Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50305863 (3-(3-methoxyphenyl)-5-methyl-6-phenylisoxazolo[4,5...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPR | Bioorg Med Chem Lett 20: 726-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.070 BindingDB Entry DOI: 10.7270/Q2F18ZSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50305859 (5-methyl-3,6-diphenylisoxazolo[4,5-c]pyridin-4(5H)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPR | Bioorg Med Chem Lett 20: 726-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.070 BindingDB Entry DOI: 10.7270/Q2F18ZSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50305864 (3-(2-methoxyphenyl)-5-methyl-6-phenylisoxazolo[4,5...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPR | Bioorg Med Chem Lett 20: 726-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.070 BindingDB Entry DOI: 10.7270/Q2F18ZSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50196289 (6-(4-methoxyphenyl)-5-methyl-3-phenylisoxazolo[4,5...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPR | Bioorg Med Chem Lett 20: 726-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.070 BindingDB Entry DOI: 10.7270/Q2F18ZSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50196291 (6-(benzo[d][1,3]dioxol-5-yl)-5-methyl-3-phenylisox...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPR | Bioorg Med Chem Lett 20: 726-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.070 BindingDB Entry DOI: 10.7270/Q2F18ZSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50305877 (6-(4-methoxyphenyl)-5-methyl-3-(pyridin-4-yl)isoxa...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPR | Bioorg Med Chem Lett 20: 726-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.070 BindingDB Entry DOI: 10.7270/Q2F18ZSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50305862 (3-(4-methoxyphenyl)-5-methyl-6-phenylisoxazolo[4,5...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPR | Bioorg Med Chem Lett 20: 726-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.070 BindingDB Entry DOI: 10.7270/Q2F18ZSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50305873 (6-(3-(dimethylamino)phenyl)-5-methyl-3-phenylisoxa...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPR | Bioorg Med Chem Lett 20: 726-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.070 BindingDB Entry DOI: 10.7270/Q2F18ZSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50305868 (5-methyl-3-phenyl-6-p-tolylisoxazolo[4,5-c]pyridin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPR | Bioorg Med Chem Lett 20: 726-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.070 BindingDB Entry DOI: 10.7270/Q2F18ZSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50305869 (6-(4-fluorophenyl)-5-methyl-3-phenylisoxazolo[4,5-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPR | Bioorg Med Chem Lett 20: 726-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.070 BindingDB Entry DOI: 10.7270/Q2F18ZSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50305874 (5-methyl-3-phenyl-6-(3-(trifluoromethyl)phenyl)iso...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPR | Bioorg Med Chem Lett 20: 726-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.070 BindingDB Entry DOI: 10.7270/Q2F18ZSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50305865 (5-methyl-6-phenyl-3-(pyridin-4-yl)isoxazolo[4,5-c]...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 101 | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPR | Bioorg Med Chem Lett 20: 726-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.070 BindingDB Entry DOI: 10.7270/Q2F18ZSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50305870 (6-(4-(dimethylamino)phenyl)-5-methyl-3-phenylisoxa...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPR | Bioorg Med Chem Lett 20: 726-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.070 BindingDB Entry DOI: 10.7270/Q2F18ZSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50305872 (5-methyl-3-phenyl-6-(4-propylphenyl)isoxazolo[4,5-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPR | Bioorg Med Chem Lett 20: 726-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.070 BindingDB Entry DOI: 10.7270/Q2F18ZSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50305875 (6-(3-fluoro-4-methoxyphenyl)-5-methyl-3-phenylisox...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPR | Bioorg Med Chem Lett 20: 726-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.070 BindingDB Entry DOI: 10.7270/Q2F18ZSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50305866 (5-methyl-6-phenyl-3-(pyridin-3-yl)isoxazolo[4,5-c]...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPR | Bioorg Med Chem Lett 20: 726-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.070 BindingDB Entry DOI: 10.7270/Q2F18ZSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50589650 (CHEMBL5202961) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 263 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.bmcl.2022.128923 BindingDB Entry DOI: 10.7270/Q2KD22VT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50589650 (CHEMBL5202961) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 263 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.bmcl.2022.128923 BindingDB Entry DOI: 10.7270/Q2KD22VT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50531687 (CHEMBL4445682) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 347 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University School of Medicine Curated by ChEMBL | Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc... | J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50531687 (CHEMBL4445682) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 347 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.bmcl.2022.128923 BindingDB Entry DOI: 10.7270/Q2KD22VT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50531687 (CHEMBL4445682) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University School of Medicine Curated by ChEMBL | Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc... | J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50553636 (CHEMBL4750685) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu... | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127529 BindingDB Entry DOI: 10.7270/Q28K7DQ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50553631 (CHEMBL4739931) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu... | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127529 BindingDB Entry DOI: 10.7270/Q28K7DQ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50553632 (CHEMBL4745605) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu... | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127529 BindingDB Entry DOI: 10.7270/Q28K7DQ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50523865 (CHEMBL4476495) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.bmcl.2022.128923 BindingDB Entry DOI: 10.7270/Q2KD22VT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50280369 (CHEMBL4169114) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.bmcl.2022.128923 BindingDB Entry DOI: 10.7270/Q2KD22VT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50523865 (CHEMBL4476495) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.bmcl.2022.128923 BindingDB Entry DOI: 10.7270/Q2KD22VT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50553610 (CHEMBL4793197) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu... | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127529 BindingDB Entry DOI: 10.7270/Q28K7DQ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50280369 (CHEMBL4169114) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Curated by ChEMBL | Assay Description In vitro inhibitory activity against angiotensin I converting enzyme of rats. | ACS Med Chem Lett 8: 1326-1330 (2017) Article DOI: 10.1021/acsmedchemlett.7b00429 BindingDB Entry DOI: 10.7270/Q25X2CG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50280369 (CHEMBL4169114) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 513 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Curated by ChEMBL | Assay Description In vitro inhibitory activity against angiotensin I converting enzyme of rats. | ACS Med Chem Lett 8: 1326-1330 (2017) Article DOI: 10.1021/acsmedchemlett.7b00429 BindingDB Entry DOI: 10.7270/Q25X2CG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50553635 (CHEMBL4743016) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu... | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127529 BindingDB Entry DOI: 10.7270/Q28K7DQ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50280369 (CHEMBL4169114) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.bmcl.2022.128923 BindingDB Entry DOI: 10.7270/Q2KD22VT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50523865 (CHEMBL4476495) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Curated by ChEMBL | Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu... | Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50305876 (6-(3-bromo-4-methoxyphenyl)-5-methyl-3-phenylisoxa...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 580 | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPR | Bioorg Med Chem Lett 20: 726-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.070 BindingDB Entry DOI: 10.7270/Q2F18ZSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50553630 (CHEMBL4758459) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu... | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127529 BindingDB Entry DOI: 10.7270/Q28K7DQ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50553603 (CHEMBL1349403) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 647 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu... | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127529 BindingDB Entry DOI: 10.7270/Q28K7DQ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50280374 (CHEMBL4174742) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 650 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Curated by ChEMBL | Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as decrease in glutamate-induced thallium... | ACS Med Chem Lett 8: 1110-1115 (2017) Article DOI: 10.1021/acsmedchemlett.7b00317 BindingDB Entry DOI: 10.7270/Q2B85BN1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50553644 (CHEMBL4785180) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 670 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu... | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127529 BindingDB Entry DOI: 10.7270/Q28K7DQ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50280374 (CHEMBL4174742) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 676 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Curated by ChEMBL | Assay Description In vitro inhibitory activity against angiotensin I converting enzyme of rats. | ACS Med Chem Lett 8: 1326-1330 (2017) Article DOI: 10.1021/acsmedchemlett.7b00429 BindingDB Entry DOI: 10.7270/Q25X2CG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50280374 (CHEMBL4174742) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 676 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Curated by ChEMBL | Assay Description In vitro inhibitory activity against angiotensin I converting enzyme of rats. | ACS Med Chem Lett 8: 1326-1330 (2017) Article DOI: 10.1021/acsmedchemlett.7b00429 BindingDB Entry DOI: 10.7270/Q25X2CG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50280370 (CHEMBL4160395) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 708 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Curated by ChEMBL | Assay Description In vitro inhibitory activity against angiotensin I converting enzyme of rats. | ACS Med Chem Lett 8: 1326-1330 (2017) Article DOI: 10.1021/acsmedchemlett.7b00429 BindingDB Entry DOI: 10.7270/Q25X2CG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50280370 (CHEMBL4160395) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Curated by ChEMBL | Assay Description In vitro inhibitory activity against angiotensin I converting enzyme of rats. | ACS Med Chem Lett 8: 1326-1330 (2017) Article DOI: 10.1021/acsmedchemlett.7b00429 BindingDB Entry DOI: 10.7270/Q25X2CG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50280368 (CHEMBL4176971) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 759 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University School of Medicine Curated by ChEMBL | Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc... | J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50280368 (CHEMBL4176971) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 759 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.bmcl.2022.128923 BindingDB Entry DOI: 10.7270/Q2KD22VT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50280368 (CHEMBL4176971) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 759 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Curated by ChEMBL | Assay Description In vitro inhibitory activity against angiotensin I converting enzyme of rats. | ACS Med Chem Lett 8: 1326-1330 (2017) Article DOI: 10.1021/acsmedchemlett.7b00429 BindingDB Entry DOI: 10.7270/Q25X2CG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50280368 (CHEMBL4176971) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 760 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Curated by ChEMBL | Assay Description In vitro inhibitory activity against angiotensin I converting enzyme of rats. | ACS Med Chem Lett 8: 1326-1330 (2017) Article DOI: 10.1021/acsmedchemlett.7b00429 BindingDB Entry DOI: 10.7270/Q25X2CG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50280368 (CHEMBL4176971) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 760 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University School of Medicine Curated by ChEMBL | Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc... | J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50280373 (CHEMBL4161847) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 776 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Curated by ChEMBL | Assay Description In vitro inhibitory activity against angiotensin I converting enzyme of rats. | ACS Med Chem Lett 8: 1326-1330 (2017) Article DOI: 10.1021/acsmedchemlett.7b00429 BindingDB Entry DOI: 10.7270/Q25X2CG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50280372 (CHEMBL4165849) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 776 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Curated by ChEMBL | Assay Description In vitro inhibitory activity against angiotensin I converting enzyme of rats. | ACS Med Chem Lett 8: 1326-1330 (2017) Article DOI: 10.1021/acsmedchemlett.7b00429 BindingDB Entry DOI: 10.7270/Q25X2CG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50280373 (CHEMBL4161847) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Curated by ChEMBL | Assay Description In vitro inhibitory activity against angiotensin I converting enzyme of rats. | ACS Med Chem Lett 8: 1326-1330 (2017) Article DOI: 10.1021/acsmedchemlett.7b00429 BindingDB Entry DOI: 10.7270/Q25X2CG2 | |||||||||||
More data for this Ligand-Target Pair |
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