Found 52 hits of ic50 data for polymerid = 8402 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50145156
(CHEMBL3764816)Show SMILES Cn1ncnc1[C@H]1[C@@H](Nc2cc(F)cc3c2c1n[nH]c3=O)c1ccc(F)cc1 |r| Show InChI InChI=1S/C19H14F2N6O/c1-27-18(22-8-23-27)15-16(9-2-4-10(20)5-3-9)24-13-7-11(21)6-12-14(13)17(15)25-26-19(12)28/h2-8,15-16,24H,1H3,(H,26,28)/t15-,16-/m0/s1 | PDB
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PubMed
| n/a | n/a | 254 | n/a | n/a | n/a | n/a | n/a | n/a |
Health& Science University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human His6-tagged PARP4 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins foll... |
J Med Chem 60: 1262-1271 (2017)
Article DOI: 10.1021/acs.jmedchem.6b00990
BindingDB Entry DOI: 10.7270/Q28054VV |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50145156
(CHEMBL3764816)Show SMILES Cn1ncnc1[C@H]1[C@@H](Nc2cc(F)cc3c2c1n[nH]c3=O)c1ccc(F)cc1 |r| Show InChI InChI=1S/C19H14F2N6O/c1-27-18(22-8-23-27)15-16(9-2-4-10(20)5-3-9)24-13-7-11(21)6-12-14(13)17(15)25-26-19(12)28/h2-8,15-16,24H,1H3,(H,26,28)/t15-,16-/m0/s1 | PDB
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| n/a | n/a | 257 | n/a | n/a | n/a | n/a | n/a | n/a |
Health& Science University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human His6-tagged PARP4 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins foll... |
J Med Chem 60: 1262-1271 (2017)
Article DOI: 10.1021/acs.jmedchem.6b00990
BindingDB Entry DOI: 10.7270/Q28054VV |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50316226
((S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-car...)Show SMILES NC(=O)c1cccc2cn(nc12)-c1ccc(cc1)[C@@H]1CCCNC1 |r| Show InChI InChI=1S/C19H20N4O/c20-19(24)17-5-1-3-15-12-23(22-18(15)17)16-8-6-13(7-9-16)14-4-2-10-21-11-14/h1,3,5-9,12,14,21H,2,4,10-11H2,(H2,20,24)/t14-/m1/s1 | PDB
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| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM/Merck Research Labs Rome
Curated by ChEMBL
| Assay Description
Inhibition of human v-PARP catalytic domain by trichloroacetic acid precipitation assay |
J Med Chem 52: 7170-85 (2009)
Article DOI: 10.1021/jm901188v
BindingDB Entry DOI: 10.7270/Q2DN457M |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM27566
(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)Show SMILES Fc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1C(=O)N1CCN(CC1)C(=O)C1CC1 Show InChI InChI=1S/C24H23FN4O3/c25-20-8-5-15(14-21-17-3-1-2-4-18(17)22(30)27-26-21)13-19(20)24(32)29-11-9-28(10-12-29)23(31)16-6-7-16/h1-5,8,13,16H,6-7,9-12,14H2,(H,27,30) | PDB
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| n/a | n/a | 407 | n/a | n/a | n/a | n/a | n/a | n/a |
Health& Science University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human His6-tagged PARP4 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins foll... |
J Med Chem 60: 1262-1271 (2017)
Article DOI: 10.1021/acs.jmedchem.6b00990
BindingDB Entry DOI: 10.7270/Q28054VV |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM27566
(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)Show SMILES Fc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1C(=O)N1CCN(CC1)C(=O)C1CC1 Show InChI InChI=1S/C24H23FN4O3/c25-20-8-5-15(14-21-17-3-1-2-4-18(17)22(30)27-26-21)13-19(20)24(32)29-11-9-28(10-12-29)23(31)16-6-7-16/h1-5,8,13,16H,6-7,9-12,14H2,(H,27,30) | PDB
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| n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
Health& Science University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human His6-tagged PARP4 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins foll... |
J Med Chem 60: 1262-1271 (2017)
Article DOI: 10.1021/acs.jmedchem.6b00990
BindingDB Entry DOI: 10.7270/Q28054VV |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50306253
