Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50095602 (4-[3-(8-Cyclopentyl-2,6-dioxo-1-propyl-1,2,6,7-tet...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.240 | n/a | n/a | n/a | n/a | n/a |
Deakin University Curated by ChEMBL | Assay Description Dissociation constant of [3H]-DPCPX binding to adenosine A1 receptor(AR) at 0.1 nM | J Med Chem 43: 4973-80 (2001) BindingDB Entry DOI: 10.7270/Q2S46R66 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50095602 (4-[3-(8-Cyclopentyl-2,6-dioxo-1-propyl-1,2,6,7-tet...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | n/a |
Deakin University Curated by ChEMBL | Assay Description Dissociation constant of [3H]-DPCPX binding to adenosine A1 receptor(AR) at 0.05 nM | J Med Chem 43: 4973-80 (2001) BindingDB Entry DOI: 10.7270/Q2S46R66 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50095604 (4-[3-(8-Cyclohexyl-2,6-dioxo-1-propyl-1,2,6,7-tetr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | n/a | 0.270 | n/a | n/a | n/a | n/a | n/a |
Deakin University Curated by ChEMBL | Assay Description Dissociation constant of [3H]-DPCPX binding to adenosine A1 receptor (AR) at 0.1 nM | J Med Chem 43: 4973-80 (2001) BindingDB Entry DOI: 10.7270/Q2S46R66 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50095604 (4-[3-(8-Cyclohexyl-2,6-dioxo-1-propyl-1,2,6,7-tetr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | n/a | 0.280 | n/a | n/a | n/a | n/a | n/a |
Deakin University Curated by ChEMBL | Assay Description Dissociation constant of [3H]-DPCPX binding to adenosine A1 receptor (AR) at 0.05 nM | J Med Chem 43: 4973-80 (2001) BindingDB Entry DOI: 10.7270/Q2S46R66 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50095602 (4-[3-(8-Cyclopentyl-2,6-dioxo-1-propyl-1,2,6,7-tet...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.310 | n/a | n/a | n/a | n/a | n/a |
Deakin University Curated by ChEMBL | Assay Description Dissociation constant of [3H]-DPCPX binding to adenosine A1 receptor(AR) at 100 nM | J Med Chem 43: 4973-80 (2001) BindingDB Entry DOI: 10.7270/Q2S46R66 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50095606 (4-(8-Cyclohexyl-2,6-dioxo-1-propyl-1,2,6,7-tetrahy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.320 | n/a | n/a | n/a | n/a | n/a |
Deakin University Curated by ChEMBL | Assay Description Dissociation constant of [3H]-DPCPX binding to adenosine A1 receptor (AR) at 200 nM | J Med Chem 43: 4973-80 (2001) BindingDB Entry DOI: 10.7270/Q2S46R66 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50039676 (4-Fluorosulfonyl-benzoic acid 3-(8-cyclopentyl-2,6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.330 | n/a | n/a | n/a | n/a | n/a |
Deakin University Curated by ChEMBL | Assay Description Dissociation constant of [3H]-DPCPX binding to adenosine A1 receptor (AR) at 5 nM | J Med Chem 43: 4973-80 (2001) BindingDB Entry DOI: 10.7270/Q2S46R66 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50039676 (4-Fluorosulfonyl-benzoic acid 3-(8-cyclopentyl-2,6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.330 | n/a | n/a | n/a | n/a | n/a |
Monash University (Parkville Campus) Curated by ChEMBL | Assay Description Equilibrium dissociation constant for [3H]-DPCPX binding to Adenosine A1 receptor from DDT1 MF2 cell membranes | Bioorg Med Chem Lett 12: 3179-82 (2002) BindingDB Entry DOI: 10.7270/Q24F1Q29 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50039676 (4-Fluorosulfonyl-benzoic acid 3-(8-cyclopentyl-2,6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.330 | n/a | n/a | n/a | n/a | n/a |
Monash University (Parkville Campus) Curated by ChEMBL | Assay Description Equilibrium dissociation constant for [3H]-DPCPX binding to Adenosine A1 receptor from DDT1 MF2 cell membranes | Bioorg Med Chem Lett 12: 3179-82 (2002) BindingDB Entry DOI: 10.7270/Q24F1Q29 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50095604 (4-[3-(8-Cyclohexyl-2,6-dioxo-1-propyl-1,2,6,7-tetr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | n/a | 0.340 | n/a | n/a | n/a | n/a | n/a |
