Found 77 hits of kd data for polymerid = 2272 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50386904
(CHEMBL2048526)Show SMILES COC(=O)[C@@H]1[C@H]2CC[C@@H](C[C@@H]1c1ccc(Cl)cc1)N2C\C=C\I |r,TLB:19:18:10.4.9:7.6| Show InChI InChI=1S/C18H21ClINO2/c1-23-18(22)17-15(12-3-5-13(19)6-4-12)11-14-7-8-16(17)21(14)10-2-9-20/h2-6,9,14-17H,7-8,10-11H2,1H3/b9-2+/t14-,15+,16+,17-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a |
Beijing Normal University
Curated by ChEMBL
| Assay Description
Binding affinity to DAT |
Bioorg Med Chem Lett 22: 4303-6 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.030
BindingDB Entry DOI: 10.7270/Q2XG9S50 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474026
(CHEMBL290901)Show SMILES COc1ccc(OC)c(\C=C\CN2CCN(CCOC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)c1 Show InChI InChI=1S/C30H34F2N2O3/c1-35-28-13-14-29(36-2)25(22-28)4-3-15-33-16-18-34(19-17-33)20-21-37-30(23-5-9-26(31)10-6-23)24-7-11-27(32)12-8-24/h3-14,22,30H,15-21H2,1-2H3/b4-3+ | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474064
(CHEMBL41237)Show SMILES Fc1ccc(\C=C\CN2CCN(CCOC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1 Show InChI InChI=1S/C28H29F3N2O/c29-25-9-3-22(4-10-25)2-1-15-32-16-18-33(19-17-32)20-21-34-28(23-5-11-26(30)12-6-23)24-7-13-27(31)14-8-24/h1-14,28H,15-21H2/b2-1+ | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474057
(CHEMBL41796)Show SMILES Fc1ccc(cc1)C(OCCN1CCN(C\C=C\c2ccccc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C28H30ClFN2O/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23/h1-15,28H,16-22H2/b7-4+ | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474027
(CHEMBL40415)Show SMILES Fc1ccc(cc1)C(OCCN1CCN(C\C=C\Cc2ccccc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C29H32F2N2O/c30-27-13-9-25(10-14-27)29(26-11-15-28(31)16-12-26)34-23-22-33-20-18-32(19-21-33)17-5-4-8-24-6-2-1-3-7-24/h1-7,9-16,29H,8,17-23H2/b5-4+ | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474039
(CHEMBL40797)Show SMILES Fc1ccc(CCCN2CCN(CCOC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1 Show InChI InChI=1S/C28H31F3N2O/c29-25-9-3-22(4-10-25)2-1-15-32-16-18-33(19-17-32)20-21-34-28(23-5-11-26(30)12-6-23)24-7-13-27(31)14-8-24/h3-14,28H,1-2,15-21H2 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM22199
(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-[(2E)-3-...)Show SMILES Fc1ccc(cc1)C(OCCN1CCN(C\C=C\c2ccccc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H30F2N2O/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23/h1-15,28H,16-22H2/b7-4+ | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 7.76 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM22199
(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-[(2E)-3-...)Show SMILES Fc1ccc(cc1)C(OCCN1CCN(C\C=C\c2ccccc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H30F2N2O/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23/h1-15,28H,16-22H2/b7-4+ | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 7.80 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474072
(CHEMBL38696)Show SMILES Fc1ccc(cc1)C(OCCN1CCN(CCCc2ccc(Cl)cc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H31ClF2N2O/c29-25-9-3-22(4-10-25)2-1-15-32-16-18-33(19-17-32)20-21-34-28(23-5-11-26(30)12-6-23)24-7-13-27(31)14-8-24/h3-14,28H,1-2,15-21H2 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 8.10 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474028
