Compile Data Set for Download or QSAR

Found 158 hits of ic50 data for polymerid = 6144,6144   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stromelysin-2 (Homo sapiens (Human))	BDBM50203953 (CHEMBL3932562) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1cccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)c1)C(=O)NO |r| Show InChI InChI=1S/C27H27N5O6S/c1-16(2)23(26(34)31-36)32-39(37,38)20-12-10-18(11-13-20)19-7-5-6-17(14-19)15-28-27(35)24-29-22-9-4-3-8-21(22)25(33)30-24/h3-14,16,23,32,36H,15H2,1-2H3,(H,28,35)(H,31,34)(H,29,30,33)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of recombinant human AMPA-activated MMP10 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric method				Bioorg Med Chem 24: 6149-6165 (2016) Article DOI: 10.1016/j.bmc.2016.09.009 BindingDB Entry DOI: 10.7270/Q2H1341V
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50204002 (CHEMBL3889936) Show SMILES CC(C)C(CS(=O)(=O)c1ccc(cc1)-c1cccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)c1)N(O)C=O Show InChI InChI=1S/C28H28N4O6S/c1-18(2)25(32(36)17-33)16-39(37,38)22-12-10-20(11-13-22)21-7-5-6-19(14-21)15-29-28(35)26-30-24-9-4-3-8-23(24)27(34)31-26/h3-14,17-18,25,36H,15-16H2,1-2H3,(H,29,35)(H,30,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.350	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of recombinant human AMPA-activated MMP10 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric method				Bioorg Med Chem 24: 6149-6165 (2016) Article DOI: 10.1016/j.bmc.2016.09.009 BindingDB Entry DOI: 10.7270/Q2H1341V
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM11863 (4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...) Show SMILES ONC(=O)C1(CS(=O)(=O)c2ccc(Oc3ccc(Cl)cc3)cc2)CCOCC1 Show InChI InChI=1S/C19H20ClNO6S/c20-14-1-3-15(4-2-14)27-16-5-7-17(8-6-16)28(24,25)13-19(18(22)21-23)9-11-26-12-10-19/h1-8,23H,9-13H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.540	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP10 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate after 40 mins by spectrofluorimetry				J Med Chem 57: 8886-902 (2014) Article DOI: 10.1021/jm500981k BindingDB Entry DOI: 10.7270/Q28P628P
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM11863 (4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...) Show SMILES ONC(=O)C1(CS(=O)(=O)c2ccc(Oc3ccc(Cl)cc3)cc2)CCOCC1 Show InChI InChI=1S/C19H20ClNO6S/c20-14-1-3-15(4-2-14)27-16-5-7-17(8-6-16)28(24,25)13-19(18(22)21-23)9-11-26-12-10-19/h1-8,23H,9-13H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.540	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP10 using fluorescence peptide Cy3-PLGLK(Cy5Q)AR-NH2 substrate by fluorescence assay				Bioorg Med Chem 22: 5487-505 (2014) Article DOI: 10.1016/j.bmc.2014.07.025 BindingDB Entry DOI: 10.7270/Q27S7QBJ
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM11863 (4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...) Show SMILES ONC(=O)C1(CS(=O)(=O)c2ccc(Oc3ccc(Cl)cc3)cc2)CCOCC1 Show InChI InChI=1S/C19H20ClNO6S/c20-14-1-3-15(4-2-14)27-16-5-7-17(8-6-16)28(24,25)13-19(18(22)21-23)9-11-26-12-10-19/h1-8,23H,9-13H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.540	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of APMA-activated recombinant human MMP-10 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...				J Med Chem 60: 608-626 (2017) Article DOI: 10.1021/acs.jmedchem.6b01007 BindingDB Entry DOI: 10.7270/Q2W95CF2
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM11863 (4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...) Show SMILES ONC(=O)C1(CS(=O)(=O)c2ccc(Oc3ccc(Cl)cc3)cc2)CCOCC1 Show InChI InChI=1S/C19H20ClNO6S/c20-14-1-3-15(4-2-14)27-16-5-7-17(8-6-16)28(24,25)13-19(18(22)21-23)9-11-26-12-10-19/h1-8,23H,9-13H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.540	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of recombinant human AMPA-activated MMP10 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric method				Bioorg Med Chem 24: 6149-6165 (2016) Article DOI: 10.1016/j.bmc.2016.09.009 BindingDB Entry DOI: 10.7270/Q2H1341V