Deakin University Curated by ChEMBL | Assay Description Dissociation constant of [3H]-DPCPX binding to adenosine A1 receptor (AR) at 100 nM | J Med Chem 43: 4973-80 (2001) BindingDB Entry DOI: 10.7270/Q2S46R66 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50095602 (4-[3-(8-Cyclopentyl-2,6-dioxo-1-propyl-1,2,6,7-tet...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.360 | n/a | n/a | n/a | n/a | n/a |
Deakin University Curated by ChEMBL | Assay Description Dissociation constant of [3H]-DPCPX binding to adenosine A1 receptor(AR) at 5 nM | J Med Chem 43: 4973-80 (2001) BindingDB Entry DOI: 10.7270/Q2S46R66 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50095602 (4-[3-(8-Cyclopentyl-2,6-dioxo-1-propyl-1,2,6,7-tet...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.360 | n/a | n/a | n/a | n/a | n/a |
Monash University (Parkville Campus) Curated by ChEMBL | Assay Description Inhibition of NKA-induced airway contraction of isolated hamster trachea (ht) was used as a measure of NK2-receptor antagonist activity. | Bioorg Med Chem Lett 12: 3179-82 (2002) BindingDB Entry DOI: 10.7270/Q24F1Q29 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50095602 (4-[3-(8-Cyclopentyl-2,6-dioxo-1-propyl-1,2,6,7-tet...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.360 | n/a | n/a | n/a | n/a | n/a |
Monash University (Parkville Campus) Curated by ChEMBL | Assay Description Equilibrium dissociation constant for [3H]-DPCPX binding to Adenosine A1 receptor from DDT1 MF2 cell membranes | Bioorg Med Chem Lett 12: 3179-82 (2002) BindingDB Entry DOI: 10.7270/Q24F1Q29 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50095604 (4-[3-(8-Cyclohexyl-2,6-dioxo-1-propyl-1,2,6,7-tetr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | n/a | 0.370 | n/a | n/a | n/a | n/a | n/a |
Deakin University Curated by ChEMBL | Assay Description Dissociation constant of [3H]-DPCPX binding to adenosine A1 receptor (AR) at 5 nM | J Med Chem 43: 4973-80 (2001) BindingDB Entry DOI: 10.7270/Q2S46R66 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50095605 (4-[3-(8-Cyclohexyl-2,6-dioxo-1-propyl-1,2,6,7-tetr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.370 | n/a | n/a | n/a | n/a | n/a |
Deakin University Curated by ChEMBL | Assay Description Dissociation constant of [3H]-DPCPX binding to adenosine A1 receptor (AR) at 200 nM | J Med Chem 43: 4973-80 (2001) BindingDB Entry DOI: 10.7270/Q2S46R66 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50120223 (4-[5-(8-Cyclohexyl-2,6-dioxo-1-propyl-1,2,6,7-tetr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a |
Monash University (Parkville Campus) Curated by ChEMBL | Assay Description Inhibitory concentration against [3H]-DPCPX binding to Adenosine A1 recepto from DDT1 MF2 cells | Bioorg Med Chem Lett 12: 3179-82 (2002) BindingDB Entry DOI: 10.7270/Q24F1Q29 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50120223 (4-[5-(8-Cyclohexyl-2,6-dioxo-1-propyl-1,2,6,7-tetr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a |
Monash University (Parkville Campus) Curated by ChEMBL | Assay Description Equilibrium dissociation constant for [3H]-DPCPX binding to Adenosine A1 receptor from DDT1 MF2 cell membranes | Bioorg Med Chem Lett 12: 3179-82 (2002) BindingDB Entry DOI: 10.7270/Q24F1Q29 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50024563 (CHEMBL3330574) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.460 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Ferrara Curated by ChEMBL | Assay Description Allosteric enhancer activity at human adenosine A1 receptor expressed in CHO cell membranes assessed as [3H]NECA affinity constant at 1 uM (Kd = 0.87... | J Med Chem 57: 7673-86 (2014) Article DOI: 10.1021/jm5008853 BindingDB Entry DOI: 10.7270/Q2SQ91ZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50120222 (4-[5-(8-Cyclopentyl-2,6-dioxo-1-propyl-1,2,6,7-tet...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.530 | n/a | n/a | n/a | n/a | n/a |
Monash University (Parkville Campus) Curated by ChEMBL | Assay Description Equilibrium dissociation constant for [3H]-DPCPX binding to Adenosine A1 receptor from DDT1 MF2 cell membranes | Bioorg Med Chem Lett 12: 3179-82 (2002) BindingDB Entry DOI: 10.7270/Q24F1Q29 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50120221 (4-[5-(8-Bicyclo[2.2.1]hept-2-yl-2,6-dioxo-1-propyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.530 | n/a | n/a | n/a | n/a | n/a |
