Compile Data Set for Download or QSAR

Found 118 hits of ic50 data for polymerid = 8405   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50594261 (CHEMBL5190289) Show SMILES Cc1cccc(c1)C(=O)N[C@@H](CNC(=O)c1ccc2c(c1)c(=O)[nH][nH]c2=O)C(N)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00281 BindingDB Entry DOI: 10.7270/Q26D5Z03
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50594013 (CHEMBL5195249) Show SMILES Cc1cccc(c1)C(=O)N[C@H](C(N)=O)C(=O)c1ccc2c(c1)c(=O)[nH][nH]c2=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50446131 (CHEMBL3108871) Show SMILES O=c1[nH]c2sccc2c2ccccc12 Show InChI InChI=1S/C11H7NOS/c13-10-8-4-2-1-3-7(8)9-5-6-14-11(9)12-10/h1-6H,(H,12,13)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TEV cleavage site fused N-terminal 6His-tagged PARP15 (482 to 678 residues) (unknown origin) expressed in Escherichia coli Rosetta2 (DE...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116511 BindingDB Entry DOI: 10.7270/Q24B3566
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50594006 (CHEMBL5192839) Show SMILES O=c1[nH][nH]c(=O)c2cc(OCC3CCCC3)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50594006 (CHEMBL5192839) Show SMILES O=c1[nH][nH]c(=O)c2cc(OCC3CCCC3)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	324	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50594010 (CHEMBL5200358) Show SMILES Fc1ccccc1COc1ccc2c(c1)c(=O)[nH][nH]c2=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	363	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50594007 (CHEMBL5187187) Show SMILES O=c1[nH][nH]c(=O)c2cc(OCC3CCC3)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50594010 (CHEMBL5200358) Show SMILES Fc1ccccc1COc1ccc2c(c1)c(=O)[nH][nH]c2=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50594007 (CHEMBL5187187) Show SMILES O=c1[nH][nH]c(=O)c2cc(OCC3CCC3)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50594005 (CHEMBL5181947) Show SMILES O=c1[nH][nH]c(=O)c2cc(OCC3CCCCC3)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50594011 (CHEMBL5200521) Show SMILES O=c1[nH][nH]c(=O)c2cc(OCc3ccsc3)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50594005 (CHEMBL5181947) Show SMILES O=c1[nH][nH]c(=O)c2cc(OCC3CCCCC3)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50594011 (CHEMBL5200521) Show SMILES O=c1[nH][nH]c(=O)c2cc(OCc3ccsc3)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50594250 (CHEMBL5207717) Show SMILES CC#Cc1ccc2c(nc(CSc3ccc(cc3)C(O)=O)[nH]c2=O)c1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	496	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00281 BindingDB Entry DOI: 10.7270/Q26D5Z03
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50594262 (CHEMBL5187652) Show SMILES CNC(=O)[C@H](CNC(=O)c1ccc2c(c1)c(=O)[nH][nH]c2=O)NC(=O)c1cccc(C)c1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00281 BindingDB Entry DOI: 10.7270/Q26D5Z03
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50242630 (CHEMBL4089522) Show SMILES NC(=O)c1cccc(NC(=O)\C=C/C(=O)N2CCN(CC2)c2ccc(F)cc2)c1 Show InChI InChI=1S/C21H21FN4O3/c22-16-4-6-18(7-5-16)25-10-12-26(13-11-25)20(28)9-8-19(27)24-17-3-1-2-15(14-17)21(23)29/h1-9,14H,10-13H2,(H2,23,29)(H,24,27)/b9-8-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of His6-tagged PARP15 (unknown origin) preincubated for 15 mins followed by biotinylated NAD+ addition by chemiluminescence assay				Bioorg Med Chem Lett 27: 2907-2911 (2017) Article DOI: 10.1016/j.bmcl.2017.04.089 BindingDB Entry DOI: 10.7270/Q24X5B5F