(CHEMBL41974)Show SMILES C(CN(Cc1ccccc1)c1ccccc1)CN1CCN(CCCc2ccccc2)CC1 Show InChI InChI=1S/C29H37N3/c1-4-12-27(13-5-1)16-10-19-30-22-24-31(25-23-30)20-11-21-32(29-17-8-3-9-18-29)26-28-14-6-2-7-15-28/h1-9,12-15,17-18H,10-11,16,19-26H2 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474028
(CHEMBL41974)Show SMILES C(CN(Cc1ccccc1)c1ccccc1)CN1CCN(CCCc2ccccc2)CC1 Show InChI InChI=1S/C29H37N3/c1-4-12-27(13-5-1)16-10-19-30-22-24-31(25-23-30)20-11-21-32(29-17-8-3-9-18-29)26-28-14-6-2-7-15-28/h1-9,12-15,17-18H,10-11,16,19-26H2 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474025
(CHEMBL38468)Show SMILES Fc1ccc(CN(CCCN2CCN(CCCc3ccccc3)CC2)c2ccccn2)cc1 Show InChI InChI=1S/C28H35FN4/c29-27-14-12-26(13-15-27)24-33(28-11-4-5-16-30-28)19-7-18-32-22-20-31(21-23-32)17-6-10-25-8-2-1-3-9-25/h1-5,8-9,11-16H,6-7,10,17-24H2 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474050
(CHEMBL289860)Show SMILES C(CCN1CCN(CCCc2ccccc2)CC1)CN(Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C30H39N3/c1-4-13-28(14-5-1)17-12-21-32-25-23-31(24-26-32)20-10-11-22-33(30-18-8-3-9-19-30)27-29-15-6-2-7-16-29/h1-9,13-16,18-19H,10-12,17,20-27H2 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474067
(CHEMBL38942)Show SMILES Fc1ccc(CN(CCCN2CCN(CCCc3ccccc3)CC2)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C29H35F2N3/c30-27-11-9-26(10-12-27)24-34(29-15-13-28(31)14-16-29)19-5-18-33-22-20-32(21-23-33)17-4-8-25-6-2-1-3-7-25/h1-3,6-7,9-16H,4-5,8,17-24H2 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474034
(CHEMBL440110)Show SMILES COc1ccc(CN(CCCN2CCN(CCCc3ccccc3)CC2)c2ccccn2)cc1 Show InChI InChI=1S/C29H38N4O/c1-34-28-15-13-27(14-16-28)25-33(29-12-5-6-17-30-29)20-8-19-32-23-21-31(22-24-32)18-7-11-26-9-3-2-4-10-26/h2-6,9-10,12-17H,7-8,11,18-25H2,1H3 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474038
(CHEMBL38773)Show SMILES Fc1ccc(\C=C\CN2CCN(CCOC(c3ccccc3)c3ccccc3)CC2)cc1 Show InChI InChI=1S/C28H31FN2O/c29-27-15-13-24(14-16-27)8-7-17-30-18-20-31(21-19-30)22-23-32-28(25-9-3-1-4-10-25)26-11-5-2-6-12-26/h1-16,28H,17-23H2/b8-7+ | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474069
(CHEMBL41606)Show SMILES Fc1ccc(cc1)C(OCCN1CCN(CCCc2ccccc2)CC1)c1ccccc1 Show InChI InChI=1S/C28H33FN2O/c29-27-15-13-26(14-16-27)28(25-11-5-2-6-12-25)32-23-22-31-20-18-30(19-21-31)17-7-10-24-8-3-1-4-9-24/h1-6,8-9,11-16,28H,7,10,17-23H2 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474056
(CHEMBL41797)Show SMILES Fc1ccc(cc1)C(OCCN1CCN(C\C=C\c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H29ClF2N2O/c29-25-9-3-22(4-10-25)2-1-15-32-16-18-33(19-17-32)20-21-34-28(23-5-11-26(30)12-6-23)24-7-13-27(31)14-8-24/h1-14,28H,15-21H2/b2-1+ | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474044
(CHEMBL39890)Show SMILES Fc1ccc(\C=C\CN2CCN(CCOC(c3ccccc3)c3ccc(F)cc3)CC2)cc1 Show InChI InChI=1S/C28H30F2N2O/c29-26-12-8-23(9-13-26)5-4-16-31-17-19-32(20-18-31)21-22-33-28(24-6-2-1-3-7-24)25-10-14-27(30)15-11-25/h1-15,28H,16-22H2/b5-4+ | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50028094
