-26,33,35-37H,5,12-14,16H2,1H3,(H,29,34)(H,38,39);/q;+1/p-1/t22-,23+,24+,25+,26+,28+;/m0./s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
G3-BioTec Curated by ChEMBL					Assay Description Binding affinity to human IgG1-fused Siglec-7-Fc assessed as inhibition of Siglec-7-Fc binding to RBC preincubated for 10 mins followed by RBC additi...				J Med Chem 60: 941-956 (2017) Article DOI: 10.1021/acs.jmedchem.6b01111 BindingDB Entry DOI: 10.7270/Q2HQ4253
					More data for this Ligand-Target Pair
Sialic acid-binding Ig-like lectin 7 (Homo sapiens (Human))	BDBM50230647 (CHEMBL4096201) Show SMILES [Na+].[H][C@]1(O[C@@](C[C@H](O)[C@H]1NC(C)=O)(OCCCn1cc(nn1)-c1ccc(cc1)-c1ccccc1)C([O-])=O)[C@H](O)[C@H](O)CNS(=O)(=O)CC |r| Show InChI InChI=1S/C30H39N5O10S.Na/c1-3-46(42,43)31-17-25(38)27(39)28-26(32-19(2)36)24(37)16-30(45-28,29(40)41)44-15-7-14-35-18-23(33-34-35)22-12-10-21(11-13-22)20-8-5-4-6-9-20;/h4-6,8-13,18,24-28,31,37-39H,3,7,14-17H2,1-2H3,(H,32,36)(H,40,41);/q;+1/p-1/t24-,25+,26+,27+,28+,30+;/m0./s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
G3-BioTec Curated by ChEMBL					Assay Description Binding affinity to human IgG1-fused Siglec-7-Fc measured after 2.5 hrs by ELISA				J Med Chem 60: 941-956 (2017) Article DOI: 10.1021/acs.jmedchem.6b01111 BindingDB Entry DOI: 10.7270/Q2HQ4253
					More data for this Ligand-Target Pair
Sialic acid-binding Ig-like lectin 7 (Homo sapiens (Human))	BDBM50230646 (CHEMBL4060254) Show SMILES [Na+].[H][C@]1(O[C@@](C[C@H](O)[C@H]1NC(C)=O)(OCCCn1cc(nn1)-c1ccc(cc1)-c1ccccc1)C([O-])=O)[C@H](O)[C@H](O)CNS(C)(=O)=O |r| Show InChI InChI=1S/C29H37N5O10S.Na/c1-18(35)31-25-23(36)15-29(28(39)40,44-27(25)26(38)24(37)16-30-45(2,41)42)43-14-6-13-34-17-22(32-33-34)21-11-9-20(10-12-21)19-7-4-3-5-8-19;/h3-5,7-12,17,23-27,30,36-38H,6,13-16H2,1-2H3,(H,31,35)(H,39,40);/q;+1/p-1/t23-,24+,25+,26+,27+,29+;/m0./s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
G3-BioTec Curated by ChEMBL					Assay Description Binding affinity to human IgG1-fused Siglec-7-Fc measured after 2.5 hrs by ELISA				J Med Chem 60: 941-956 (2017) Article DOI: 10.1021/acs.jmedchem.6b01111 BindingDB Entry DOI: 10.7270/Q2HQ4253
					More data for this Ligand-Target Pair
Sialic acid-binding Ig-like lectin 7 (Homo sapiens (Human))	BDBM50114355 (CHEMBL3604070) Show SMILES [Na+].[H][C@]1(O[C@@](C[C@H](O)[C@H]1NC(C)=O)(OC)C([O-])=O)[C@H](O)[C@H](O)CNC(=O)C(N)=O |r| Show InChI InChI=1S/C14H23N3O10.Na/c1-5(18)17-8-6(19)3-14(26-2,13(24)25)27-10(8)9(21)7(20)4-16-12(23)11(15)22;/h6-10,19-21H,3-4H2,1-2H3,(H2,15,22)(H,16,23)(H,17,18)(H,24,25);/q;+1/p-1/t6-,7+,8+,9+,10+,14+;/m0./s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.64E+6	n/a	n/a	n/a	n/a	n/a	n/a
G3-BioTec Curated by ChEMBL					Assay Description Binding affinity to human IgG1-fused human Siglec-7-FC (Gln19 to Gly357 residues) assessed as inhibition Siglec-7-Fc binding to to RBC pre-incubated ...				Bioorg Med Chem 23: 5915-21 (2015) Article DOI: 10.1016/j.bmc.2015.06.069 BindingDB Entry DOI: 10.7270/Q2FB54RH
					More data for this Ligand-Target Pair