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50587477 (CHEMBL5084343) Show SMILES COc1ccc2c(c1)c1ccsc1[nH]c2=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	525	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP15 (482 to 678 residues) (unknown origin) expressed in Escherichia coli using NAD+ as substrate incubated for 3 hrs by fluorescence...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116511 BindingDB Entry DOI: 10.7270/Q24B3566
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50587477 (CHEMBL5084343) Show SMILES COc1ccc2c(c1)c1ccsc1[nH]c2=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	527	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP15 (482 to 678 residues) (unknown origin) expressed in Escherichia coli using NAD+ as substrate incubated for 3 hrs by fluorescence...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116511 BindingDB Entry DOI: 10.7270/Q24B3566
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50594001 (CHEMBL5186481) Show SMILES NC(=O)c1ccc(OCc2cccc(Br)c2)cc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	589	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50594001 (CHEMBL5186481) Show SMILES NC(=O)c1ccc(OCc2cccc(Br)c2)cc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50594263 (CHEMBL5200663) Show SMILES NC(=O)[C@H](CNC(=O)c1ccc2c(c1)c(=O)[nH][nH]c2=O)NC(=O)COc1ccc2ccc(=O)oc2c1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00281 BindingDB Entry DOI: 10.7270/Q26D5Z03
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50587476 (CHEMBL5083566) Show SMILES CC(C)Oc1ccc2c(c1)c1ccsc1[nH]c2=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP15 (482 to 678 residues) (unknown origin) expressed in Escherichia coli using NAD+ as substrate incubated for 3 hrs by fluorescence...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116511 BindingDB Entry DOI: 10.7270/Q24B3566
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50587476 (CHEMBL5083566) Show SMILES CC(C)Oc1ccc2c(c1)c1ccsc1[nH]c2=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP15 (482 to 678 residues) (unknown origin) expressed in Escherichia coli using NAD+ as substrate incubated for 3 hrs by fluorescence...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116511 BindingDB Entry DOI: 10.7270/Q24B3566
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50468597 (CHEMBL4293771) Show SMILES NC(=O)c1ccc(OCc2cccc(Br)c2)cc1 Show InChI InChI=1S/C14H12BrNO2/c15-12-3-1-2-10(8-12)9-18-13-6-4-11(5-7-13)14(16)17/h1-8H,9H2,(H2,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP15 (482 to 678 residues) (unknown origin) expressed in Escherichia coli using NAD+ as substrate incubated for 3 hrs by fluorescence...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116511 BindingDB Entry DOI: 10.7270/Q24B3566
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50594008 (CHEMBL5181107) Show SMILES O=c1[nH][nH]c(=O)c2cc(OCC3CC3)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50594008 (CHEMBL5181107) Show SMILES O=c1[nH][nH]c(=O)c2cc(OCC3CC3)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50594009 (CHEMBL5171357) Show SMILES Brc1cccc(COc2ccc3c(c2)c(=O)[nH][nH]c3=O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50594009 (CHEMBL5171357) Show SMILES Brc1cccc(COc2ccc3c(c2)c(=O)[nH][nH]c3=O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50587474 (CHEMBL5077731) Show SMILES Oc1ccc2c(c1)c1ccsc1[nH]c2=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP15 (482 to 678 residues) (unknown origin) expressed in Escherichia coli using NAD+ as substrate incubated for 3 hrs by fluorescence...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116511 BindingDB Entry DOI: 10.7270/Q24B3566