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50203956 (CHEMBL3971135) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1cccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)c1)C(O)=O |r| Show InChI InChI=1S/C27H26N4O6S/c1-16(2)23(27(34)35)31-38(36,37)20-12-10-18(11-13-20)19-7-5-6-17(14-19)15-28-26(33)24-29-22-9-4-3-8-21(22)25(32)30-24/h3-14,16,23,31H,15H2,1-2H3,(H,28,33)(H,34,35)(H,29,30,32)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of recombinant human AMPA-activated MMP10 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric method				Bioorg Med Chem 24: 6149-6165 (2016) Article DOI: 10.1016/j.bmc.2016.09.009 BindingDB Entry DOI: 10.7270/Q2H1341V
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50203961 (CHEMBL3958969) Show SMILES ONC(=O)C1CCCCN1S(=O)(=O)CCCOc1cccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)c1 Show InChI InChI=1S/C25H29N5O7S/c31-23-19-9-1-2-10-20(19)27-22(28-23)25(33)26-16-17-7-5-8-18(15-17)37-13-6-14-38(35,36)30-12-4-3-11-21(30)24(32)29-34/h1-2,5,7-10,15,21,34H,3-4,6,11-14,16H2,(H,26,33)(H,29,32)(H,27,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of recombinant human AMPA-activated MMP10 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric method				Bioorg Med Chem 24: 6149-6165 (2016) Article DOI: 10.1016/j.bmc.2016.09.009 BindingDB Entry DOI: 10.7270/Q2H1341V
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50078191 (CHEMBL3417750) Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(Oc2ccc(OC(F)F)cc2)cc1 Show InChI InChI=1S/C23H26F2N2O6S/c24-21(25)33-18-3-1-16(2-4-18)32-17-5-7-19(8-6-17)34(30,31)23(20(28)27-29)10-9-22(15-23)11-13-26-14-12-22/h1-8,21,26,29H,9-15H2,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University of Navarra Curated by ChEMBL					Assay Description Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay				J Med Chem 58: 2465-88 (2015) Article DOI: 10.1021/jm501940y BindingDB Entry DOI: 10.7270/Q28C9XXK
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50078196 (CHEMBL3417745) Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C23H25F3N2O6S/c24-23(25,26)34-18-3-1-16(2-4-18)33-17-5-7-19(8-6-17)35(31,32)22(20(29)28-30)10-9-21(15-22)11-13-27-14-12-21/h1-8,27,30H,9-15H2,(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Navarra Curated by ChEMBL					Assay Description Inhibition of MMP10 (unknown origin) using fluorescently-labeled substrate measured every min for 1 min				ACS Med Chem Lett 9: 428-433 (2018) Article DOI: 10.1021/acsmedchemlett.7b00549 BindingDB Entry DOI: 10.7270/Q2BK1FXF
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50078196 (CHEMBL3417745) Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C23H25F3N2O6S/c24-23(25,26)34-18-3-1-16(2-4-18)33-17-5-7-19(8-6-17)35(31,32)22(20(29)28-30)10-9-21(15-22)11-13-27-14-12-21/h1-8,27,30H,9-15H2,(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of Navarra Curated by ChEMBL					Assay Description Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay				J Med Chem 58: 2465-88 (2015) Article DOI: 10.1021/jm501940y BindingDB Entry DOI: 10.7270/Q28C9XXK
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50203959 (CHEMBL3955430) Show SMILES O=C(Cc1n[nH]c(=O)[nH]1)N1CCN(CC1)c1cccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)c1 Show InChI InChI=1S/C24H24N8O4/c33-20(13-19-27-24(36)30-29-19)32-10-8-31(9-11-32)16-5-3-4-15(12-16)14-25-23(35)21-26-18-7-2-1-6-17(18)22(34)28-21/h1-7,12H,8-11,13-14H2,(H,25,35)(H,26,28,34)(H2,27,29,30,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of recombinant human AMPA-activated MMP10 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric method				Bioorg Med Chem 24: 6149-6165 (2016) Article DOI: 10.1016/j.bmc.2016.09.009 BindingDB Entry DOI: 10.7270/Q2H1341V
