BindingDB PrimarySearch

Found 5 hits of kd data for polymerid = 2210,49000820
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50333104 (CHEMBL389521 \| H-FGGFTGARKSARKLANQ-NH2 \| N/OFQ-NH2...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.0920	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Binding affinity to recombinant ORL1 receptor expressed in COS7 cells by saturation binding assay				Bioorg Med Chem 17: 7904-8 (2009) Article DOI: 10.1016/j.bmc.2009.10.026 BindingDB Entry DOI: 10.7270/Q28C9X65
Kyushu University Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50004178 (Nociceptin \| Nociceptin/orphanin FQ \| ORPHANIN FQ) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Binding affinity to human ORL1 receptor expressed in African green monkey COS7 cells assessed per mg protein after 90 mins by Scatchard plot analysis				Bioorg Med Chem 22: 5902-9 (2014) Article DOI: 10.1016/j.bmc.2014.09.018 BindingDB Entry DOI: 10.7270/Q2WD42BN
Kyushu University Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (MOUSE)	BDBM50411362 (CHEMBL437744) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.794	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Antagonist activity at NOP receptor in Swiss mouse vas deferens by [35S]GTP-gamma-S binding assay				Bioorg Med Chem 15: 4434-43 (2007) Article DOI: 10.1016/j.bmc.2007.04.026 BindingDB Entry DOI: 10.7270/Q22R3SVP
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50102836 (CHEMBL3343946) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Binding affinity to human ORL1 receptor expressed in African green monkey COS7 cells assessed per mg protein after 90 mins by Scatchard plot analysis				Bioorg Med Chem 22: 5902-9 (2014) Article DOI: 10.1016/j.bmc.2014.09.018 BindingDB Entry DOI: 10.7270/Q2WD42BN
Kyushu University Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (MOUSE)	BDBM50333103 (CHEMBL1631931) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.95	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phopshorylation administered for 15 mins before n...				J Med Chem 53: 8400-8408 (2010) Article DOI: 10.1021/jm101139f BindingDB Entry DOI: 10.7270/Q24Q7V77
TBA Curated by ChEMBL					More data for this Ligand-Target Pair