Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Chromatin remodeling regulator CECR2 (Homo sapiens (Human)) | BDBM50539801 (CHEMBL4648912 | US11840533, Compound 70) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Binding affinity to human partial length CECR2 (P423 to D543 residues) expressed in bacterial expression system by BROMOscan assay | J Med Chem 63: 7186-7210 (2020) Article DOI: 10.1021/acs.jmedchem.0c00456 BindingDB Entry DOI: 10.7270/Q2PK0KPP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromatin remodeling regulator CECR2 (Homo sapiens (Human)) | BDBM50514858 (CHEMBL4577486) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to human partial length CECR2 (P423 to D543 residues) expressed in bacterial expression system by BROMOscan assay | J Med Chem 63: 5212-5241 (2020) Article DOI: 10.1021/acs.jmedchem.0c00021 BindingDB Entry DOI: 10.7270/Q2RN3C7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromatin remodeling regulator CECR2 (Homo sapiens (Human)) | BDBM50504160 (CHEMBL3133807 | US11773085, Compound B25) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | PubMed | n/a | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Binding affinity to BAZ2A (unknown origin) by isothermal titration calorimetric analysis | Sci Adv 2: (2016) BindingDB Entry DOI: 10.7270/Q24J0JPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromatin remodeling regulator CECR2 (Homo sapiens (Human)) | BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 8.80 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG Curated by ChEMBL | Assay Description Binding affinity to human CECR2 expressed in Escherichia coli L21(DE3)-R3-pRARE2 cells by BROMOScan analysis | J Med Chem 59: 4462-75 (2016) Article DOI: 10.1021/acs.jmedchem.5b01865 BindingDB Entry DOI: 10.7270/Q27H1MJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromatin remodeling regulator CECR2 (Homo sapiens (Human)) | BDBM50514899 (CHEMBL4461619) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to CECR2 (unknown origin) by ITC analysis | J Med Chem 63: 5212-5241 (2020) Article DOI: 10.1021/acs.jmedchem.0c00021 BindingDB Entry DOI: 10.7270/Q2RN3C7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromatin remodeling regulator CECR2 (Homo sapiens (Human)) | BDBM50504160 (CHEMBL3133807 | US11773085, Compound B25) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to CECR2 (unknown origin) by ITC analysis | J Med Chem 63: 5212-5241 (2020) Article DOI: 10.1021/acs.jmedchem.0c00021 BindingDB Entry DOI: 10.7270/Q2RN3C7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromatin remodeling regulator CECR2 (Homo sapiens (Human)) | BDBM50514856 (CHEMBL4465880) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to human partial length CECR2 (P423 to D543 residues) expressed in bacterial expression system by BROMOscan assay | J Med Chem 63: 5212-5241 (2020) Article DOI: 10.1021/acs.jmedchem.0c00021 BindingDB Entry DOI: 10.7270/Q2RN3C7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromatin remodeling regulator CECR2 (Homo sapiens (Human)) | BDBM50573197 (CHEMBL4872300) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to CECR2 (unknown origin) by BROMOscan method | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromatin remodeling regulator CECR2 (Homo sapiens (Human)) | BDBM50514857 (CHEMBL4449894) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to human partial length CECR2 (P423 to D543 residues) expressed in bacterial expression system by BROMOscan assay | J Med Chem 63: 5212-5241 (2020) Article DOI: 10.1021/acs.jmedchem.0c00021 BindingDB Entry DOI: 10.7270/Q2RN3C7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromatin remodeling regulator CECR2 (Homo sapiens (Human)) | BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG Curated by ChEMBL | Assay Description Binding affinity to human CECR2 expressed in Escherichia coli L21(DE3)-R3-pRARE2 cells by BROMOScan analysis | J Med Chem 59: 4462-75 (2016) Article DOI: 10.1021/acs.jmedchem.5b01865 BindingDB Entry DOI: 10.7270/Q27H1MJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromatin remodeling regulator CECR2 (Homo sapiens (Human)) | BDBM50157606 (CHEMBL3785432) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 79 | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to CECR2 (unknown origin) by ITC analysis | J Med Chem 63: 5212-5241 (2020) Article DOI: 10.1021/acs.jmedchem.0c00021 BindingDB Entry DOI: 10.7270/Q2RN3C7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromatin remodeling regulator CECR2 (Homo sapiens (Human)) | BDBM50157606 (CHEMBL3785432) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Binding affinity to CERC2 (unknown origin) by isothermal titration calorimetric analysis | J Med Chem 59: 1271-98 (2016) Article DOI: 10.1021/acs.jmedchem.5b01514 BindingDB Entry DOI: 10.7270/Q2X92D6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromatin remodeling regulator CECR2 (Homo sapiens (Human)) | BDBM50183448 (CHEMBL3823478 | US11773085, Compound B2) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 187 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG Curated by ChEMBL | Assay Description Binding affinity to human CECR2 expressed in Escherichia coli L21(DE3)-R3-pRARE2 cells by VP-ITC method | J Med Chem 59: 4462-75 (2016) Article DOI: 10.1021/acs.jmedchem.5b01865 BindingDB Entry DOI: 10.7270/Q27H1MJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromatin remodeling regulator CECR2 (Homo sapiens (Human)) | BDBM50183449 (CHEMBL3823101 | US11773085, Compound B23) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim RCV GmbH& Co KG Curated by ChEMBL | Assay Description Binding affinity to human CECR2 expressed in Escherichia coli L21(DE3)-R3-pRARE2 cells by VP-ITC method | J Med Chem 59: 4462-75 (2016) Article DOI: 10.1021/acs.jmedchem.5b01865 BindingDB Entry DOI: 10.7270/Q27H1MJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromatin remodeling regulator CECR2 (Homo sapiens (Human)) | BDBM50584925 (CHEMBL5079885) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | <316 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to human CECR2 bromodomain assessed as dissociation constant by BROMOscan method | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01871 BindingDB Entry DOI: 10.7270/Q2280CH8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromatin remodeling regulator CECR2 (Homo sapiens (Human)) | BDBM50366670 (CHEMBL4173488) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity to human CECR2 (P423 to D543 residues) expressed in bacterial expression system by BROMOscan assay | J Med Chem 61: 6110-6120 (2018) Article DOI: 10.1021/acs.jmedchem.8b00483 BindingDB Entry DOI: 10.7270/Q26M39B1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromatin remodeling regulator CECR2 (Homo sapiens (Human)) | BDBM220447 (US10633379, Compound X | US9296741, 36) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. Curated by ChEMBL | Assay Description Binding affinity to human CECR2 (P423 to D543 residues) expressed in bacterial expression system by BROMOscan assay | J Med Chem 60: 8369-8384 (2017) Article DOI: 10.1021/acs.jmedchem.7b00746 BindingDB Entry DOI: 10.7270/Q2251MB8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromatin remodeling regulator CECR2 (Homo sapiens (Human)) | BDBM50503406 (CHEMBL4463538) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a |
Genentech Inc. Curated by ChEMBL | Assay Description Binding affinity to recombinant human DNA-tagged CECR2 (423 to 543 residues) expressed in bacterial expression system by bromoscan assay | J Med Chem 61: 9301-9315 (2018) Article DOI: 10.1021/acs.jmedchem.8b01225 BindingDB Entry DOI: 10.7270/Q2NV9NH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromatin remodeling regulator CECR2 (Homo sapiens (Human)) | BDBM179481 (US9675697, Cpd. No. 73) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a |
University of Michigan Curated by ChEMBL | Assay Description Binding affinity to human partial length CECR2 (P423 to D543 residues) expressed in bacterial expression system by BROMOscan assay | J Med Chem 60: 3887-3901 (2017) Article DOI: 10.1021/acs.jmedchem.7b00193 BindingDB Entry DOI: 10.7270/Q28W3GWN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromatin remodeling regulator CECR2 (Homo sapiens (Human)) | BDBM249277 (US10017501, Compound 1020-18 | US9458145, 1020-18) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 8.20E+3 | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. Curated by ChEMBL | Assay Description Binding affinity to human partial length CECR2 (P423 to D543 residues) expressed in bacterial expression system after 1 hr by bromoscan assay | Bioorg Med Chem 27: 457-469 (2019) Article DOI: 10.1016/j.bmc.2018.11.020 BindingDB Entry DOI: 10.7270/Q2HD7ZZ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromatin remodeling regulator CECR2 (Homo sapiens (Human)) | BDBM50453949 (CHEMBL4208820 | US11247989, Example 87) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
WuXi AppTec Co., Ltd. Curated by ChEMBL | Assay Description Binding affinity to human partial length CECR2 (P423 to D543 residues) expressed in bacterial expression system by BROMOscan assay | Bioorg Med Chem Lett 28: 15-23 (2018) Article DOI: 10.1016/j.bmcl.2017.11.025 BindingDB Entry DOI: 10.7270/Q2ZG6VVZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chromatin remodeling regulator CECR2 (Homo sapiens (Human)) | BDBM50455480 (CHEMBL4218735) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | <3.02E+4 | n/a | n/a | n/a | n/a | n/a |
University of Strathclyde Curated by ChEMBL | Assay Description Binding affinity to human partial length DNA-tagged CECR2 expressed in bacteria by BROMOscan method | J Med Chem 61: 4317-4334 (2018) Article DOI: 10.1021/acs.jmedchem.7b01666 BindingDB Entry DOI: 10.7270/Q27H1N6W | |||||||||||
More data for this Ligand-Target Pair |