((1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-te...)Show SMILES CN[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C17H17Cl2N/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11/h2-6,8,10,12,17,20H,7,9H2,1H3/t12-,17-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
PubMed
| n/a | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a |
Hong Kong University of Science and Technology
Curated by ChEMBL
| Assay Description
Equilibrium dissociation constant (KD) for Competitive binding between [3H]WIN-35428 and the compound at human transporter-hDAT |
Bioorg Med Chem Lett 8: 487-92 (1999)
BindingDB Entry DOI: 10.7270/Q2F76D26 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474055
(CHEMBL41022)Show SMILES O=C(CCCN1CCN(CCCc2ccccc2)CC1)N(Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C30H37N3O/c34-30(33(29-17-8-3-9-18-29)26-28-14-6-2-7-15-28)19-11-21-32-24-22-31(23-25-32)20-10-16-27-12-4-1-5-13-27/h1-9,12-15,17-18H,10-11,16,19-26H2 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474029
(CHEMBL288823)Show SMILES Fc1ccc(CCCN2CCN(CCOC(c3ccccc3)c3ccc(F)cc3)CC2)cc1 Show InChI InChI=1S/C28H32F2N2O/c29-26-12-8-23(9-13-26)5-4-16-31-17-19-32(20-18-31)21-22-33-28(24-6-2-1-3-7-24)25-10-14-27(30)15-11-25/h1-3,6-15,28H,4-5,16-22H2 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474047
(CHEMBL290536)Show SMILES C(CCN(Cc1ccccc1)c1ccccc1)CCN1CCN(CCCc2ccccc2)CC1 Show InChI InChI=1S/C31H41N3/c1-5-14-29(15-6-1)18-13-22-33-26-24-32(25-27-33)21-11-4-12-23-34(31-19-9-3-10-20-31)28-30-16-7-2-8-17-30/h1-3,5-10,14-17,19-20H,4,11-13,18,21-28H2 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474059
(CHEMBL39282)Show SMILES Fc1ccc(cc1)C(OCCN1CCN(C\C=C\c2ccccc2)CC1)c1ccccc1 Show InChI InChI=1S/C28H31FN2O/c29-27-15-13-26(14-16-27)28(25-11-5-2-6-12-25)32-23-22-31-20-18-30(19-21-31)17-7-10-24-8-3-1-4-9-24/h1-16,28H,17-23H2/b10-7+ | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474031
(CHEMBL290267)Show SMILES COc1ccc(cc1)C(OCCN1CCN(C\C=C\c2ccccc2)CC1)c1ccccc1 Show InChI InChI=1S/C29H34N2O2/c1-32-28-16-14-27(15-17-28)29(26-12-6-3-7-13-26)33-24-23-31-21-19-30(20-22-31)18-8-11-25-9-4-2-5-10-25/h2-17,29H,18-24H2,1H3/b11-8+ | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474073
(CHEMBL288863)Show SMILES Clc1ccc(cc1)C(OCCN1CCN(C\C=C\c2ccccc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C28H30Cl2N2O/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23/h1-15,28H,16-22H2/b7-4+ | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474041
(CHEMBL288914)Show SMILES Fc1ccc(CCCN2CCN(CCOC(c3ccccc3)c3ccccc3)CC2)cc1 Show InChI InChI=1S/C28H33FN2O/c29-27-15-13-24(14-16-27)8-7-17-30-18-20-31(21-19-30)22-23-32-28(25-9-3-1-4-10-25)26-11-5-2-6-12-26/h1-6,9-16,28H,7-8,17-23H2 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474045
(CHEMBL40529)Show SMILES Cc1ccc(\C=C\CN2CCN(CCOC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1 Show InChI InChI=1S/C29H32F2N2O/c1-23-4-6-24(7-5-23)3-2-16-32-17-19-33(20-18-32)21-22-34-29(25-8-12-27(30)13-9-25)26-10-14-28(31)15-11-26/h2-15,29H,16-22H2,1H3/b3-2+ | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474042
(CHEMBL290365)Show SMILES Fc1ccc(CN(CCN2CCN(CCCc3ccccc3)CC2)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C28H33F2N3/c29-26-10-8-25(9-11-26)23-33(28-14-12-27(30)13-15-28)22-21-32-19-17-31(18-20-32)16-4-7-24-5-2-1-3-6-24/h1-3,5-6,8-15H,4,7,16-23H2 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474046
