Compile Data Set for Download or QSAR

Found 12 hits of kd data for polymerid = 1516,50001043,50005684   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen (Homo sapiens (Human))	BDBM50260048 (CHEMBL4084933) Show SMILES [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-]S(=O)(=O)Oc1cc(OCc2ccc(COc3cc(OS([O-])(=O)=O)cc4oc(-c5ccc(OS([O-])(=O)=O)c(OS([O-])(=O)=O)c5)c(OS([O-])(=O)=O)c(=O)c34)cc2)c2c(c1)oc(-c1ccc(OS([O-])(=O)=O)c(OS([O-])(=O)=O)c1)c(OS([O-])(=O)=O)c2=O Show InChI InChI=1S/C38H26O38S8/c39-33-31-27(11-21(69-77(41,42)43)13-29(31)67-35(37(33)75-83(59,60)61)19-5-7-23(71-79(47,48)49)25(9-19)73-81(53,54)55)65-15-17-1-2-18(4-3-17)16-66-28-12-22(70-78(44,45)46)14-30-32(28)34(40)38(76-84(62,63)64)36(68-30)20-6-8-24(72-80(50,51)52)26(10-20)74-82(56,57)58/h1-14H,15-16H2,(H,41,42,43)(H,44,45,46)(H,47,48,49)(H,50,51,52)(H,53,54,55)(H,56,57,58)(H,59,60,61)(H,62,63,64)/p-8	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a
Department of Medicinal Chemistry, and Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University , Richmond, Virginia 23219, United States. Curated by ChEMBL					Assay Description Binding affinity to human plasmin assessed as loss of intrinsic tryptophan fluorescence at 250 uM by spectrofluorometric method				J Med Chem 60: 641-657 (2017) Article DOI: 10.1021/acs.jmedchem.6b01474 BindingDB Entry DOI: 10.7270/Q2CF9SJM
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50260045 (CHEMBL4103815) Show SMILES [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].Cc1cc(COc2cc(OS([O-])(=O)=O)cc3oc(-c4ccc(OS([O-])(=O)=O)c(OS([O-])(=O)=O)c4)c(OS([O-])(=O)=O)c(=O)c23)c(C)cc1COc1cc(OS([O-])(=O)=O)cc2oc(-c3ccc(OS([O-])(=O)=O)c(OS([O-])(=O)=O)c3)c(OS([O-])(=O)=O)c(=O)c12 Show InChI InChI=1S/C40H30O38S8/c1-17-7-22(16-68-30-12-24(72-80(46,47)48)14-32-34(30)36(42)40(78-86(64,65)66)38(70-32)20-4-6-26(74-82(52,53)54)28(10-20)76-84(58,59)60)18(2)8-21(17)15-67-29-11-23(71-79(43,44)45)13-31-33(29)35(41)39(77-85(61,62)63)37(69-31)19-3-5-25(73-81(49,50)51)27(9-19)75-83(55,56)57/h3-14H,15-16H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)(H,55,56,57)(H,58,59,60)(H,61,62,63)(H,64,65,66)/p-8	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a
Department of Medicinal Chemistry, and Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University , Richmond, Virginia 23219, United States. Curated by ChEMBL					Assay Description Binding affinity to human plasmin assessed as loss of intrinsic tryptophan fluorescence at 250 uM by spectrofluorometric method				J Med Chem 60: 641-657 (2017) Article DOI: 10.1021/acs.jmedchem.6b01474 BindingDB Entry DOI: 10.7270/Q2CF9SJM
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50428067 (CL-65336 | Cyklokapron | Lysteda | TRANEXAMIC ACID...) Show SMILES NC[C@H]1CC[C@@H](CC1)C(O)=O |r,wU:5.8,wD:2.1,(1.2,4.21,;-.14,3.44,;-.14,1.9,;-1.47,1.13,;-1.47,-.41,;-.14,-1.18,;1.2,-.41,;1.2,1.13,;-.14,-2.72,;-1.47,-3.49,;1.2,-3.49,)| Show InChI InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem	DrugBank MMDB PDB Article PubMed	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to human plasma full length Glu-plasminogen K1 domain by surface plasmon resonance analysis				ACS Med Chem Lett 5: 538-43 (2014) Article DOI: 10.1021/ml400526d BindingDB Entry DOI: 10.7270/Q2QJ7JV4
					More data for this Ligand-Target Pair				3D Structure (crystal)
Plasminogen (Homo sapiens (Human))	BDBM50428067 (CL-65336 | Cyklokapron | Lysteda | TRANEXAMIC ACID...) Show SMILES NC[C@H]1CC[C@@H](CC1)C(O)=O |r,wU:5.8,wD:2.1,(1.2,4.21,;-.14,3.44,;-.14,1.9,;-1.47,1.13,;-1.47,-.41,;-.14,-1.18,;1.2,-.41,;1.2,1.13,;-.14,-2.72,;-1.47,-3.49,;1.2,-3.49,)| Show InChI InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem	DrugBank MMDB PDB Article PubMed	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a
