Compile Data Set for Download or QSAR

Found 312 hits of ic50 data for polymerid = 9153   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396227 (6-[5-Bromo-6-(2-oxa-6-aza-spiro[3.3]hept-6-yl)-pyr...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(n1)N1CC2(COC2)C1 Show InChI InChI=1S/C17H17BrN6O2/c1-9-11(13(19)14-15(20-9)23-26-22-14)4-10-2-3-12(18)16(21-10)24-5-17(6-24)7-25-8-17/h2-3H,4-8,19H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0200	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396236 (6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridi...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(C#N)c(NC2CC2)n1 Show InChI InChI=1S/C16H15N7O/c1-8-12(13(18)14-16(19-8)23-24-22-14)6-11-3-2-9(7-17)15(21-11)20-10-4-5-10/h2-3,10H,4-6,18H2,1H3,(H,20,21)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human GOAT expressed in HEK293 cells harboring -preproghrelin in presence of Octanoate-BSA incubated for 5 hr by ELISA				Citation and Details Article DOI: 10.1039/d0md00210k BindingDB Entry DOI: 10.7270/Q2KS6W53
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396236 (6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridi...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(C#N)c(NC2CC2)n1 Show InChI InChI=1S/C16H15N7O/c1-8-12(13(18)14-16(19-8)23-24-22-14)6-11-3-2-9(7-17)15(21-11)20-10-4-5-10/h2-3,10H,4-6,18H2,1H3,(H,20,21)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0200	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396194 (6-(5-Bromo-6-methoxy-pyridin-2-ylmethyl)-5-methyl-...) Show SMILES COc1nc(Cc2c(C)nc3nonc3c2N)ccc1Br Show InChI InChI=1S/C13H12BrN5O2/c1-6-8(10(15)11-12(16-6)19-21-18-11)5-7-3-4-9(14)13(17-7)20-2/h3-4H,5,15H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0220	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396205 (6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridi...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(C#N)c(OCCCF)n1 Show InChI InChI=1S/C16H15FN6O2/c1-9-12(13(19)14-15(20-9)23-25-22-14)7-11-4-3-10(8-18)16(21-11)24-6-2-5-17/h3-4H,2,5-7,19H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0260	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396220 (6-(5-Bromo-6-morpholin-4-yl-pyridin-2-ylmethyl)-5-...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(n1)N1CCOCC1 Show InChI InChI=1S/C16H17BrN6O2/c1-9-11(13(18)14-15(19-9)22-25-21-14)8-10-2-3-12(17)16(20-10)23-4-6-24-7-5-23/h2-3H,4-8,18H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0260	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396246 (6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridi...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(C#N)c(NCCCF)n1 Show InChI InChI=1S/C16H16FN7O/c1-9-12(13(19)14-16(21-9)24-25-23-14)7-11-4-3-10(8-18)15(22-11)20-6-2-5-17/h3-4H,2,5-7,19H2,1H3,(H,20,22)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0270	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396239 (6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridi...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(C#N)c(n1)N1CC(F)(F)C1 Show InChI InChI=1S/C16H13F2N7O/c1-8-11(12(20)13-14(21-8)24-26-23-13)4-10-3-2-9(5-19)15(22-10)25-6-16(17,18)7-25/h2-3H,4,6-7,20H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0270	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM50548078 (CHEMBL4746798) Show SMILES Cc1nc2nonc2c(N)c1Cn1ccc(n1)-c1cccc(n1)C(F)(F)F Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0280	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human GOAT expressed in HEK293 cells harboring -preproghrelin in presence of Octanoate-BSA incubated for 5 hr by ELISA				Citation and Details Article DOI: 10.1039/d0md00210k BindingDB Entry DOI: 10.7270/Q2KS6W53
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396118 (6-(5,6-Dibromo-pyridin-2-ylmethyl)-5-methyl-[1,2,5...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(Br)n1 Show InChI InChI=1S/C12H9Br2N5O/c1-5-7(4-6-2-3-8(13)11(14)17-6)9(15)10-12(16-5)19-20-18-10/h2-3H,4,15H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396219 (1-[6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyr...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(n1)N1CC(C)(O)C1 Show InChI InChI=1S/C16H17BrN6O2/c1-8-10(12(18)13-14(19-8)22-25-21-13)5-9-3-4-11(17)15(20-9)23-6-16(2,24)7-23/h3-4,24H,5-7,18H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0330	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396233 (6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridi...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(C#N)c(n1)N1CCOCC1 Show InChI InChI=1S/C17H17N7O2/c1-10-13(14(19)15-16(20-10)23-26-22-15)8-12-3-2-11(9-18)17(21-12)24-4-6-25-7-5-24/h2-3H,4-8,19H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0330	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396197 (6-[5-Bromo-6-(2-fluoro-ethoxy)-pyridin-2-ylmethyl]...