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50079627 (CHEMBL3414768) Show SMILES NC(=O)c1cccc(NC(=O)C2=C(CCC2)C(O)=O)c1 |t:11| Show InChI InChI=1S/C14H14N2O4/c15-12(17)8-3-1-4-9(7-8)16-13(18)10-5-2-6-11(10)14(19)20/h1,3-4,7H,2,5-6H2,(H2,15,17)(H,16,18)(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by ChEMBL					Assay Description Inhibition of hexahistidine-tagged human recombinant ARTD7 catalytic domain (459 to 656 amino acids) expressed in Escherichia coli BL21(DE3) assessed...				Eur J Med Chem 95: 546-51 (2015) Article DOI: 10.1016/j.ejmech.2015.03.067 BindingDB Entry DOI: 10.7270/Q23J3FPJ
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50079627 (CHEMBL3414768) Show SMILES NC(=O)c1cccc(NC(=O)C2=C(CCC2)C(O)=O)c1 |t:11| Show InChI InChI=1S/C14H14N2O4/c15-12(17)8-3-1-4-9(7-8)16-13(18)10-5-2-6-11(10)14(19)20/h1,3-4,7H,2,5-6H2,(H2,15,17)(H,16,18)(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by ChEMBL					Assay Description Inhibition of hexahistidine-tagged human recombinant ARTD7 catalytic domain (459 to 656 amino acids) expressed in Escherichia coli BL21(DE3) assessed...				Eur J Med Chem 95: 546-51 (2015) Article DOI: 10.1016/j.ejmech.2015.03.067 BindingDB Entry DOI: 10.7270/Q23J3FPJ
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50272952 (CHEMBL4126054) Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(N)=O)cc1 Show InChI InChI=1S/C14H12N2O3/c15-13(17)9-4-6-11(7-5-9)19-12-3-1-2-10(8-12)14(16)18/h1-8H,(H2,15,17)(H2,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00281 BindingDB Entry DOI: 10.7270/Q26D5Z03
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50079620 (CHEMBL3414775) Show SMILES COC(=O)\C=C/C(=O)Nc1cccc(c1)C(N)=O Show InChI InChI=1S/C12H12N2O4/c1-18-11(16)6-5-10(15)14-9-4-2-3-8(7-9)12(13)17/h2-7H,1H3,(H2,13,17)(H,14,15)/b6-5-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by ChEMBL					Assay Description Inhibition of hexahistidine-tagged human recombinant ARTD7 catalytic domain (459 to 656 amino acids) expressed in Escherichia coli BL21(DE3) assessed...				Eur J Med Chem 95: 546-51 (2015) Article DOI: 10.1016/j.ejmech.2015.03.067 BindingDB Entry DOI: 10.7270/Q23J3FPJ
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50079620 (CHEMBL3414775) Show SMILES COC(=O)\C=C/C(=O)Nc1cccc(c1)C(N)=O Show InChI InChI=1S/C12H12N2O4/c1-18-11(16)6-5-10(15)14-9-4-2-3-8(7-9)12(13)17/h2-7H,1H3,(H2,13,17)(H,14,15)/b6-5-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by ChEMBL					Assay Description Inhibition of hexahistidine-tagged human recombinant ARTD7 catalytic domain (459 to 656 amino acids) expressed in Escherichia coli BL21(DE3) assessed...				Eur J Med Chem 95: 546-51 (2015) Article DOI: 10.1016/j.ejmech.2015.03.067 BindingDB Entry DOI: 10.7270/Q23J3FPJ
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50587478 (CHEMBL5091585) Show SMILES CCOc1ccc2c(c1)c1ccsc1[nH]c2=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP15 (482 to 678 residues) (unknown origin) expressed in Escherichia coli using NAD+ as substrate incubated for 3 hrs by fluorescence...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116511 BindingDB Entry DOI: 10.7270/Q24B3566
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50593997 (CHEMBL5176918) Show SMILES COc1cc(OCc2cccc3ccccc23)ccc1C(N)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50079614 (CHEMBL3414764) Show SMILES C\C(=C\C(=O)Nc1cccc(c1)C(N)=O)C(O)=O Show InChI InChI=1S/C12H12N2O4/c1-7(12(17)18)5-10(15)14-9-4-2-3-8(6-9)11(13)16/h2-6H,1H3,(H2,13,16)(H,14,15)(H,17,18)/b7-5-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by ChEMBL					Assay Description Inhibition of hexahistidine-tagged human recombinant ARTD7 catalytic domain (459 to 656 amino acids) expressed in Escherichia coli BL21(DE3) assessed...				Eur J Med Chem 95: 546-51 (2015) Article DOI: 10.1016/j.ejmech.2015.03.067 BindingDB Entry DOI: 10.7270/Q23J3FPJ