Monash University (Parkville Campus) Curated by ChEMBL | Assay Description Equilibrium dissociation constant for [3H]-DPCPX binding to Adenosine A1 receptor from DDT1 MF2 cell membranes | Bioorg Med Chem Lett 12: 3179-82 (2002) BindingDB Entry DOI: 10.7270/Q24F1Q29 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50120222 (4-[5-(8-Cyclopentyl-2,6-dioxo-1-propyl-1,2,6,7-tet...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.530 | n/a | n/a | n/a | n/a | n/a |
Monash University (Parkville Campus) Curated by ChEMBL | Assay Description Equilibrium dissociation constant for [3H]-DPCPX binding to Adenosine A1 receptor from DDT1 MF2 cell membranes | Bioorg Med Chem Lett 12: 3179-82 (2002) BindingDB Entry DOI: 10.7270/Q24F1Q29 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50120221 (4-[5-(8-Bicyclo[2.2.1]hept-2-yl-2,6-dioxo-1-propyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.530 | n/a | n/a | n/a | n/a | n/a |
Monash University (Parkville Campus) Curated by ChEMBL | Assay Description Equilibrium dissociation constant for [3H]-DPCPX binding to Adenosine A1 receptor from DDT1 MF2 cell membranes | Bioorg Med Chem Lett 12: 3179-82 (2002) BindingDB Entry DOI: 10.7270/Q24F1Q29 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50039675 (3-[(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.690 | n/a | n/a | n/a | n/a | n/a |
University of South Florida Curated by ChEMBL | Assay Description Specific binding of [3H]-CPX to the A1-adenosine receptor | J Med Chem 37: 2704-12 (1994) BindingDB Entry DOI: 10.7270/Q24748X6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50039675 (3-[(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.690 | n/a | n/a | n/a | n/a | n/a |
University of South Florida Curated by ChEMBL | Assay Description Specific binding of [3H]-CPX to the A1-adenosine receptor | J Med Chem 37: 2704-12 (1994) BindingDB Entry DOI: 10.7270/Q24748X6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50039674 (Bromo-acetic acid 3-(2,6-dioxo-1,3-dipropyl-2,3,6,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.710 | n/a | n/a | n/a | n/a | n/a |
University of South Florida Curated by ChEMBL | Assay Description Specific binding of [3H]-CPX to the A1-adenosine receptor | J Med Chem 37: 2704-12 (1994) BindingDB Entry DOI: 10.7270/Q24748X6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50039676 (4-Fluorosulfonyl-benzoic acid 3-(8-cyclopentyl-2,6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.710 | n/a | n/a | n/a | n/a | n/a |
Deakin University Curated by ChEMBL | Assay Description Dissociation constant of [3H]-DPCPX binding to adenosine A1 receptor (AR) at 100 nM | J Med Chem 43: 4973-80 (2001) BindingDB Entry DOI: 10.7270/Q2S46R66 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50039680 (8-(2,5-Dioxo-2,5-dihydro-pyrrol-1-ylmethyl)-1,3-di...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.730 | n/a | n/a | n/a | n/a | n/a |
University of South Florida Curated by ChEMBL | Assay Description Binding of [3H]-CPX to A1 adenosine receptor of DDT1 MF-2 (DDT) cells | J Med Chem 37: 2704-12 (1994) BindingDB Entry DOI: 10.7270/Q24748X6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50039688 (4-[2-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.740 | n/a | n/a | n/a | n/a | n/a |
University of South Florida Curated by ChEMBL | Assay Description Specific binding of [3H]-CPX to the A1-adenosine receptor | J Med Chem 37: 2704-12 (1994) BindingDB Entry DOI: 10.7270/Q24748X6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50080550 ((2-Amino-4,5-dimethyl-thiophen-3-yl)-(3-trifluorom...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | 0.75 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Ferrara Curated by ChEMBL | Assay Description Allosteric enhancer activity at human adenosine A1 receptor expressed in CHO cell membranes assessed as [3H]NECA affinity constant at 1 uM (Kd = 0.87... | J Med Chem 57: 7673-86 (2014) Article DOI: 10.1021/jm5008853 BindingDB Entry DOI: 10.7270/Q2SQ91ZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50039689 (3-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-pu...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.790 | n/a | n/a | n/a | n/a | n/a |