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50078193 (CHEMBL3417748) Show SMILES Cc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C23H28N2O5S/c1-17-2-4-18(5-3-17)30-19-6-8-20(9-7-19)31(28,29)23(21(26)25-27)11-10-22(16-23)12-14-24-15-13-22/h2-9,24,27H,10-16H2,1H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
University of Navarra Curated by ChEMBL					Assay Description Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay				J Med Chem 58: 2465-88 (2015) Article DOI: 10.1021/jm501940y BindingDB Entry DOI: 10.7270/Q28C9XXK
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50592903 (CHEMBL5199189) Show SMILES COc1ccc(cc1)-c1cn(nn1)-c1ccc(cc1)S(=O)(=O)C1(CCOCC1)C(=O)NO Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01855 BindingDB Entry DOI: 10.7270/Q2GB281X
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50078175 (CHEMBL3417766) Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCN(CC3)C(C)=O)C(=O)NO)cc1 Show InChI InChI=1S/C25H30N2O7S/c1-18(28)27-15-13-24(14-16-27)11-12-25(17-24,23(29)26-30)35(31,32)22-9-7-21(8-10-22)34-20-5-3-19(33-2)4-6-20/h3-10,30H,11-17H2,1-2H3,(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
University of Navarra Curated by ChEMBL					Assay Description Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay				J Med Chem 58: 2465-88 (2015) Article DOI: 10.1021/jm501940y BindingDB Entry DOI: 10.7270/Q28C9XXK
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50203962 (CHEMBL3917494) Show SMILES CC(C)C(CS(=O)(=O)c1ccc(cc1)-c1cccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)c1)N(O)C(N)=O Show InChI InChI=1S/C28H29N5O6S/c1-17(2)24(33(37)28(29)36)16-40(38,39)21-12-10-19(11-13-21)20-7-5-6-18(14-20)15-30-27(35)25-31-23-9-4-3-8-22(23)26(34)32-25/h3-14,17,24,37H,15-16H2,1-2H3,(H2,29,36)(H,30,35)(H,31,32,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of recombinant human AMPA-activated MMP10 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric method				Bioorg Med Chem 24: 6149-6165 (2016) Article DOI: 10.1016/j.bmc.2016.09.009 BindingDB Entry DOI: 10.7270/Q2H1341V
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50204009 (CHEMBL3927817) Show SMILES O=C(Cc1cc(=O)[nH][nH]1)N1CCN(CC1)c1cccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)c1 Show InChI InChI=1S/C25H25N7O4/c33-21-13-17(29-30-21)14-22(34)32-10-8-31(9-11-32)18-5-3-4-16(12-18)15-26-25(36)23-27-20-7-2-1-6-19(20)24(35)28-23/h1-7,12-13H,8-11,14-15H2,(H,26,36)(H,27,28,35)(H2,29,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of recombinant human AMPA-activated MMP10 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric method				Bioorg Med Chem 24: 6149-6165 (2016) Article DOI: 10.1016/j.bmc.2016.09.009 BindingDB Entry DOI: 10.7270/Q2H1341V
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50203963 (CHEMBL3907881) Show SMILES O=C(CC1NC(=O)NC1=O)N1CCN(CC1)c1cccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)c1 Show InChI InChI=1S/C25H25N7O5/c33-20(13-19-23(35)30-25(37)28-19)32-10-8-31(9-11-32)16-5-3-4-15(12-16)14-26-24(36)21-27-18-7-2-1-6-17(18)22(34)29-21/h1-7,12,19H,8-11,13-14H2,(H,26,36)(H,27,29,34)(H2,28,30,35,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of recombinant human AMPA-activated MMP10 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric method				Bioorg Med Chem 24: 6149-6165 (2016) Article DOI: 10.1016/j.bmc.2016.09.009 BindingDB Entry DOI: 10.7270/Q2H1341V
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50078171 (CHEMBL3417770) Show SMILES CNC(=O)c1ccc(Oc2ccc(cc2)S(=O)(=O)[C@@]2(CCC3(C2)CCNCC3)C(=O)NO)cc1 |r| Show InChI InChI=1S/C24H29N3O6S/c1-25-21(28)17-2-4-18(5-3-17)33-19-6-8-20(9-7-19)34(31,32)24(22(29)27-30)11-10-23(16-24)12-14-26-15-13-23/h2-9,26,30H,10-16H2,1H3,(H,25,28)(H,27,29)/t24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of Navarra Curated by ChEMBL					Assay Description Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay				J Med Chem 58: 2465-88 (2015) Article DOI: 10.1021/jm501940y BindingDB Entry DOI: 10.7270/Q28C9XXK
