BindingDB PrimarySearch

Found 34 hits of kd data for polymerid = 50006449
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50539801 (CHEMBL4648912 \| US11840533, Compound 70) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to human partial length SMARCA4 (A1448 to S1575 residues) expressed in bacterial expression system by BROMOscan assay				J Med Chem 63: 7186-7210 (2020) Article DOI: 10.1021/acs.jmedchem.0c00456 BindingDB Entry DOI: 10.7270/Q2PK0KPP
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM394530 ((R)-1-(4-(3-amino-6-(2- \| US10308614, Example 131) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00662 BindingDB Entry DOI: 10.7270/Q2TB1BX4
TBA					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50158688 (CHEMBL3752911) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00662 BindingDB Entry DOI: 10.7270/Q2TB1BX4
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Transcription activator BRG1 (Homo sapiens (Human))	BDBM394399 (US10308614, Example 1 \| tert-butyl 4-(3-amino-6-(2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to SMARCA4 (unknown origin) by ITC analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01242 BindingDB Entry DOI: 10.7270/Q2FR017S
TBA					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM394530 ((R)-1-(4-(3-amino-6-(2- \| US10308614, Example 131) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00662 BindingDB Entry DOI: 10.7270/Q2TB1BX4
TBA					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50182280 (CHEMBL3819245) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to human SMARCA4 expressed in BL21 (DE3)-R3-BirA cells by isothermal titration calorimetry				J Med Chem 59: 4800-11 (2016) Article DOI: 10.1021/acs.jmedchem.6b00012 BindingDB Entry DOI: 10.7270/Q2G44S62
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50549126 (CHEMBL4793170) Show SMILES Nc1nnc(cc1N1CCC(O)CC1)-c1ccccc1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to SMARCA4 (unknown origin) by ITC analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01242 BindingDB Entry DOI: 10.7270/Q2FR017S
TBA					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM394583 (2-(6-amino-5-phenylpyridazin-3-yl)phenol \| US10308...) Show SMILES Nc1nnc(cc1-c1ccccc1)-c1ccccc1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00662 BindingDB Entry DOI: 10.7270/Q2TB1BX4
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Transcription activator BRG1 (Homo sapiens (Human))	BDBM394406 (2-(6-amino-5-(piperazin- \| US10308614, Example 7) Show SMILES Nc1nnc(cc1N1CCNCC1)-c1ccccc1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to SMARCA4 (unknown origin) by ITC analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01242 BindingDB Entry DOI: 10.7270/Q2FR017S
TBA					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM394583 (2-(6-amino-5-phenylpyridazin-3-yl)phenol \| US10308...) Show SMILES Nc1nnc(cc1-c1ccccc1)-c1ccccc1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00662 BindingDB Entry DOI: 10.7270/Q2TB1BX4
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50158688 (CHEMBL3752911) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a
University of Cambridge Curated by ChEMBL					Assay Description Binding affinity to His6-tagged human recombinant SMARCA4 bromodomain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by VP-ITC microcalorime...				J Med Chem 59: 5095-101 (2016) Article DOI: 10.1021/acs.jmedchem.5b01997 BindingDB Entry DOI: 10.7270/Q22R3TKH
University of Cambridge Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50266286 (CHEMBL4650213) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Reverse ITC (compound as receptor). Domain start/stop: L1451-E1580				Sci Adv 1: (2015) Article DOI: 10.1126/sciadv.1500723 BindingDB Entry DOI: 10.7270/Q2S75KX6
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50158688 (CHEMBL3752911) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Binding affinity to SMARCA4 (unknown origin) by isothermal titration calorimetric analysis				J Med Chem 59: 1271-98 (2016) Article DOI: 10.1021/acs.jmedchem.5b01514 BindingDB Entry DOI: 10.7270/Q2X92D6H
Genentech Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50158688 (CHEMBL3752911) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to human SMARCA4 expressed in BL21 (DE3)-R3-BirA cells by isothermal titration calorimetry				J Med Chem 59: 4800-11 (2016) Article DOI: 10.1021/acs.jmedchem.6b00012 BindingDB Entry DOI: 10.7270/Q2G44S62
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50549127 (CHEMBL4790365) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to SMARCA4 (unknown origin) by ITC analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01242 BindingDB Entry DOI: 10.7270/Q2FR017S
TBA					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50469323 (CHEMBL4290675) Show SMILES Clc1cc(NC(=O)Nc2ccncc2)ccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Binding affinity to His6-tagged BRG1 ATPase-SnAC (658 to 1361 residues) (unknown origin) expressed in insect sf9 cells by ITC method				J Med Chem 61: 10155-10172 (2018) Article DOI: 10.1021/acs.jmedchem.8b01318 BindingDB Entry DOI: 10.7270/Q2TH8QDB
					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50184979 (CHEMBL3822689) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	417	n/a	n/a	n/a	n/a	n/a
University of Cambridge Curated by ChEMBL					Assay Description Binding affinity to His6-tagged human recombinant SMARCA4 bromodomain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by VP-ITC microcalorime...				J Med Chem 59: 5095-101 (2016) Article DOI: 10.1021/acs.jmedchem.5b01997 BindingDB Entry DOI: 10.7270/Q22R3TKH
University of Cambridge Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50598934 (CHEMBL5183240) Show SMILES Nc1nnc2c3ccccc3[nH]c2c1-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00662 BindingDB Entry DOI: 10.7270/Q2TB1BX4