University of South Florida Curated by ChEMBL | Assay Description Specific binding of [3H]-CPX to the A1-adenosine receptor | J Med Chem 37: 2704-12 (1994) BindingDB Entry DOI: 10.7270/Q24748X6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50095603 (4-[5-(8-Cyclohexyl-2,6-dioxo-1-propyl-1,2,6,7-tetr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.810 | n/a | n/a | n/a | n/a | n/a |
Deakin University Curated by ChEMBL | Assay Description Dissociation constant of [3H]-DPCPX binding to adenosine A1 receptor (AR) at 200 nM | J Med Chem 43: 4973-80 (2001) BindingDB Entry DOI: 10.7270/Q2S46R66 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50039678 (8-cyclopentyl-1,3-di[3-(4-fluorosulfonylphenylcarb...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.820 | n/a | n/a | n/a | n/a | n/a |
University of South Florida Curated by ChEMBL | Assay Description Specific binding of [3H]-CPX to the A1-adenosine receptor | J Med Chem 37: 2704-12 (1994) BindingDB Entry DOI: 10.7270/Q24748X6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50039691 (3-[3-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.860 | n/a | n/a | n/a | n/a | n/a |
University of South Florida Curated by ChEMBL | Assay Description Specific binding of [3H]-CPX to the A1-adenosine receptor | J Med Chem 37: 2704-12 (1994) BindingDB Entry DOI: 10.7270/Q24748X6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50253889 ((2-amino-4-((4-phenylpiperazin-1-yl)methyl)thiophe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a |
Dipartimento di Scienze Farmaceutiche Curated by ChEMBL | Assay Description Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cells | J Med Chem 51: 5875-9 (2008) Article DOI: 10.1021/jm800586p BindingDB Entry DOI: 10.7270/Q2PG1RJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50253891 ((2-amino-4-((4-(4-fluorophenyl)piperazin-1-yl)meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a |
Dipartimento di Scienze Farmaceutiche Curated by ChEMBL | Assay Description Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cells | J Med Chem 51: 5875-9 (2008) Article DOI: 10.1021/jm800586p BindingDB Entry DOI: 10.7270/Q2PG1RJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50253925 ((2-amino-4-((4-p-tolylpiperazin-1-yl)methyl)thioph...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a |
Dipartimento di Scienze Farmaceutiche Curated by ChEMBL | Assay Description Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cells | J Med Chem 51: 5875-9 (2008) Article DOI: 10.1021/jm800586p BindingDB Entry DOI: 10.7270/Q2PG1RJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50253928 ((2-amino-4-((4-(4-(trifluoromethyl)phenyl)piperazi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a |
Dipartimento di Scienze Farmaceutiche Curated by ChEMBL | Assay Description Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cells | J Med Chem 51: 5875-9 (2008) Article DOI: 10.1021/jm800586p BindingDB Entry DOI: 10.7270/Q2PG1RJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50039682 (4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-pu...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a |
University of South Florida Curated by ChEMBL | Assay Description Specific binding of [3H]-CPX to the A1-adenosine receptor | J Med Chem 37: 2704-12 (1994) BindingDB Entry DOI: 10.7270/Q24748X6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50253892 ((2-amino-4-((4-(4-chlorophenyl)piperazin-1-yl)meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a |
Dipartimento di Scienze Farmaceutiche Curated by ChEMBL | Assay Description Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cells | J Med Chem 51: 5875-9 (2008) Article DOI: 10.1021/jm800586p BindingDB Entry DOI: 10.7270/Q2PG1RJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50253890 ((2-amino-4-((4-benzylpiperazin-1-yl)methyl)thiophe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a |
