Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monoglyceride lipase (Homo sapiens (Human)) | BDBM150300 (US8987247, 1) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV US Patent | Assay Description The ThermoFluor (TF) assay is a 384-well microplate-based binding assay that measures thermal stability of proteins1,2. The experiments were carried ... | US Patent US8987247 (2015) BindingDB Entry DOI: 10.7270/Q2V40SXC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Homo sapiens (Human)) | BDBM50567001 (CHEMBL4873898) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to human His-tagged MAGL assessed as dissociation constant by surface plasmon resonance assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00432 BindingDB Entry DOI: 10.7270/Q2M90DDN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Monoglyceride lipase (Homo sapiens (Human)) | BDBM50569386 (CHEMBL1356127) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to MAGL (unknown origin) by SPR analysis | Citation and Details Article DOI: 10.1016/j.bmcl.2021.127986 BindingDB Entry DOI: 10.7270/Q2D222D0 | |||||||||||
More data for this Ligand-Target Pair |