Sialic acid-binding Ig-like lectin 7 (Homo sapiens (Human))	BDBM50230579 (CHEMBL4077460) Show SMILES [Na+].[H][C@]1(OC(C[C@H](O)[C@H]1NC(C)=O)(OC)C([O-])=O)[C@H](O)[C@H](O)CO |r| Show InChI InChI=1S/C12H21NO9.Na/c1-5(15)13-8-6(16)3-12(21-2,11(19)20)22-10(8)9(18)7(17)4-14;/h6-10,14,16-18H,3-4H2,1-2H3,(H,13,15)(H,19,20);/q;+1/p-1/t6-,7+,8+,9+,10+,12?;/m0./s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.08E+6	n/a	n/a	n/a	n/a	n/a	n/a
G3-BioTec Curated by ChEMBL					Assay Description Binding affinity to human IgG1-fused Siglec-7-Fc assessed as inhibition of Siglec-7-Fc binding to RBC preincubated for 10 mins followed by RBC additi...				J Med Chem 60: 941-956 (2017) Article DOI: 10.1021/acs.jmedchem.6b01111 BindingDB Entry DOI: 10.7270/Q2HQ4253
					More data for this Ligand-Target Pair
Sialic acid-binding Ig-like lectin 7 (Homo sapiens (Human))	BDBM50114356 (CHEMBL3604069) Show SMILES [Na+].[H][C@]1(O[C@@](C[C@H](O)[C@H]1NC(C)=O)(OC)C([O-])=O)[C@H](O)[C@H](O)CO |r| Show InChI InChI=1S/C12H21NO9.Na/c1-5(15)13-8-6(16)3-12(21-2,11(19)20)22-10(8)9(18)7(17)4-14;/h6-10,14,16-18H,3-4H2,1-2H3,(H,13,15)(H,19,20);/q;+1/p-1/t6-,7+,8+,9+,10+,12+;/m0./s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.08E+6	n/a	n/a	n/a	n/a	n/a	n/a
G3-BioTec Curated by ChEMBL					Assay Description Binding affinity to human IgG1-fused human Siglec-7-FC (Gln19 to Gly357 residues) assessed as inhibition Siglec-7-Fc binding to to RBC pre-incubated ...				Bioorg Med Chem 23: 5915-21 (2015) Article DOI: 10.1016/j.bmc.2015.06.069 BindingDB Entry DOI: 10.7270/Q2FB54RH
					More data for this Ligand-Target Pair
Sialic acid-binding Ig-like lectin 7 (Homo sapiens (Human))	BDBM50230649 (CHEMBL3764071) Show SMILES [H][C@@]1(O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)O[C@H](CO[C@@]2(C[C@H](O)[C@@H](NC(C)=O)[C@@]([H])(O2)[C@H](O)[C@H](O)CO)C(O)=O)[C@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C23H39NO19/c1-6(27)24-11-7(28)2-23(22(37)38,43-19(11)12(30)8(29)3-25)39-5-10-13(31)14(32)17(35)21(41-10)42-18-9(4-26)40-20(36)16(34)15(18)33/h7-21,25-26,28-36H,2-5H2,1H3,(H,24,27)(H,37,38)/t7-,8+,9+,10+,11+,12+,13-,14-,15+,16+,17+,18+,19+,20+,21-,23+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.56E+7	n/a	n/a	n/a	n/a	n/a	n/a
G3-BioTec Curated by ChEMBL					Assay Description Binding affinity to human IgG1-fused Siglec-7-Fc measured after 2.5 hrs by ELISA				J Med Chem 60: 941-956 (2017) Article DOI: 10.1021/acs.jmedchem.6b01111 BindingDB Entry DOI: 10.7270/Q2HQ4253
					More data for this Ligand-Target Pair
Sialic acid-binding Ig-like lectin 7 (Homo sapiens (Human))	BDBM50230648 (CHEMBL3764379) Show SMILES [H][C@@]1(O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)O[C@H](CO)[C@H](O)[C@H](O[C@@]2(C[C@H](O)[C@@H](NC(C)=O)[C@@]([H])(O2)[C@H](O)[C@H](O)CO)C(O)=O)[C@H]1O |r| Show InChI InChI=1S/C23H39NO19/c1-6(28)24-11-7(29)2-23(22(37)38,42-18(11)12(31)8(30)3-25)43-19-13(32)9(4-26)40-21(16(19)35)41-17-10(5-27)39-20(36)15(34)14(17)33/h7-21,25-27,29-36H,2-5H2,1H3,(H,24,28)(H,37,38)/t7-,8+,9+,10+,11+,12+,13-,14+,15+,16+,17+,18+,19-,20+,21-,23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.69E+7	n/a	n/a	n/a	n/a	n/a	n/a
G3-BioTec Curated by ChEMBL					Assay Description Binding affinity to human IgG1-fused Siglec-7-Fc measured after 2.5 hrs by ELISA				J Med Chem 60: 941-956 (2017) Article DOI: 10.1021/acs.jmedchem.6b01111 BindingDB Entry DOI: 10.7270/Q2HQ4253
					More data for this Ligand-Target Pair