(1-(2-(pyridin-3-yl)acetyl)-2,3,9,9a-tetrahydro-1H-...)Show InChI InChI=1S/C18H17N3O2/c22-16(9-12-3-2-7-19-10-12)21-8-6-13-4-1-5-14-17(13)15(21)11-20-18(14)23/h1-5,7,10,15H,6,8-9,11H2,(H,20,23) | PDB
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| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-Merck Research Laboratories Rome
Curated by ChEMBL
| Assay Description
Inhibition of VPARP |
Bioorg Med Chem Lett 20: 448-52 (2010)
Article DOI: 10.1016/j.bmcl.2009.12.002
BindingDB Entry DOI: 10.7270/Q2GT5N91 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50316226
((S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-car...)Show SMILES NC(=O)c1cccc2cn(nc12)-c1ccc(cc1)[C@@H]1CCCNC1 |r| Show InChI InChI=1S/C19H20N4O/c20-19(24)17-5-1-3-15-12-23(22-18(15)17)16-8-6-13(7-9-16)14-4-2-10-21-11-14/h1,3,5-9,12,14,21H,2,4,10-11H2,(H2,20,24)/t14-/m1/s1 | PDB
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| n/a | n/a | 446 | n/a | n/a | n/a | n/a | n/a | n/a |
Health& Science University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human His6-tagged PARP4 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins foll... |
J Med Chem 60: 1262-1271 (2017)
Article DOI: 10.1021/acs.jmedchem.6b00990
BindingDB Entry DOI: 10.7270/Q28054VV |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50316226
((S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-car...)Show SMILES NC(=O)c1cccc2cn(nc12)-c1ccc(cc1)[C@@H]1CCCNC1 |r| Show InChI InChI=1S/C19H20N4O/c20-19(24)17-5-1-3-15-12-23(22-18(15)17)16-8-6-13(7-9-16)14-4-2-10-21-11-14/h1,3,5-9,12,14,21H,2,4,10-11H2,(H2,20,24)/t14-/m1/s1 | PDB
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| n/a | n/a | 447 | n/a | n/a | n/a | n/a | n/a | n/a |
Health& Science University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human His6-tagged PARP4 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins foll... |
J Med Chem 60: 1262-1271 (2017)
Article DOI: 10.1021/acs.jmedchem.6b00990
BindingDB Entry DOI: 10.7270/Q28054VV |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50590271
(CHEMBL5198711) | PDB
UniProtKB/SwissProt
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| PC cid
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UniChem
| Article
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| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1039/d1md00195g
BindingDB Entry DOI: 10.7270/Q2H70KS1 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50306256
(1-(3-(pyrazin-2-yl)propanoyl)-2,3,9,9a-tetrahydro-...)Show InChI InChI=1S/C18H18N4O2/c23-16(5-4-13-10-19-7-8-20-13)22-9-6-12-2-1-3-14-17(12)15(22)11-21-18(14)24/h1-3,7-8,10,15H,4-6,9,11H2,(H,21,24) | PDB
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| CHEMBL
PC cid
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| Article
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| n/a | n/a | 660 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-Merck Research Laboratories Rome
Curated by ChEMBL
| Assay Description
Inhibition of VPARP |
Bioorg Med Chem Lett 20: 448-52 (2010)
Article DOI: 10.1016/j.bmcl.2009.12.002
BindingDB Entry DOI: 10.7270/Q2GT5N91 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM27497
(2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridi...)Show InChI InChI=1S/C17H17N3O2/c1-20(2)10-16(21)18-11-7-8-15-14(9-11)12-5-3-4-6-13(12)17(22)19-15/h3-9H,10H2,1-2H3,(H,18,21)(H,19,22) | PDB
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| n/a | n/a | 759 | n/a | n/a | n/a | n/a | n/a | n/a |
Health& Science University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human His6-tagged PARP4 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins foll... |
J Med Chem 60: 1262-1271 (2017)
Article DOI: 10.1021/acs.jmedchem.6b00990
BindingDB Entry DOI: 10.7270/Q28054VV |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50590270