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50078199 (CHEMBL3417742) Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C23H28N2O6S/c1-30-17-2-4-18(5-3-17)31-19-6-8-20(9-7-19)32(28,29)23(21(26)25-27)11-10-22(16-23)12-14-24-15-13-22/h2-9,24,27H,10-16H2,1H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of Navarra Curated by ChEMBL					Assay Description Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay				J Med Chem 58: 2465-88 (2015) Article DOI: 10.1021/jm501940y BindingDB Entry DOI: 10.7270/Q28C9XXK
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50078189 (CHEMBL3417752) Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(Oc2ccc(cc2)C(=O)N2CCCC2)cc1 Show InChI InChI=1S/C27H33N3O6S/c31-24(30-17-1-2-18-30)20-3-5-21(6-4-20)36-22-7-9-23(10-8-22)37(34,35)27(25(32)29-33)12-11-26(19-27)13-15-28-16-14-26/h3-10,28,33H,1-2,11-19H2,(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
University of Navarra Curated by ChEMBL					Assay Description Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay				J Med Chem 58: 2465-88 (2015) Article DOI: 10.1021/jm501940y BindingDB Entry DOI: 10.7270/Q28C9XXK
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50078186 (CHEMBL3417755) Show SMILES COc1cccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)c1 Show InChI InChI=1S/C23H28N2O6S/c1-30-18-3-2-4-19(15-18)31-17-5-7-20(8-6-17)32(28,29)23(21(26)25-27)10-9-22(16-23)11-13-24-14-12-22/h2-8,15,24,27H,9-14,16H2,1H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
University of Navarra Curated by ChEMBL					Assay Description Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay				J Med Chem 58: 2465-88 (2015) Article DOI: 10.1021/jm501940y BindingDB Entry DOI: 10.7270/Q28C9XXK
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50078176 (CHEMBL3417765) Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCN(CCC(F)(F)F)CC3)C(=O)NO)cc1 Show InChI InChI=1S/C26H31F3N2O6S/c1-36-19-2-4-20(5-3-19)37-21-6-8-22(9-7-21)38(34,35)25(23(32)30-33)11-10-24(18-25)12-15-31(16-13-24)17-14-26(27,28)29/h2-9,33H,10-18H2,1H3,(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
University of Navarra Curated by ChEMBL					Assay Description Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay				J Med Chem 58: 2465-88 (2015) Article DOI: 10.1021/jm501940y BindingDB Entry DOI: 10.7270/Q28C9XXK
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50078177 (CHEMBL3417764) Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCN(C)CC3)C(=O)NO)cc1 Show InChI InChI=1S/C24H30N2O6S/c1-26-15-13-23(14-16-26)11-12-24(17-23,22(27)25-28)33(29,30)21-9-7-20(8-10-21)32-19-5-3-18(31-2)4-6-19/h3-10,28H,11-17H2,1-2H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of Navarra Curated by ChEMBL					Assay Description Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay				J Med Chem 58: 2465-88 (2015) Article DOI: 10.1021/jm501940y BindingDB Entry DOI: 10.7270/Q28C9XXK
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50078172 (CHEMBL3417769) Show SMILES CNC(=O)c1ccc(Oc2ccc(cc2)S(=O)(=O)[C@]2(CCC3(C2)CCNCC3)C(=O)NO)cc1 |r| Show InChI InChI=1S/C24H29N3O6S/c1-25-21(28)17-2-4-18(5-3-17)33-19-6-8-20(9-7-19)34(31,32)24(22(29)27-30)11-10-23(16-24)12-14-26-15-13-23/h2-9,26,30H,10-16H2,1H3,(H,25,28)(H,27,29)/t24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of Navarra Curated by ChEMBL					Assay Description Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay				J Med Chem 58: 2465-88 (2015) Article DOI: 10.1021/jm501940y BindingDB Entry DOI: 10.7270/Q28C9XXK
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50078174 (CHEMBL3417767) Show SMILES COc1ccc(cc1)C(=O)Oc1ccc(cc1)S(=O)(=O)C1(CCC2(C1)CCNCC2)C(=O)NO Show InChI InChI=1S/C24H28N2O7S/c1-32-18-4-2-17(3-5-18)21(27)33-19-6-8-20(9-7-19)34(30,31)24(22(28)26-29)11-10-23(16-24)12-14-25-15-13-23/h2-9,25,29H,10-16H2,1H3,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of Navarra Curated by ChEMBL					Assay Description Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay				J Med Chem 58: 2465-88 (2015) Article DOI: 10.1021/jm501940y BindingDB Entry DOI: 10.7270/Q28C9XXK