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50079614 (CHEMBL3414764) Show SMILES C\C(=C\C(=O)Nc1cccc(c1)C(N)=O)C(O)=O Show InChI InChI=1S/C12H12N2O4/c1-7(12(17)18)5-10(15)14-9-4-2-3-8(6-9)11(13)16/h2-6H,1H3,(H2,13,16)(H,14,15)(H,17,18)/b7-5-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by ChEMBL					Assay Description Inhibition of hexahistidine-tagged human recombinant ARTD7 catalytic domain (459 to 656 amino acids) expressed in Escherichia coli BL21(DE3) assessed...				Eur J Med Chem 95: 546-51 (2015) Article DOI: 10.1016/j.ejmech.2015.03.067 BindingDB Entry DOI: 10.7270/Q23J3FPJ
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50593992 (CHEMBL5186967) Show SMILES NC(=O)c1ccc(OCC2CCC2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50593992 (CHEMBL5186967) Show SMILES NC(=O)c1ccc(OCC2CCC2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50593994 (CHEMBL5185078) Show SMILES NC(=O)c1ccc(OCc2cncs2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50593996 (CHEMBL5198615) Show SMILES COc1cc(OCc2cccc(Br)c2)ccc1C(N)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50593996 (CHEMBL5198615) Show SMILES COc1cc(OCc2cccc(Br)c2)ccc1C(N)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50593998 (CHEMBL5194963) Show SMILES COc1cc(OCc2ccccc2F)ccc1C(N)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50468579 (CHEMBL4287262) Show SMILES NC(=O)c1ccc(Oc2ccc(cc2)C(O)=O)cc1 Show InChI InChI=1S/C14H11NO4/c15-13(16)9-1-5-11(6-2-9)19-12-7-3-10(4-8-12)14(17)18/h1-8H,(H2,15,16)(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oulu Curated by ChEMBL					Assay Description Inhibition of N-terminal His-tagged human ARTD7 (482 to 678 residues) expressed in Escherichia coli Rosetta2 (DE3) using SRPK2 as substrate after 3 h...				Eur J Med Chem 156: 93-102 (2018) Article DOI: 10.1016/j.ejmech.2018.06.047 BindingDB Entry DOI: 10.7270/Q2P271SW
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50452662 (CHEMBL4208737) Show SMILES NC(=O)c1ccc(OCc2ccccc2F)cc1 Show InChI InChI=1S/C14H12FNO2/c15-13-4-2-1-3-11(13)9-18-12-7-5-10(6-8-12)14(16)17/h1-8H,9H2,(H2,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oulu Curated by ChEMBL					Assay Description Inhibition of N-terminal His-tagged human ARTD7 (482 to 678 residues) expressed in Escherichia coli Rosetta2 (DE3) using SRPK2 as substrate after 3 h...				Eur J Med Chem 156: 93-102 (2018) Article DOI: 10.1016/j.ejmech.2018.06.047 BindingDB Entry DOI: 10.7270/Q2P271SW
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50590275 (CHEMBL5173275) Show SMILES CC#Cc1cc(C)c2nc(CSc3ncccn3)[nH]c(=O)c2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d1md00195g BindingDB Entry DOI: 10.7270/Q2H70KS1
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50593990 (CHEMBL5178227) Show SMILES NC(=O)c1ccc(OCC2CCCCC2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50593990 (CHEMBL5178227) Show SMILES NC(=O)c1ccc(OCC2CCCCC2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	3.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50593991 (CHEMBL5206305) Show SMILES NC(=O)c1ccc(OCC2CCCC2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114362 BindingDB Entry DOI: 10.7270/Q20V8HSS
					More data for this Ligand-Target Pair				3D Structure (crystal)

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