Found 8 hits of kd data for polymerid = 50001148,50004925 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Midkine
(Homo sapiens (Human)) | BDBM50364350
(CHEMBL1950106)Show SMILES CC(=O)N[C@@H]1[C@@H](O)[C@@H](OS([O-])(=O)=O)[C@@H](COS([O-])(=O)=O)O[C@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@@H]2[C@@H](NC(C)=O)[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](OCCNC(=O)CCOCCOCCOCCOCCNC(=O)CCCC[C@@H]4SC[C@@H]5NC(=O)N[C@H]45)O[C@@H]3C(O)=O)O[C@H](COS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)O[C@@H]1C(O)=O |r| Show InChI InChI=1S/C51H84N6O42S5/c1-22(58)54-31-33(62)38(98-103(78,79)80)25(19-89-101(72,73)74)91-47(31)94-42-35(64)37(66)50(97-44(42)46(69)70)93-40-32(55-23(2)59)48(92-26(20-90-102(75,76)77)39(40)99-104(81,82)83)95-41-34(63)36(65)49(96-43(41)45(67)68)88-12-9-53-29(61)7-10-84-13-15-86-17-18-87-16-14-85-11-8-52-28(60)6-4-3-5-27-30-24(21-100-27)56-51(71)57-30/h24-27,30-44,47-50,62-66H,3-21H2,1-2H3,(H,52,60)(H,53,61)(H,54,58)(H,55,59)(H,67,68)(H,69,70)(H2,56,57,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)(H,81,82,83)/p-4/t24-,25+,26+,27-,30-,31+,32+,33+,34+,35+,36+,37+,38-,39-,40+,41-,42-,43-,44-,47-,48-,49+,50+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.62 | n/a | n/a | n/a | n/a | n/a |
Tottori University
Curated by ChEMBL
| Assay Description
Binding affinity to recombinant midkine after 3 mins |
Bioorg Med Chem Lett 22: 1371-4 (2012)
Article DOI: 10.1016/j.bmcl.2011.12.054
BindingDB Entry DOI: 10.7270/Q2MP53R3 |
More data for this
Ligand-Target Pair | |
Midkine
(Homo sapiens (Human)) | BDBM50364352
(CHEMBL1950108)Show SMILES CC(=O)N[C@@H]1[C@@H](O)[C@@H](OS([O-])(=O)=O)[C@@H](COS([O-])(=O)=O)O[C@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@@H]2[C@@H](NC(C)=O)[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](OCCNC(=O)CCOCCOCCOCCOCCNC(=O)CCCC[C@@H]4SC[C@@H]5NC(=O)N[C@H]45)O[C@@H]3C(O)=O)O[C@H](CO)[C@@H]2OS([O-])(=O)=O)O[C@@H]1C(O)=O |r| Show InChI InChI=1S/C51H84N6O39S4/c1-22(59)54-31-33(63)38(95-99(76,77)78)26(20-87-98(73,74)75)89-47(31)91-42-35(65)37(67)50(94-44(42)46(70)71)90-40-32(55-23(2)60)48(88-25(19-58)39(40)96-100(79,80)81)92-41-34(64)36(66)49(93-43(41)45(68)69)86-12-9-53-29(62)7-10-82-13-15-84-17-18-85-16-14-83-11-8-52-28(61)6-4-3-5-27-30-24(21-97-27)56-51(72)57-30/h24-27,30-44,47-50,58,63-67H,3-21H2,1-2H3,(H,52,61)(H,53,62)(H,54,59)(H,55,60)(H,68,69)(H,70,71)(H2,56,57,72)(H,73,74,75)(H,76,77,78)(H,79,80,81)/p-3/t24-,25+,26+,27-,30-,31+,32+,33+,34+,35+,36+,37+,38-,39-,40+,41-,42-,43-,44-,47-,48-,49+,50+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 11.6 | n/a | n/a | n/a | n/a | n/a |
Tottori University
Curated by ChEMBL
| Assay Description
Binding affinity to recombinant midkine after 3 mins |
Bioorg Med Chem Lett 22: 1371-4 (2012)
Article DOI: 10.1016/j.bmcl.2011.12.054
BindingDB Entry DOI: 10.7270/Q2MP53R3 |
More data for this
Ligand-Target Pair | |
Midkine
(Homo sapiens (Human)) | BDBM50364351