(CHEMBL41027)Show SMILES O=C(CCCCN1CCN(CCCc2ccccc2)CC1)N(Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H39N3O/c35-31(34(30-18-8-3-9-19-30)27-29-15-6-2-7-16-29)20-10-11-21-32-23-25-33(26-24-32)22-12-17-28-13-4-1-5-14-28/h1-9,13-16,18-19H,10-12,17,20-27H2 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474062
(CHEMBL416433)Show SMILES Fc1ccc(CN(CCN2CCN(CCCc3ccccc3)CC2)c2ccccn2)cc1 Show InChI InChI=1S/C27H33FN4/c28-26-13-11-25(12-14-26)23-32(27-10-4-5-15-29-27)22-21-31-19-17-30(18-20-31)16-6-9-24-7-2-1-3-8-24/h1-5,7-8,10-15H,6,9,16-23H2 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50083200
(1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-[(E)...)Show SMILES COc1ccc(\C=C\CN2CCN(CCOC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1 Show InChI InChI=1S/C29H32F2N2O2/c1-34-28-14-4-23(5-15-28)3-2-16-32-17-19-33(20-18-32)21-22-35-29(24-6-10-26(30)11-7-24)25-8-12-27(31)13-9-25/h2-15,29H,16-22H2,1H3/b3-2+ | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474048
(CHEMBL40240)Show SMILES Fc1ccc(cc1)C(OCCN1CCN(C\C=C\c2ccccc2)CC1)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C28H29Cl2FN2O/c29-24-10-13-26(27(30)21-24)28(23-8-11-25(31)12-9-23)34-20-19-33-17-15-32(16-18-33)14-4-7-22-5-2-1-3-6-22/h1-13,21,28H,14-20H2/b7-4+ | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50069453
((1R,2R)-3-Dimethylamino-2-naphthalen-2-yl-1-phenyl...)Show SMILES CN(C)C[C@H]([C@@H](O)c1ccccc1)c1ccc2ccccc2c1 Show InChI InChI=1S/C21H23NO/c1-22(2)15-20(21(23)17-9-4-3-5-10-17)19-13-12-16-8-6-7-11-18(16)14-19/h3-14,20-21,23H,15H2,1-2H3/t20-,21-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a |
Hong Kong University of Science and Technology
Curated by ChEMBL
| Assay Description
Equilibrium dissociation constant (KD) for Competitive binding between [3H]WIN-35428 and the compound at human transporter-hDAT |
Bioorg Med Chem Lett 8: 487-92 (1999)
BindingDB Entry DOI: 10.7270/Q2F76D26 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474065
(CHEMBL43125)Show SMILES C(CN1CCN(CCN(Cc2ccccc2)c2ccccn2)CC1)Cc1ccccc1 Show InChI InChI=1S/C27H34N4/c1-3-10-25(11-4-1)14-9-17-29-18-20-30(21-19-29)22-23-31(27-15-7-8-16-28-27)24-26-12-5-2-6-13-26/h1-8,10-13,15-16H,9,14,17-24H2 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 91 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474071
(CHEMBL288109)Show SMILES Fc1ccc(cc1)C(OCCN1CCN(Cc2ccccc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C26H28F2N2O/c27-24-10-6-22(7-11-24)26(23-8-12-25(28)13-9-23)31-19-18-29-14-16-30(17-15-29)20-21-4-2-1-3-5-21/h1-13,26H,14-20H2 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474049
(CHEMBL40961)Show SMILES C(CN(Cc1ccccc1)c1ccccn1)CN1CCN(CCCc2ccccc2)CC1 Show InChI InChI=1S/C28H36N4/c1-3-11-26(12-4-1)15-9-18-30-21-23-31(24-22-30)19-10-20-32(28-16-7-8-17-29-28)25-27-13-5-2-6-14-27/h1-8,11-14,16-17H,9-10,15,18-25H2 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 107 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474049
(CHEMBL40961)Show SMILES C(CN(Cc1ccccc1)c1ccccn1)CN1CCN(CCCc2ccccc2)CC1 Show InChI InChI=1S/C28H36N4/c1-3-11-26(12-4-1)15-9-18-30-21-23-31(24-22-30)19-10-20-32(28-16-7-8-17-29-28)25-27-13-5-2-6-14-27/h1-8,11-14,16-17H,9-10,15,18-25H2 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 107 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474043
