Compile Data Set for Download or QSAR

Found 361 hits of ic50 data for polymerid = 7499   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microtubule-associated protein tau (Homo sapiens (Human))	CHEMBL5278104 Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50020865 (CHEMBL3286988) Show SMILES COc1cc(\C=c2/sc3nc(cn3c2=O)-c2cccc(Cl)c2)cc(OC)c1O Show InChI InChI=1S/C20H15ClN2O4S/c1-26-15-6-11(7-16(27-2)18(15)24)8-17-19(25)23-10-14(22-20(23)28-17)12-4-3-5-13(21)9-12/h3-10,24H,1-2H3/b17-8-	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Temple University School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assay				ACS Med Chem Lett 5: 619-20 (2014) Article DOI: 10.1021/ml500147n BindingDB Entry DOI: 10.7270/Q2ZW1NGS
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50402408 (CHEMBL2203332) Show SMILES CCCC[N+]1=C(\C=C\c2ccc(cc2)N(CC)CC)C(C)(C)c2ccccc12 |c:4| Show InChI InChI=1S/C26H35N2/c1-6-9-20-28-24-13-11-10-12-23(24)26(4,5)25(28)19-16-21-14-17-22(18-15-21)27(7-2)8-3/h10-19H,6-9,20H2,1-5H3/q+1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.41	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Darmstadt Curated by ChEMBL					Assay Description Displacement of thiazine red R from human Tau aggregate expressed in Escherichia coli after 30 mins by fluorimetric analysis				Bioorg Med Chem Lett 22: 7667-71 (2012) Article DOI: 10.1016/j.bmcl.2012.09.109 BindingDB Entry DOI: 10.7270/Q2TQ62PC
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	CHEMBL5291181 Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	CHEMBL5284020 Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50020860 (CHEMBL3286983) Show SMILES COc1cc(\C=c2/sc3nc(cn3c2=O)-c2ccc(Cl)cc2)cc(Cl)c1O Show InChI InChI=1S/C19H12Cl2N2O3S/c1-26-15-7-10(6-13(21)17(15)24)8-16-18(25)23-9-14(22-19(23)27-16)11-2-4-12(20)5-3-11/h2-9,24H,1H3/b16-8-	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Temple University School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assay				ACS Med Chem Lett 5: 619-20 (2014) Article DOI: 10.1021/ml500147n BindingDB Entry DOI: 10.7270/Q2ZW1NGS
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	CHEMBL5290966 Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50020859 (CHEMBL3286982) Show SMILES COc1cc(\C=c2/sc3nc(cn3c2=O)-c2ccc(Cl)cc2)cc(OC)c1O Show InChI InChI=1S/C20H15ClN2O4S/c1-26-15-7-11(8-16(27-2)18(15)24)9-17-19(25)23-10-14(22-20(23)28-17)12-3-5-13(21)6-4-12/h3-10,24H,1-2H3/b17-9-	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Temple University School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assay				ACS Med Chem Lett 5: 619-20 (2014) Article DOI: 10.1021/ml500147n BindingDB Entry DOI: 10.7270/Q2ZW1NGS
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50398204 (CHEMBL2181532) Show SMILES C1CCN(C1)c1ccc(\C=C\c2cc(\C=C\c3ccc(cc3)N3CCCC3)ncn2)cc1 Show InChI InChI=1S/C28H30N4/c1-2-18-31(17-1)27-13-7-23(8-14-27)5-11-25-21-26(30-22-29-25)12-6-24-9-15-28(16-10-24)32-19-3-4-20-32/h5-16,21-22H,1-4,17-20H2/b11-5+,12-6+	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Darmstadt Curated by ChEMBL					Assay Description Displacement of thiazene red from tau aggregate				J Med Chem 55: 9170-80 (2012) Article DOI: 10.1021/jm300653b BindingDB Entry DOI: 10.7270/Q2PC33HQ
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50020861 (CHEMBL3286984) Show SMILES COc1cc(\C=c2/sc3nc(cn3c2=O)-c2ccc(Cl)cc2)cc(Br)c1O Show InChI InChI=1S/C19H12BrClN2O3S/c1-26-15-7-10(6-13(20)17(15)24)8-16-18(25)23-9-14(22-19(23)27-16)11-2-4-12(21)5-3-11/h2-9,24H,1H3/b16-8-	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Temple University School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assay				ACS Med Chem Lett 5: 619-20 (2014) Article DOI: 10.1021/ml500147n BindingDB Entry DOI: 10.7270/Q2ZW1NGS
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50398203 (CHEMBL2181533) Show SMILES CN(C)c1ccc(\C=C\C=C\c2cc(\C=C\C=C\c3ccc(cc3)N(C)C)ncn2)cc1 Show InChI InChI=1S/C28H30N4/c1-31(2)27-17-13-23(14-18-27)9-5-7-11-25-21-26(30-22-29-25)12-8-6-10-24-15-19-28(20-16-24)32(3)4/h5-22H,1-4H3/b9-5+,10-6+,11-7+,12-8+	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Darmstadt Curated by ChEMBL					Assay Description Displacement of thiazene red from tau aggregate				J Med Chem 55: 9170-80 (2012) Article DOI: 10.1021/jm300653b BindingDB Entry DOI: 10.7270/Q2PC33HQ