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50078190 (CHEMBL3417751) Show SMILES CNC(=O)c1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C24H29N3O6S/c1-25-21(28)17-2-4-18(5-3-17)33-19-6-8-20(9-7-19)34(31,32)24(22(29)27-30)11-10-23(16-24)12-14-26-15-13-23/h2-9,26,30H,10-16H2,1H3,(H,25,28)(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
University of Navarra Curated by ChEMBL					Assay Description Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay				J Med Chem 58: 2465-88 (2015) Article DOI: 10.1021/jm501940y BindingDB Entry DOI: 10.7270/Q28C9XXK
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50233892 (CHEMBL4068241) Show SMILES Cc1csc2nc([nH]c(=O)c12)C(=O)NCc1cccc(OCCOc2nc[nH]n2)c1 Show InChI InChI=1S/C19H18N6O4S/c1-11-9-30-18-14(11)16(26)23-15(24-18)17(27)20-8-12-3-2-4-13(7-12)28-5-6-29-19-21-10-22-25-19/h2-4,7,9-10H,5-6,8H2,1H3,(H,20,27)(H,21,22,25)(H,23,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of APMA-activated recombinant human MMP-10 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...				J Med Chem 60: 608-626 (2017) Article DOI: 10.1021/acs.jmedchem.6b01007 BindingDB Entry DOI: 10.7270/Q2W95CF2
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50250161 (CHEMBL4071820) Show SMILES COc1cc(CNC(=O)C#Cc2cn(Cc3ccc(cc3)-c3cnco3)c(=O)[nH]c2=O)ccc1F Show InChI InChI=1S/C25H19FN4O5/c1-34-21-10-17(4-8-20(21)26)11-28-23(31)9-7-19-14-30(25(33)29-24(19)32)13-16-2-5-18(6-3-16)22-12-27-15-35-22/h2-6,8,10,12,14-15H,11,13H2,1H3,(H,28,31)(H,29,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemistry and Biotechnology, Center for Organic and Medicinal Chemistry, ZHAW Zurich University of Applied Sciences , Einsiedlerstrasse 31, 8820 Wädenswil, Switzerland. Curated by ChEMBL					Assay Description Inhibition of MMP10 (unknown origin) assessed using (5-FAM/QX) FRET peptide as substrate by fluorescence assay				J Med Chem 60: 9585-9598 (2017) Article DOI: 10.1021/acs.jmedchem.7b01001 BindingDB Entry DOI: 10.7270/Q280551H
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50250161 (CHEMBL4071820) Show SMILES COc1cc(CNC(=O)C#Cc2cn(Cc3ccc(cc3)-c3cnco3)c(=O)[nH]c2=O)ccc1F Show InChI InChI=1S/C25H19FN4O5/c1-34-21-10-17(4-8-20(21)26)11-28-23(31)9-7-19-14-30(25(33)29-24(19)32)13-16-2-5-18(6-3-16)22-12-27-15-35-22/h2-6,8,10,12,14-15H,11,13H2,1H3,(H,28,31)(H,29,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemistry and Biotechnology, Center for Organic and Medicinal Chemistry, ZHAW Zurich University of Applied Sciences , Einsiedlerstrasse 31, 8820 Wädenswil, Switzerland. Curated by ChEMBL					Assay Description Inhibition of MMP10 (unknown origin) assessed using (5-FAM/QX) FRET peptide as substrate by fluorescence assay				J Med Chem 60: 9585-9598 (2017) Article DOI: 10.1021/acs.jmedchem.7b01001 BindingDB Entry DOI: 10.7270/Q280551H
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50078195 (CHEMBL3417746) Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(OCc2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C24H27F3N2O6S/c25-24(26,27)35-19-3-1-17(2-4-19)15-34-18-5-7-20(8-6-18)36(32,33)23(21(30)29-31)10-9-22(16-23)11-13-28-14-12-22/h1-8,28,31H,9-16H2,(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
University of Navarra Curated by ChEMBL					Assay Description Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay				J Med Chem 58: 2465-88 (2015) Article DOI: 10.1021/jm501940y BindingDB Entry DOI: 10.7270/Q28C9XXK
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50203957 (CHEMBL3900916) Show SMILES Clc1cccc(c1)-c1csc2nc([nH]c(=O)c12)C(=O)NCc1cccc(c1)-c1ccc(CS(=O)(=O)Cc2n[nH]c(=O)[nH]2)cc1 Show InChI InChI=1S/C30H23ClN6O5S2/c31-22-6-2-5-21(12-22)23-14-43-29-25(23)27(38)34-26(35-29)28(39)32-13-18-3-1-4-20(11-18)19-9-7-17(8-10-19)15-44(41,42)16-24-33-30(40)37-36-24/h1-12,14H,13,15-16H2,(H,32,39)(H,34,35,38)(H2,33,36,37,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of recombinant human AMPA-activated MMP10 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric method				Bioorg Med Chem 24: 6149-6165 (2016) Article DOI: 10.1016/j.bmc.2016.09.009 BindingDB Entry DOI: 10.7270/Q2H1341V