Philipps University Marburg Curated by ChEMBL					Assay Description Binding affinity to plasminogen K1 domain (unknown origin)				J Med Chem 63: 1445-1472 (2020) Article DOI: 10.1021/acs.jmedchem.9b01060 BindingDB Entry DOI: 10.7270/Q2VQ361P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Plasminogen (Homo sapiens (Human))	BDBM50260047 (CHEMBL4096754) Show SMILES [Na+].[Na+].[Na+].[Na+].Cc1cc(COc2cc(OS([O-])(=O)=O)cc3oc(cc(=O)c23)-c2ccc(OS([O-])(=O)=O)cc2)c(C)cc1COc1cc(OS([O-])(=O)=O)cc2oc(cc(=O)c12)-c1ccc(OS([O-])(=O)=O)cc1 Show InChI InChI=1S/C40H30O22S4/c1-21-11-26(20-56-36-14-30(62-66(52,53)54)16-38-40(36)32(42)18-34(58-38)24-5-9-28(10-6-24)60-64(46,47)48)22(2)12-25(21)19-55-35-13-29(61-65(49,50)51)15-37-39(35)31(41)17-33(57-37)23-3-7-27(8-4-23)59-63(43,44)45/h3-18H,19-20H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)/p-4	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a
Department of Medicinal Chemistry, and Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University , Richmond, Virginia 23219, United States. Curated by ChEMBL					Assay Description Binding affinity to human plasmin assessed as loss of intrinsic tryptophan fluorescence at 250 uM by spectrofluorometric method				J Med Chem 60: 641-657 (2017) Article DOI: 10.1021/acs.jmedchem.6b01474 BindingDB Entry DOI: 10.7270/Q2CF9SJM
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50428067 (CL-65336 | Cyklokapron | Lysteda | TRANEXAMIC ACID...) Show SMILES NC[C@H]1CC[C@@H](CC1)C(O)=O |r,wU:5.8,wD:2.1,(1.2,4.21,;-.14,3.44,;-.14,1.9,;-1.47,1.13,;-1.47,-.41,;-.14,-1.18,;1.2,-.41,;1.2,1.13,;-.14,-2.72,;-1.47,-3.49,;1.2,-3.49,)| Show InChI InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem	DrugBank MMDB PDB Article PubMed	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to human plasma N-terminal truncated Lys-plasminogen K1 domain by surface plasmon resonance analysis				ACS Med Chem Lett 5: 538-43 (2014) Article DOI: 10.1021/ml400526d BindingDB Entry DOI: 10.7270/Q2QJ7JV4
					More data for this Ligand-Target Pair				3D Structure (crystal)
Plasminogen (Homo sapiens (Human))	BDBM50260046 (CHEMBL4060852) Show SMILES [Na+].[Na+].[Na+].[Na+].[O-]S(=O)(=O)Oc1ccc(cc1)-c1cc(=O)c2c(OC\C=C\COc3cc(OS([O-])(=O)=O)cc4oc(cc(=O)c34)-c3ccc(OS([O-])(=O)=O)cc3)cc(OS([O-])(=O)=O)cc2o1 Show InChI InChI=1S/C34H24O22S4/c35-25-17-27(19-3-7-21(8-4-19)53-57(37,38)39)51-31-15-23(55-59(43,44)45)13-29(33(25)31)49-11-1-2-12-50-30-14-24(56-60(46,47)48)16-32-34(30)26(36)18-28(52-32)20-5-9-22(10-6-20)54-58(40,41)42/h1-10,13-18H,11-12H2,(H,37,38,39)(H,40,41,42)(H,43,44,45)(H,46,47,48)/p-4/b2-1+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a
Department of Medicinal Chemistry, and Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University , Richmond, Virginia 23219, United States. Curated by ChEMBL					Assay Description Binding affinity to human plasmin assessed as loss of intrinsic tryptophan fluorescence at 250 uM by spectrofluorometric method				J Med Chem 60: 641-657 (2017) Article DOI: 10.1021/acs.jmedchem.6b01474 BindingDB Entry DOI: 10.7270/Q2CF9SJM
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50260048 (CHEMBL4084933) Show SMILES [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-]S(=O)(=O)Oc1cc(OCc2ccc(COc3cc(OS([O-])(=O)=O)cc4oc(-c5ccc(OS([O-])(=O)=O)c(OS([O-])(=O)=O)c5)c(OS([O-])(=O)=O)c(=O)c34)cc2)c2c(c1)oc(-c1ccc(OS([O-])(=O)=O)c(OS([O-])(=O)=O)c1)c(OS([O-])(=O)=O)c2=O Show InChI InChI=1S/C38H26O38S8/c39-33-31-27(11-21(69-77(41,42)43)13-29(31)67-35(37(33)75-83(59,60)61)19-5-7-23(71-79(47,48)49)25(9-19)73-81(53,54)55)65-15-17-1-2-18(4-3-17)16-66-28-12-22(70-78(44,45)46)14-30-32(28)34(40)38(76-84(62,63)64)36(68-30)20-6-8-24(72-80(50,51)52)26(10-20)74-82(56,57)58/h1-14H,15-16H2,(H,41,42,43)(H,44,45,46)(H,47,48,49)(H,50,51,52)(H,53,54,55)(H,56,57,58)(H,59,60,61)(H,62,63,64)/p-8	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a