Dipartimento di Scienze Farmaceutiche Curated by ChEMBL | Assay Description Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cells | J Med Chem 51: 5875-9 (2008) Article DOI: 10.1021/jm800586p BindingDB Entry DOI: 10.7270/Q2PG1RJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50039685 (3-[2-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a |
University of South Florida Curated by ChEMBL | Assay Description Specific binding of [3H]-CPX to the A1-adenosine receptor | J Med Chem 37: 2704-12 (1994) BindingDB Entry DOI: 10.7270/Q24748X6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50039697 (Bromo-acetic acid 2-(8-cyclopentyl-2,6-dioxo-1-pro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a |
University of South Florida Curated by ChEMBL | Assay Description Specific binding of [3H]-CPX to the A1-adenosine receptor | J Med Chem 37: 2704-12 (1994) BindingDB Entry DOI: 10.7270/Q24748X6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50080550 ((2-Amino-4,5-dimethyl-thiophen-3-yl)-(3-trifluorom...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a |
Dipartimento di Scienze Farmaceutiche Curated by ChEMBL | Assay Description Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cells | J Med Chem 51: 5875-9 (2008) Article DOI: 10.1021/jm800586p BindingDB Entry DOI: 10.7270/Q2PG1RJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50253888 ((2-amino-4-((4-cyclohexylpiperazin-1-yl)methyl)thi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a |
Dipartimento di Scienze Farmaceutiche Curated by ChEMBL | Assay Description Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cells | J Med Chem 51: 5875-9 (2008) Article DOI: 10.1021/jm800586p BindingDB Entry DOI: 10.7270/Q2PG1RJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50253308 ((2-amino-4-((4-(pyrimidin-2-yl)piperazin-1-yl)meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a |
Dipartimento di Scienze Farmaceutiche Curated by ChEMBL | Assay Description Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cells | J Med Chem 51: 5875-9 (2008) Article DOI: 10.1021/jm800586p BindingDB Entry DOI: 10.7270/Q2PG1RJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50253927 (4-(4-((5-amino-4-(4-chlorobenzoyl)thiophen-3-yl)me...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a |
Dipartimento di Scienze Farmaceutiche Curated by ChEMBL | Assay Description Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cells | J Med Chem 51: 5875-9 (2008) Article DOI: 10.1021/jm800586p BindingDB Entry DOI: 10.7270/Q2PG1RJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50253926 ((2-amino-4-((4-(benzo[d][1,3]dioxol-5-yl)piperazin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a |
Dipartimento di Scienze Farmaceutiche Curated by ChEMBL | Assay Description Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cells | J Med Chem 51: 5875-9 (2008) Article DOI: 10.1021/jm800586p BindingDB Entry DOI: 10.7270/Q2PG1RJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50253307 ((2-amino-4-((4-(pyridin-2-yl)piperazin-1-yl)methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a |
Dipartimento di Scienze Farmaceutiche Curated by ChEMBL | Assay Description Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cells | J Med Chem 51: 5875-9 (2008) Article DOI: 10.1021/jm800586p BindingDB Entry DOI: 10.7270/Q2PG1RJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50253852 ((2-amino-4-((4-methylpiperazin-1-yl)methyl)thiophe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a |
Dipartimento di Scienze Farmaceutiche Curated by ChEMBL | Assay Description Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cells | J Med Chem 51: 5875-9 (2008) Article DOI: 10.1021/jm800586p BindingDB Entry DOI: 10.7270/Q2PG1RJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50583640 (CHEMBL5075285) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to NLuc human A1 adenosine receptor expressed in HEK293-A cells in presence of 1 uM SLV320 by NanoBRET binding assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02067 BindingDB Entry DOI: 10.7270/Q2CV4NM3 | |||||||||||
More data for this Ligand-Target Pair |
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