(CHEMBL5181770) | PDB
UniProtKB/SwissProt
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| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1039/d1md00195g
BindingDB Entry DOI: 10.7270/Q2H70KS1 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50590274
(CHEMBL5200299)Show SMILES Cc1cc(I)cc2c1nc(CSc1ccc(cc1)C(O)=O)[nH]c2=O | PDB
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| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1039/d1md00195g
BindingDB Entry DOI: 10.7270/Q2H70KS1 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50446130
(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)Show SMILES CNCc1ccc(cc1)-c1[nH]c2cc(F)cc3C(=O)NCCc1c23 Show InChI InChI=1S/C19H18FN3O/c1-21-10-11-2-4-12(5-3-11)18-14-6-7-22-19(24)15-8-13(20)9-16(23-18)17(14)15/h2-5,8-9,21,23H,6-7,10H2,1H3,(H,22,24) | PDB
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| n/a | n/a | 832 | n/a | n/a | n/a | n/a | n/a | n/a |
Health& Science University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human His6-tagged PARP4 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins foll... |
J Med Chem 60: 1262-1271 (2017)
Article DOI: 10.1021/acs.jmedchem.6b00990
BindingDB Entry DOI: 10.7270/Q28054VV |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50446130
(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)Show SMILES CNCc1ccc(cc1)-c1[nH]c2cc(F)cc3C(=O)NCCc1c23 Show InChI InChI=1S/C19H18FN3O/c1-21-10-11-2-4-12(5-3-11)18-14-6-7-22-19(24)15-8-13(20)9-16(23-18)17(14)15/h2-5,8-9,21,23H,6-7,10H2,1H3,(H,22,24) | PDB
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| n/a | n/a | 839 | n/a | n/a | n/a | n/a | n/a | n/a |
Health& Science University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human His6-tagged PARP4 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins foll... |
J Med Chem 60: 1262-1271 (2017)
Article DOI: 10.1021/acs.jmedchem.6b00990
BindingDB Entry DOI: 10.7270/Q28054VV |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50590273
(CHEMBL5176271)Show SMILES Cc1cc(Br)cc2c1nc(CSc1ccc(cc1)C(O)=O)[nH]c2=O | PDB
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| PC cid
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| Article
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| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1039/d1md00195g
BindingDB Entry DOI: 10.7270/Q2H70KS1 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50590272
(CHEMBL5184065) | PDB
UniProtKB/SwissProt
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| PC cid
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| n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1039/d1md00195g
BindingDB Entry DOI: 10.7270/Q2H70KS1 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM27135
(2-[(2R)-2-methylpyrrolidin-2-yl]-1H-1,3-benzodiazo...)Show InChI InChI=1S/C13H16N4O/c1-13(6-3-7-15-13)12-16-9-5-2-4-8(11(14)18)10(9)17-12/h2,4-5,15H,3,6-7H2,1H3,(H2,14,18)(H,16,17)/t13-/m1/s1 | PDB
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| n/a | n/a | 3.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Health& Science University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human His6-tagged PARP4 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins foll... |
J Med Chem 60: 1262-1271 (2017)
Article DOI: 10.1021/acs.jmedchem.6b00990
BindingDB Entry DOI: 10.7270/Q28054VV |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM27135
(2-[(2R)-2-methylpyrrolidin-2-yl]-1H-1,3-benzodiazo...)Show InChI InChI=1S/C13H16N4O/c1-13(6-3-7-15-13)12-16-9-5-2-4-8(11(14)18)10(9)17-12/h2,4-5,15H,3,6-7H2,1H3,(H2,14,18)(H,16,17)/t13-/m1/s1 | PDB
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| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Health& Science University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human His6-tagged PARP4 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins foll... |