(CHEMBL1950107)Show SMILES CC(=O)N[C@@H]1[C@@H](O)[C@@H](OS([O-])(=O)=O)[C@@H](CO)O[C@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@@H]2[C@@H](NC(C)=O)[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](OCCNC(=O)CCOCCOCCOCCOCCNC(=O)CCCC[C@@H]4SC[C@@H]5NC(=O)N[C@H]45)O[C@@H]3C(O)=O)O[C@H](CO)[C@@H]2OS([O-])(=O)=O)O[C@@H]1C(O)=O |r| Show InChI InChI=1S/C51H84N6O36S3/c1-22(60)54-31-33(64)38(92-95(74,75)76)25(19-58)85-47(31)88-42-35(66)37(68)50(91-44(42)46(71)72)87-40-32(55-23(2)61)48(86-26(20-59)39(40)93-96(77,78)79)89-41-34(65)36(67)49(90-43(41)45(69)70)84-12-9-53-29(63)7-10-80-13-15-82-17-18-83-16-14-81-11-8-52-28(62)6-4-3-5-27-30-24(21-94-27)56-51(73)57-30/h24-27,30-44,47-50,58-59,64-68H,3-21H2,1-2H3,(H,52,62)(H,53,63)(H,54,60)(H,55,61)(H,69,70)(H,71,72)(H2,56,57,73)(H,74,75,76)(H,77,78,79)/p-2/t24-,25+,26+,27-,30-,31+,32+,33+,34+,35+,36+,37+,38-,39-,40+,41-,42-,43-,44-,47-,48-,49+,50+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 17.8 | n/a | n/a | n/a | n/a | n/a |
Tottori University
Curated by ChEMBL
| Assay Description
Binding affinity to recombinant midkine after 3 mins |
Bioorg Med Chem Lett 22: 1371-4 (2012)
Article DOI: 10.1016/j.bmcl.2011.12.054
BindingDB Entry DOI: 10.7270/Q2MP53R3 |
More data for this
Ligand-Target Pair | |
Midkine
(Homo sapiens (Human)) | BDBM50529728
(CHEMBL4540967)Show SMILES [H][C@]1(O[C@@H]2O[C@H](C(O)=O)[C@@]([H])(O[C@@H]3O[C@H](COS(O)(=O)=O)[C@@H](O)[C@]([H])(O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)C(O)=O)[C@H]3NC(C)=O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](COS(O)(=O)=O)O[C@@H](OCCCCCCN=[N+]=[N-])[C@@H]1NC(C)=O |r| Show InChI InChI=1S/C34H55N5O29S2/c1-11(40)37-15-24(17(42)13(9-60-69(53,54)55)62-31(15)59-8-6-4-3-5-7-36-39-35)64-34-23(48)21(46)26(28(68-34)30(51)52)66-32-16(38-12(2)41)25(18(43)14(63-32)10-61-70(56,57)58)65-33-22(47)19(44)20(45)27(67-33)29(49)50/h13-28,31-34,42-48H,3-10H2,1-2H3,(H,37,40)(H,38,41)(H,49,50)(H,51,52)(H,53,54,55)(H,56,57,58)/t13-,14-,15-,16-,17-,18-,19+,20+,21-,22-,23-,24-,25-,26+,27+,28+,31-,32+,33-,34-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a |
Peking University
Curated by ChEMBL
| Assay Description
Binding affinity to MDK (unknown origin) by SPR assay |
Eur J Med Chem 163: 583-596 (2019)
Article DOI: 10.1016/j.ejmech.2018.12.004
BindingDB Entry DOI: 10.7270/Q2K64NJH |
More data for this
Ligand-Target Pair | |
Midkine
(Homo sapiens (Human)) | BDBM50529728
(CHEMBL4540967)Show SMILES [H][C@]1(O[C@@H]2O[C@H](C(O)=O)[C@@]([H])(O[C@@H]3O[C@H](COS(O)(=O)=O)[C@@H](O)[C@]([H])(O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)C(O)=O)[C@H]3NC(C)=O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](COS(O)(=O)=O)O[C@@H](OCCCCCCN=[N+]=[N-])[C@@H]1NC(C)=O |r| Show InChI InChI=1S/C34H55N5O29S2/c1-11(40)37-15-24(17(42)13(9-60-69(53,54)55)62-31(15)59-8-6-4-3-5-7-36-39-35)64-34-23(48)21(46)26(28(68-34)30(51)52)66-32-16(38-12(2)41)25(18(43)14(63-32)10-61-70(56,57)58)65-33-22(47)19(44)20(45)27(67-33)29(49)50/h13-28,31-34,42-48H,3-10H2,1-2H3,(H,37,40)(H,38,41)(H,49,50)(H,51,52)(H,53,54,55)(H,56,57,58)/t13-,14-,15-,16-,17-,18-,19+,20+,21-,22-,23-,24-,25-,26+,27+,28+,31-,32+,33-,34-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a |
Peking University
Curated by ChEMBL
| Assay Description
Binding affinity to MDK (unknown origin) by SPR assay |
Eur J Med Chem 163: 583-596 (2019)
Article DOI: 10.1016/j.ejmech.2018.12.004
BindingDB Entry DOI: 10.7270/Q2K64NJH |
More data for this
Ligand-Target Pair | |
Midkine
(Homo sapiens (Human)) | BDBM50529729
