Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lactoperoxidase (Bos taurus (Bovine)) | BDBM217355 (4-benzyl-2-hydroxybenzenecarbohydroxamic acid (HX2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Otago Christchurch | Assay Description The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ... | J Biol Chem 288: 36636-47 (2013) Article DOI: 10.1074/jbc.M113.507756 BindingDB Entry DOI: 10.7270/Q20K27DH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50015089 (2,N-Dihydroxy-benzamide | CHEMBL309339 | N,2-dihyd...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Otago Christchurch | Assay Description The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ... | J Biol Chem 288: 36636-47 (2013) Article DOI: 10.1074/jbc.M113.507756 BindingDB Entry DOI: 10.7270/Q20K27DH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50238831 (CHEMBL251689) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 mins | J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM81461 (CAS_86-54-4 | Hydralazine | Hydralazine (HZN) | NS...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 mins | J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM217356 (2-(benzylamino)-6-oxo-3H-pyrimidine-5-carbohydroxa...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Otago Christchurch | Assay Description The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ... | J Biol Chem 288: 36636-47 (2013) Article DOI: 10.1074/jbc.M113.507756 BindingDB Entry DOI: 10.7270/Q20K27DH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50238837 (CHEMBL581893 | GNF-Pf-3346) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of cathepsin D. | J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50238832 (CHEMBL4080413) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 mins | J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50238827 (CHEMBL4064328) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 mins | J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50238841 (CHEMBL4098162) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description In vitro antagonist activity against rat prostatic androgen receptor (AR) | J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM48320 (4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 mins | J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50489048 (CHEMBL2299190) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article | n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis | Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50489044 (CHEMBL2299191) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis | Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM7460 (2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 6.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 mins | J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50489043 (CHEMBL2299192) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article | n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis | Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM217354 (2-(3,5-bistrifluoromethylbenzylamino)-6-oxo-1H-pyr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Otago Christchurch | Assay Description The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ... | J Biol Chem 288: 36636-47 (2013) Article DOI: 10.1074/jbc.M113.507756 BindingDB Entry DOI: 10.7270/Q20K27DH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50241361 (CHEMBL1515 | METHIMAZOLE | US9138393, Methimazole ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | PDB Article | n/a | n/a | 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis | Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50489045 (CHEMBL2299193) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article | n/a | n/a | 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis | Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50489042 (CHEMBL2295876) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article | n/a | n/a | 1.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis | Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50489049 (CHEMBL2299195) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article | n/a | n/a | 1.43E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis | Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50489046 (CHEMBL2299198) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article | n/a | n/a | 1.74E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis | Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50489041 (CHEMBL2299196) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article | n/a | n/a | 1.78E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis | Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM7458 (5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.78E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 mins | J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50489039 (CHEMBL2299199) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article | n/a | n/a | 2.19E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis | Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50489047 (CHEMBL2299194) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article | n/a | n/a | 2.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis | Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50489040 (CHEMBL2299197) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article | n/a | n/a | 2.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis | Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50489038 (CHEMBL2299200) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article | n/a | n/a | 3.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis | Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50489050 (CHEMBL2299201) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article | n/a | n/a | 9.38E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis | Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50489036 (CHEMBL2299202) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article | n/a | n/a | 1.05E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis | Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50207306 (CHEMBL2140153) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis | Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM50489037 (CHEMBL2299203) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis | Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactoperoxidase (Bos taurus (Bovine)) | BDBM114830 (3-(4-methoxyphenyl)-1H-isochromen-1-one | 3-(4-met...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis | Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB | |||||||||||
More data for this Ligand-Target Pair |