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	CHEMBL5268011 Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50020867 (CHEMBL3286989) Show SMILES COc1cc(\C=c2/sc3nc(cn3c2=O)-c2cccc(c2)C(F)(F)F)cc(Cl)c1O Show InChI InChI=1S/C20H12ClF3N2O3S/c1-29-15-6-10(5-13(21)17(15)27)7-16-18(28)26-9-14(25-19(26)30-16)11-3-2-4-12(8-11)20(22,23)24/h2-9,27H,1H3/b16-7-	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Temple University School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assay				ACS Med Chem Lett 5: 619-20 (2014) Article DOI: 10.1021/ml500147n BindingDB Entry DOI: 10.7270/Q2ZW1NGS
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50586984 (CHEMBL5084771) Show SMILES Fc1cc(ccn1)-c1ccc2c(c1)[nH]c1ccncc21 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]PI-2620 from Tau in human brain homogenate incubated for 60 mins by radioligand binding assay				Citation and Details Article DOI: 10.1016/j.bmc.2021.116528 BindingDB Entry DOI: 10.7270/Q2PC3698
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50586985 (CHEMBL5082735) Show SMILES Fc1ncccc1-c1ccc2c(c1)[nH]c1ccncc21 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]PI-2620 from Tau in human brain homogenate incubated for 60 mins by radioligand binding assay				Citation and Details Article DOI: 10.1016/j.bmc.2021.116528 BindingDB Entry DOI: 10.7270/Q2PC3698
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50398207 (CHEMBL2181045) Show SMILES CN(C)c1ccc(\C=C\c2cc(\C=C\c3ccc(cc3)N(C)C)ncn2)cc1 Show InChI InChI=1S/C24H26N4/c1-27(2)23-13-7-19(8-14-23)5-11-21-17-22(26-18-25-21)12-6-20-9-15-24(16-10-20)28(3)4/h5-18H,1-4H3/b11-5+,12-6+	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Darmstadt Curated by ChEMBL					Assay Description Displacement of thiazene red from tau aggregate				J Med Chem 55: 9170-80 (2012) Article DOI: 10.1021/jm300653b BindingDB Entry DOI: 10.7270/Q2PC33HQ
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50586972 (CHEMBL5088921) Show SMILES Fc1cc(ccn1)-c1ccc2c(n1)[nH]c1ccncc21 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]PI-2620 from Tau in human brain homogenate incubated for 60 mins by radioligand binding assay				Citation and Details Article DOI: 10.1016/j.bmc.2021.116528 BindingDB Entry DOI: 10.7270/Q2PC3698
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	CHEMBL5282887 Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50020858 (CHEMBL3286981) Show SMILES COc1cc(\C=c2/sc3nc(cn3c2=O)-c2ccncc2)cc(OC)c1O Show InChI InChI=1S/C19H15N3O4S/c1-25-14-7-11(8-15(26-2)17(14)23)9-16-18(24)22-10-13(21-19(22)27-16)12-3-5-20-6-4-12/h3-10,23H,1-2H3/b16-9-	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Temple University School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assay				ACS Med Chem Lett 5: 619-20 (2014) Article DOI: 10.1021/ml500147n BindingDB Entry DOI: 10.7270/Q2ZW1NGS
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50020862 (CHEMBL3286985) Show SMILES COc1cc(\C=c2/sc3nc(cn3c2=O)-c2ccc(Cl)cc2)cc(O)c1O Show InChI InChI=1S/C19H13ClN2O4S/c1-26-15-7-10(6-14(23)17(15)24)8-16-18(25)22-9-13(21-19(22)27-16)11-2-4-12(20)5-3-11/h2-9,23-24H,1H3/b16-8-	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Temple University School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assay				ACS Med Chem Lett 5: 619-20 (2014) Article DOI: 10.1021/ml500147n BindingDB Entry DOI: 10.7270/Q2ZW1NGS
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50402407 (CHEMBL2207756) Show SMILES C[N+]1=C(\C=C\c2ccc(cc2)N2CCCC2)C(C)(C)c2ccccc12 |c:1| Show InChI InChI=1S/C23H27N2/c1-23(2)20-8-4-5-9-21(20)24(3)22(23)15-12-18-10-13-19(14-11-18)25-16-6-7-17-25/h4-5,8-15H,6-7,16-17H2,1-3H3/q+1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Darmstadt Curated by ChEMBL					Assay Description Displacement of thiazine red R from human Tau aggregate expressed in Escherichia coli after 30 mins by fluorimetric analysis				Bioorg Med Chem Lett 22: 7667-71 (2012) Article DOI: 10.1016/j.bmcl.2012.09.109 BindingDB Entry DOI: 10.7270/Q2TQ62PC
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM610469 ((S)—N-(4-(3-Methylmorpholino)pyridin-3-yl)-2-pheny...) Show SMILES C[C@H]1COCCN1c1ccncc1NC(=O)c1ccnn2cc(nc12)-c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2NC659P