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50078192 (CHEMBL3417749) Show SMILES CC(C)(C)c1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C26H34N2O5S/c1-24(2,3)19-4-6-20(7-5-19)33-21-8-10-22(11-9-21)34(31,32)26(23(29)28-30)13-12-25(18-26)14-16-27-17-15-25/h4-11,27,30H,12-18H2,1-3H3,(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
University of Navarra Curated by ChEMBL					Assay Description Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay				J Med Chem 58: 2465-88 (2015) Article DOI: 10.1021/jm501940y BindingDB Entry DOI: 10.7270/Q28C9XXK
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50592901 (CHEMBL5176328) Show SMILES CN(C)c1ccc(cc1)-c1cn(nn1)-c1ccc(cc1)S(=O)(=O)C1(CCOCC1)C(=O)NO Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01855 BindingDB Entry DOI: 10.7270/Q2GB281X
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50592902 (CHEMBL5198463) Show SMILES ONC(=O)C1(CCOCC1)S(=O)(=O)c1ccc(cc1)-n1cc(nn1)-c1ccc(cc1)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01855 BindingDB Entry DOI: 10.7270/Q2GB281X
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50078181 (CHEMBL3417760) Show SMILES ONC(=O)C1(CCC2(C1)CCNCC2)S(=O)(=O)c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C23H28N2O5S/c26-21(25-27)23(11-10-22(17-23)12-14-24-15-13-22)31(28,29)20-8-6-19(7-9-20)30-16-18-4-2-1-3-5-18/h1-9,24,27H,10-17H2,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
University of Navarra Curated by ChEMBL					Assay Description Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay				J Med Chem 58: 2465-88 (2015) Article DOI: 10.1021/jm501940y BindingDB Entry DOI: 10.7270/Q28C9XXK
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50233877 (CHEMBL4068176) Show SMILES Fc1cccc(c1)-c1csc2nc([nH]c(=O)c12)C(=O)NCc1cccc(OCCOc2nc[nH]n2)c1 Show InChI InChI=1S/C24H19FN6O4S/c25-16-5-2-4-15(10-16)18-12-36-23-19(18)21(32)29-20(30-23)22(33)26-11-14-3-1-6-17(9-14)34-7-8-35-24-27-13-28-31-24/h1-6,9-10,12-13H,7-8,11H2,(H,26,33)(H,27,28,31)(H,29,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of APMA-activated recombinant human MMP-10 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...				J Med Chem 60: 608-626 (2017) Article DOI: 10.1021/acs.jmedchem.6b01007 BindingDB Entry DOI: 10.7270/Q2W95CF2
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50078187 (CHEMBL3417754) Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cn1 Show InChI InChI=1S/C22H27N3O6S/c1-30-19-7-4-17(14-24-19)31-16-2-5-18(6-3-16)32(28,29)22(20(26)25-27)9-8-21(15-22)10-12-23-13-11-21/h2-7,14,23,27H,8-13,15H2,1H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
University of Navarra Curated by ChEMBL					Assay Description Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay				J Med Chem 58: 2465-88 (2015) Article DOI: 10.1021/jm501940y BindingDB Entry DOI: 10.7270/Q28C9XXK
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50204005 (CHEMBL3907007) Show SMILES CC(C)C(CS(=O)(=O)c1ccc(cc1)-c1cccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)c1)N(O)C(C)=O Show InChI InChI=1S/C29H30N4O6S/c1-18(2)26(33(37)19(3)34)17-40(38,39)23-13-11-21(12-14-23)22-8-6-7-20(15-22)16-30-29(36)27-31-25-10-5-4-9-24(25)28(35)32-27/h4-15,18,26,37H,16-17H2,1-3H3,(H,30,36)(H,31,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of recombinant human AMPA-activated MMP10 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric method				Bioorg Med Chem 24: 6149-6165 (2016) Article DOI: 10.1016/j.bmc.2016.09.009 BindingDB Entry DOI: 10.7270/Q2H1341V
