Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tubulin beta chain (Sus scrofa) | BDBM50485036 (CHEMBL2024544) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Pharmacy and Life Sciences Curated by ChEMBL | Assay Description Binding affinity to porcine tubulin after 1 hr by spectrofluorometric analysis | J Med Chem 55: 1056-71 (2012) Article DOI: 10.1021/jm2009088 BindingDB Entry DOI: 10.7270/Q20R9S8Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin beta chain (Sus scrofa) | BDBM50485035 (CHEMBL2024561) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Pharmacy and Life Sciences Curated by ChEMBL | Assay Description Binding affinity to porcine tubulin after 1 hr by spectrofluorometric analysis | J Med Chem 55: 1056-71 (2012) Article DOI: 10.1021/jm2009088 BindingDB Entry DOI: 10.7270/Q20R9S8Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin beta chain (Sus scrofa) | BDBM50030765 (NPI-2358 | Plinabulin) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 1.06E+3 | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Pharmacy and Life Sciences Curated by ChEMBL | Assay Description Binding affinity to porcine tubulin after 1 hr by spectrofluorometric analysis | Bioorg Med Chem 19: 595-602 (2011) Article DOI: 10.1016/j.bmc.2010.10.055 BindingDB Entry DOI: 10.7270/Q2WS8X2Q | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Tubulin beta chain (Sus scrofa) | BDBM50030765 (NPI-2358 | Plinabulin) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 1.06E+3 | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Pharmacy and Life Sciences Curated by ChEMBL | Assay Description Binding affinity to pig tubulin after 1 hr by fluorescence quenching analysis | Bioorg Med Chem 18: 3169-74 (2010) Article DOI: 10.1016/j.bmc.2010.03.037 BindingDB Entry DOI: 10.7270/Q2QR50Z5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Tubulin beta chain (Sus scrofa) | BDBM50030765 (NPI-2358 | Plinabulin) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 1.06E+3 | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Pharmacy and Life Sciences Curated by ChEMBL | Assay Description Binding affinity to porcine tubulin after 1 hr by spectrofluorometric analysis | J Med Chem 55: 1056-71 (2012) Article DOI: 10.1021/jm2009088 BindingDB Entry DOI: 10.7270/Q20R9S8Q | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Tubulin beta chain (Sus scrofa) | BDBM50030766 (CHEMBL3342339) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Pharmacy and Life Sciences Curated by ChEMBL | Assay Description Binding affinity to porcine tubulin incubated for 1 hr by spectrofluorometry | ACS Med Chem Lett 5: 1094-8 (2014) Article DOI: 10.1021/ml5001883 BindingDB Entry DOI: 10.7270/Q2R49SCP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin beta chain (Sus scrofa) | BDBM50520178 (CHEMBL4468642) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 2.66E+3 | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Binding affinity to porcine brain tubulin polymerization by surface plasmon analysis analysis | J Med Chem 63: 827-846 (2020) Article DOI: 10.1021/acs.jmedchem.9b01815 BindingDB Entry DOI: 10.7270/Q280560G | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Tubulin beta chain (Sus scrofa) | BDBM50014846 ((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Pharmacy and Life Sciences Curated by ChEMBL | Assay Description Binding affinity to porcine tubulin after 1 hr by spectrofluorometric analysis | Bioorg Med Chem 19: 595-602 (2011) Article DOI: 10.1016/j.bmc.2010.10.055 BindingDB Entry DOI: 10.7270/Q2WS8X2Q | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Tubulin beta chain (Sus scrofa) | BDBM50482143 (CHEMBL1077255 | KPU-244-B2) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 9.74E+3 | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Pharmacy and Life Sciences Curated by ChEMBL | Assay Description Binding affinity to pig tubulin after 1 hr by fluorescence quenching analysis | Bioorg Med Chem 18: 3169-74 (2010) Article DOI: 10.1016/j.bmc.2010.03.037 BindingDB Entry DOI: 10.7270/Q2QR50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin beta chain (Sus scrofa) | BDBM50014846 ((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 1.13E+4 | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Binding affinity to porcine brain tubulin polymerization by surface plasmon analysis analysis | J Med Chem 63: 827-846 (2020) Article DOI: 10.1021/acs.jmedchem.9b01815 BindingDB Entry DOI: 10.7270/Q280560G | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Tubulin beta chain (Sus scrofa) | BDBM50483308 (CHEMBL1643852) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.79E+4 | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Pharmacy and Life Sciences Curated by ChEMBL | Assay Description Binding affinity to porcine tubulin after 1 hr by spectrofluorometric analysis | Bioorg Med Chem 19: 595-602 (2011) Article DOI: 10.1016/j.bmc.2010.10.055 BindingDB Entry DOI: 10.7270/Q2WS8X2Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin beta chain (Sus scrofa) | BDBM50482142 (CHEMBL1096312 | KPU-244-B3) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 2.52E+4 | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Pharmacy and Life Sciences Curated by ChEMBL | Assay Description Binding affinity to pig tubulin after 1 hr by fluorescence quenching analysis | Bioorg Med Chem 18: 3169-74 (2010) Article DOI: 10.1016/j.bmc.2010.03.037 BindingDB Entry DOI: 10.7270/Q2QR50Z5 | |||||||||||
More data for this Ligand-Target Pair |