Compile Data Set for Download or QSAR

Found 556 hits of kd data for polymerid = 11077,4916,50006484   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50595843 (CHEMBL5191508) Show SMILES [2H]C([2H])([2H])NC(=O)c1nnc(NC(=O)C2CC2)cc1Nc1cccc(C(=O)Nc2ccc(NC[C@H]3COCCO3)cc2)c1OC |r| Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	<0.0170	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00334 BindingDB Entry DOI: 10.7270/Q25Q5132
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM477067 (US10882859, Example 2(a)) Show SMILES CCc1cc(O)c(F)cc1-c1ccc2c(n[nH]c2c1)-c1nc2CN(CCc2[nH]1)C(=O)N1CCC(CC1)N1CCCCC1 Show InChI InChI=1S/C32H38FN7O2/c1-2-20-17-29(41)25(33)18-24(20)21-6-7-23-27(16-21)36-37-30(23)31-34-26-10-15-40(19-28(26)35-31)32(42)39-13-8-22(9-14-39)38-11-4-3-5-12-38/h6-7,16-18,22,41H,2-5,8-15,19H2,1H3,(H,34,35)(H,36,37)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.0690	n/a	n/a	n/a	n/a	n/a
TOPIVERT PHARMA LIMITED US Patent					Assay Description The biochemical JAK family enzyme binding assays carried out at DiscoveRx.				US Patent US10882859 (2021) BindingDB Entry DOI: 10.7270/Q2NZ8BQR
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM477066 (US10882859, Example 1) Show SMILES CCc1cc(O)c(F)cc1-c1ccc2c(n[nH]c2c1)-c1nc2CN(CCc2[nH]1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H27FN6O3/c1-2-15-12-23(34)19(27)13-18(15)16-3-4-17-21(11-16)30-31-24(17)25-28-20-5-6-33(14-22(20)29-25)26(35)32-7-9-36-10-8-32/h3-4,11-13,34H,2,5-10,14H2,1H3,(H,28,29)(H,30,31)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a
TOPIVERT PHARMA LIMITED US Patent					Assay Description The biochemical JAK family enzyme binding assays carried out at DiscoveRx.				US Patent US10882859 (2021) BindingDB Entry DOI: 10.7270/Q2NZ8BQR
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516350 (US11053241, Compound I-76) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cccc(-c2cn3CCCOc3n2)c1F Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516351 (US11053241, Compound I-77) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1c(F)cc(cc1F)-c1nccn1C Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516352 (US11053241, Compound I-78) Show SMILES CCOc1cc(cc(F)c1-c1cc2c(cnc(NC(=O)C3CC3)c2[nH]1)C(=O)NC)-c1nccn1C Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516353 (US11053241, Compound I-79) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cccc(-c2cn3CCOCc3n2)c1F Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516354 (US11053241, Compound I-80) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1ccn(n1)-c1cnn(C)c1 Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516355 (US11053241, Compound I-81) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cccc(-c2cnc(C)o2)c1F Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516357 (US11053241, Compound I-83) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1c(F)cc(cc1N1CCC(F)(F)C1)-c1nccn1C Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516358 (US11053241, Compound I-84) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cccc(-c2cn3CCOC(C)(C)c3n2)c1F Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516360 (US11053241, Compound I-86) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1c(F)cc(cc1N1CCOCC1)-c1nccn1C Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516361 (US11053241, Compound I-87) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cccc(C2=NC(C)(C)CO2)c1F |t:27| Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516362 (US11053241, Compound I-88) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1ccc(OC[C@@H]2CCCO2)cc1F |r| Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516364 (US11053241, Compound I-90) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1c(F)cc(cc1N1CC[C@H](C1)OC)-c1nccn1C |r| Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516365 (US11053241, Compound I-91) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cccc([C@@H]2C[C@@H](C2)OC)c1F |r,wU:24.26,26.31,(-5.09,-5.64,;-5.09,-4.1,;-3.76,-3.33,;-2.42,-4.1,;-3.76,-1.79,;-5.09,-1.02,;-5.09,.52,;-3.76,1.29,;-3.76,2.83,;-5.09,3.6,;-5.09,5.14,;-6.42,2.83,;-7.96,2.83,;-7.19,1.5,;-2.42,.52,;-.96,1,;-.05,-.25,;-.96,-1.49,;-2.42,-1.02,;1.49,-.25,;2.26,-1.58,;3.8,-1.58,;4.57,-.25,;3.8,1.09,;4.57,2.42,;6.05,2.82,;5.65,4.3,;4.17,3.91,;6.42,5.64,;7.96,5.64,;2.26,1.09,;1.49,2.42,)| Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516366 (US11053241, Compound I-92) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1ccc2nc(C)n(C)c2c1F Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516368 (US11053241, Compound I-94) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cccc([C@H]2C[C@@H](C2)OC)c1F |r,wU:24.26,wD:26.31,(-5.09,-5.64,;-5.09,-4.1,;-3.76,-3.33,;-2.42,-4.1,;-3.76,-1.79,;-5.09,-1.02,;-5.09,.52,;-3.76,1.29,;-3.76,2.83,;-5.09,3.6,;-5.09,5.14,;-6.42,2.83,;-7.96,2.83,;-7.19,1.5,;-2.42,.52,;-.96,1,;-.05,-.25,;-.96,-1.49,;-2.42,-1.02,;1.49,-.25,;2.26,-1.58,;3.8,-1.58,;4.57,-.25,;3.8,1.09,;4.57,2.42,;4.17,3.91,;5.65,4.3,;6.05,2.82,;6.42,5.64,;7.96,5.64,;2.26,1.09,;1.49,2.42,)| Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516369 (US11053241, Compound I-95) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cccc(C2CCCO2)c1F Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516371 (US11053241, Compound I-97) Show SMILES CNC(=O)c1cnc(Nc2ccn(C)n2)c2[nH]c(cc12)-c1cccc(-c2cnn(C)c2)c1F Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516372 (US11053241, Compound I-98) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1ccc(cc1F)C(=O)N1CC(F)(F)C1 Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516373 (US11053241, Compound I-99) Show SMILES CNC(=O)c1cnc(Nc2ccn(C)n2)c2[nH]c(cc12)-c1cccc(-c2cnc(C)o2)c1F Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516374 (US11053241, Compound I-100) Show SMILES CNC(=O)c1cnc(Nc2ccn(C)n2)c2[nH]c(cc12)-c1cccc(-c2cn3CCOCc3n2)c1F Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516024 (US11053241, Compound I-2 | US11053241, Compound I-...) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cccc(c1)-c1ncn(C)n1 Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516278 (US11053241, Compound I-4) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1ccccc1N1CCCS1(=O)=O Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516024 (US11053241, Compound I-2 | US11053241, Compound I-...) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cccc(c1)-c1ncn(C)n1 Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516286 (US11053241, Compound I-12) Show SMILES Cn1cnc(n1)-c1cccc(c1)-c1cc2c(cnc(NC(=O)C3CC3)c2[nH]1)C(N)=O Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516287 (US11053241, Compound I-13 | US11053241, Compound I...) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cc(ccn1)-c1ncn(C)n1 Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516287 (US11053241, Compound I-13 | US11053241, Compound I...) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cc(ccn1)-c1ncn(C)n1 Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516293 (US11053241, Compound I-19) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cccc(-c2cnn(C)c2)c1F Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516295 (US11053241, Compound I-21) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1ccc2ccn(C)c2c1F Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516296 (US11053241, Compound I-22) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cccc(N2CCOCC2)c1F Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516297 (US11053241, Compound I-23) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cccc(-c2ncco2)c1F Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516298 (US11053241, Compound I-24) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1ccc(cc1OC)C(=O)N1CCC1 Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516299 (US11053241, Compound I-25) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1ccc(cc1OC)C(=O)N1CCCC1 Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516300 (US11053241, Compound I-26) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1ccc(cc1OC)N1CCCC1=O Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516301 (US11053241, Compound I-27) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cccc(c1)-c1cnc(C)cn1 Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516304 (US11053241, Compound I-30) Show SMILES CNC(=O)CCCNc1ccc(-c2cc3c(cnc(NC(=O)C4CC4)c3[nH]2)C(=O)NC)c(OC)c1 Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516308 (US11053241, Compound I-34) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cccnc1OC1CC1 Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516310 (US11053241, Compound I-36) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cccc(-c2ncn(C)n2)c1F Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516316 (US11053241, Compound I-42) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1ccc(cc1F)C(=O)N1CCC1 Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516318 (US11053241, Compound I-44) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cnccc1OC1CC1 Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516321 (US11053241, Compound I-47) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cccc(c1F)-n1cnc(C)n1 Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516322 (US11053241, Compound I-48) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cccc(-c2cn(C)cn2)c1F Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516323 (US11053241, Compound I-49) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cccc(n1)-c1nc(C)cn1C Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516326 (US11053241, Compound I-52) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cccc(-c2nnn(C)n2)c1F Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516328 (US11053241, Compound I-54) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1cccn(-c2ncc(C)s2)c1=O Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516332 (US11053241, Compound I-58) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1ccc(cc1F)-c1nccn1C Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516334 (US11053241, Compound I-60) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1ccc(cc1OC)-c1nccs1 Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM516336 (US11053241, Compound I-62) Show SMILES CNC(=O)c1cnc(NC(=O)C2CC2)c2[nH]c(cc12)-c1ccc(cc1F)-c1nncn1C Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q25D8W1J
					More data for this Ligand-Target Pair

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