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50078180 (CHEMBL3417761) Show SMILES CNC(=O)c1ccc(COc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)cc1 Show InChI InChI=1S/C25H31N3O6S/c1-26-22(29)19-4-2-18(3-5-19)16-34-20-6-8-21(9-7-20)35(32,33)25(23(30)28-31)11-10-24(17-25)12-14-27-15-13-24/h2-9,27,31H,10-17H2,1H3,(H,26,29)(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
University of Navarra Curated by ChEMBL					Assay Description Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay				J Med Chem 58: 2465-88 (2015) Article DOI: 10.1021/jm501940y BindingDB Entry DOI: 10.7270/Q28C9XXK
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50078200 (CHEMBL3417741) Show SMILES COc1ccc(cc1)S(=O)(=O)C1(CCC2(C1)CCNCC2)C(=O)NO Show InChI InChI=1S/C17H24N2O5S/c1-24-13-2-4-14(5-3-13)25(22,23)17(15(20)19-21)7-6-16(12-17)8-10-18-11-9-16/h2-5,18,21H,6-12H2,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
University of Navarra Curated by ChEMBL					Assay Description Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay				J Med Chem 58: 2465-88 (2015) Article DOI: 10.1021/jm501940y BindingDB Entry DOI: 10.7270/Q28C9XXK
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50078184 (CHEMBL3417757) Show SMILES CNC(=O)c1cccc(Oc2ccc(cc2)S(=O)(=O)C2(CCC3(C2)CCNCC3)C(=O)NO)c1 Show InChI InChI=1S/C24H29N3O6S/c1-25-21(28)17-3-2-4-19(15-17)33-18-5-7-20(8-6-18)34(31,32)24(22(29)27-30)10-9-23(16-24)11-13-26-14-12-23/h2-8,15,26,30H,9-14,16H2,1H3,(H,25,28)(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
University of Navarra Curated by ChEMBL					Assay Description Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay				J Med Chem 58: 2465-88 (2015) Article DOI: 10.1021/jm501940y BindingDB Entry DOI: 10.7270/Q28C9XXK
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50078173 (CHEMBL3417768) Show SMILES CNC(=O)c1ccc(cc1)C(=O)Oc1ccc(cc1)S(=O)(=O)C1(CCC2(C1)CCNCC2)C(=O)NO Show InChI InChI=1S/C25H29N3O7S/c1-26-21(29)17-2-4-18(5-3-17)22(30)35-19-6-8-20(9-7-19)36(33,34)25(23(31)28-32)11-10-24(16-25)12-14-27-15-13-24/h2-9,27,32H,10-16H2,1H3,(H,26,29)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	103	n/a	n/a	n/a	n/a	n/a	n/a
University of Navarra Curated by ChEMBL					Assay Description Inhibition of MMP-10 (unknown origin) measured every minute for 1 hr by fluorescence assay				J Med Chem 58: 2465-88 (2015) Article DOI: 10.1021/jm501940y BindingDB Entry DOI: 10.7270/Q28C9XXK
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50250175 (CHEMBL4080183) Show SMILES COc1cc(CNC(=O)C#Cc2cn(Cc3ccc(cc3)S(=O)(=O)NC3CC3)c(=O)[nH]c2=O)ccc1F Show InChI InChI=1S/C25H23FN4O6S/c1-36-22-12-17(4-10-21(22)26)13-27-23(31)11-5-18-15-30(25(33)28-24(18)32)14-16-2-8-20(9-3-16)37(34,35)29-19-6-7-19/h2-4,8-10,12,15,19,29H,6-7,13-14H2,1H3,(H,27,31)(H,28,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemistry and Biotechnology, Center for Organic and Medicinal Chemistry, ZHAW Zurich University of Applied Sciences , Einsiedlerstrasse 31, 8820 Wädenswil, Switzerland. Curated by ChEMBL					Assay Description Inhibition of MMP10 (unknown origin) assessed using (5-FAM/QX) FRET peptide as substrate by fluorescence assay				J Med Chem 60: 9585-9598 (2017) Article DOI: 10.1021/acs.jmedchem.7b01001 BindingDB Entry DOI: 10.7270/Q280551H
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50250175 (CHEMBL4080183) Show SMILES COc1cc(CNC(=O)C#Cc2cn(Cc3ccc(cc3)S(=O)(=O)NC3CC3)c(=O)[nH]c2=O)ccc1F Show InChI InChI=1S/C25H23FN4O6S/c1-36-22-12-17(4-10-21(22)26)13-27-23(31)11-5-18-15-30(25(33)28-24(18)32)14-16-2-8-20(9-3-16)37(34,35)29-19-6-7-19/h2-4,8-10,12,15,19,29H,6-7,13-14H2,1H3,(H,27,31)(H,28,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemistry and Biotechnology, Center for Organic and Medicinal Chemistry, ZHAW Zurich University of Applied Sciences , Einsiedlerstrasse 31, 8820 Wädenswil, Switzerland. Curated by ChEMBL					Assay Description Inhibition of MMP10 (unknown origin) assessed using (5-FAM/QX) FRET peptide as substrate by fluorescence assay				J Med Chem 60: 9585-9598 (2017) Article DOI: 10.1021/acs.jmedchem.7b01001 BindingDB Entry DOI: 10.7270/Q280551H