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50398209 (CHEMBL2181041) Show SMILES C1CN(CCO1)c1ccc(\C=C\c2cnc(\C=C\c3ccc(cc3)N3CCOCC3)cn2)cc1 Show InChI InChI=1S/C28H30N4O2/c1(23-3-9-27(10-4-23)31-13-17-33-18-14-31)7-25-21-30-26(22-29-25)8-2-24-5-11-28(12-6-24)32-15-19-34-20-16-32/h1-12,21-22H,13-20H2/b7-1+,8-2+	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Darmstadt Curated by ChEMBL					Assay Description Displacement of thiazene red from tau aggregate				J Med Chem 55: 9170-80 (2012) Article DOI: 10.1021/jm300653b BindingDB Entry DOI: 10.7270/Q2PC33HQ
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50020864 (CHEMBL3286987) Show SMILES COc1cc(\C=c2/sc3nc(cn3c2=O)-c2ccncc2C)cc(OC)c1O Show InChI InChI=1S/C20H17N3O4S/c1-11-9-21-5-4-13(11)14-10-23-19(25)17(28-20(23)22-14)8-12-6-15(26-2)18(24)16(7-12)27-3/h4-10,24H,1-3H3/b17-8-	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Temple University School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assay				ACS Med Chem Lett 5: 619-20 (2014) Article DOI: 10.1021/ml500147n BindingDB Entry DOI: 10.7270/Q2ZW1NGS
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	CHEMBL5266553 Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM610463 (BDBM610464 | BDBM610465 | N-(4-(2-Methylmorpholino...) Show SMILES CC1CN(CCO1)c1ccncc1NC(=O)c1ccnn2cc(nc12)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	MCE PC cid PC sid PDB UniChem		n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2NC659P
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM610463 (BDBM610464 | BDBM610465 | N-(4-(2-Methylmorpholino...) Show SMILES CC1CN(CCO1)c1ccncc1NC(=O)c1ccnn2cc(nc12)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	MCE PC cid PC sid PDB UniChem		n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM551405 (N-methyl-5-(9H-pyrrolo[2,3-b: 4,5-c']dipyridin-2- ...) Show SMILES CNC(=O)c1ccc(cn1)-c1ccc2c(n1)[nH]c1ccncc21 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description [3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...				Citation and Details BindingDB Entry DOI: 10.7270/Q29W0JPZ
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM551431 (5-(7-methoxy-9H-pyrrolo[2,3-b: 4,5-c']dipyridin-2-...) Show SMILES CNC(=O)c1ccc(cn1)-c1ccc2c(n1)[nH]c1cc(OC)ncc21 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description [3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...				Citation and Details BindingDB Entry DOI: 10.7270/Q29W0JPZ
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	CHEMBL5282113 Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50398210 (CHEMBL2181039) Show SMILES COc1ccc(\C=C\c2cnc(\C=C\c3ccc(OC)cc3)cn2)cc1 Show InChI InChI=1S/C22H20N2O2/c1-25-21-11-5-17(6-12-21)3-9-19-15-24-20(16-23-19)10-4-18-7-13-22(26-2)14-8-18/h3-16H,1-2H3/b9-3+,10-4+	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Darmstadt Curated by ChEMBL					Assay Description Displacement of thiazene red from tau aggregate				J Med Chem 55: 9170-80 (2012) Article DOI: 10.1021/jm300653b BindingDB Entry DOI: 10.7270/Q2PC33HQ
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50020869 (CHEMBL3286990) Show SMILES COc1cc(\C=c2/sc3nc(cn3c2=O)-c2cccc(OC(F)(F)F)c2)cc(F)c1O Show InChI InChI=1S/C20H12F4N2O4S/c1-29-15-6-10(5-13(21)17(15)27)7-16-18(28)26-9-14(25-19(26)31-16)11-3-2-4-12(8-11)30-20(22,23)24/h2-9,27H,1H3/b16-7-	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Temple University School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assay				ACS Med Chem Lett 5: 619-20 (2014) Article DOI: 10.1021/ml500147n BindingDB Entry DOI: 10.7270/Q2ZW1NGS
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	CHEMBL5274489 Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM551406 (3-fluoro-5-(9H-pyrrolo[2,3-b: 4,5-c']dipyridin-2- ...) Show SMILES Nc1ncc(cc1F)-c1ccc2c(n1)[nH]c1ccncc21 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description [3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...				Citation and Details BindingDB Entry DOI: 10.7270/Q29W0JPZ