TBA					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM220447 (US10633379, Compound X \| US9296741, 36) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Binding affinity to human SMARCA4 (A1448 to S1575 residues) expressed in bacterial expression system by BROMOscan assay				J Med Chem 60: 8369-8384 (2017) Article DOI: 10.1021/acs.jmedchem.7b00746 BindingDB Entry DOI: 10.7270/Q2251MB8
AbbVie Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50184981 (CHEMBL3823055) Show SMILES CCC(CC)\C=C1/CCn2c1nc(=O)c1c(Cl)cccc21 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.03E+3	n/a	n/a	n/a	n/a	n/a
University of Cambridge Curated by ChEMBL					Assay Description Binding affinity to His6-tagged human recombinant SMARCA4 bromodomain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by VP-ITC microcalorime...				J Med Chem 59: 5095-101 (2016) Article DOI: 10.1021/acs.jmedchem.5b01997 BindingDB Entry DOI: 10.7270/Q22R3TKH
University of Cambridge Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50598934 (CHEMBL5183240) Show SMILES Nc1nnc2c3ccccc3[nH]c2c1-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00662 BindingDB Entry DOI: 10.7270/Q2TB1BX4
TBA					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM179481 (US9675697, Cpd. No. 73) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	>4.00E+3	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to human partial length SMARCA4 (A1448 to S1575 residues) expressed in bacterial expression system by BROMOscan assay				J Med Chem 60: 3887-3901 (2017) Article DOI: 10.1021/acs.jmedchem.7b00193 BindingDB Entry DOI: 10.7270/Q28W3GWN
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50366670 (CHEMBL4173488) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to human SMARCA4 (A1448 to S1575 residues) expressed in bacterial expression system by BROMOScan assay				J Med Chem 61: 6110-6120 (2018) Article DOI: 10.1021/acs.jmedchem.8b00483 BindingDB Entry DOI: 10.7270/Q26M39B1
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50184981 (CHEMBL3823055) Show SMILES CCC(CC)\C=C1/CCn2c1nc(=O)c1c(Cl)cccc21 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00864 BindingDB Entry DOI: 10.7270/Q2X06C18
TBA					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM249277 (US10017501, Compound 1020-18 \| US9458145, 1020-18) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to human partial length SMARCA4 (A1448 to S1575 residues) expressed in bacterial expression system after 1 hr by bromoscan assay				Bioorg Med Chem 27: 457-469 (2019) Article DOI: 10.1016/j.bmc.2018.11.020 BindingDB Entry DOI: 10.7270/Q2HD7ZZ6
Gilead Sciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50453949 (CHEMBL4208820 \| US11247989, Example 87) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
WuXi AppTec Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity to human partial length SMARCA4 (A1448 to S1575 residues) expressed in bacterial expression system by BROMOscan assay				Bioorg Med Chem Lett 28: 15-23 (2018) Article DOI: 10.1016/j.bmcl.2017.11.025 BindingDB Entry DOI: 10.7270/Q2ZG6VVZ
WuXi AppTec Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50092310 (CHEMBL3581661 \| US9675697, Cpd. No. 23) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to biotinylated BRG1 (59 to 180 amino acid residues) (unknown origin) expressed in Rosetta2 cells by bio-layer interferometry method				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50598935 (CHEMBL5194650) Show SMILES Nc1nnc(cc1-c1ccccc1)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00662 BindingDB Entry DOI: 10.7270/Q2TB1BX4
TBA					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50148271 (CHEMBL3769590) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity to SMARCA4 in human HUT78 cell extract by chemoproteomic competition binding assay				J Med Chem 59: 1410-24 (2016) Article DOI: 10.1021/acs.jmedchem.5b00209 BindingDB Entry DOI: 10.7270/Q2PK0J09
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50504160 (CHEMBL3133807 \| US11773085, Compound B25) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PubMed	n/a	n/a	n/a	1.97E+4	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Reverse ITC (compound as receptor). Domain start/stop: L1451-E1580				Sci Adv 2: (2016) BindingDB Entry DOI: 10.7270/Q24J0JPZ
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50098311 (CHEMBL3590408) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity to SMARCA4 in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assay				J Med Chem 58: 6151-78 (2015) Article DOI: 10.1021/acs.jmedchem.5b00773 BindingDB Entry DOI: 10.7270/Q2FN17Z1
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50455480 (CHEMBL4218735) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	<3.02E+4	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Binding affinity to human partial length DNA-tagged SMARCA4 expressed in bacteria by BROMOscan method				J Med Chem 61: 4317-4334 (2018) Article DOI: 10.1021/acs.jmedchem.7b01666 BindingDB Entry DOI: 10.7270/Q27H1N6W
University of Strathclyde Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50591358 (CHEMBL5204703) Show SMILES Fc1cccc(Cl)c1C1NC(=O)c2c(Cl)cccc2N1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	6.90E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00864 BindingDB Entry DOI: 10.7270/Q2X06C18
TBA					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50591346 (CHEMBL5188924) Show SMILES Fc1cccc(Cl)c1C1NC(=O)c2ccccc2N1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	1.42E+5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00864 BindingDB Entry DOI: 10.7270/Q2X06C18
TBA					More data for this Ligand-Target Pair