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50250162 (CHEMBL4098213) Show SMILES COc1cc(CNC(=O)C#Cc2cn(Cc3ccc(cc3)S(=O)(=O)NC(C)(C)C)c(=O)[nH]c2=O)ccc1F Show InChI InChI=1S/C26H27FN4O6S/c1-26(2,3)30-38(35,36)20-9-5-17(6-10-20)15-31-16-19(24(33)29-25(31)34)8-12-23(32)28-14-18-7-11-21(27)22(13-18)37-4/h5-7,9-11,13,16,30H,14-15H2,1-4H3,(H,28,32)(H,29,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	131	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemistry and Biotechnology, Center for Organic and Medicinal Chemistry, ZHAW Zurich University of Applied Sciences , Einsiedlerstrasse 31, 8820 Wädenswil, Switzerland. Curated by ChEMBL					Assay Description Inhibition of MMP10 (unknown origin) assessed using (5-FAM/QX) FRET peptide as substrate by fluorescence assay				J Med Chem 60: 9585-9598 (2017) Article DOI: 10.1021/acs.jmedchem.7b01001 BindingDB Entry DOI: 10.7270/Q280551H
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50233900 (CHEMBL4083954) Show SMILES O=C(NCc1cccc(OCCSc2nc[nH]n2)c1)c1nc2ccccc2c(=O)[nH]1 Show InChI InChI=1S/C20H18N6O3S/c27-18-15-6-1-2-7-16(15)24-17(25-18)19(28)21-11-13-4-3-5-14(10-13)29-8-9-30-20-22-12-23-26-20/h1-7,10,12H,8-9,11H2,(H,21,28)(H,22,23,26)(H,24,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of APMA-activated recombinant human MMP-10 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...				J Med Chem 60: 608-626 (2017) Article DOI: 10.1021/acs.jmedchem.6b01007 BindingDB Entry DOI: 10.7270/Q2W95CF2
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50233888 (CHEMBL4092215) Show SMILES Cc1csc2nc([nH]c(=O)c12)C(=O)NCc1cccc(OCCCSc2nc[nH]n2)c1 Show InChI InChI=1S/C20H20N6O3S2/c1-12-10-31-19-15(12)17(27)24-16(25-19)18(28)21-9-13-4-2-5-14(8-13)29-6-3-7-30-20-22-11-23-26-20/h2,4-5,8,10-11H,3,6-7,9H2,1H3,(H,21,28)(H,22,23,26)(H,24,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of APMA-activated recombinant human MMP-10 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...				J Med Chem 60: 608-626 (2017) Article DOI: 10.1021/acs.jmedchem.6b01007 BindingDB Entry DOI: 10.7270/Q2W95CF2
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50250162 (CHEMBL4098213) Show SMILES COc1cc(CNC(=O)C#Cc2cn(Cc3ccc(cc3)S(=O)(=O)NC(C)(C)C)c(=O)[nH]c2=O)ccc1F Show InChI InChI=1S/C26H27FN4O6S/c1-26(2,3)30-38(35,36)20-9-5-17(6-10-20)15-31-16-19(24(33)29-25(31)34)8-12-23(32)28-14-18-7-11-21(27)22(13-18)37-4/h5-7,9-11,13,16,30H,14-15H2,1-4H3,(H,28,32)(H,29,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	141	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemistry and Biotechnology, Center for Organic and Medicinal Chemistry, ZHAW Zurich University of Applied Sciences , Einsiedlerstrasse 31, 8820 Wädenswil, Switzerland. Curated by ChEMBL					Assay Description Inhibition of MMP10 (unknown origin) assessed using (5-FAM/QX) FRET peptide as substrate by fluorescence assay				J Med Chem 60: 9585-9598 (2017) Article DOI: 10.1021/acs.jmedchem.7b01001 BindingDB Entry DOI: 10.7270/Q280551H
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50250174 (CHEMBL4079271) Show SMILES COc1cc(CNC(=O)C#Cc2cn(Cc3ccc(cc3)S(=O)(=O)NC(C)C)c(=O)[nH]c2=O)ccc1F Show InChI InChI=1S/C25H25FN4O6S/c1-16(2)29-37(34,35)20-8-4-17(5-9-20)14-30-15-19(24(32)28-25(30)33)7-11-23(31)27-13-18-6-10-21(26)22(12-18)36-3/h4-6,8-10,12,15-16,29H,13-14H2,1-3H3,(H,27,31)(H,28,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	141	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemistry and Biotechnology, Center for Organic and Medicinal Chemistry, ZHAW Zurich University of Applied Sciences , Einsiedlerstrasse 31, 8820 Wädenswil, Switzerland. Curated by ChEMBL					Assay Description Inhibition of MMP10 (unknown origin) assessed using (5-FAM/QX) FRET peptide as substrate by fluorescence assay				J Med Chem 60: 9585-9598 (2017) Article DOI: 10.1021/acs.jmedchem.7b01001 BindingDB Entry DOI: 10.7270/Q280551H
					More data for this Ligand-Target Pair

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