(CHEMBL40429)Show SMILES Cc1ccc(cc1)C(OCCN1CCN(C\C=C\c2ccccc2)CC1)c1ccccc1 Show InChI InChI=1S/C29H34N2O/c1-25-14-16-28(17-15-25)29(27-12-6-3-7-13-27)32-24-23-31-21-19-30(20-22-31)18-8-11-26-9-4-2-5-10-26/h2-17,29H,18-24H2,1H3/b11-8+ | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 112 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474063
(CHEMBL41390)Show SMILES COc1cccc(c1)C(OCCN1CCN(C\C=C\c2ccccc2)CC1)c1cccc(Br)c1 Show InChI InChI=1S/C29H33BrN2O2/c1-33-28-14-6-12-26(23-28)29(25-11-5-13-27(30)22-25)34-21-20-32-18-16-31(17-19-32)15-7-10-24-8-3-2-4-9-24/h2-14,22-23,29H,15-21H2,1H3/b10-7+ | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 132 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50069448
((1R,2R)-3-Amino-2-naphthalen-2-yl-1-phenyl-propan-...)Show InChI InChI=1S/C19H19NO/c20-13-18(19(21)15-7-2-1-3-8-15)17-11-10-14-6-4-5-9-16(14)12-17/h1-12,18-19,21H,13,20H2/t18-,19-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a |
Hong Kong University of Science and Technology
Curated by ChEMBL
| Assay Description
Equilibrium dissociation constant (KD) for Competitive binding between [3H]WIN-35428 and the compound at human transporter-hDAT |
Bioorg Med Chem Lett 8: 487-92 (1999)
BindingDB Entry DOI: 10.7270/Q2F76D26 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50025691
(2-(2-Ethoxy-phenoxymethyl)-morpholine | 2-(2-Ethox...)Show InChI InChI=1S/C13H19NO3/c1-2-15-12-5-3-4-6-13(12)17-10-11-9-14-7-8-16-11/h3-6,11,14H,2,7-10H2,1H3 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
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| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | 155 | n/a | n/a | n/a | n/a | n/a |
Hong Kong University of Science and Technology
Curated by ChEMBL
| Assay Description
Equilibrium dissociation constant (KD) for Competitive binding between [3H]WIN-35428 and the compound at human transporter-hDAT |
Bioorg Med Chem Lett 8: 487-92 (1999)
BindingDB Entry DOI: 10.7270/Q2F76D26 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50459929
(CHEMBL4228171)Show SMILES CNC[C@H]([C@@H](O)c1ccccc1)c1ccc2ccccc2c1 |r| Show InChI InChI=1S/C20H21NO/c1-21-14-19(20(22)16-8-3-2-4-9-16)18-12-11-15-7-5-6-10-17(15)13-18/h2-13,19-22H,14H2,1H3/t19-,20-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a |
Biocon Bristol-Myers Squibb R&D Centre
Curated by ChEMBL
| Assay Description
Binding affinity to human DAT expressed in HEK293 cells after 60 mins in presence of [3H]imipramine by liquid scintillation counting |
J Med Chem 61: 2133-2165 (2018)
Article DOI: 10.1021/acs.jmedchem.6b01827
BindingDB Entry DOI: 10.7270/Q2BV7K8M |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474052
(CHEMBL40358)Show SMILES COc1ccc(CN(CCN2CCN(CCCc3ccccc3)CC2)c2ccccn2)cc1 Show InChI InChI=1S/C28H36N4O/c1-33-27-14-12-26(13-15-27)24-32(28-11-5-6-16-29-28)23-22-31-20-18-30(19-21-31)17-7-10-25-8-3-2-4-9-25/h2-6,8-9,11-16H,7,10,17-24H2,1H3 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 219 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474040