(CHEMBL4436421)Show SMILES [H][C@@]1(O[C@@H]2O[C@H](C(O)=O)[C@@]([H])(O[C@@H]3O[C@H](COS(O)(=O)=O)[C@H](OS(O)(=O)=O)[C@]([H])(O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)C(O)=O)[C@H]3NC(C)=O)[C@H](O)[C@H]2O)[C@@H](NC(C)=O)[C@H](OCCCCCCN=[N+]=[N-])O[C@H](COS(O)(=O)=O)[C@@H]1OS(O)(=O)=O |r| Show InChI InChI=1S/C34H55N5O35S4/c1-11(40)37-15-24(22(73-77(57,58)59)13(9-64-75(51,52)53)66-31(15)63-8-6-4-3-5-7-36-39-35)68-34-21(46)19(44)26(28(72-34)30(49)50)70-32-16(38-12(2)41)25(69-33-20(45)17(42)18(43)27(71-33)29(47)48)23(74-78(60,61)62)14(67-32)10-65-76(54,55)56/h13-28,31-34,42-46H,3-10H2,1-2H3,(H,37,40)(H,38,41)(H,47,48)(H,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)/t13-,14-,15-,16-,17+,18+,19-,20-,21-,22+,23+,24-,25-,26+,27+,28+,31-,32+,33-,34-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a |
Peking University
Curated by ChEMBL
| Assay Description
Binding affinity to MDK (unknown origin) by SPR assay |
Eur J Med Chem 163: 583-596 (2019)
Article DOI: 10.1016/j.ejmech.2018.12.004
BindingDB Entry DOI: 10.7270/Q2K64NJH |
More data for this
Ligand-Target Pair | |
Midkine
(Homo sapiens (Human)) | BDBM50529729
(CHEMBL4436421)Show SMILES [H][C@@]1(O[C@@H]2O[C@H](C(O)=O)[C@@]([H])(O[C@@H]3O[C@H](COS(O)(=O)=O)[C@H](OS(O)(=O)=O)[C@]([H])(O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)C(O)=O)[C@H]3NC(C)=O)[C@H](O)[C@H]2O)[C@@H](NC(C)=O)[C@H](OCCCCCCN=[N+]=[N-])O[C@H](COS(O)(=O)=O)[C@@H]1OS(O)(=O)=O |r| Show InChI InChI=1S/C34H55N5O35S4/c1-11(40)37-15-24(22(73-77(57,58)59)13(9-64-75(51,52)53)66-31(15)63-8-6-4-3-5-7-36-39-35)68-34-21(46)19(44)26(28(72-34)30(49)50)70-32-16(38-12(2)41)25(69-33-20(45)17(42)18(43)27(71-33)29(47)48)23(74-78(60,61)62)14(67-32)10-65-76(54,55)56/h13-28,31-34,42-46H,3-10H2,1-2H3,(H,37,40)(H,38,41)(H,47,48)(H,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)/t13-,14-,15-,16-,17+,18+,19-,20-,21-,22+,23+,24-,25-,26+,27+,28+,31-,32+,33-,34-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a |
Peking University
Curated by ChEMBL
| Assay Description
Binding affinity to MDK (unknown origin) by SPR assay |
Eur J Med Chem 163: 583-596 (2019)
Article DOI: 10.1016/j.ejmech.2018.12.004
BindingDB Entry DOI: 10.7270/Q2K64NJH |
More data for this
Ligand-Target Pair | |
Midkine
(Homo sapiens (Human)) | BDBM50364349
(CHEMBL1950105)Show SMILES CC(=O)N[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H](O)[C@@H](CO)O[C@@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](OCCNC(=O)CCOCCOCCOCCOCCNC(=O)CCCC[C@@H]4SC[C@@H]5NC(=O)N[C@H]45)O[C@@H]3C(O)=O)[C@@H]2NC(C)=O)O[C@@H]1C(O)=O |r| Show InChI InChI=1S/C51H84N6O30S/c1-22(60)54-31-35(66)33(64)25(19-58)81-47(31)84-42-37(68)39(70)50(87-44(42)46(73)74)83-40-32(55-23(2)61)48(82-26(20-59)34(40)65)85-41-36(67)38(69)49(86-43(41)45(71)72)80-12-9-53-29(63)7-10-76-13-15-78-17-18-79-16-14-77-11-8-52-28(62)6-4-3-5-27-30-24(21-88-27)56-51(75)57-30/h24-27,30-44,47-50,58-59,64-70H,3-21H2,1-2H3,(H,52,62)(H,53,63)(H,54,60)(H,55,61)(H,71,72)(H,73,74)(H2,56,57,75)/t24-,25+,26+,27-,30-,31+,32+,33-,34-,35+,36+,37+,38+,39+,40+,41-,42-,43-,44-,47-,48-,49+,50+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.03E+3 | n/a | n/a | n/a | n/a | n/a |
Tottori University
Curated by ChEMBL
| Assay Description
Binding affinity to recombinant midkine after 3 mins |
Bioorg Med Chem Lett 22: 1371-4 (2012)
Article DOI: 10.1016/j.bmcl.2011.12.054
BindingDB Entry DOI: 10.7270/Q2MP53R3 |
More data for this
Ligand-Target Pair | |
Search and Browse