J Med Chem 60: 1262-1271 (2017)
Article DOI: 10.1021/acs.jmedchem.6b00990
BindingDB Entry DOI: 10.7270/Q28054VV |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50188594
(CHEBI:62878 | CHEMBL1086580)Show InChI InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20) | PDB
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| n/a | n/a | 4.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Health& Science University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human His6-tagged PARP4 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins foll... |
J Med Chem 60: 1262-1271 (2017)
Article DOI: 10.1021/acs.jmedchem.6b00990
BindingDB Entry DOI: 10.7270/Q28054VV |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50188594
(CHEBI:62878 | CHEMBL1086580)Show InChI InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20) | PDB
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| n/a | n/a | 4.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Health& Science University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human His6-tagged PARP4 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins foll... |
J Med Chem 60: 1262-1271 (2017)
Article DOI: 10.1021/acs.jmedchem.6b00990
BindingDB Entry DOI: 10.7270/Q28054VV |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50238419
(CHEMBL4060134)Show SMILES Cn1cnc(c1)C(=O)N1CCN(CC1)C(=O)c1ccc(Nc2nc3ccccc3n3nnnc23)cc1 Show InChI InChI=1S/C24H22N10O2/c1-31-14-19(25-15-31)24(36)33-12-10-32(11-13-33)23(35)16-6-8-17(9-7-16)26-21-22-28-29-30-34(22)20-5-3-2-4-18(20)27-21/h2-9,14-15H,10-13H2,1H3,(H,26,27) | PDB
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A GlaxoSmithKline Company
Curated by ChEMBL
| Assay Description
Inhibitory activity against human thymidylate synthase with variable concentration of N5, 10-CH2-H4PteGlu and fixed dUMP (100 uM) |
J Med Chem 60: 5455-5471 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00137
BindingDB Entry DOI: 10.7270/Q2X350RS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50188594
(CHEBI:62878 | CHEMBL1086580)Show InChI InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20) | PDB
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A GlaxoSmithKline Company
Curated by ChEMBL
| Assay Description
Binding affinity to PARP4 in human Jurkat cell extract after 45 mins by mass spectrometric analysis |
J Med Chem 60: 5455-5471 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00137
BindingDB Entry DOI: 10.7270/Q2X350RS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50238425
(CHEMBL4064332)Show InChI InChI=1S/C17H16N6/c1-11(2)12-7-9-13(10-8-12)18-16-17-20-21-22-23(17)15-6-4-3-5-14(15)19-16/h3-11H,1-2H3,(H,18,19) | PDB
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A GlaxoSmithKline Company
Curated by ChEMBL
| Assay Description
Binding affinity to PARP4 in human Jurkat cell extract after 45 mins by mass spectrometric analysis |
J Med Chem 60: 5455-5471 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00137
BindingDB Entry DOI: 10.7270/Q2X350RS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50238428
(CHEMBL4087876)Show SMILES O=C(N1CCOCC1)c1ccc(Nc2nc3ccccc3n3nnnc23)cc1 Show InChI InChI=1S/C19H17N7O2/c27-19(25-9-11-28-12-10-25)13-5-7-14(8-6-13)20-17-18-22-23-24-26(18)16-4-2-1-3-15(16)21-17/h1-8H,9-12H2,(H,20,21) | PDB
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A GlaxoSmithKline Company
Curated by ChEMBL
| Assay Description
Binding affinity to PARP4 in human Jurkat cell extract after 45 mins by mass spectrometric analysis |
J Med Chem 60: 5455-5471 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00137
BindingDB Entry DOI: 10.7270/Q2X350RS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50238416