(CHEMBL42150)Show SMILES C(CN1CCN(CCN(Cc2ccccc2)c2ccccc2)CC1)Cc1ccccc1 Show InChI InChI=1S/C28H35N3/c1-4-11-26(12-5-1)15-10-18-29-19-21-30(22-20-29)23-24-31(28-16-8-3-9-17-28)25-27-13-6-2-7-14-27/h1-9,11-14,16-17H,10,15,18-25H2 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 219 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50069444
((1R,2R)-3-Amino-2-phenyl-1-(2,4,6-trimethyl-phenyl...)Show SMILES Cc1cc(C)c([C@H](O)[C@@H](CN)c2ccccc2)c(C)c1 Show InChI InChI=1S/C18H23NO/c1-12-9-13(2)17(14(3)10-12)18(20)16(11-19)15-7-5-4-6-8-15/h4-10,16,18,20H,11,19H2,1-3H3/t16-,18+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a |
Hong Kong University of Science and Technology
Curated by ChEMBL
| Assay Description
Equilibrium dissociation constant (KD) for Competitive binding between [3H]WIN-35428 and the compound at human transporter-hDAT |
Bioorg Med Chem Lett 8: 487-92 (1999)
BindingDB Entry DOI: 10.7270/Q2F76D26 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50069449
((2R,3R)-1-Dimethylamino-4,4-dimethyl-2-naphthalen-...)Show SMILES CN(C)C[C@H]([C@@H](O)C(C)(C)C)c1ccc2ccccc2c1 Show InChI InChI=1S/C19H27NO/c1-19(2,3)18(21)17(13-20(4)5)16-11-10-14-8-6-7-9-15(14)12-16/h6-12,17-18,21H,13H2,1-5H3/t17-,18+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a |
Hong Kong University of Science and Technology
Curated by ChEMBL
| Assay Description
Equilibrium dissociation constant (KD) for Competitive binding between [3H]WIN-35428 and the compound at human transporter-hDAT |
Bioorg Med Chem Lett 8: 487-92 (1999)
BindingDB Entry DOI: 10.7270/Q2F76D26 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50069447
(1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3-e...)Show SMILES CCc1nn(CCCN2CCN(CC2)c2cccc(Cl)c2)c(=O)n1CCOc1ccccc1 Show InChI InChI=1S/C25H32ClN5O2/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22/h3-6,8-11,20H,2,7,12-19H2,1H3 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| DrugBank
PubMed
| n/a | n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a |
Hong Kong University of Science and Technology
Curated by ChEMBL
| Assay Description
Equilibrium dissociation constant (KD) for Competitive binding between [3H]WIN-35428 and the compound at human transporter-hDAT |
Bioorg Med Chem Lett 8: 487-92 (1999)
BindingDB Entry DOI: 10.7270/Q2F76D26 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM22199
(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-[(2E)-3-...)Show SMILES Fc1ccc(cc1)C(OCCN1CCN(C\C=C\c2ccccc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H30F2N2O/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23/h1-15,28H,16-22H2/b7-4+ | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 407 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50474053
(CHEMBL415886)Show SMILES Fc1ccc(cc1)C(OCCN1CCN(CC1)C(=O)\C=C\c1ccc(Cl)cc1)c1ccc(F)cc1 Show InChI InChI=1S/C28H27ClF2N2O2/c29-24-8-1-21(2-9-24)3-14-27(34)33-17-15-32(16-18-33)19-20-35-28(22-4-10-25(30)11-5-22)23-6-12-26(31)13-7-23/h1-14,28H,15-20H2/b14-3+ | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 427 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia
Curated by ChEMBL
| Assay Description
Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells |
J Med Chem 45: 1577-84 (2002)
Article DOI: 10.1021/jm011007+
BindingDB Entry DOI: 10.7270/Q29026JT |
More data for this
Ligand-Target Pair | |
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