Department of Medicinal Chemistry, and Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University , Richmond, Virginia 23219, United States. Curated by ChEMBL					Assay Description Binding affinity to human dansyl-EGR-chloromethylketone-plasmin complex assessed as loss of intrinsic tryptophan fluorescence by spectrofluorometric ...				J Med Chem 60: 641-657 (2017) Article DOI: 10.1021/acs.jmedchem.6b01474 BindingDB Entry DOI: 10.7270/Q2CF9SJM
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50260047 (CHEMBL4096754) Show SMILES [Na+].[Na+].[Na+].[Na+].Cc1cc(COc2cc(OS([O-])(=O)=O)cc3oc(cc(=O)c23)-c2ccc(OS([O-])(=O)=O)cc2)c(C)cc1COc1cc(OS([O-])(=O)=O)cc2oc(cc(=O)c12)-c1ccc(OS([O-])(=O)=O)cc1 Show InChI InChI=1S/C40H30O22S4/c1-21-11-26(20-56-36-14-30(62-66(52,53)54)16-38-40(36)32(42)18-34(58-38)24-5-9-28(10-6-24)60-64(46,47)48)22(2)12-25(21)19-55-35-13-29(61-65(49,50)51)15-37-39(35)31(41)17-33(57-37)23-3-7-27(8-4-23)59-63(43,44)45/h3-18H,19-20H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)/p-4	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a
Department of Medicinal Chemistry, and Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University , Richmond, Virginia 23219, United States. Curated by ChEMBL					Assay Description Binding affinity to human dansyl-EGR-chloromethylketone-plasmin complex assessed as loss of intrinsic tryptophan fluorescence by spectrofluorometric ...				J Med Chem 60: 641-657 (2017) Article DOI: 10.1021/acs.jmedchem.6b01474 BindingDB Entry DOI: 10.7270/Q2CF9SJM
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50357211 (177 J.D. | AMINOCAPROIC ACID | Amicar | Aminocapro...) Show SMILES NCCCCCC(O)=O Show InChI InChI=1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	DrugBank PDB Article PubMed	n/a	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a
Philipps University Marburg Curated by ChEMBL					Assay Description Binding affinity to human plasminogen K1 domain by ultrafiltration technique				J Med Chem 63: 1445-1472 (2020) Article DOI: 10.1021/acs.jmedchem.9b01060 BindingDB Entry DOI: 10.7270/Q2VQ361P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Plasminogen (Homo sapiens (Human))	BDBM50428067 (CL-65336 | Cyklokapron | Lysteda | TRANEXAMIC ACID...) Show SMILES NC[C@H]1CC[C@@H](CC1)C(O)=O |r,wU:5.8,wD:2.1,(1.2,4.21,;-.14,3.44,;-.14,1.9,;-1.47,1.13,;-1.47,-.41,;-.14,-1.18,;1.2,-.41,;1.2,1.13,;-.14,-2.72,;-1.47,-3.49,;1.2,-3.49,)| Show InChI InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem	DrugBank MMDB PDB Article PubMed	n/a	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to human plasma N-terminal truncated Lys-plasminogen by surface plasmon resonance analysis				ACS Med Chem Lett 5: 538-43 (2014) Article DOI: 10.1021/ml400526d BindingDB Entry DOI: 10.7270/Q2QJ7JV4
					More data for this Ligand-Target Pair				3D Structure (crystal)
Plasminogen (Homo sapiens (Human))	BDBM50428067 (CL-65336 | Cyklokapron | Lysteda | TRANEXAMIC ACID...) Show SMILES NC[C@H]1CC[C@@H](CC1)C(O)=O |r,wU:5.8,wD:2.1,(1.2,4.21,;-.14,3.44,;-.14,1.9,;-1.47,1.13,;-1.47,-.41,;-.14,-1.18,;1.2,-.41,;1.2,1.13,;-.14,-2.72,;-1.47,-3.49,;1.2,-3.49,)| Show InChI InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem	DrugBank MMDB PDB Article PubMed	n/a	n/a	n/a	7.50E+5	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to human plasma full length Glu-plasminogen by surface plasmon resonance analysis				ACS Med Chem Lett 5: 538-43 (2014) Article DOI: 10.1021/ml400526d BindingDB Entry DOI: 10.7270/Q2QJ7JV4
					More data for this Ligand-Target Pair				3D Structure (crystal)