(CHEMBL4087470)Show SMILES O=C(N1CCN(CC1)c1ncccn1)c1ccc(Nc2nc3ccccc3n3nnnc23)cc1 Show InChI InChI=1S/C23H20N10O/c34-22(31-12-14-32(15-13-31)23-24-10-3-11-25-23)16-6-8-17(9-7-16)26-20-21-28-29-30-33(21)19-5-2-1-4-18(19)27-20/h1-11H,12-15H2,(H,26,27) | PDB
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A GlaxoSmithKline Company
Curated by ChEMBL
| Assay Description
Binding affinity to PARP4 in human Jurkat cell extract after 45 mins by mass spectrometric analysis |
J Med Chem 60: 5455-5471 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00137
BindingDB Entry DOI: 10.7270/Q2X350RS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM431646
(5-[[(2S)-1-(3-Oxo-3-[4-[5-(trifluoromethyl)pyrimid...)Show SMILES C[C@@H](COCCC(=O)N1CCN(CC1)c1ncc(cn1)C(F)(F)F)Nc1cn[nH]c(=O)c1C(F)(F)F |r| | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00281
BindingDB Entry DOI: 10.7270/Q26D5Z03 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50541697
(CHEMBL4633637)Show SMILES CCOc1ccc(nc1)-c1nnc([C@H]2C[C@@H](C2)NC(=O)c2ccccn2)n1-c1ccccc1F |r,wU:15.18,wD:13.13,(2.31,-18.95,;3.77,-18.47,;4.92,-19.5,;6.38,-19.02,;7.54,-20.05,;9,-19.57,;9.31,-18.07,;8.17,-17.04,;6.7,-17.51,;10.77,-17.6,;11.25,-16.13,;12.79,-16.13,;13.26,-17.6,;14.73,-18.07,;15.42,-19.45,;16.8,-18.75,;16.1,-17.38,;18.26,-19.23,;19.41,-18.2,;19.09,-16.69,;20.87,-18.67,;22,-17.64,;23.47,-18.11,;23.79,-19.62,;22.65,-20.65,;21.19,-20.18,;12.02,-18.5,;12.02,-20.04,;10.68,-20.81,;10.68,-22.34,;12.02,-23.12,;13.36,-22.34,;13.35,-20.8,;14.68,-20.03,)| Show InChI InChI=1S/C25H23FN6O2/c1-2-34-18-10-11-20(28-15-18)24-31-30-23(32(24)22-9-4-3-7-19(22)26)16-13-17(14-16)29-25(33)21-8-5-6-12-27-21/h3-12,15-17H,2,13-14H2,1H3,(H,29,33)/t16-,17- | PDB
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University of Oslo
Curated by ChEMBL
| Assay Description
Inhibition of N-terminal His-tagged human ARTD4 (250 to 565 residues) expressed in Escherichia coli Rosetta2 (DE3) using TCEP as substrate after 2.5 ... |
J Med Chem 63: 6834-6846 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00208
BindingDB Entry DOI: 10.7270/Q2RR22SX |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50541697
(CHEMBL4633637)Show SMILES CCOc1ccc(nc1)-c1nnc([C@H]2C[C@@H](C2)NC(=O)c2ccccn2)n1-c1ccccc1F |r,wU:15.18,wD:13.13,(2.31,-18.95,;3.77,-18.47,;4.92,-19.5,;6.38,-19.02,;7.54,-20.05,;9,-19.57,;9.31,-18.07,;8.17,-17.04,;6.7,-17.51,;10.77,-17.6,;11.25,-16.13,;12.79,-16.13,;13.26,-17.6,;14.73,-18.07,;15.42,-19.45,;16.8,-18.75,;16.1,-17.38,;18.26,-19.23,;19.41,-18.2,;19.09,-16.69,;20.87,-18.67,;22,-17.64,;23.47,-18.11,;23.79,-19.62,;22.65,-20.65,;21.19,-20.18,;12.02,-18.5,;12.02,-20.04,;10.68,-20.81,;10.68,-22.34,;12.02,-23.12,;13.36,-22.34,;13.35,-20.8,;14.68,-20.03,)| Show InChI InChI=1S/C25H23FN6O2/c1-2-34-18-10-11-20(28-15-18)24-31-30-23(32(24)22-9-4-3-7-19(22)26)16-13-17(14-16)29-25(33)21-8-5-6-12-27-21/h3-12,15-17H,2,13-14H2,1H3,(H,29,33)/t16-,17- | PDB
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| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of PARP4 (unknown origin) |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01264
BindingDB Entry DOI: 10.7270/Q21R6VDH |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50250875
(CHEMBL4095003)Show SMILES Clc1ccccc1-n1c(nnc1-c1ccncn1)[C@H]1C[C@@H](C1)n1c2ccc(cc2[nH]c1=O)C#N |r,wU:20.25,wD:18.20,(25.39,-29.03,;24.05,-29.8,;24.05,-31.34,;22.72,-32.11,;21.39,-31.34,;21.39,-29.8,;22.72,-29.03,;22.72,-27.49,;23.97,-26.59,;23.49,-25.13,;21.95,-25.13,;21.48,-26.59,;20.01,-27.07,;19.69,-28.57,;18.22,-29.05,;17.08,-28.02,;17.4,-26.52,;18.87,-26.04,;25.43,-27.07,;26.13,-28.44,;27.5,-27.74,;26.8,-26.37,;28.97,-28.22,;29.44,-29.68,;28.67,-31.01,;29.44,-32.35,;30.98,-32.35,;31.75,-31.01,;30.98,-29.68,;31.46,-28.22,;30.21,-27.31,;30.21,-25.77,;31.75,-33.68,;32.52,-35.01,)| Show InChI InChI=1S/C24H17ClN8O/c25-17-3-1-2-4-20(17)33-22(30-31-23(33)18-7-8-27-13-28-18)15-10-16(11-15)32-21-6-5-14(12-26)9-19(21)29-24(32)34/h1-9,13,15-16H,10-11H2,(H,29,34)/t15-,16- | PDB
