Compile Data Set for Download or QSAR

Found 10 hits of kd data for polymerid = 50006817,5746,5747,8276   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50318382 (3-[pyridine-2-yl)ethynyl]cyclohex-2-enone-O-fluoro...) Show SMILES FCCOCCO\N=C1/CCCC(=C1)C#Cc1ccccn1 |c:12| Show InChI InChI=1S/C17H19FN2O2/c18-9-11-21-12-13-22-20-17-6-3-4-15(14-17)7-8-16-5-1-2-10-19-16/h1-2,5,10,14H,3-4,6,9,11-13H2/b20-17+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a
ETH Zurich Curated by ChEMBL					Assay Description Binding affinity to mGluR5 ligand binding site 1 in Sprague-Dawley rat brain P2 membrane after 45 mins by gamma counting				J Med Chem 53: 4009-17 (2010) Article DOI: 10.1021/jm901850k BindingDB Entry DOI: 10.7270/Q2T72HMH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50395923 (CHEMBL2164550) Show SMILES Fc1ccc(nc1)-c1noc(n1)-c1cc(F)cc(c1)C#N Show InChI InChI=1S/C14H6F2N4O/c15-10-1-2-12(18-7-10)13-19-14(21-20-13)9-3-8(6-17)4-11(16)5-9/h1-5,7H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.25	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to human mGluR5 expressed in HEK293 cell membranes expressing GLAST by scintillation counting				Bioorg Med Chem Lett 22: 6974-9 (2012) Article DOI: 10.1016/j.bmcl.2012.08.100 BindingDB Entry DOI: 10.7270/Q2BP03WH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50198702 ((E)-3-((6-methylpyridin-2-yl)ethynyl)cyclohex-2-en...) Show SMILES CO\N=C1/CCCC(=C1)C#Cc1cccc(C)n1 |c:7| Show InChI InChI=1S/C15H16N2O/c1-12-5-3-7-14(16-12)10-9-13-6-4-8-15(11-13)17-18-2/h3,5,7,11H,4,6,8H2,1-2H3/b17-15+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Binding affinity at mGluR5 in rat brain membrane				Bioorg Med Chem 15: 903-14 (2006) Article DOI: 10.1016/j.bmc.2006.10.038 BindingDB Entry DOI: 10.7270/Q25D8SNC
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50395923 (CHEMBL2164550) Show SMILES Fc1ccc(nc1)-c1noc(n1)-c1cc(F)cc(c1)C#N Show InChI InChI=1S/C14H6F2N4O/c15-10-1-2-12(18-7-10)13-19-14(21-20-13)9-3-8(6-17)4-11(16)5-9/h1-5,7H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to human mGluR5 expressed in HEK293 cell membranes expressing GLAST after 1 hr by scintillation counter in absence of MPEP				Bioorg Med Chem Lett 22: 6974-9 (2012) Article DOI: 10.1016/j.bmcl.2012.08.100 BindingDB Entry DOI: 10.7270/Q2BP03WH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50395923 (CHEMBL2164550) Show SMILES Fc1ccc(nc1)-c1noc(n1)-c1cc(F)cc(c1)C#N Show InChI InChI=1S/C14H6F2N4O/c15-10-1-2-12(18-7-10)13-19-14(21-20-13)9-3-8(6-17)4-11(16)5-9/h1-5,7H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to human mGluR5 expressed in HEK293 cell membranes expressing GLAST after 1 hr by scintillation counter in presence of 10 nM MPEP				Bioorg Med Chem Lett 22: 6974-9 (2012) Article DOI: 10.1016/j.bmcl.2012.08.100 BindingDB Entry DOI: 10.7270/Q2BP03WH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50395923 (CHEMBL2164550) Show SMILES Fc1ccc(nc1)-c1noc(n1)-c1cc(F)cc(c1)C#N Show InChI InChI=1S/C14H6F2N4O/c15-10-1-2-12(18-7-10)13-19-14(21-20-13)9-3-8(6-17)4-11(16)5-9/h1-5,7H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to human mGluR5 expressed in HEK293 cell membranes expressing GLAST after 1 hr by scintillation counter in presence of 20 nM MPEP				Bioorg Med Chem Lett 22: 6974-9 (2012) Article DOI: 10.1016/j.bmcl.2012.08.100 BindingDB Entry DOI: 10.7270/Q2BP03WH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50084137 (2-Methyl-6-(phenylethynyl)pyridine | 2-Methyl-6-ph...) Show SMILES Cc1cccc(n1)C#Cc1ccccc1 Show InChI InChI=1S/C14H11N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-9H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to human mGluR5 expressed in HEK293 cell membranes expressing GLAST by scintillation counting				Bioorg Med Chem Lett 22: 6974-9 (2012) Article DOI: 10.1016/j.bmcl.2012.08.100 BindingDB Entry DOI: 10.7270/Q2BP03WH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50395923 (CHEMBL2164550) Show SMILES Fc1ccc(nc1)-c1noc(n1)-c1cc(F)cc(c1)C#N Show InChI InChI=1S/C14H6F2N4O/c15-10-1-2-12(18-7-10)13-19-14(21-20-13)9-3-8(6-17)4-11(16)5-9/h1-5,7H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to mGluR5 in Sprague-Dawley rat striatum after 60 mins by autoradiographic analysis				Bioorg Med Chem Lett 22: 6974-9 (2012) Article DOI: 10.1016/j.bmcl.2012.08.100 BindingDB Entry DOI: 10.7270/Q2BP03WH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50318382 (3-[pyridine-2-yl)ethynyl]cyclohex-2-enone-O-fluoro...) Show SMILES FCCOCCO\N=C1/CCCC(=C1)C#Cc1ccccn1 |c:12| Show InChI InChI=1S/C17H19FN2O2/c18-9-11-21-12-13-22-20-17-6-3-4-15(14-17)7-8-16-5-1-2-10-19-16/h1-2,5,10,14H,3-4,6,9,11-13H2/b20-17+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	13.7	n/a	n/a	n/a	n/a	n/a
ETH Zurich Curated by ChEMBL					Assay Description Binding affinity to mGluR5 ligand binding site 2 in Sprague-Dawley rat brain P2 membrane after 45 mins by gamma counting				J Med Chem 53: 4009-17 (2010) Article DOI: 10.1021/jm901850k BindingDB Entry DOI: 10.7270/Q2T72HMH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50395544 (CHEMBL2164788) Show SMILES CCO\N=C1/C=C(CCC1F)C#Cc1ccccn1 |c:5| Show InChI InChI=1S/C15H15FN2O/c1-2-19-18-15-11-12(7-9-14(15)16)6-8-13-5-3-4-10-17-13/h3-5,10-11,14H,2,7,9H2,1H3/b18-15+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a
Institute of Technology (ETH) Zurich Curated by ChEMBL					Assay Description Binding affinity to mGluR5 receptor in Sprague-Dawley rat brain by beta counting				J Med Chem 55: 7154-62 (2012) Article DOI: 10.1021/jm300648b BindingDB Entry DOI: 10.7270/Q2ST7QZX
					More data for this Ligand-Target Pair