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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Proteasome subunit alpha type-2 (Saccharomyces cerevisiae s288c (Yeast)) | BDBM154579 ((2S)-2-[(2S)-2-hexanamido-3-methylbutanamido]-N,N-...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet  | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of California at San Diego; University of Campinas | Assay Description One nanomolar of proteasome was incubated with different inhibitor concentrations in Tris 25 mM pH 7.5; SDS 0.03%; EDTA 0.5 mM for 15 min at 37 °C in... | Chem Biol 21: 782-91 (2014) Article DOI: 10.1016/j.chembiol.2014.04.010 BindingDB Entry DOI: 10.7270/Q2QR4VVS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Proteasome subunit alpha type-2 (Saccharomyces cerevisiae s288c (Yeast)) | BDBM154578 (Carmaphycin A (1)) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of California at San Diego; University of Campinas | Assay Description One nanomolar of proteasome was incubated with different inhibitor concentrations in Tris 25 mM pH 7.5; SDS 0.03%; EDTA 0.5 mM for 15 min at 37 °C in... | Chem Biol 21: 782-91 (2014) Article DOI: 10.1016/j.chembiol.2014.04.010 BindingDB Entry DOI: 10.7270/Q2QR4VVS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Proteasome subunit alpha type-2 (Saccharomyces cerevisiae s288c (Yeast)) | BDBM154578 (Carmaphycin A (1)) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 46.2 | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of California at San Diego; University of Campinas | Assay Description One nanomolar of proteasome was incubated with different inhibitor concentrations in Tris 25 mM pH 7.5; SDS 0.03%; EDTA 0.5 mM for 15 min at 37 °C in... | Chem Biol 21: 782-91 (2014) Article DOI: 10.1016/j.chembiol.2014.04.010 BindingDB Entry DOI: 10.7270/Q2QR4VVS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Proteasome subunit alpha type-2 (Saccharomyces cerevisiae s288c (Yeast)) | BDBM154579 ((2S)-2-[(2S)-2-hexanamido-3-methylbutanamido]-N,N-...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 112 | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of California at San Diego; University of Campinas | Assay Description One nanomolar of proteasome was incubated with different inhibitor concentrations in Tris 25 mM pH 7.5; SDS 0.03%; EDTA 0.5 mM for 15 min at 37 °C in... | Chem Biol 21: 782-91 (2014) Article DOI: 10.1016/j.chembiol.2014.04.010 BindingDB Entry DOI: 10.7270/Q2QR4VVS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Proteasome subunit alpha type-2 (Saccharomyces cerevisiae s288c (Yeast)) | BDBM154579 ((2S)-2-[(2S)-2-hexanamido-3-methylbutanamido]-N,N-...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 165 | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of California at San Diego; University of Campinas | Assay Description One nanomolar of proteasome was incubated with different inhibitor concentrations in Tris 25 mM pH 7.5; SDS 0.03%; EDTA 0.5 mM for 15 min at 37 °C in... | Chem Biol 21: 782-91 (2014) Article DOI: 10.1016/j.chembiol.2014.04.010 BindingDB Entry DOI: 10.7270/Q2QR4VVS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Proteasome subunit alpha type-2 (Saccharomyces cerevisiae s288c (Yeast)) | BDBM154579 ((2S)-2-[(2S)-2-hexanamido-3-methylbutanamido]-N,N-...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of California at San Diego; University of Campinas | Assay Description One nanomolar of proteasome was incubated with different inhibitor concentrations in Tris 25 mM pH 7.5; SDS 0.03%; EDTA 0.5 mM for 15 min at 37 °C in... | Chem Biol 21: 782-91 (2014) Article DOI: 10.1016/j.chembiol.2014.04.010 BindingDB Entry DOI: 10.7270/Q2QR4VVS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