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University of Oslo
Curated by ChEMBL
| Assay Description
Inhibition of N-terminal His-tagged human ARTD4 (250 to 565 residues) expressed in Escherichia coli Rosetta2 (DE3) using TCEP as substrate after 2.5 ... |
J Med Chem 63: 6834-6846 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00208
BindingDB Entry DOI: 10.7270/Q2RR22SX |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50579974
(CHEMBL5090849 | US20230322721, Example 154 of WO 2...)Show SMILES CCOc1ccc(nc1)-c1nnc([C@H]2C[C@@H](C2)NC(=O)c2cccc3nccnc23)n1-c1ccccc1F |r,wU:15.18,wD:13.13,(1.18,-57.78,;2.08,-56.54,;3.59,-56.7,;4.49,-55.47,;6.01,-55.63,;6.9,-54.39,;6.29,-53.01,;4.77,-52.84,;3.87,-54.07,;7.18,-51.78,;6.71,-50.31,;7.95,-49.39,;9.21,-50.31,;10.68,-49.82,;12.05,-50.53,;12.76,-49.16,;11.38,-48.45,;14.23,-48.68,;14.56,-47.17,;13.41,-46.13,;16.03,-46.68,;16.34,-45.17,;17.81,-44.69,;18.97,-45.72,;18.65,-47.24,;19.79,-48.27,;19.48,-49.77,;18,-50.26,;16.86,-49.22,;17.18,-47.72,;8.73,-51.78,;9.63,-53.02,;9,-54.41,;9.9,-55.64,;11.41,-55.48,;12.03,-54.08,;11.13,-52.85,;11.75,-51.45,)| | PDB
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| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of PARP4 (unknown origin) |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01264
BindingDB Entry DOI: 10.7270/Q21R6VDH |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50104285
(CHEMBL3593716)Show InChI InChI=1S/C13H20N4O/c1-16-6-8-17(9-7-16)13-14-11-5-3-2-4-10(11)12(18)15-13/h2-9H2,1H3,(H,14,15,18) | PDB
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| n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oulu
Curated by ChEMBL
| Assay Description
Inhibition of human ARTD4 (250 to 565) using 500 nM NAD substrate after 2.5 hrs incubation |
Bioorg Med Chem 23: 4139-49 (2015)
Article DOI: 10.1016/j.bmc.2015.06.063
BindingDB Entry DOI: 10.7270/Q2W66NJ2 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM199181
(4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...)Show InChI InChI=1S/C14H12N2O3/c15-13(17)9-1-5-11(6-2-9)19-12-7-3-10(4-8-12)14(16)18/h1-8H,(H2,15,17)(H2,16,18) | PDB
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| n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oulu
Curated by ChEMBL
| Assay Description
Inhibition of N-terminal His-tagged human ARTD4 (250 to 565 residues) expressed in Escherichia coli Rosetta2 (DE3) using TCEP as substrate after 2.5 ... |
Eur J Med Chem 156: 93-102 (2018)
Article DOI: 10.1016/j.ejmech.2018.06.047
BindingDB Entry DOI: 10.7270/Q2P271SW |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50104286
(CHEMBL3593715)Show InChI InChI=1S/C18H23N5O/c24-17-15-3-1-2-4-16(15)20-18(21-17)23-11-9-22(10-12-23)13-14-5-7-19-8-6-14/h5-8H,1-4,9-13H2,(H,20,21,24) | PDB
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| n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oulu
Curated by ChEMBL
| Assay Description
Inhibition of human ARTD4 (250 to 565) using 500 nM NAD substrate after 2.5 hrs incubation |
Bioorg Med Chem 23: 4139-49 (2015)
Article DOI: 10.1016/j.bmc.2015.06.063
BindingDB Entry DOI: 10.7270/Q2W66NJ2 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50234915
(CHEMBL4069447)Show SMILES Cc1cccc2c1nc(CCC(=O)Nc1ccc(cc1)C(=O)Nc1cccc3cccnc13)[nH]c2=O Show InChI InChI=1S/C28H23N5O3/c1-17-5-2-8-21-25(17)32-23(33-28(21)36)14-15-24(34)30-20-12-10-19(11-13-20)27(35)31-22-9-3-6-18-7-4-16-29-26(18)22/h2-13,16H,14-15H2,1H3,(H,30,34)(H,31,35)(H,32,33,36) | PDB
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| n/a | n/a | 6.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description
Inhibition of PARP4 (unknown origin) |
J Med Chem 60: 814-820 (2017)