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM551404 (2-[2-(morpholin-4-yl)pyrimidin-5-yl]-9H-pyrrolo[2,...) Show SMILES C1CN(CCO1)c1nccc(n1)-c1ccc2c(n1)[nH]c1ccncc21 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description [3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...				Citation and Details BindingDB Entry DOI: 10.7270/Q29W0JPZ
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM551449 (N-methyl-5-(9H-pyrrolo[2,3-b: 5,4-c']dipyridin-2- ...) Show SMILES CNc1ccc(cn1)-c1ccc2c(n1)[nH]c1cnccc21 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description [3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...				Citation and Details BindingDB Entry DOI: 10.7270/Q29W0JPZ
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM551351 (2-(6-methoxypyridin-3-yl)-9H-pyrrolo[2,3-b: 4,5- |...) Show SMILES COc1ccc(cn1)-c1ccc2c(n1)[nH]c1ccncc21 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description [3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...				Citation and Details BindingDB Entry DOI: 10.7270/Q29W0JPZ
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50586975 (CHEMBL5081662) Show SMILES Fc1ncccc1-c1ccc2c(n1)[nH]c1ccncc21 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]PI-2620 from Tau in human brain homogenate incubated for 60 mins by radioligand binding assay				Citation and Details Article DOI: 10.1016/j.bmc.2021.116528 BindingDB Entry DOI: 10.7270/Q2PC3698
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50398205 (CHEMBL2181531) Show SMILES C1CCN(CC1)c1ccc(\C=C\c2cc(\C=C\c3ccc(cc3)N3CCCCC3)ncn2)cc1 Show InChI InChI=1S/C30H34N4/c1-3-19-33(20-4-1)29-15-9-25(10-16-29)7-13-27-23-28(32-24-31-27)14-8-26-11-17-30(18-12-26)34-21-5-2-6-22-34/h7-18,23-24H,1-6,19-22H2/b13-7+,14-8+	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Darmstadt Curated by ChEMBL					Assay Description Displacement of thiazene red from tau aggregate				J Med Chem 55: 9170-80 (2012) Article DOI: 10.1021/jm300653b BindingDB Entry DOI: 10.7270/Q2PC33HQ
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	CHEMBL5281590 Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50586986 (CHEMBL5091624) Show SMILES Fc1cc(ccn1)-c1nc2[nH]c3ccncc3c2s1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]PI-2620 from Tau in human brain homogenate incubated for 60 mins by radioligand binding assay				Citation and Details Article DOI: 10.1016/j.bmc.2021.116528 BindingDB Entry DOI: 10.7270/Q2PC3698
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	CHEMBL5268820 Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM551435 (5-(7-methoxy-9H-pyrrolo[2,3-b: 4,5-c']dipyridin-2-...) Show SMILES COc1cc2[nH]c3nc(ccc3c2cn1)-c1cnc(Cl)nc1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description [3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...				Citation and Details BindingDB Entry DOI: 10.7270/Q29W0JPZ
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM551305 (2-(2-methoxypyridin-4-yl)-9H-pyrrolo[2,3-b: 4,5- |...) Show SMILES COc1cc(ccn1)-c1ccc2c(n1)[nH]c1ccncc21 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description [3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...				Citation and Details BindingDB Entry DOI: 10.7270/Q29W0JPZ
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM551437 (5-[7-(dimethylamino)-9H-pyrrolo[2,3-b: 4,5- | US11...) Show SMILES CNC(=O)c1ccc(cn1)-c1ccc2c(n1)[nH]c1cc(ncc21)N(C)C Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description [3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...				Citation and Details BindingDB Entry DOI: 10.7270/Q29W0JPZ
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM610453 (2-Phenyl-N-(4-(2,2,2-trifluoroethoxy)pyridin-3-yl)...) Show SMILES FC(F)(F)COc1ccncc1NC(=O)c1ccnn2cc(nc12)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2NC659P
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	CHEMBL5288950 Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	CHEMBL5289779 Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM610460 (N-(4-(4-Fluoropiperidin-1-yl)pyridin-3-yl)-2-pheny...) Show SMILES FC1CCN(CC1)c1ccncc1NC(=O)c1ccnn2cc(nc12)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2NC659P
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	CHEMBL5272041 Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair

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