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(OCCF)n1 Show InChI InChI=1S/C14H13BrFN5O2/c1-7-9(11(17)12-13(18-7)21-23-20-12)6-8-2-3-10(15)14(19-8)22-5-4-16/h2-3H,4-6,17H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0340	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396112 (6-(6-Bromo-5-difluoromethoxy-pyridin-2-ylmethyl)-5...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(OC(F)F)c(Br)n1 Show InChI InChI=1S/C13H10BrF2N5O2/c1-5-7(9(17)10-12(18-5)21-23-20-10)4-6-2-3-8(11(14)19-6)22-13(15)16/h2-3,13H,4,17H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0380	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396222 (6-(5-Bromo-6-cyclopropylamino-pyridin-2-ylmethyl)-...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(NC2CC2)n1 Show InChI InChI=1S/C15H15BrN6O/c1-7-10(12(17)13-15(18-7)22-23-21-13)6-9-4-5-11(16)14(20-9)19-8-2-3-8/h4-5,8H,2-3,6,17H2,1H3,(H,19,20)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0380	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396218 (6-{5-Bromo-6-[(3-methyl-oxetan-3-ylmethyl)-amino]-...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(NCC2(C)COC2)n1 Show InChI InChI=1S/C17H19BrN6O2/c1-9-11(13(19)14-16(21-9)24-26-23-14)5-10-3-4-12(18)15(22-10)20-6-17(2)7-25-8-17/h3-4H,5-8,19H2,1-2H3,(H,20,22)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0450	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396240 (6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridi...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(C#N)c(n1)N1CCC(F)(F)C1 Show InChI InChI=1S/C17H15F2N7O/c1-9-12(13(21)14-15(22-9)25-27-24-14)6-11-3-2-10(7-20)16(23-11)26-5-4-17(18,19)8-26/h2-3H,4-6,8,21H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0460	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396116 (6-(5-Brom32.2-chloro-pyridin-2-ylmethyl)-5-methyl-...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(Cl)n1 Show InChI InChI=1S/C12H9BrClN5O/c1-5-7(4-6-2-3-8(13)11(14)17-6)9(15)10-12(16-5)19-20-18-10/h2-3H,4,15H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0470	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396164 (6-(6-Amino-5-thiazol-5-yl-pyridin-2-ylmethyl)-5-me...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(-c2cncs2)c(N)n1 Show InChI InChI=1S/C15H13N7OS/c1-7-10(12(16)13-15(19-7)22-23-21-13)4-8-2-3-9(14(17)20-8)11-5-18-6-24-11/h2-3,5-6H,4,16H2,1H3,(H2,17,20)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0500	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396226 (6-[5-Bromo-6-(3,3-difluoro-azetidin-1-yl)-pyridin-...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(n1)N1CC(F)(F)C1 Show InChI InChI=1S/C15H13BrF2N6O/c1-7-9(11(19)12-13(20-7)23-25-22-12)4-8-2-3-10(16)14(21-8)24-5-15(17,18)6-24/h2-3H,4-6,19H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0520	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396234 (6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridi...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(C#N)c(n1)N1CC2(COC2)C1 Show InChI InChI=1S/C18H17N7O2/c1-10-13(14(20)15-16(21-10)24-27-23-15)4-12-3-2-11(5-19)17(22-12)25-6-18(7-25)8-26-9-18/h2-3H,4,6-9,20H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0540	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396241 (6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridi...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(C#N)c(NCCC(F)F)n1 Show InChI InChI=1S/C16H15F2N7O/c1-8-11(13(20)14-16(22-8)25-26-24-14)6-10-3-2-9(7-19)15(23-10)21-5-4-12(17)18/h2-3,12H,4-6,20H2,1H3,(H,21,23)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0550	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396221 (3-[6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyr...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(NCC(C)(C)C(N)=O)n1 Show InChI InChI=1S/C17H20BrN7O2/c1-8-10(12(19)13-15(22-8)25-27-24-13)6-9-4-5-11(18)14(23-9)21-7-17(2,3)16(20)26/h4-5H,6-7,19H2,1-3H3,(H2,20,26)(H,21,23)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0560	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396189 (6-[5-Bromo-6-(2,2-difluoro-ethoxy)-pyridin-2-yl me...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(OCC(F)F)n1 Show InChI InChI=1S/C14H12BrF2N5O2/c1-6-8(11(18)12-13(19-6)22-24-21-12)4-7-2-3-9(15)14(20-7)23-5-10(16)17/h2-3,10H,4-5,18H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0580	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396191 (1-[6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyr...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(OCC(C)(C)O)n1 Show InChI InChI=1S/C16H18BrN5O3/c1-8-10(12(18)13-14(19-8)22-25-21-13)6-9-4-5-11(17)15(20-9)24-7-16(2,3)23/h4-5,23H,6-7,18H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0580	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396119 (6-(5-Brom32.2-fluoro-pyridin-2-ylmethyl)-5-methyl-...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(F)n1 Show InChI InChI=1S/C12H9BrFN5O/c1-5-7(4-6-2-3-8(13)11(14)17-6)9(15)10-12(16-5)19-20-18-10/h2-3H,4,15H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0660	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM50548079 (CHEMBL4754865) Show SMILES COc1cc(ccc1Cc1c(C)nc2nonc2c1N)C(F)(F)F Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0660	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human GOAT expressed in HEK293 cells harboring -preproghrelin in presence of Octanoate-BSA incubated for 5 hr by ELISA				Citation and Details Article DOI: 10.1039/d0md00210k BindingDB Entry DOI: 10.7270/Q2KS6W53
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396196 (6-[5-Bromo-6-(2,2-difluoro-propoxy)-pyridin-2-ylme...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(OCC(C)(F)F)n1 Show InChI InChI=1S/C15H14BrF2N5O2/c1-7-9(11(19)12-13(20-7)23-25-22-12)5-8-3-4-10(16)14(21-8)24-6-15(2,17)18/h3-4H,5-6,19H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0720	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396139 (6-(7-amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridi...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(C2CC2)c(n1)C#N Show InChI InChI=1S/C16H14N6O/c1-8-12(14(18)15-16(19-8)22-23-21-15)6-10-4-5-11(9-2-3-9)13(7-17)20-10/h4-5,9H,2-3,6,18H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0730	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396198 (6-[5-Bromo-6-(3-fluoro-propoxy)-pyridin-2-yl methy...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(OCCCF)n1 Show InChI InChI=1S/C15H15BrFN5O2/c1-8-10(12(18)13-14(19-8)22-24-21-13)7-9-3-4-11(16)15(20-9)23-6-2-5-17/h3-4H,2,5-7,18H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0740	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396199 (6-(5-Bromo-6-methylsulfanyl-pyridin-2-ylmethyl)-5-...) Show SMILES CSc1nc(Cc2c(C)nc3nonc3c2N)ccc1Br Show InChI InChI=1S/C13H12BrN5OS/c1-6-8(10(15)11-12(16-6)19-20-18-11)5-7-3-4-9(14)13(17-7)21-2/h3-4H,5,15H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0740	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396235 (6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridi...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(C#N)c(n1)N1CC(C)(O)C1 Show InChI InChI=1S/C17H17N7O2/c1-9-12(13(19)14-15(20-9)23-26-22-14)5-11-4-3-10(6-18)16(21-11)24-7-17(2,25)8-24/h3-4,25H,5,7-8,19H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0750	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396180 (6-[5-bromo-4-(trifluoromethyl)pyrimidin-2-yl]methy...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ncc(Br)c(n1)C(F)(F)F Show InChI InChI=1S/C12H8BrF3N6O/c1-4-5(8(17)9-11(19-4)22-23-21-9)2-7-18-3-6(13)10(20-7)12(14,15)16/h3H,2,17H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0770	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396193 (6-[5-Bromo-6-(2,2,2-trifluoro-ethoxy)-pyridin-2-yl...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(OCC(F)(F)F)n1 Show InChI InChI=1S/C14H11BrF3N5O2/c1-6-8(10(19)11-12(20-6)23-25-22-11)4-7-2-3-9(15)13(21-7)24-5-14(16,17)18/h2-3H,4-5,19H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0790	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396192 (6-[5-Bromo-6-(3-methyl-oxetan-3-ylmethoxy)-pyridin...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(OCC2(C)COC2)n1 Show InChI InChI=1S/C17H18BrN5O3/c1-9-11(13(19)14-15(20-9)23-26-22-14)5-10-3-4-12(18)16(21-10)25-8-17(2)6-24-7-17/h3-4H,5-8,19H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0820	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396120 (6-(5-Brom32.2-difluoromethoxy-pyridin-2-ylmethyl)-...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(OC(F)F)n1 Show InChI InChI=1S/C13H10BrF2N5O2/c1-5-7(9(17)10-11(18-5)21-23-20-10)4-6-2-3-8(14)12(19-6)22-13(15)16/h2-3,13H,4,17H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0820	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396167 (6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridi...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(OC(F)F)c(n1)C#N Show InChI InChI=1S/C14H10F2N6O2/c1-6-8(11(18)12-13(19-6)22-24-21-12)4-7-2-3-10(23-14(15)16)9(5-17)20-7/h2-3,14H,4,18H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0820	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396215 (6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridi...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Oc2ccccc2)c(n1)C#N Show InChI InChI=1S/C19H14N6O2/c1-11-14(17(21)18-19(22-11)25-27-24-18)9-12-7-8-16(15(10-20)23-12)26-13-5-3-2-4-6-13/h2-8H,9,21H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0850	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396200 (6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridi...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(C#N)c(OCC(C)(F)F)n1 Show InChI InChI=1S/C16H14F2N6O2/c1-8-11(12(20)13-14(21-8)24-26-23-13)5-10-4-3-9(6-19)15(22-10)25-7-16(2,17)18/h3-4H,5,7,20H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0860	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396216 (6-(6-Amino-5-difluoromethoxy-pyridin-2-ylmethyl)-5...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(OC(F)F)c(N)n1 Show InChI InChI=1S/C13H12F2N6O2/c1-5-7(9(16)10-12(18-5)21-23-20-10)4-6-2-3-8(11(17)19-6)22-13(14)15/h2-3,13H,4,16H2,1H3,(H2,17,19)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0910	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396206 (6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridi...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(C#N)c(OCC(F)F)n1 Show InChI InChI=1S/C15H12F2N6O2/c1-7-10(12(19)13-14(20-7)23-25-22-13)4-9-3-2-8(5-18)15(21-9)24-6-11(16)17/h2-3,11H,4,6,19H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0930	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396225 (6-[5-Bromo-6-(3,3-difluoro-cyclobutylamino)-pyridi...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(NC2CC(F)(F)C2)n1 Show InChI InChI=1S/C16H15BrF2N6O/c1-7-10(12(20)13-15(21-7)25-26-24-13)4-8-2-3-11(17)14(22-8)23-9-5-16(18,19)6-9/h2-3,9H,4-6,20H2,1H3,(H,22,23)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0960	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396228 (1-[6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyr...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(n1)N1CCNC(=O)CC1 Show InChI InChI=1S/C17H18BrN7O2/c1-9-11(14(19)15-16(21-9)24-27-23-15)8-10-2-3-12(18)17(22-10)25-6-4-13(26)20-5-7-25/h2-3H,4-8,19H2,1H3,(H,20,26)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0970	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396230 (6-[5-Bromo-6-(3,3-difluoro-propylamino)-pyridin-2-...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(NCCC(F)F)n1 Show InChI InChI=1S/C15H15BrF2N6O/c1-7-9(12(19)13-15(21-7)24-25-23-13)6-8-2-3-10(16)14(22-8)20-5-4-11(17)18/h2-3,11H,4-6,19H2,1H3,(H,20,22)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0990	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396208 (6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridi...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(C#N)c(OCC2(C)COC2)n1 Show InChI InChI=1S/C18H18N6O3/c1-10-13(14(20)15-16(21-10)24-27-23-15)5-12-4-3-11(6-19)17(22-12)26-9-18(2)7-25-8-18/h3-4H,5,7-9,20H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396224 (3-[6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyr...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(NCC(C)(C)C#N)n1 Show InChI InChI=1S/C17H18BrN7O/c1-9-11(13(20)14-16(22-9)25-26-24-14)6-10-4-5-12(18)15(23-10)21-8-17(2,3)7-19/h4-5H,6,8,20H2,1-3H3,(H,21,23)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396161 (1-[6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyr...) Show SMILES Cc1nc2nonc2c(N)c1Cc1cccc(n1)C1(CCCC1)C#N Show InChI InChI=1S/C18H18N6O/c1-11-13(15(20)16-17(21-11)24-25-23-16)9-12-5-4-6-14(22-12)18(10-19)7-2-3-8-18/h4-6H,2-3,7-9,20H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396224 (3-[6-(7-Amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyr...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(NCC(C)(C)C#N)n1 Show InChI InChI=1S/C17H18BrN7O/c1-9-11(13(20)14-16(22-9)25-26-24-14)6-10-4-5-12(18)15(23-10)21-8-17(2,3)7-19/h4-5H,6,8,20H2,1-3H3,(H,21,23)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396154 (6-(6-Furan-2-yl-pyridin-2-ylmethyl)-5-methyl-[1,2,...) Show SMILES Cc1nc2nonc2c(N)c1Cc1cccc(n1)-c1ccco1 Show InChI InChI=1S/C16H13N5O2/c1-9-11(14(17)15-16(18-9)21-23-20-15)8-10-4-2-5-12(19-10)13-6-3-7-22-13/h2-7H,8,17H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM396229 (6-[5-Bromo-6-(3,3-difluoro-pyrrolidin-1-yl)-pyridi...) Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(n1)N1CCC(F)(F)C1 Show InChI InChI=1S/C16H15BrF2N6O/c1-8-10(12(20)13-14(21-8)24-26-23-13)6-9-2-3-11(17)15(22-9)25-5-4-16(18,19)7-25/h2-3H,4-7,20H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...				Bioorg Med Chem Lett 17: 4664-9 (2007) BindingDB Entry DOI: 10.7270/Q2VH5R5S
					More data for this Ligand-Target Pair

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