Article DOI: 10.1021/acs.jmedchem.6b01574
BindingDB Entry DOI: 10.7270/Q20R9RPP |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50340090
(4-methoxybenzamide | CHEMBL449635)Show InChI InChI=1S/C8H9NO2/c1-11-7-4-2-6(3-5-7)8(9)10/h2-5H,1H3,(H2,9,10) | PDB
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| n/a | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oulu
Curated by ChEMBL
| Assay Description
Inhibition of N-terminal His-tagged human ARTD4 (250 to 565 residues) expressed in Escherichia coli Rosetta2 (DE3) using TCEP as substrate after 2.5 ... |
Eur J Med Chem 156: 93-102 (2018)
Article DOI: 10.1016/j.ejmech.2018.06.047
BindingDB Entry DOI: 10.7270/Q2P271SW |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50234915
(CHEMBL4069447)Show SMILES Cc1cccc2c1nc(CCC(=O)Nc1ccc(cc1)C(=O)Nc1cccc3cccnc13)[nH]c2=O Show InChI InChI=1S/C28H23N5O3/c1-17-5-2-8-21-25(17)32-23(33-28(21)36)14-15-24(34)30-20-12-10-19(11-13-20)27(35)31-22-9-3-6-18-7-4-16-29-26(18)22/h2-13,16H,14-15H2,1H3,(H,30,34)(H,31,35)(H,32,33,36) | PDB
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| n/a | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description
Inhibition of PARP4 (unknown origin) |
J Med Chem 60: 814-820 (2017)
Article DOI: 10.1021/acs.jmedchem.6b01574
BindingDB Entry DOI: 10.7270/Q20R9RPP |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50234916
(CHEMBL4098188)Show SMILES O=C(CCc1nc2ccccc2c(=O)[nH]1)Nc1ccc(cc1)C(=O)Nc1cccc2cccnc12 Show InChI InChI=1S/C27H21N5O3/c33-24(15-14-23-30-21-8-2-1-7-20(21)27(35)32-23)29-19-12-10-18(11-13-19)26(34)31-22-9-3-5-17-6-4-16-28-25(17)22/h1-13,16H,14-15H2,(H,29,33)(H,31,34)(H,30,32,35) | PDB
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| n/a | n/a | 6.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description
Inhibition of PARP4 (unknown origin) |
J Med Chem 60: 814-820 (2017)
Article DOI: 10.1021/acs.jmedchem.6b01574
BindingDB Entry DOI: 10.7270/Q20R9RPP |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50234916
(CHEMBL4098188)Show SMILES O=C(CCc1nc2ccccc2c(=O)[nH]1)Nc1ccc(cc1)C(=O)Nc1cccc2cccnc12 Show InChI InChI=1S/C27H21N5O3/c33-24(15-14-23-30-21-8-2-1-7-20(21)27(35)32-23)29-19-12-10-18(11-13-19)26(34)31-22-9-3-5-17-6-4-16-28-25(17)22/h1-13,16H,14-15H2,(H,29,33)(H,31,34)(H,30,32,35) | PDB
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| n/a | n/a | 6.92E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description
Inhibition of PARP4 (unknown origin) |
J Med Chem 60: 814-820 (2017)
Article DOI: 10.1021/acs.jmedchem.6b01574
BindingDB Entry DOI: 10.7270/Q20R9RPP |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50468579
(CHEMBL4287262)Show InChI InChI=1S/C14H11NO4/c15-13(16)9-1-5-11(6-2-9)19-12-7-3-10(4-8-12)14(17)18/h1-8H,(H2,15,16)(H,17,18) | PDB
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| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oulu
Curated by ChEMBL
| Assay Description
Inhibition of N-terminal His-tagged human ARTD4 (250 to 565 residues) expressed in Escherichia coli Rosetta2 (DE3) using TCEP as substrate after 2.5 ... |
Eur J Med Chem 156: 93-102 (2018)
Article DOI: 10.1016/j.ejmech.2018.06.047
BindingDB Entry DOI: 10.7270/Q2P271SW |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50250875
(CHEMBL4095003)Show SMILES Clc1ccccc1-n1c(nnc1-c1ccncn1)[C@H]1C[C@@H](C1)n1c2ccc(cc2[nH]c1=O)C#N |r,wU:20.25,wD:18.20,(25.39,-29.03,;24.05,-29.8,;24.05,-31.34,;22.72,-32.11,;21.39,-31.34,;21.39,-29.8,;22.72,-29.03,;22.72,-27.49,;23.97,-26.59,;23.49,-25.13,;21.95,-25.13,;21.48,-26.59,;20.01,-27.07,;19.69,-28.57,;18.22,-29.05,;17.08,-28.02,;17.4,-26.52,;18.87,-26.04,;25.43,-27.07,;26.13,-28.44,;27.5,-27.74,;26.8,-26.37,;28.97,-28.22,;29.44,-29.68,;28.67,-31.01,;29.44,-32.35,;30.98,-32.35,;31.75,-31.01,;30.98,-29.68,;31.46,-28.22,;30.21,-27.31,;30.21,-25.77,;31.75,-33.68,;32.52,-35.01,)| Show InChI InChI=1S/C24H17ClN8O/c25-17-3-1-2-4-20(17)33-22(30-31-23(33)18-7-8-27-13-28-18)15-10-16(11-15)32-21-6-5-14(12-26)9-19(21)29-24(32)34/h1-9,13,15-16H,10-11H2,(H,29,34)/t15-,16- | PDB
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Leibniz-Forschungsinstitut f�r Molekulare Pharmakologie (FMP)
Curated by ChEMBL
| Assay Description
Inhibition of human PARP4 using NAD+ as substrate by fluorescence assay |
J Med Chem 60: 10013-10025 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00883
BindingDB Entry DOI: 10.7270/Q2CJ8GXG |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50136772
(CHEMBL3752492)Show SMILES COc1ccc(cc1)C(=O)Nc1ccc(cc1)C(=O)N(c1ccncn1)c1ccccc1Cl Show InChI InChI=1S/C25H19ClN4O3/c1-33-20-12-8-17(9-13-20)24(31)29-19-10-6-18(7-11-19)25(32)30(23-14-15-27-16-28-23)22-5-3-2-4-21(22)26/h2-16H,1H3,(H,29,31) | PDB
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University of Oulu
Curated by ChEMBL
| Assay Description
Inhibition of human ARTD4 by fluorescence analysis |
Bioorg Med Chem Lett 26: 328-33 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.018
BindingDB Entry DOI: 10.7270/Q20003ZD |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50136755
(CHEMBL3752386)Show SMILES COc1ccc(cc1)C1(CNC(=O)c2ccc(NC(=O)c3ccco3)cc2Cl)CCOCC1 Show InChI InChI=1S/C25H25ClN2O5/c1-31-19-7-4-17(5-8-19)25(10-13-32-14-11-25)16-27-23(29)20-9-6-18(15-21(20)26)28-24(30)22-3-2-12-33-22/h2-9,12,15H,10-11,13-14,16H2,1H3,(H,27,29)(H,28,30) | PDB
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University of Oulu
Curated by ChEMBL
| Assay Description
Inhibition of human ARTD4 by fluorescence analysis |
Bioorg Med Chem Lett 26: 328-33 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.018
BindingDB Entry DOI: 10.7270/Q20003ZD |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50104288
(CHEMBL3594137)Show InChI InChI=1S/C18H20N2O/c1-18(2,3)13-10-8-12(9-11-13)16-19-15-7-5-4-6-14(15)17(21)20-16/h4-11,16,19H,1-3H3,(H,20,21) | PDB
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University of Oulu
Curated by ChEMBL
| Assay Description
Inhibition of human ARTD4 (250 to 565) using 500 nM NAD substrate after 2.5 hrs incubation |
Bioorg Med Chem 23: 4139-49 (2015)
Article DOI: 10.1016/j.bmc.2015.06.063
BindingDB Entry DOI: 10.7270/Q2W66NJ2 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50104287
(CHEMBL3594136)Show InChI InChI=1S/C17H18N2O/c1-11(2)12-7-9-13(10-8-12)16-18-15-6-4-3-5-14(15)17(20)19-16/h3-11,16,18H,1-2H3,(H,19,20) | PDB
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University of Oulu
Curated by ChEMBL
| Assay Description
Inhibition of human ARTD4 (250 to 565) using 500 nM NAD substrate after 2.5 hrs incubation |
Bioorg Med Chem 23: 4139-49 (2015)
Article DOI: 10.1016/j.bmc.2015.06.063
BindingDB Entry DOI: 10.7270/Q2W66NJ2 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50593992
(CHEMBL5186967) | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50594005
(CHEMBL5181947) | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50594010
(CHEMBL5200358) | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50594011
(CHEMBL5200521) | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human)) | BDBM50468581
(CHEMBL4287655)Show InChI InChI=1S/C14H11NO3/c15-14(17)11-3-7-13(8-4-11)18-12-5-1-10(9-16)2-6-12/h1-9H,(H2,15,17) | PDB
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University of Oulu
Curated by ChEMBL
| Assay Description
Inhibition of N-terminal His-tagged human ARTD4 (250 to 565 residues) expressed in Escherichia coli Rosetta2 (DE3) using TCEP as substrate after 2.5 ... |
Eur J Med Chem 156: 93-102 (2018)
Article DOI: 10.1016/j.ejmech.2018.06.047
BindingDB Entry DOI: 10.7270/Q2P271SW |
More data for this
Ligand-Target Pair | |
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